Search Results - (Author, Cooperation:M. Eilers)
-
1S. C. Casey ; L. Tong ; Y. Li ; R. Do ; S. Walz ; K. N. Fitzgerald ; A. M. Gouw ; V. Baylot ; I. Gutgemann ; M. Eilers ; D. W. Felsher
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-03-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antigens, CD274/*genetics ; Antigens, CD47/*genetics ; Cell Line, Tumor ; Cell Transformation, Neoplastic/genetics/*immunology ; Down-Regulation ; *Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Immune Tolerance/*genetics ; Jurkat Cells ; Lymphoma/genetics/immunology ; Mice ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics/immunology ; Promoter Regions, Genetic ; Proto-Oncogene Proteins c-myc/genetics/*metabolism ; RNA, Small Interfering/geneticsPublished by: -
2L. Liu ; J. Ulbrich ; J. Muller ; T. Wustefeld ; L. Aeberhard ; T. R. Kress ; N. Muthalagu ; L. Rycak ; R. Rudalska ; R. Moll ; S. Kempa ; L. Zender ; M. Eilers ; D. J. Murphy
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: AMP-Activated Protein Kinases/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Apoptosis ; Carcinoma, Hepatocellular/drug therapy/genetics/metabolism/pathology ; Cell Line, Tumor ; Cell Respiration ; Cell Survival ; Cell Transformation, Neoplastic/genetics ; Disease Models, Animal ; Doxycycline/pharmacology ; Electron Transport ; *Gene Expression Regulation, Neoplastic ; Genes, myc/*genetics ; Glutamine/metabolism ; Homeostasis ; Humans ; Liver Neoplasms/drug therapy/genetics/metabolism/pathology ; Mice ; Mitochondria/metabolism ; Multiprotein Complexes ; Oncogene Protein p55(v-myc)/genetics/metabolism ; Protein Biosynthesis ; Protein Kinases/deficiency/genetics/*metabolism ; Proteins/antagonists & inhibitors/metabolism ; RNA Interference ; Repressor Proteins/antagonists & inhibitors/deficiency/genetics/*metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolismPublished by: -
3S. Walz ; F. Lorenzin ; J. Morton ; K. E. Wiese ; B. von Eyss ; S. Herold ; L. Rycak ; H. Dumay-Odelot ; S. Karim ; M. Bartkuhn ; F. Roels ; T. Wustefeld ; M. Fischer ; M. Teichmann ; L. Zender ; C. L. Wei ; O. Sansom ; E. Wolf ; M. Eilers
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-07-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Binding Sites ; Cell Line, Tumor ; Down-Regulation/*genetics ; E-Box Elements/genetics ; Gene Expression Regulation, Neoplastic/*genetics ; Genes, myc/*genetics ; Humans ; Kruppel-Like Transcription Factors/metabolism ; Mice ; Neoplasms/*genetics ; Nuclear Proteins/metabolism ; Promoter Regions, Genetic/genetics ; Protein Inhibitors of Activated STAT/metabolism ; Proto-Oncogene Proteins c-myc/genetics/metabolism ; RNA Polymerase II/metabolism ; *Transcriptome ; Up-Regulation/*geneticsPublished by: -
4Staff View
ISSN: 0304-419XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1420-9071Keywords: c-myc ; max ; oncogene ; transcription ; cell cycle ; apoptosisSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract c-myc was discovered as the cellular homologue of the transduced oncogene of several avian retroviruses. The gene encodes a transcription factor, which forms a heteromeric protein complex with a partner protein termed Max. In mammalian cells, Myc is a central regulator of cell proliferation and links external signals to the cell cycle machinery. Myc also induces cells to undergo apoptosis, unless specific signals provided either by cytokines or by oncogenes block the apoptotic pathway. Recent progress sheds light both on the factors regulating the function and expression of Myc and on the downstream targets in the cell cycle. Together, these findings suggest the existence of a novel signal transduction pathway regulating both apoptosis and proliferation.Type of Medium: Electronic ResourceURL: