Search Results - (Author, Cooperation:M. Gloor)
-
1Latest Papers from Table of Contents or Articles in PressJ. C. A. Baker, M. Gloor, A. Boom, D. A. Neill, B. B. L. Cintra, S. J. Clerici, R. J. W. Brienen
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-01-30Publisher: Wiley-BlackwellPrint ISSN: 0094-8276Electronic ISSN: 1944-8007Topics: GeosciencesPhysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressL. V. Gatti ; M. Gloor ; J. B. Miller ; C. E. Doughty ; Y. Malhi ; L. G. Domingues ; L. S. Basso ; A. Martinewski ; C. S. Correia ; V. F. Borges ; S. Freitas ; R. Braz ; L. O. Anderson ; H. Rocha ; J. Grace ; O. L. Phillips ; J. Lloyd
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-02-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Atmosphere/*chemistry ; Biomass ; Biota ; Brazil ; *Carbon Cycle ; Carbon Dioxide/analysis ; Carbon Monoxide/analysis ; Droughts/*statistics & numerical data ; Fires/statistics & numerical data ; Fresh Water/analysis ; Photosynthesis ; Rain ; Seasons ; Trees/metabolism ; Tropical ClimatePublished by: -
3Latest Papers from Table of Contents or Articles in PressWartenberg, M., Cibin, S., Zlobec, I., Vassella, E., Eppenberger-Castori, S., Terracciano, L., Eichmann, M. D., Worni, M., Gloor, B., Perren, A., Karamitopoulou, E.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-09-15Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
4Latest Papers from Table of Contents or Articles in PressS. Houweling ; B. Badawy ; D. F. Baker ; S. Basu ; D. Belikov ; P. Bergamaschi ; P. Bousquet ; G. Broquet ; T. Butler ; J. G. Canadell ; J. Chen ; F. Chevallier ; P. Ciais ; G. J. Collatz ; S. Denning ; R. Engelen ; I. G. Enting ; M. L. Fischer ; A. Fraser ; C. Gerbig ; M. Gloor ; A. R. Jacobson ; D. B. Jones ; M. Heimann ; A. Khalil ; T. Kaminski ; P. S. Kasibhatla ; N. Y. Krakauer ; M. Krol ; T. Maki ; S. Maksyutov ; A. Manning ; A. Meesters ; J. B. Miller ; P. I. Palmer ; P. Patra ; W. Peters ; P. Peylin ; Z. Poussi ; M. J. Prather ; J. T. Randerson ; T. Rockmann ; C. Rodenbeck ; J. L. Sarmiento ; D. S. Schimel ; M. Scholze ; A. Schuh ; P. Suntharalingam ; T. Takahashi ; J. Turnbull ; L. Yurganov ; A. Vermeulen
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-09-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Atmosphere/*chemistry ; Carbon Dioxide/*analysis ; *Climate ChangePublished by: -
5Articles: DFG German National LicensesStaff View
ISSN: 1468-2494Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The influence of a liposomal formulation of a ceramide/phospholipid mixture on the barrier function of the skin in atopic tests, in subjects with healthy skin, and after lipid extraction was tested. The transepidermal water loss and the stratum corneum hydration served as parameters for the evaluation of the influence of the ceramide/phospholipid-mixture treatment on the barrier function. Additionally a barrier-function test with nicotinic acid ester was performed after ceramide/phospholipid-mixture application. Stabilizing effects on the barrier function after application of ceramide/phospholipid-mixture were found only in atopic skin and after lipid extraction but not in healthy skin. The results lead us to expect positive effects of ceramide/phospholipid-mixture only if barrier damage is present. On a teste l'influence d'une formulation aux liposomes d'un melange ceramide/phospholipide sur la fonction protectrice de la peau de personnes lors d'un test atopique, sur une peau saine, et apres extraction lipidique. On a utilise la perte d'eau transepidermique et l'hydratation de la couche cornee comme parametres d'evaluation de l'influence du traitement sur la fonction protectrice. On a en outre effectue apres application un test de la fonction protectrice avec un ester d'acide nicotinique. On a constate des effets stabilisateurs de la fonction protectrice apres application seulement sur peau atopique et apres extraction lipidique mais pas sur peau saine. Les resultats nous conduisent a esperer des effets positifs uniquement en cas d'alteration de la fonction protectrice de la peau.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesGrunewald, A. M. ; Gloor, M. ; Gehring, W. ; Kleesz, P.
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1600-0536Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Damage to the skin following the repeated use of 2 different wash solutions was investigated. Stratum corneum capacitative resistance, stratum corneum lipids, transepidermal water loss, skin surface pH, laser Doppler flow and skin reddening were determined. All skin function parameters already showed a marked change after a single wash (e.g., the median of TEWL values increased by more than 0.5 g/m2 h). Repetitive washing for 1 week led to a further deterioration of TEWL and corneometry values (e.g., TEWL increased for about 2.9 g/m2 h after repetitive washing with sodium lauryl sulfate). The rate of skin function regeneration after repetitive washing was unaltered compared to regeneration after a single wash. The surfactants used showed quantitatively differing effects on corneometry, TEWL and laser Doppler flow (e.g., after repetitive washing with Geli-derm, the median of TEWL values increased only up to 1.55 g/m2 h). However, damage arising from repetitive washing could not be completely prevented by the selection of a mild surfactant. Skin function regeneration showed no difference with the 2 surfactants used.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1600-0536Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1600-0536Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: It was the aim of our studies to estimate predictively the individual eczema risk for persons due to repetitive contact with washing-active substances, by a barrier function test on clinically healthy skin over 2 weeks. Within the scope of the study 3 groups with different atopy scores were compared. As washing solutions, 0.1m SLS and a slightly acid soap-free washing emulsion were used in comparison to tap water. Prior to the 1st washing procedure, on days 3, 5, 8, 10, and 12, the transepidermal water loss, the horny layer moisture, and the skin blood flow were measured as parameters of barrier function, as well as the inflammatory reaction. The results prove that the atopy score has only limited validity as a predictive method for the acceptance of washing-active substances. The repetitive washing test, however, seems to be more adequate for evaluating the individual barrier function as well as the eczema risk. Irritation by a washing procedure may be greatly influenced by choice of the washing solution.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesBettinger, J. ; Gloor, M. ; Vollert, A. ; Kleesz, P. ; Fluhr, J. ; Gehring, W.
Oxford, UK : Blackwell Publishing Ltd
Published 1999Staff ViewISSN: 1600-0846Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: In dermatology and cosmetics, moisturizers are used to soften skin. The objectives of this study were to compare the influence of three different moisturizers on skin hydration and skin mechanics by various non-invasive test methods and to determine the relationship between the methods used.〈section xml:id="abs1-2"〉〈title type="main"〉Methods:In 27 test subjects, four test areas in each were treated over 3 days, three times a day. An oil-in-water (o/w) emulsion was applied without moisturizer, the same with 10% glycerol, with 10% urea, or with 10% propylene glycol, respectively. Three hours after the last treatment results were measured by using the following instruments: Corneometer CM 820, Skicon 200, Frictionmeter, and Cutometer.〈section xml:id="abs1-3"〉〈title type="main"〉Results/Conclusions:In all procedures a significant effect, in the sense of an increase in the data recorded, could be demonstrated by glycerol-treatment. During Corneometer, Frictionmeter, and Cutometer measurements, an additional unidirectional effect caused by the basic emulsion was seen. With all test methods, the influence of urea and propylene glycol was not significant compared to the basic emulsion. For all pretreatments there was a correlation between Corneometer data and Skicon data. Because of the low correlation coefficients between hydration parameters and mechanical parameters, it is to be assumed that other effects of glycerol- and basic-emulsion-treatment-independent from the hydration effect – have an additional influence on the data obtained by using the Frictionmeter and the Cutometer. This indicates that the clinical effect of emulsions should not be evaluated exclusively on the basis of electrical measurements of hydration.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesFluhr, J.W. ; Kuss, O. ; Diepgen, T. ; Lazzerini, S. ; Pelosi, A. ; Gloor, M. ; Berardesca, E.
Oxford, UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background Non-invasive bioengineering methods are widely used in the assessment of irritant skin reactions. Objectives To assess the ability of eight non-invasive measurement techniques to distinguish changes in skin conditions over time, these changes being induced by five different irritants. Methods The following techniques were compared in a multivariate analysis: laser-Doppler perfusion imaging (LDI), laser-Doppler flowmetry (LDF), transepidermal water loss (TEWL), visual scoring (VS), colorimetric measurements (Chromameter CR 200 a* and L* scales), Mexameter Hb scale (Mexa Hb) and capacitance (Corneometer CM 820). Irritants tested were sodium lauryl sulphate 2% (SLS), tape stripping (TS), tretinoin 0·05% (TRET), ultraviolet (UV) exposure to 30 W m−2 UVB/95 W m−2 UVA, and dithranol 0·5% (DIT). Measurements were performed at baseline and after 24, 48 and 72 h. The study was conducted on the upper back of 11 healthy volunteers of both sexes aged 27–51 years. Results For DIT it was possible to discriminate over time with CR 200 a* and L*, VS, LDI, LDF and Mexa Hb. In SLS discrimination over time was seen with TEWL and LDF. Discrimination in TS was demonstrated for TEWL, VS, CR 200 a*, CM 820, LDF, LDI and Mexa Hb. In TRET discrimination ability was seen for LDI, LDF, Mexa Hb and VS. For UV it was possible to discriminate using VS, TEWL, LDF, LDI and Mexa Hb. Conclusions Different irritation patterns need different measurement modalities in order to give optimal discrimination over time.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0006-291XKeywords: [abr] EDTA; Ethylendiamine-tetrancetic acid ; [abr] EGTA; Ethyleneglycol-bis-(amino-ethylether) N,N,-tetraacetic acid ; [abr] Hepes; N-2-Hydroxyethylpiperazine-N-2-ethane-sulfonicacid ; [abr] PMSF; Phenylmethylsulfonyl fluoride ; [abr] SDS; sodium dodecylsulfateSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0006-291XKeywords: [abr] EDTA; Ethylendiamine-tetrancetic acid ; [abr] EGTA; Ethyleneglycol-bis-(amino-ethylether) N,N,-tetraacetic acid ; [abr] Hepes; N-2-Hydroxyethylpiperazine-N-2-ethane-sulfonicacid ; [abr] PMSF; Phenylmethylsulfonyl fluoride ; [abr] SDS; sodium dodecylsulfateSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1432-069XSource: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Zusammenfassung Bei Acnekranken wird eine signifikante Erhöhung des Lipidspiegels der Haut und ein signifikant schnellerer Ersatz der Hautoberflächenlipide nach Entfetten der Haut nachgewiesen. Die Seborrhoe ist dabei um so ausgeprägter, je schwerer das klinische Krankheitsbild ist. Mikrodünnschichtchromatographische Untersuchungen zeigen, daß bei Acnekranken die Triglycerid- und Squalenfraktion signifikant erhöht und die Cholesterin- und Paraffinfraktion signifikant erniedrigt sind gegenüber gesunden Vergleichspersonen. Auch diese Veränderungen sind um so ausgeprägter, je schwerer das klinische Krankheitsbild ist. Bei schweren Formen ist zusätzlich eine signifikante Verminderung der Fraktion der freien Fettsäuren nachweisbar. Eine Vermehrung der freien Fettsäuren und Wachsester auf Kosten der Triglyceride, die beim Seborrhoiker zu erwarten ist, war bei Acnekranken nicht nachweisbar.Notes: Summary In acne patients a significant increase of the lipid level and a quicker replacement of the skin surface lipids after defatting the skin is demonstrated. The more serious the clinical picture is, the more pronounced is the seborrhoea. Microthinlayer chromatographic investigations show, that in acne patients the triglycerid and squalen fractions are increased, while the cholesterol and paraffin fractions are decreased, compared with those of healthy persons. These changes are more pronounced in the more serious forms of the disease. In addition, there is also a significant decrease of the free fatty acid fraction in the serious forms. An increase of free fatty acids and wax esters, which was expectable because of seborrhoea, was not to be found in patients suffering from acne vulgaris.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1432-069XSource: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Zusammenfassung Bei 25 Acnekranken wurden vor und nach einer 8 wöchigen Tetracyclintherapie die Menge der Hautoberflächenlipide und die nach Entfetten in 2 Std ersetzte Lipidmenge bestimmt. Außerdem wurden die Hautoberflächenlipide jeweils dünnschichtchromatographisch analysiert. 13 Patienten erhielten 8 Tage lang 1 g Oxytetracyclin täglich und dann 7 Wochen lang 100 mg Oxytetracyclin täglich; die restlichen 12 Patienten erhielten 8 Wochen lang täglich 1 g Oxytetracyclin. Während die Quantität der Hautoberflächenlipide unbeeinflußt blieb, kam es bei der höheren Dosierung zu einer signifikanten Verminderung des Anteils der freien Fettsäuren, der Wachsester und des Cholesterin an den Hautoberflächenlipiden zugunsten der Triglyceride. Bezüglich der freien Fettsäuren und der Triglyceride fanden sich bei der niedereren Dosierung die gleichen Verhältnisse.Notes: Summary Quantitative determination of the skin surface lipids was carried out in 25 patients with acne before and after treatment with tetracycline for 8 weeks. Determinations were performed immedeately and 2 h after defatting the skin surface. In addition, the lipids were analysed by thin-layer-chromatography. 13 patients received 1 g oxytetracycline per day for 8 days which was followed by a daily administration of 100 mg oxytetracycline for 7 weeks. In 12 patients 1 g oxytetracycline was administrated daily for 8 weeks. Quantitatively there was no change in the amount of skin surface lipids recovered. The group of patients treated with higher dosage tetracycline showed significant reduction of free fatty-acids, wax esters and cholesterol, while the amount of triglycerides was elevated. This free fatty acids-triglyceride relation was also observed in the group of patients treated with low dosage tetracycline.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1432-069XSource: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Zusammenfassung Parallele Untersuchungen mit dem Osmiumsäuretest und qualitative und quantitative Bestimmungen der Hautoberflächenlipide an 51 Versuchspersonen 2 Stunden nach Entfetten der Haut mit Petroläther zeigten, daß die Reaktion der Talgdrüsen auf die Entfettung der Haut von Fall zu Fall, von Stelle zu Stelle und von Drüse zu Drüse stark unterschiedlich ist. Die Schnelligkeit und das Ausmaß des Lipidersatzes scheinen sowohl von der Zahl der sezernierenden Talgdrüsen als auch vom Ausmaß der Sekretion der Einzeldrüse abhängig zu sein. Außerdem war die Spreitfläche des Talgdrüsensekretes um so größer, je mehr Wachsester und je weniger Paraffine in den Hautoberflächenlipiden nachweisbar waren. Parallele Messungen der Benetzbarkeit der Haut mit Wasser und Paraffinöl sowie quantitative und qualitative Bestimmungen der Hautoberflächenlipide vor und 2 Stunden nach Entfetten der Haut mit Petroläther machten deutlich, daß die Benetzbarkeit der Haut mit hydrophilen und lipophilen Substanzen um so besser ist, je mehr Hautoberflächenlipide vorhanden sind. Darüber hinaus nimmt die Benetzbarkeit der Haut mit steigendem Gehalt der Hautoberflächenlipide an freien Fettsäuren und sinkenden Gehalt an Paraffinen zu, während ein großer Anteil an squalen und gesättigten Kohlenwasserstoffen zu einer Begünstigung der Benetzbarkeit der Haut mit Paraffinöl führt.Notes: Summary Using the osmium acid test and qualitative and quantitative determinations of the skin surface lipids in 51 test persons 2 h after defatting the skin with petrol ether it could be shown that the reaction of the sebaceous glands to defatting of the skin differs from case to case, from body area to body area and from gland to gland. The rapidity and extent of the lipid replacement depends not only on the number of secreting sebaceous glands, but also on the extent of secretion of the single gland. The greater the surface on which sebum spreads, the more wax esters and the less paraffins can be demonstrated in the skin surface lipids. Measurements of the moistening capacity of the skin with water and paraffin oil show that the moistening capacity of the skin with hydrophilic and lipophilic substances is better when more skin surface lipids are present. Furthermore the moistening capacity of the skin increases as the content of free fatty acids in the skin surface lipids increases and as the content of paraffins decreases. A large part of squalene and saturated hydrocarbons increases the moistening capacity of the skin with paraffin oil.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1432-069XKeywords: Acne vulgaris ; Quaternary ammonium compounds ; P. acnes ; Propionibacteria ; Pilosebaceous duct ; quaternäre Ammoniumverbindungen ; Propionibakterien ; TalgdrüseninfundibulumSource: Springer Online Journal Archives 1860-2000Topics: MedicineDescription / Table of Contents: Zusammenfassung Es wird über Bestimmungen der minimalen Hemmkonzentration für verschiedene antimikrobielle Tenside unter Berücksichtigung der Keime P. acnes P. granulosum und St. epidermidis berichtet. Die Ergebnisse zeigen, daß quaternäre Ammoniumverbindungen minimale Hemmkonzentrationen aufweisen können, die denen einschlägiger Antibiotika nahezu entsprechen. Mit der besonders effektiven Substanz Dimethylkokosbenzylammoniumchlorid (ARQUAD DMMCD-B) konnte weiter gezeigt werden, daß bei in vivo Anwendung in 70% Isopropanol bzw. in einer äthanolhaltigen Filmmaskengrundlage eine Suppression von P. acnes, der Propionibakterien zusammengenommen und aller unter anaeroben Bedingungen anzüchtbarer Keime im Talgdrüseninfundibulum erzielbar ist. Die Untersuchungen könnten einen Weg zum Ersatz von Antibiotika in der antimikrobiellen Aknetherapie durch quaternäre Ammoniumverbindungen aufzeigen.Notes: Summary Determinations of the minimum inhibitory concentrations for various antimicrobial surfactants with reference to the bacteria P. acnes, P. granulosum, and St. epidermidis are reported. The results show that quaternary ammonium compounds can display minimum inhibitory concentrations corresponding to those of relevant antibiotics. With the especially effective substance fractionated dimethylcocobenzalkoniumchloride (ARQUAD DMMCD-B), it could be further shown that with in vivo application in 70% isopropanol or in an ethanol-containing film mask ointment suppression can be obtained of P. acnes, all propionibacteria added, and all pilosebaceous duct bacteria which can be cultured under anaerobic conditions. The studies may point out a way of replacing antibiotics in the antimicrobial therapy of acne by quaternary ammonium compounds.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1432-069XSource: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL:
