Search Results - (Author, Cooperation:M. H. Chen)
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1G. B. Ehret ; P. B. Munroe ; K. M. Rice ; M. Bochud ; A. D. Johnson ; D. I. Chasman ; A. V. Smith ; M. D. Tobin ; G. C. Verwoert ; S. J. Hwang ; V. Pihur ; P. Vollenweider ; P. F. O'Reilly ; N. Amin ; J. L. Bragg-Gresham ; A. Teumer ; N. L. Glazer ; L. Launer ; J. H. Zhao ; Y. Aulchenko ; S. Heath ; S. Sober ; A. Parsa ; J. Luan ; P. Arora ; A. Dehghan ; F. Zhang ; G. Lucas ; A. A. Hicks ; A. U. Jackson ; J. F. Peden ; T. Tanaka ; S. H. Wild ; I. Rudan ; W. Igl ; Y. Milaneschi ; A. N. Parker ; C. Fava ; J. C. Chambers ; E. R. Fox ; M. Kumari ; M. J. Go ; P. van der Harst ; W. H. Kao ; M. Sjogren ; D. G. Vinay ; M. Alexander ; Y. Tabara ; S. Shaw-Hawkins ; P. H. Whincup ; Y. Liu ; G. Shi ; J. Kuusisto ; B. Tayo ; M. Seielstad ; X. Sim ; K. D. Nguyen ; T. Lehtimaki ; G. Matullo ; Y. Wu ; T. R. Gaunt ; N. C. Onland-Moret ; M. N. Cooper ; C. G. Platou ; E. Org ; R. Hardy ; S. Dahgam ; J. Palmen ; V. Vitart ; P. S. Braund ; T. Kuznetsova ; C. S. Uiterwaal ; A. Adeyemo ; W. Palmas ; H. Campbell ; B. Ludwig ; M. Tomaszewski ; I. Tzoulaki ; N. D. Palmer ; T. Aspelund ; M. Garcia ; Y. P. Chang ; J. R. O'Connell ; N. I. Steinle ; D. E. Grobbee ; D. E. Arking ; S. L. Kardia ; A. C. Morrison ; D. Hernandez ; S. Najjar ; W. L. McArdle ; D. Hadley ; M. J. Brown ; J. M. Connell ; A. D. Hingorani ; I. N. Day ; D. A. Lawlor ; J. P. Beilby ; R. W. Lawrence ; R. Clarke ; J. C. Hopewell ; H. Ongen ; A. W. Dreisbach ; Y. Li ; J. H. Young ; J. C. Bis ; M. Kahonen ; J. Viikari ; L. S. Adair ; N. R. Lee ; M. H. Chen ; M. Olden ; C. Pattaro ; J. A. Bolton ; A. Kottgen ; S. Bergmann ; V. Mooser ; N. Chaturvedi ; T. M. Frayling ; M. Islam ; T. H. Jafar ; J. Erdmann ; S. R. Kulkarni ; S. R. Bornstein ; J. Grassler ; L. Groop ; B. F. Voight ; J. Kettunen ; P. Howard ; A. Taylor ; S. Guarrera ; F. Ricceri ; V. Emilsson ; A. Plump ; I. Barroso ; K. T. Khaw ; A. B. Weder ; S. C. Hunt ; Y. V. Sun ; R. N. Bergman ; F. S. Collins ; L. L. Bonnycastle ; L. J. Scott ; H. M. Stringham ; L. Peltonen ; M. Perola ; E. Vartiainen ; S. M. Brand ; J. A. Staessen ; T. J. Wang ; P. R. Burton ; M. Soler Artigas ; Y. Dong ; H. Snieder ; X. Wang ; H. Zhu ; K. K. Lohman ; M. E. Rudock ; S. R. Heckbert ; N. L. Smith ; K. L. Wiggins ; A. Doumatey ; D. Shriner ; G. Veldre ; M. Viigimaa ; S. Kinra ; D. Prabhakaran ; V. Tripathy ; C. D. Langefeld ; A. Rosengren ; D. S. Thelle ; A. M. Corsi ; A. Singleton ; T. Forrester ; G. Hilton ; C. A. McKenzie ; T. Salako ; N. Iwai ; Y. Kita ; T. Ogihara ; T. Ohkubo ; T. Okamura ; H. Ueshima ; S. Umemura ; S. Eyheramendy ; T. Meitinger ; H. E. Wichmann ; Y. S. Cho ; H. L. Kim ; J. Y. Lee ; J. Scott ; J. S. Sehmi ; W. Zhang ; B. Hedblad ; P. Nilsson ; G. D. Smith ; A. Wong ; N. Narisu ; A. Stancakova ; L. J. Raffel ; J. Yao ; S. Kathiresan ; C. J. O'Donnell ; S. M. Schwartz ; M. A. Ikram ; W. T. Longstreth, Jr. ; T. H. Mosley ; S. Seshadri ; N. R. Shrine ; L. V. Wain ; M. A. Morken ; A. J. Swift ; J. Laitinen ; I. Prokopenko ; P. Zitting ; J. A. Cooper ; S. E. Humphries ; J. Danesh ; A. Rasheed ; A. Goel ; A. Hamsten ; H. Watkins ; S. J. Bakker ; W. H. van Gilst ; C. S. Janipalli ; K. R. Mani ; C. S. Yajnik ; A. Hofman ; F. U. Mattace-Raso ; B. A. Oostra ; A. Demirkan ; A. Isaacs ; F. Rivadeneira ; E. G. Lakatta ; M. Orru ; A. Scuteri ; M. Ala-Korpela ; A. J. Kangas ; L. P. Lyytikainen ; P. Soininen ; T. Tukiainen ; P. Wurtz ; R. T. Ong ; M. Dorr ; H. K. Kroemer ; U. Volker ; H. Volzke ; P. Galan ; S. Hercberg ; M. Lathrop ; D. Zelenika ; P. Deloukas ; M. Mangino ; T. D. Spector ; G. Zhai ; J. F. Meschia ; M. A. Nalls ; P. Sharma ; J. Terzic ; M. V. Kumar ; M. Denniff ; E. Zukowska-Szczechowska ; L. E. Wagenknecht ; F. G. Fowkes ; F. J. Charchar ; P. E. Schwarz ; C. Hayward ; X. Guo ; C. Rotimi ; M. L. Bots ; E. Brand ; N. J. Samani ; O. Polasek ; P. J. Talmud ; F. Nyberg ; D. Kuh ; M. Laan ; K. Hveem ; L. J. Palmer ; Y. T. van der Schouw ; J. P. Casas ; K. L. Mohlke ; P. Vineis ; O. Raitakari ; S. K. Ganesh ; T. Y. Wong ; E. S. Tai ; R. S. Cooper ; M. Laakso ; D. C. Rao ; T. B. Harris ; R. W. Morris ; A. F. Dominiczak ; M. Kivimaki ; M. G. Marmot ; T. Miki ; D. Saleheen ; G. R. Chandak ; J. Coresh ; G. Navis ; V. Salomaa ; B. G. Han ; X. Zhu ; J. S. Kooner ; O. Melander ; P. M. Ridker ; S. Bandinelli ; U. B. Gyllensten ; A. F. Wright ; J. F. Wilson ; L. Ferrucci ; M. Farrall ; J. Tuomilehto ; P. P. Pramstaller ; R. Elosua ; N. Soranzo ; E. J. Sijbrands ; D. Altshuler ; R. J. Loos ; A. R. Shuldiner ; C. Gieger ; P. Meneton ; A. G. Uitterlinden ; N. J. Wareham ; V. Gudnason ; J. I. Rotter ; R. Rettig ; M. Uda ; D. P. Strachan ; J. C. Witteman ; A. L. Hartikainen ; J. S. Beckmann ; E. Boerwinkle ; R. S. Vasan ; M. Boehnke ; M. G. Larson ; M. R. Jarvelin ; B. M. Psaty ; G. R. Abecasis ; A. Chakravarti ; P. Elliott ; C. M. van Duijn ; C. Newton-Cheh ; D. Levy ; M. J. Caulfield ; T. Johnson
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-09-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Africa/ethnology ; Asia/ethnology ; Blood Pressure/*genetics/physiology ; Cardiovascular Diseases/*genetics ; Coronary Artery Disease/genetics ; Europe/ethnology ; Genetic Predisposition to Disease/*genetics ; Genome-Wide Association Study ; Humans ; Hypertension/genetics ; Kidney Diseases/genetics ; Polymorphism, Single Nucleotide/*genetics ; Stroke/geneticsPublished by: -
2Shields, R. K., Nguyen, M. H., Chen, L., Press, E. G., Kreiswirth, B. N., Clancy, C. J.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-04-27Publisher: The American Society for Microbiology (ASM)Print ISSN: 0066-4804Electronic ISSN: 1098-6596Topics: BiologyMedicinePublished by: -
3Moskowitz, C. H., Walewski, J., Nademanee, A., Masszi, T., Agura, E., Holowiecki, J., Abidi, M. H., Chen, A. I., Stiff, P., Viviani, S., Bachanova, V., Sureda, A., McClendon, T., Lee, C., Lisano, J., Sweetenham, J.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-12-21Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Lymphoid Neoplasia, Brief Reports, Clinical Trials and ObservationsPublished by: -
4Y. Sztainberg ; H. M. Chen ; J. W. Swann ; S. Hao ; B. Tang ; Z. Wu ; J. Tang ; Y. W. Wan ; Z. Liu ; F. Rigo ; H. Y. Zoghbi
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-11-26Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Attachment Sites, Microbiological/genetics ; Cells, Cultured ; Disease Models, Animal ; Electroencephalography ; Gene Dosage/*genetics ; Gene Duplication/genetics ; *Gene Knockdown Techniques ; Genes, Duplicate/*genetics ; Humans ; Integrases/genetics/metabolism ; Mental Retardation, X-Linked/*genetics/physiopathology ; Methyl-CpG-Binding Protein 2/*genetics/metabolism ; Mice ; Mice, Transgenic ; Oligonucleotides, Antisense/*genetics ; *PhenotypePublished by: -
5N. Rhind ; Z. Chen ; M. Yassour ; D. A. Thompson ; B. J. Haas ; N. Habib ; I. Wapinski ; S. Roy ; M. F. Lin ; D. I. Heiman ; S. K. Young ; K. Furuya ; Y. Guo ; A. Pidoux ; H. M. Chen ; B. Robbertse ; J. M. Goldberg ; K. Aoki ; E. H. Bayne ; A. M. Berlin ; C. A. Desjardins ; E. Dobbs ; L. Dukaj ; L. Fan ; M. G. FitzGerald ; C. French ; S. Gujja ; K. Hansen ; D. Keifenheim ; J. Z. Levin ; R. A. Mosher ; C. A. Muller ; J. Pfiffner ; M. Priest ; C. Russ ; A. Smialowska ; P. Swoboda ; S. M. Sykes ; M. Vaughn ; S. Vengrova ; R. Yoder ; Q. Zeng ; R. Allshire ; D. Baulcombe ; B. W. Birren ; W. Brown ; K. Ekwall ; M. Kellis ; J. Leatherwood ; H. Levin ; H. Margalit ; R. Martienssen ; C. A. Nieduszynski ; J. W. Spatafora ; N. Friedman ; J. Z. Dalgaard ; P. Baumann ; H. Niki ; A. Regev ; C. Nusbaum
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-04-23Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Centromere/genetics/physiology/ultrastructure ; DNA Transposable Elements ; Evolution, Molecular ; Gene Expression Profiling ; Gene Expression Regulation, Fungal ; Genes, Mating Type, Fungal ; *Genome, Fungal ; Genomics ; Glucose/metabolism ; Meiosis ; Molecular Sequence Annotation ; Molecular Sequence Data ; Phylogeny ; RNA, Antisense/genetics ; RNA, Fungal/genetics ; RNA, Small Interfering/genetics ; RNA, Untranslated/genetics ; Regulatory Elements, Transcriptional ; Schizosaccharomyces/*genetics/growth & development/metabolism ; Schizosaccharomyces pombe Proteins/genetics/metabolism ; Sequence Analysis, DNA ; Species Specificity ; Transcription Factors/genetics/metabolism ; Transcription, GeneticPublished by: -
6J. L. Morgan ; J. T. McNamara ; M. Fischer ; J. Rich ; H. M. Chen ; S. G. Withers ; J. Zimmer
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-03-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Cellulose/*biosynthesis/chemistry/*metabolism ; Crystallography, X-Ray ; Glucose/metabolism ; Glucosyltransferases/*chemistry/*metabolism ; Intracellular Membranes/chemistry/*metabolism ; Models, Molecular ; Movement ; Protein Structure, Secondary ; Proteolipids/chemistry/metabolism ; Rhodobacter sphaeroides/enzymology ; Substrate SpecificityPublished by: -
7J. H. Kim ; R. Resende ; T. Wennekes ; H. M. Chen ; N. Bance ; S. Buchini ; A. G. Watts ; P. Pilling ; V. A. Streltsov ; M. Petric ; R. Liggins ; S. Barrett ; J. L. McKimm-Breschkin ; M. Niikura ; S. G. Withers
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-02-23Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antiviral Agents/*chemistry/pharmacology ; Crystallography, X-Ray ; Dogs ; Enzyme Inhibitors/*chemistry/pharmacology ; Humans ; Madin Darby Canine Kidney Cells ; Neuraminidase/*antagonists & inhibitors/chemistry ; Orthomyxoviridae/*drug effects/enzymology ; Oseltamivir/chemistry/pharmacology ; Protein Conformation ; Sialic Acids/*chemistry/pharmacology ; Structure-Activity Relationship ; Zanamivir/chemistry/pharmacologyPublished by: -
8H. T. Hsu ; H. M. Chen ; Z. Yang ; J. Wang ; N. K. Lee ; A. Burger ; K. Zaret ; T. Liu ; E. Levine ; S. E. Mango
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-06-20Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Caenorhabditis elegans/*embryology/genetics/metabolism ; Caenorhabditis elegans Proteins/*metabolism ; Chromatin/*metabolism ; *Gene Expression Regulation, Developmental ; Genes, Helminth ; RNA Polymerase II/*metabolism ; Trans-Activators/*metabolism ; Transcription Initiation Site ; TranscriptomePublished by: -
9Tak, W. Y., Lin, S.-M., Wang, Y., Zheng, J., Vecchione, A., Park, S. Y., Chen, M. H., Wong, S., Xu, R., Peng, C.-Y., Chiou, Y.-Y., Huang, G.-T., Cai, J., Abdullah, B. J. J., Lee, J. S., Lee, J. Y., Choi, J.-Y., Gopez-Cervantes, J., Sherman, M., Finn, R. S., Omata, M., O'Neal, M., Makris, L., Borys, N., Poon, R., Lencioni, R.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-01-04Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
10J J Liang, J H Yu, J Chen, M H Qin, M Zeng, X B Lu, X S Gao and J–M Liu
Institute of Physics (IOP)
Published 2018Staff ViewPublication Date: 2018-05-16Publisher: Institute of Physics (IOP)Electronic ISSN: 1367-2630Topics: PhysicsPublished by: -
11Ma, Y.-N., Xu, D.-B., Li, L., Zhang, F., Fu, X.-Q., Shen, Q., Lyu, X.-Y., Wu, Z.-K., Pan, Q.-F., Shi, P., Hao, X.-L., Yan, T.-X., Chen, M.-H., Liu, P., He, Q., Xie, L.-H., Zhong, Y.-J., Tang, Y.-L., Zhao, J.-Y., Zhang, L.-D., Sun, X.-F., Tang, K.-X.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-11-15Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
12WU, J. L. ; CHOU, C. C. ; CHEN, M. H. ; WU, C. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1750-3841Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Approximately 0.030%, 0.012% and 0.005% (v/w), in wet weight, of volatile oils were obtained from raw, baked and deep-fried shallots, respectively. These oils have been studied by a gas chromatograph coupled to a mass spectrometer. The flavor components of these oils can be classified in the following categories: thiols, monosulfides, disulfides, trisulfides, thiophenes and oxygen compounds. After heating (baking or deep-frying) of the shallot, a sharp increase in the amount of dimethylthiophenes was observed and the alkyl propenyl disulfides decreased.Type of Medium: Electronic ResourceURL: -
13Wang, K. ; Hiruki, C. ; Chen, M. H.
Oxford, U.K. and Cambridge, USA : Blackwell Publishers
Published 1998Staff ViewISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Monarda yellows occurring in southern Alberta was found to be associated with a phytoplasma. Using two pairs of universal primers, 16S ribosomal DNA fragments (about 1.5 and 1.2 kb) were amplified separately by polymerase chain reaction (PCR) from DNA samples that had been extracted from infected monarda. No such DNA bands were observed using DNA samples from uninfected monarda. The DNA fragment (1.2 kb) amplified by nested-PCR was analysed and compared with western aster yellows (AY27, Canada), eastern aster yellows (EAY, USA), French hydrangea aster yellows (AYHF), Belgium hydrangea aster yellows (AYHB), clover proliferation (CP, Canada) and potato witches'-broom (PWB, Canada) by means of restriction fragment length polymorphism (RFLP) using endonucleases AluI, MseI, HpaII, Sau3AI, KpnI and RsaI. The results showed that monarda yellows phytoplasma belongs to the aster yellows subclade and is different from CP and PWB. This is the first report of aster yellows phytoplasma infecting monarda.Type of Medium: Electronic ResourceURL: -
14Tse, G M K ; Ma, T K F ; Chan, K-F ; Law, B K B ; Chen, M-H ; Li, K-H ; Chan, E C K ; Mak, M K F
Oxford UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Increased microvessel density in malignant and borderline mammary phyllodes tumours Aims: Tumour vascularity is considered a prognostic indicator in breast carcinoma, but its utility in mammary phyllodes tumour has not been explored. The authors report the correlation between intratumoral microvessel density and the histological grade of phyllodes tumour. Methods and results: Forty cases of phyllodes tumour were reviewed for stromal cellularity, overgrowth, cytological pleomorphism, mitotic count and margin pattern. Using established criteria, these were diagnosed as benign (n=28), borderline (n=10) and malignant (n=2). Microvessel density was counted on CD31-stained slides as the number of vessels per high power field. For benign phyllodes tumour, the range was 7–26.2 (mean 13.1); for borderline phyllodes tumour the range was 17.2–32.5 (mean 22.4); for malignant phyllodes tumour the range was 25.9–33.3 (mean 29.6). The difference between the benign and borderline groups was significant (P 〈 0.0001) but that between the borderline and malignant groups was not, due to the small number of malignant cases. Conclusions: There is a significant difference in stromal microvessel density between benign and borderline phyllodes tumour. Although the small number of cases of malignant phyllodes tumour limits further interpretation, we believe that microvessel density can be used as an additional objective histological parameter in the evaluation of phyllodes tumour.Type of Medium: Electronic ResourceURL: -
15Wong, W. M. ; Xiao, S. D. ; Hu, P. J. ; Wang, W. H. ; Gu, Q. ; Huang, J. Q. ; Xia, H. H.-X. ; Wu, S. M. ; Li, C. J. ; Chen, M. H. ; Cui, Y. ; Lai, K. C. ; Hu, W. H. C. ; Chan, C. K. ; Lam, S. K. ; Wong, B. C.-Y.
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background : Recent studies suggest that the Helicobacter pylori eradication rate in patients with non-ulcer dyspepsia is lower when compared to patients with peptic ulcer diseases.Aim : The aim of this study was to study the efficacy of triple therapy for H. pylori infection in patients with duodenal ulcer vs. patients with non-ulcer dyspepsia.Methods : A total of 582 Chinese patients with proven H. pylori infection were recruited to receive: omeprazole 20 mg, amoxicillin 1000 mg and clarithromycin 500 mg all given twice daily for 7 days (OCA regime). Endoscopy with rapid urease test, histology and culture were performed before treatment. Post-treatment H. pylori status was determined by 13C-urea breath test. Metronidazole, clarithromycin and amoxicillin resistance was defined as minimum inhibitory concentration (MIC) of 〉8 μg/mL, 〉1 μg/mL and 〉1 μg/mL, respectively.Results : A significantly higher (intention-to-treat/per-protocol) eradication rate was found in patients with duodenal ulcer than those with non-ulcer dyspepsia (91/94% vs. 84/88% respectively, P = 0.011 and P = 0.016). Clarithromycin resistance rate was higher in patients with non-ulcer dyspepsia than those with duodenal ulcer (14% vs. 6%, P = 0.015). Clarithromycin resistance (40% vs. 5%, P 〈 0.001, OR 12, 95% CI: 5.7–24.3) and the diagnosis of non-ulcer dyspepsia (91% vs. 84%, P = 0.011, OR 2.0, 95% CI: 1.2–3.3) significantly affected the success of H. pylori eradication.Conclusion : Clarithromycin resistance accounts for the significantly lower and suboptimal H. pylori eradication rate of OCA regimen in Chinese patients with non-ulcer dyspepsia compared to those with duodenal ulcer.Type of Medium: Electronic ResourceURL: -
16Xiong, L. S. ; Chen, M. H. ; Chen, H. X. ; Xu, A. G. ; Wang, W. A. ; Hu, P. J.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background : The detailed population-based data on irritable bowel syndrome in South China are lacking.Aims : To assess the prevalence of irritable bowel syndrome in South China and its impact on health-related quality of life.Subjects and methods : A face-to-face interview was carried out in South China to assess the prevalence of irritable bowel syndrome. Random clustered sampling of permanent inhabitants aged 18–80 years was carried out under stratification of urban and suburban areas. The impact of irritable bowel syndrome on health-related quality of life was evaluated using the Chinese version of SF-36.Results : A total of 4178 subjects (1907 male and 2271 female) were interviewed. The adjusted prevalence of irritable bowel syndrome in South China is 11.50% according to the Manning criteria and 5.67% according to the Rome II criteria. Factors including history of analgesic use such as non-steroidal anti-inflammatory drug (odds ratio 3.83), history of food allergies (odds ratio 2.68), psychological distress (odds ratio 2.18), life events (odds ratio 1.89), history of dysentery (odds ratio 1.63) and negative coping style (odds ratio 1.28) were significantly associated with the presence of irritable bowel syndrome (P 〈 0.05). Irritable bowel syndrome was significantly associated with a decrement in health-related quality of life score.Conclusion : Irritable bowel syndrome is a common disorder in South China and has a negative impact on health-related quality of life.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0021-9991Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Computer SciencePhysicsType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
19Kulneff-Herlin, A. ; Herlin, P. ; Chen, M.-H. ; Gimmon, Z. ; Murphy, R.F. ; Joffe, S.N.
Amsterdam : ElsevierStaff ViewISSN: 0196-9781Keywords: Gastrin ; Glucagon ; Immunoreactivities ; Jejuno-ileal bypass ; VIPSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: