Search Results - (Author, Cooperation:M. G. O'Sullivan)

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  1. 1
    Staff View
    Publication Date:
    2014-07-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cell Transformation, Neoplastic ; Chromosomes, Human, Pair 8/genetics ; DNA Copy Number Variations/*genetics ; Disease Models, Animal ; Gene Amplification/*genetics ; Gene Dosage/*genetics ; Genes, myc/*genetics ; HCT116 Cells ; Humans ; Mice ; Mice, Inbred C57BL ; Oncogene Protein p55(v-myc)/*genetics/metabolism ; Phenotype ; RNA, Long Noncoding/*genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    0942-0940
    Keywords:
    Nerve regeneration ; acoustic neuroma surgery ; muscle graft ; facial nerve ; cerebellopontine angle
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Six adult blackface sheep underwent repair of the transected facial nerve in the cerebellopontine angle using short freezethawed muscle autografts. A typical facial palsy was observed on the side of the intervention immediately after operation. The sheep were allowed to recover for one year by which time clinical observation showed a complete recovery of the facial palsy in 5 sheep and a partial recovery in the remaining sheep. Under general anaesthesia function of the repaired VIIth nerve and the normal contralateral facial nerve were assessed using electrophysiological stimulating and recording techniques. These studies showed restoration of facial nerve continuity to have taken place with functional reinnervation of target facial muscles. Electrophysiological indices of nerve function were consistent with those expected after repair of any peripheral nerve. Morphometric study of the nerves after their removal showed structural changes which though quantitatively different from those of normal nerve were consistent with those seen in other sites and studies where nerves have been repaired. This technique is discussed as a possible treatment for facial nerves whose continuity is disrupted during the removal of cerebellopontine angle tumours.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01410618

    Articles: DFG German National Licenses