Search Results - (Author, Cooperation:M. H. Chang)

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  1. 1
    Hong, S. Y., Park, Y., Hwang, Y., Kim, Y. B., Baik, M.-H., Chang, S.
    American Association for the Advancement of Science (AAAS)
    Published 2018
    Staff View
    Publication Date:
    2018-03-06
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Chemistry
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-05-26
    Publisher:
    The American Society for Microbiology (ASM)
    Print ISSN:
    0066-4804
    Electronic ISSN:
    1098-6596
    Topics:
    Biology
    Medicine
    Published by:
    http://www.asm.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-08-11
    Publisher:
    The American Society for Pharmacology and Experimental Therapeutics
    Print ISSN:
    0022-3565
    Electronic ISSN:
    1521-0103
    Topics:
    Medicine
    Published by:
    http://www.aspet.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2015-11-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2015-05-08
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    H. M. Chang ; R. Triboulet ; J. E. Thornton ; R. I. Gregory
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-04-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cells, Cultured ; Embryonic Stem Cells/metabolism ; Exonucleases/*metabolism ; Exoribonucleases/*metabolism ; Fetal Macrosomia/*enzymology/*genetics/metabolism ; HEK293 Cells ; Humans ; Mice ; MicroRNAs/genetics/*metabolism ; RNA Precursors/genetics/metabolism ; RNA Processing, Post-Transcriptional ; *RNA Stability ; RNA-Binding Proteins/*metabolism ; Ribonucleases/*metabolism ; Substrate Specificity ; Uridine Monophosphate/analogs & derivatives/metabolism ; Wilms Tumor/*enzymology/etiology/*genetics/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Chang, M.-H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-7187
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Economics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-7187(91)90023-E

    Articles: DFG German National Licenses
  8. 8
    Wong, Y. -C. ; Li, Y. -W. ; Chang, M. -H.
    Springer
    Published 1994
    Staff View
    ISSN:
    1432-1998
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Blue rubber bleb nevus syndrome (BRBNS), which consists of cutaneous and visceral hemangiomas, is a rare disease. Complications such as gastrointestinal (GI) bleeding, anemia and coagulopathy have been documented. We report a patient with BRBNS who presented with acute paraparesis in addition to GI bleeding and coagulopathy.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02012746

    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    1432-1076
    Keywords:
    Asplenia syndrome ; Hiatus hernia ; Magnetic resonance imaging
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract During a 13-month period, 13 patients with asplenia syndrome were evaluated with MRI for cardiovascular and visceral anomalies. The MR images were reviewed for the presence of hiatus hernia which was found in three patients. One of the remaining ten patients with no MRI evidence of hiatus hernia was diagnosed as having gastro-oesophageal reflux and hiatus hernia by an oesophagogram and 24-h pH monitoring. This patient had undergone fundoplication prior to MRI. Out of the 13 patients (31%) with asplenia syndrome, 4 had hiatus hernia. It appears that among patients with the asplenia syndrome, hiatus hernia is a frequent finding. Recurrent pneumonia or bronchiolitis in patients with asplenia syndrome requires evaluation for the presence of hiatus hernia and gastro-oesophageal reflux.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01955901

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1432-1076
    Keywords:
    Necrotizing bowel lesions ; Pseudomonas septicaemia ; Healthy infants
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Two previously healthy infants withPseudomonas septicaemia presented with necrotizing bowel lesions. Necrotizing bowel lesions should be suspected when infants presenting with a history of diarrhoea, develop abdominal distension and toxic signs.Pseudomonas aeruginosa should be regarded as one of the important aetiologies in such disorders, especially if there is associated neutropenia and ecthyma gangrenosum-like lesions. Antibiotics must be able to cover this pathogen to avert a catastrophic outcome. Conclusion The intestine should be considered a possible site of involvement inPseudomonas sepsis and special attention should be paid to examination of the abdomen.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01953941

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    1432-0711
    Keywords:
    Key words: Hepatitis B virus – Genetic amniocentesis – Intrauterine infection
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract. Sixty-seven pairs of mothers with hepatitis B virus (HBV) surface antigen (HBsAg) and their infants were divided into two study groups to determine the effect of amniocentesis on intrauterine HBV infection. In the first study group (35 pairs), the infant's HBsAg status in cord blood was studied and the results were compared with those obtained in the cord blood from 65 infants born to HBsAg-positive women who did not have an amniocentesis. In the second study group (32 pairs), the HBV status of the infants was studied at the age of three months to five years and compared with the HBV status of 3,454 infants in the National HBV Prevention Program. In the first study group, one sample (2.9%) was weakly positive for HBsAg; while in the first control group, two (3.1%) were positive. In the second study group, three (10%) infants were positive for HBsAg. The failure rates of immunoprophylaxis in the second study and control groups were similar (9.4% vs 11% for HBsAg carrier mothers; 30% vs 14% for HBe antigen-positive carrier mothers). This suggested that genetic amniocentesis did not increase the risk of intrauterine HBV infection.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004040050021

    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    1432-0711
    Keywords:
    Hepatitis B virus ; Genetic amniocentesis ; Intrauterine infection
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Sixty-seven pairs of mothers with hepatitis B virus (HBV) surface antigen (HBsAg) and their infants were divided into two study groups to determine the effect of amniocentesis on intrauterine HBV infection. In the first study group (35 pairs), the infant's HBsAg status in cord blood was studied and the results were compared with those obtained in the cord blood from 65 infants born to HBsAg-positive women who did not have an amniocentesis. In the second study group (32 pairs), the HBV status of the infants was studied at the age of three months to five years and compared with the HBV status of 3,454 infants in the National HBV Prevention Program. In the first study group, one sample (2.9%) was weakly positive for HBsAg; while in the first control group, two (3.1%) were positive. In the second study group, three (10%) infants were positive for HBsAg. The failure rates of immunoprophylaxis in the second study and control groups were similar (9.4% vs 11% for HBsAg carrier mothers; 30% vs 14% for HBe antigen-positive carrier mothers). This suggested that genetic amniocentesis did not increase the risk of intrauterine HBV infection.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02390671

    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    1573-2665
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1005651809892

    Articles: DFG German National Licenses
  14. 14
    Chang, M.-H. ; Lin, H.-C. ; Hwang, P.P.
    Springer
    Published 1997
    Staff View
    ISSN:
    1573-5168
    Keywords:
    tilapia ; larvae ; toxicity ; development ; cadmium ; calcium ; Ca2+ influx ; Km ; Vmax
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract The toxic effects of Cd2+ on Ca2+ influx kinetics in developing tilapia (Oreochromis mossambicus) larvae were evaluated. Addition of 20 µg l-1 of Cd2+ to the environment of 0 and 3 day-old larvae competitively inhibited the Ca2+ uptake within 4h resulting in a great increase in Km values for Ca2+ influx (19.3 and 17.4 fold, respectively) as compared with their respective controls. Consequently, the actual Ca2+ influx of larvae in solutions of 0.2 mM Ca2+ are suppressed by 32–45%. Also, 3 day-old larvae were more sensitive to internally accumulated Cd2+ than 0 day-old larvae. Although the Ca2+ influx in 0 and 3 day-old larvae may be restored to the levels of their respective controls with 24h of being transferred to a 20 µg l-1 Cd2+ solution, total body Ca2+ content was significantly reduced in 3 day-old larvae. Increased Ca2+ uptake efficiency ensures sufficient Ca2+ for normal growth. However, rapid increase in Ca2+ influx after hatching also leads to higher Cd2+ uptake. Exposure to Cd2+ will lead to a drop in body Ca2+ content resulting in retardation of larval growth. Therefore, we conclude that if Ca2+ uptake is interfered with at this critical stage of development, larvae will not be able to maintain normal levels of body Ca2+ and will show signs of Cd2+ poisoning.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1007780602426

    Articles: DFG German National Licenses
  15. 15
    Chang, M. H. ; Liu, P. T.
    Springer
    Published 1975
    Staff View
    ISSN:
    1573-2878
    Keywords:
    Control theory ; maximum principle ; functional differential equations ; optimization theorems
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mathematics
    Notes:
    Abstract Three optimal control problems involving measure functional differential equations are considered. The necessary conditions, in the form of the Pontryagin maximum principle, for an optimal control are obtained. This is accomplished by the application of a theorem by Debovistskii-Milyutin. A simple example is also illustrated to show the applicability of the results obtained.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00933743

    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    1435-232X
    Keywords:
    Key words Glycogen storage disease type Ia ; Glucose-6-phosphatase ; Mutation ; Chinese ; Taiwan
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract Glycogen storage disease type Ia (GSD Ia) is caused by a deficiency of glucose-6-phosphatase (G6Pase) activity. Eighteen GSD Ia families were studied for G6Pase gene mutations. Thirty-two mutations were found in 36 GSD Ia chromosomes: 16 were 727 G→T (44.44%); 13 were R83H (327 G→T; 36.11%); 1 was 341delG; 1 was 933insAA; and 1 was 793 G→T. The 727 G→T and R83H mutations together accounted for 80.56% (29/36) of the GSD Ia chromosomes. These two mutations were easily examined by polymerase chain reaction-based methods, and the prenatal diagnosis of a non-affected fetus was successfully made. The 727 G→T mutation is the predominant mutation in Japanese GSD Ia patients, but is rarely seen in Western counties. The 727 G→T mutation is also the most prevalent mutation in Taiwan Chinese, although the incidence is not as high as in Japan.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s100380070026

    Articles: DFG German National Licenses