Search Results - (Author, Cooperation:M. Hahn)

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  1. 1
    Staff View
    Publication Date:
    2018-01-04
    Publisher:
    The American Association for Cancer Research (AACR)
    Print ISSN:
    0008-5472
    Electronic ISSN:
    1538-7445
    Topics:
    Medicine
    Published by:
    http://www.aacr.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    M. Patzold ; T. P. Andert ; S. W. Asmar ; J. D. Anderson ; J. P. Barriot ; M. K. Bird ; B. Hausler ; M. Hahn ; S. Tellmann ; H. Sierks ; P. Lamy ; B. P. Weiss
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-10-29
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2015-03-11
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Antigens, CD274/*antagonists & inhibitors/metabolism ; CTLA-4 Antigen/*antagonists & inhibitors ; Cell Cycle Checkpoints/*drug effects ; Female ; Humans ; Melanoma/*drug therapy/*immunology/pathology/*radiotherapy ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Receptors, Antigen, T-Cell/drug effects/immunology/metabolism ; T-Lymphocytes/cytology/*drug effects/immunology/*radiation effects ; T-Lymphocytes, Regulatory/drug effects/immunology/radiation effects
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    A. Hayashi-Takagi ; S. Yagishita ; M. Nakamura ; F. Shirai ; Y. I. Wu ; A. L. Loshbaugh ; B. Kuhlman ; K. M. Hahn ; H. Kasai
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-09-10
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Dendritic Spines/physiology/radiation effects ; Hippocampus/cytology/physiology/radiation effects ; In Vitro Techniques ; Light ; Long-Term Potentiation/physiology/radiation effects ; Male ; Memory/*physiology/*radiation effects ; Mice ; Molecular Probes ; Motor Cortex/cytology/*physiology/*radiation effects ; Motor Skills/physiology/radiation effects ; Neuronal Plasticity/*physiology/*radiation effects ; Rotarod Performance Test ; Spatio-Temporal Analysis ; Synapses/*physiology/*radiation effects
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2018-03-07
    Publisher:
    BioMed Central
    Electronic ISSN:
    1741-7007
    Topics:
    Biology
    Published by:
    http://www.biomedcentral.com/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2018-10-03
    Publisher:
    Nature Publishing Group (NPG)
    Electronic ISSN:
    2041-1723
    Topics:
    Biology
    Chemistry and Pharmacology
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    S. A. Stern ; F. Bagenal ; K. Ennico ; G. R. Gladstone ; W. M. Grundy ; W. B. McKinnon ; J. M. Moore ; C. B. Olkin ; J. R. Spencer ; H. A. Weaver ; L. A. Young ; T. Andert ; J. Andrews ; M. Banks ; B. Bauer ; J. Bauman ; O. S. Barnouin ; P. Bedini ; K. Beisser ; R. A. Beyer ; S. Bhaskaran ; R. P. Binzel ; E. Birath ; M. Bird ; D. J. Bogan ; A. Bowman ; V. J. Bray ; M. Brozovic ; C. Bryan ; M. R. Buckley ; M. W. Buie ; B. J. Buratti ; S. S. Bushman ; A. Calloway ; B. Carcich ; A. F. Cheng ; S. Conard ; C. A. Conrad ; J. C. Cook ; D. P. Cruikshank ; O. S. Custodio ; C. M. Dalle Ore ; C. Deboy ; Z. J. Dischner ; P. Dumont ; A. M. Earle ; H. A. Elliott ; J. Ercol ; C. M. Ernst ; T. Finley ; S. H. Flanigan ; G. Fountain ; M. J. Freeze ; T. Greathouse ; J. L. Green ; Y. Guo ; M. Hahn ; D. P. Hamilton ; S. A. Hamilton ; J. Hanley ; A. Harch ; H. M. Hart ; C. B. Hersman ; A. Hill ; M. E. Hill ; D. P. Hinson ; M. E. Holdridge ; M. Horanyi ; A. D. Howard ; C. J. Howett ; C. Jackman ; R. A. Jacobson ; D. E. Jennings ; J. A. Kammer ; H. K. Kang ; D. E. Kaufmann ; P. Kollmann ; S. M. Krimigis ; D. Kusnierkiewicz ; T. R. Lauer ; J. E. Lee ; K. L. Lindstrom ; I. R. Linscott ; C. M. Lisse ; A. W. Lunsford ; V. A. Mallder ; N. Martin ; D. J. McComas ; R. L. McNutt, Jr. ; D. Mehoke ; T. Mehoke ; E. D. Melin ; M. Mutchler ; D. Nelson ; F. Nimmo ; J. I. Nunez ; A. Ocampo ; W. M. Owen ; M. Paetzold ; B. Page ; A. H. Parker ; J. W. Parker ; F. Pelletier ; J. Peterson ; N. Pinkine ; M. Piquette ; S. B. Porter ; S. Protopapa ; J. Redfern ; H. J. Reitsema ; D. C. Reuter ; J. H. Roberts ; S. J. Robbins ; G. Rogers ; D. Rose ; K. Runyon ; K. D. Retherford ; M. G. Ryschkewitsch ; P. Schenk ; E. Schindhelm ; B. Sepan ; M. R. Showalter ; K. N. Singer ; M. Soluri ; D. Stanbridge ; A. J. Steffl ; D. F. Strobel ; T. Stryk ; M. E. Summers ; J. R. Szalay ; M. Tapley ; A. Taylor ; H. Taylor ; H. B. Throop ; C. C. Tsang ; G. L. Tyler ; O. M. Umurhan ; A. J. Verbiscer ; M. H. Versteeg ; M. Vincent ; R. Webbert ; S. Weidner ; G. E. Weigle, 2nd ; O. L. White ; K. Whittenburg ; B. G. Williams ; K. Williams ; S. Williams ; W. W. Woods ; A. M. Zangari ; E. Zirnstein
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-10-17
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Staff View
    Publication Date:
    2013-02-05
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Antigens, Polyomavirus Transforming/genetics/metabolism ; Cell Aging/*immunology ; Cell Cycle ; Cell Proliferation ; Cyclin-Dependent Kinase Inhibitor p16/deficiency/genetics/metabolism ; Cytokines/*immunology ; Disease Models, Animal ; Disease Progression ; Female ; Humans ; Interferon-gamma/immunology ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Mice, Transgenic ; Neoplasms/*immunology/*pathology ; Oncogenes/genetics ; Phosphoserine/metabolism ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Retinoblastoma Protein/chemistry/metabolism ; STAT1 Transcription Factor/metabolism ; Th1 Cells/*immunology ; Time Factors ; Tumor Cells, Cultured ; Tumor Necrosis Factor-alpha/immunology ; Tumor Suppressor Protein p53/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Staff View
    Publication Date:
    2018-11-02
    Publisher:
    American Society of Hematology (ASH)
    Print ISSN:
    0006-4971
    Electronic ISSN:
    1528-0020
    Topics:
    Biology
    Medicine
    Keywords:
    Platelets and Thrombopoiesis, Thrombosis and Hemostasis
    Published by:
    http://www.hematology.org/

    Latest Papers from Table of Contents or Articles in Press
  10. 10
    Staff View
    Publication Date:
    2016-02-06
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  11. 11
    Staff View
    Type of Medium:
    article
    Publication Date:
    1995
    Keywords:
    Sozialhilfe ; Erziehungshilfe ; Kind ; Schule ; Konzeption ; Jugendlicher ; Zielgruppe
    In:
    Schriftenreihe / EREV, Bd. 36 (1995) H. 1, S. 96-104, 0943-4984
    Language:
    German

    FIS Bildung Literaturdatenbank
  12. 12
    Staff View
    Type of Medium:
    article
    Publication Date:
    1995
    Keywords:
    Leistungsfähigkeit ; Förderungsmaßnahme ; Erziehungshilfe ; Kind ; Jugendhilfe ; Kooperation ; Individuum
    In:
    Schriftenreihe / EREV, Bd. 36 (1995) H. 1, S. 89-94, 0943-4984
    Language:
    German

    FIS Bildung Literaturdatenbank
  13. 13
    Staff View
    Type of Medium:
    article
    Publication Date:
    1984
    Keywords:
    Problemorientierter Unterricht ; Religionsunterricht ; Religionspädagogik ; Entwicklung ; Konferenzschrift
    In:
    Religion heute, (1984) H. 2, S. 74, 0722-9151
    Language:
    German

    FIS Bildung Literaturdatenbank
  14. 14
    Staff View
    Publication Date:
    2018-01-31
    Publisher:
    The American Society for Microbiology (ASM)
    Print ISSN:
    0022-538X
    Electronic ISSN:
    1098-5514
    Topics:
    Medicine
    Published by:
    http://www.asm.org/

    Latest Papers from Table of Contents or Articles in Press
  15. 15
    Hahn, M. Y. ; Schriver, K. E. ; Whetten, R. L.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1988
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    Efficient multiple ionization of large benzene clusters has been observed following irradiation of a supersonic cluster beam by ArF-laser pulses at low fluences. The mechanism of multiple ionization is shown to be distinct from that believed to predominate in electron impact or synchrotron ionization experiments. The fluence dependence is instead interpreted by considering independent ionization of molecules within the cluster. The efficiency of multiple ionization over a range of laser fluence can be predicted quantitatively using a recently proposed exciton annihilation model, and explains the 106 enhancement of the double ionization rate over the molecular value. The critical sizes N*(z) for stability of a z-charged drop with respect to Coulomb fission are N*(2)=23, N*(3)=52, and N*(4)=92 and can be accounted for by liquid drop models. However, the fission of doubly charged clusters could not be detected in dynamical mass spectrometry experiments on the 10−6 to 10−4 s time scale. The surprising critical aspect of the fission rate is discussed, and arguments are made in favor of the Gay–Berne dynamical mechanism.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.453832

    Articles: DFG German National Licenses
  16. 16
    Sun, J. Z. ; Char, K. ; Hahn, M. R. ; Geballe, T. H. ; Kapitulnik, A.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1989
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    High Tc superconductors exhibit significant flux motion due to a thermally activated creep process. The motion of the fluxoids dissipates energy. This dissipation causes a broadening of the resistive transition below Tc in a magnetic field as well as a logarithmic decay of the diamagnetic shielding moment in time. From the detailed structure of the broadened transition, empirical parameters are derived. The pinning strength is highly anisotropic, reflecting the anisotropy of the coherence length. Implications of an extraordinarily low activation energy are also addressed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.101465

    Articles: DFG German National Licenses
  17. 17
    Hahn, M. ; Lischka, G. ; Pfeifle, J. ; Wirth, V.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1600-0536
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0536.1995.tb00851.x

    Articles: DFG German National Licenses
  18. 18
    Ju, S. S. ; Cheng, P. Y. ; Hahn, M. Y. ; Dai, H. L.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1995
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    Acetylene⋅Ar complex in the S1 state has been characterized through laser fluorescence excitation spectra in the acetylene A˜←X˜, 3n0 (n=0–4) bands region. Two isomeric structures have been determined for the acetylene(A˜)⋅Ar complex from rotational band analysis, even though only one structure was known to exist for the ground state acetylene(X˜)⋅Ar. The in-plane isomer has the Ar atom situated in the molecular plane of the trans-bent acetylene, 3.77 A(ring) from the acetylene center of mass and tilted from the H atoms. The out-of-plane isomeric structure, directly inverted from the rotational constants, has argon 3.76 A(ring) away from the acetylene center of mass and 18° tilted from the C2 rotational axis. This structure is most likely due to large amplitude bending motions away from the equilibrium position which is along the C2 axis. Axis switching effect in the rotational band analysis for both isomers has been examined and found to be negligible. (Formulas for calculating the three-dimensional axis switching angles are detailed in the Appendix.) Three van der Waals vibrational mode frequencies have been determined from the vibrational progressions in the spectra; the stretching fundamental of the out-of-plane isomer is 28 cm−1; the in-plane bending fundamental, and the out-of-plane bending first overtone of the in-plane isomer are 11 and 17 cm−1, respectively.The isomeric structures have been compared with the results from a pairwise-atom potential calculation with parameters transferred from the ones previously derived for C2H4⋅Ar potential calculations. It was found that when the set of parameters that most closely reflects the electronic density distribution in C2H2(A˜) orbitals was used, two potential minima mimicking the two isomeric structures were generated. This potential calculation can even qualitatively reproduce the complex spectral shift induced by the ν3 mode excitation in acetylene. Combining the observed spectral shifts and previous experimental and theoretical studies of acetylene(X˜)⋅Ar, we have estimated the binding energy of the out-of-plane C2H2(A˜)⋅Ar isomer to be 179 cm−1, and that of the in-plane isomer to be 170 cm−1. © 1995 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.470723

    Articles: DFG German National Licenses
  19. 19
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Thrombopoietin (TPO) is one of the most promising stimulants for ex vivo expansion of haematopoietic stem cells. Previously, we have found that TPO induces a characteristic pattern of apoptosis during ex vivo expansion of human cord blood (CB) CD34+ cells and that the TPO-induced apoptotic cells belong to megakaryocyte (MK) lineage. In this study, we have examined the maturation of MK and platelet production in association with the TPO-induced apoptosis. CD34+ cells, purified from human CB, were expanded in serum-free conditions stimulated with TPO. Apoptosis was confirmed by terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate-biotin nick end labelling (TUNEL) assay and electron microscopy (EM). Simultaneous measurement of DNA content and immunophenotyping revealed that the cells with higher DNA content (〉8 N) constituted less than 5% of the CD41+ fractions until day 14, implying premature apoptosis of MKs before full polyploidization. Nevertheless, EM observation showed not only platelet territories but also newly produced platelets in which granules and microfilaments could be identified. Furthermore, flow cytometry demonstrated that the platelet fraction expressed P-selectin and an activation motif on GPIIb/IIIa recognized by monoclonal antibody PAC-1 upon stimulation with adenosine diphosphate (ADP). In addition, periodic acid-Schiff (PAS)-positive materials and nonspecific esterase activities could be demonstrated. Therefore, it is suggested that platelet production and the accompanying processes, rather than apoptosis only, be hastened during the ex vivo expansion of CB CD34+ cells when using TPO.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-3083.2002.01031.x

    Articles: DFG German National Licenses
  20. 20
    Gieseler, R. K. ; Marquitan, G. ; Hahn, M. J. ; Perdon, L. A. ; Driessen, W. H. P. ; Sullivan, S. M. ; Scolaro, M. J.

    Oxford, UK; Malden, USA : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Myeloid dendritic cells (MyDCs), prime stimulators of antigen-specific immunity, can serve as one of the major reservoirs for human immunodeficiency virus type-1 (HIV-1). Utilizing mature monocyte-derived MyDCs generated with granulocyte/macrophage colony-stimulating factor, interleukin-4, and tumour necrosis factor-α as an in vitro model, we here present the first proof of concept for liposomal compound delivery to these cells by specifically addressing CD209, i.e. DC-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN), a MyDC-associated C-type lectin implicated in the transmission of HIV-1 to T helper cells. By employing a liposomally entrapped tracer, calcein, we demonstrate by flow cytometry and mathematics a superior targeting efficacy for DC-SIGN, as compared with select other MyDC markers (CD1a, CD4, CD45R0, and CD83). Fluorescence microscopy reveals time-dependent surface binding and intracellular uptake of DC-SIGN-specific liposomes by both immature and mature MyDCs. This pilot study implies that liposomal targeting to CD209 and related C-type lectins may afford therapeutic intracellular drug delivery to MyDCs and other reservoir and nonreservoir cells susceptible to infection with HIV-1.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.0300-9475.2004.01431.x

    Articles: DFG German National Licenses