Search Results - (Author, Cooperation:M. Farre)
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1Michael A. Hardigan, F. Parker E. Laimbeer, John P. Hamilton, Brieanne Vaillancourt, David S. Douches, Eva M. Farre, Richard E. Veilleux, C. Robin Buell
National Academy of Sciences
Published 2018Staff ViewPublication Date: 2018-07-11Publisher: National Academy of SciencesPrint ISSN: 0027-8424Electronic ISSN: 1091-6490Topics: BiologyMedicineNatural Sciences in GeneralKeywords: LettersPublished by: -
2G. Zhang ; C. Li ; Q. Li ; B. Li ; D. M. Larkin ; C. Lee ; J. F. Storz ; A. Antunes ; M. J. Greenwold ; R. W. Meredith ; A. Odeen ; J. Cui ; Q. Zhou ; L. Xu ; H. Pan ; Z. Wang ; L. Jin ; P. Zhang ; H. Hu ; W. Yang ; J. Hu ; J. Xiao ; Z. Yang ; Y. Liu ; Q. Xie ; H. Yu ; J. Lian ; P. Wen ; F. Zhang ; H. Li ; Y. Zeng ; Z. Xiong ; S. Liu ; L. Zhou ; Z. Huang ; N. An ; J. Wang ; Q. Zheng ; Y. Xiong ; G. Wang ; B. Wang ; Y. Fan ; R. R. da Fonseca ; A. Alfaro-Nunez ; M. Schubert ; L. Orlando ; T. Mourier ; J. T. Howard ; G. Ganapathy ; A. Pfenning ; O. Whitney ; M. V. Rivas ; E. Hara ; J. Smith ; M. Farre ; J. Narayan ; G. Slavov ; M. N. Romanov ; R. Borges ; J. P. Machado ; I. Khan ; M. S. Springer ; J. Gatesy ; F. G. Hoffmann ; J. C. Opazo ; O. Hastad ; R. H. Sawyer ; H. Kim ; K. W. Kim ; H. J. Kim ; S. Cho ; N. Li ; Y. Huang ; M. W. Bruford ; X. Zhan ; A. Dixon ; M. F. Bertelsen ; E. Derryberry ; W. Warren ; R. K. Wilson ; S. Li ; D. A. Ray ; R. E. Green ; S. J. O'Brien ; D. Griffin ; W. E. Johnson ; D. Haussler ; O. A. Ryder ; E. Willerslev ; G. R. Graves ; P. Alstrom ; J. Fjeldsa ; D. P. Mindell ; S. V. Edwards ; E. L. Braun ; C. Rahbek ; D. W. Burt ; P. Houde ; Y. Zhang ; H. Yang ; E. D. Jarvis ; M. T. Gilbert
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-12-17Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptation, Physiological ; Animals ; Biodiversity ; *Biological Evolution ; Birds/classification/*genetics/physiology ; Conserved Sequence ; Diet ; *Evolution, Molecular ; Female ; Flight, Animal ; Genes ; Genetic Variation ; *Genome ; Genomics ; Male ; Molecular Sequence Annotation ; Phylogeny ; Reproduction/genetics ; Selection, Genetic ; Sequence Analysis, DNA ; Synteny ; Vision, Ocular/genetics ; Vocalization, AnimalPublished by: -
3D. A. Nusinow ; A. Helfer ; E. E. Hamilton ; J. J. King ; T. Imaizumi ; T. F. Schultz ; E. M. Farre ; S. A. Kay
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-07-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Arabidopsis/cytology/growth & development/*physiology/radiation effects ; Arabidopsis Proteins/genetics/*metabolism ; Basic Helix-Loop-Helix Transcription Factors/deficiency/genetics/metabolism ; Circadian Clocks/*physiology/radiation effects ; Circadian Rhythm/*physiology/radiation effects ; Gene Expression Regulation, Plant ; Hypocotyl/cytology/*growth & development/radiation effects ; Light ; Multiprotein Complexes/chemistry/metabolism ; Mutation ; Protein Binding ; Transcription Factors/*metabolism ; Two-Hybrid System TechniquesPublished by: -
4Sans, T. ; Joven, J. ; Vilella, E. ; Masdeu, G. ; Farrè, M.
Oxford, UK : Blackwell Publishing Ltd
Published 2000Staff ViewISSN: 1440-1681Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: 〈list xml:id="l1" style="custom"〉1The aim of the present study was to assess the effectiveness of repeated subcutaneous low-dose recombinant human erythropoietin (rHuEPO) on parameters associated with improved procurement of autologous blood; a procedure regularly used to preclude the need for homologous blood transfusion at the time of elective surgery.2Three groups of three volunteers each (n= 9) were administered one of three low doses of rHuEPO (30, 60 or 100 IU/kg body weight, s.c.) on days 1,4 and 8. The plasma pharmacokinetic profile of rHuEPO was studied after the first and third injections. Statistical evaluations were intragroup and intra-individual comparisons.3There was a linear relationship between maximum plasma concentration (Cmax) and dose. In the overall study group, Cmax and area under the curve (AUC) were significantly decreased, while the mean residence time (MRT) and elimination half-life (t1/2β) were significantly increased on day 8 relative to day 1. Significant and sustained increases in reticulocytes were observed after rHuEPO administration, which were maintained above the predose values throughout the study period.4In conclusion, rHuEPO, by subcutaneous repeat-dose, was eliminated more slowly and remained longer in the circulation, despite lowered plasma concentrations. Repeated low rHuEPO administration at doses ≥ 60 IU/kg bodyweight stimulated modest but sustained reticulocyte concentrations, suggesting that cost may be substantially decreased in autologous blood donation or perioperative treatment programmes.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 0191-8869Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1432-0606Keywords: Hyperbolic stochastic partial differential equations ; Two-parameter representable semimartingales ; Malliavin calculus ; 60H15 ; 60H07Source: Springer Online Journal Archives 1860-2000Topics: MathematicsNotes: Abstract LetW be the Wiener process onT=[0, 1]2. Consider the stochastic integral equation $$\begin{gathered} X_\zeta = x_0 + \int_{R_\zeta } {a_1 (\zeta \prime )X(s\prime ,dt\prime )ds\prime + } \int_{R_\zeta } {a_2 (\zeta \prime )X(ds\prime ,t\prime )dt\prime } \hfill \\ + \int_{R_\zeta } {a_3 (X_{\zeta \prime , } \zeta \prime )W(ds\prime ,dt\prime ) + } \int_{R_\zeta } {a_4 (X_{\zeta \prime , } \zeta \prime )ds\prime ,dt\prime ,} \hfill \\ \end{gathered} $$ whereR ζ =(s, t) ∈ T, andx 0 ∈ ℝ. Under some assumptions on the coefficients ai, the existence and uniqueness of a solution for this stochastic integral equation is already known (see [6]). In this paper we present some sufficient conditions for the law ofX ζ to have a density.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1432-2072Keywords: Flunitrazepam ; Triazolam ; Performance ; Subject ratings ; Abuse liabilitySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Flunitrazepam is an hypnotic benzodiazepine marketed in different European countries. Epidemiological studies have shown that it is frequently abused by opioid addicts. In a survey, “liking” scores for flunitrazepam in methadone maintenance patients were higher than ratings for other benzodiazepines. A double-blind, placebo controlled, crossover clinical trial was conducted to assess the acute behavioral effects of flunitrazepam (0.05 and 2 mg) and triazolam (0.25 and 0.50 mg) in healthy male volunteers. Drug effects on physiological measures, psychomotor performance, and subjective rating scales, including specific questionnaires to evaluate abuse liability (e.g., ARCI or “liking” scores), were assessed before and 6 h after drug administration. Flunitrazepam 2 mg produced the most intense disruptive effects on all the performance tasks, triazolam 0.50 impaired performance except balance. All study drugs at all doses produced sedation symptoms in all or part of the subjective effects questionnaires. Only flunitrazepam 2 mg induced significative increases in some of the scales (“liking”, “good effects”, “high”) that could be related to a possible abuse potential. The results seem to indicate that flunitrazepam, when administered to healthy subjects, produces some pleasurable subjective feelings, that could indicate a higher abuse liability of this drug as compared with other benzodiazepines.Type of Medium: Electronic ResourceURL: