Search Results - (Author, Cooperation:M. G. O'Sullivan)
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1Y. Y. Tseng ; B. S. Moriarity ; W. Gong ; R. Akiyama ; A. Tiwari ; H. Kawakami ; P. Ronning ; B. Reuland ; K. Guenther ; T. C. Beadnell ; J. Essig ; G. M. Otto ; M. G. O'Sullivan ; D. A. Largaespada ; K. L. Schwertfeger ; Y. Marahrens ; Y. Kawakami ; A. Bagchi
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-07-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Transformation, Neoplastic ; Chromosomes, Human, Pair 8/genetics ; DNA Copy Number Variations/*genetics ; Disease Models, Animal ; Gene Amplification/*genetics ; Gene Dosage/*genetics ; Genes, myc/*genetics ; HCT116 Cells ; Humans ; Mice ; Mice, Inbred C57BL ; Oncogene Protein p55(v-myc)/*genetics/metabolism ; Phenotype ; RNA, Long Noncoding/*geneticsPublished by: -
2Glasby, M. A. ; Clutton, R. E. ; Drew, S. J. ; O'Sullivan, M. G. J. ; Whittle, I. R.
Springer
Published 1995Staff ViewISSN: 0942-0940Keywords: Nerve regeneration ; acoustic neuroma surgery ; muscle graft ; facial nerve ; cerebellopontine angleSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Six adult blackface sheep underwent repair of the transected facial nerve in the cerebellopontine angle using short freezethawed muscle autografts. A typical facial palsy was observed on the side of the intervention immediately after operation. The sheep were allowed to recover for one year by which time clinical observation showed a complete recovery of the facial palsy in 5 sheep and a partial recovery in the remaining sheep. Under general anaesthesia function of the repaired VIIth nerve and the normal contralateral facial nerve were assessed using electrophysiological stimulating and recording techniques. These studies showed restoration of facial nerve continuity to have taken place with functional reinnervation of target facial muscles. Electrophysiological indices of nerve function were consistent with those expected after repair of any peripheral nerve. Morphometric study of the nerves after their removal showed structural changes which though quantitatively different from those of normal nerve were consistent with those seen in other sites and studies where nerves have been repaired. This technique is discussed as a possible treatment for facial nerves whose continuity is disrupted during the removal of cerebellopontine angle tumours.Type of Medium: Electronic ResourceURL: