Search Results - (Author, Cooperation:M. E. Smith)
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1Latest Papers from Table of Contents or Articles in PressSaunders, M. E., Smith, T. J., Rader, R.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressL. Tedersoo ; M. Bahram ; S. Polme ; U. Koljalg ; N. S. Yorou ; R. Wijesundera ; L. Villarreal Ruiz ; A. M. Vasco-Palacios ; P. Q. Thu ; A. Suija ; M. E. Smith ; C. Sharp ; E. Saluveer ; A. Saitta ; M. Rosas ; T. Riit ; D. Ratkowsky ; K. Pritsch ; K. Poldmaa ; M. Piepenbring ; C. Phosri ; M. Peterson ; K. Parts ; K. Partel ; E. Otsing ; E. Nouhra ; A. L. Njouonkou ; R. H. Nilsson ; L. N. Morgado ; J. Mayor ; T. W. May ; L. Majuakim ; D. J. Lodge ; S. S. Lee ; K. H. Larsson ; P. Kohout ; K. Hosaka ; I. Hiiesalu ; T. W. Henkel ; H. Harend ; L. D. Guo ; A. Greslebin ; G. Grelet ; J. Geml ; G. Gates ; W. Dunstan ; C. Dunk ; R. Drenkhan ; J. Dearnaley ; A. De Kesel ; T. Dang ; X. Chen ; F. Buegger ; F. Q. Brearley ; G. Bonito ; S. Anslan ; S. Abell ; K. Abarenkov
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-11-29Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: DNA Barcoding, Taxonomic ; Forests ; Fungi/*classification/genetics/*physiology ; Geography ; Grassland ; *Soil ; *Soil Microbiology ; TundraPublished by: -
3Latest Papers from Table of Contents or Articles in PressE. M. Smith, T. C. Marshall, S. Karunarathne, R. Siedlecki, M. Stolzenburg
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-02-17Publisher: Wiley-BlackwellPrint ISSN: 0148-0227Topics: GeosciencesPhysicsPublished by: -
4Latest Papers from Table of Contents or Articles in PressJ. P. Magnusson ; C. Goritz ; J. Tatarishvili ; D. O. Dias ; E. M. Smith ; O. Lindvall ; Z. Kokaia ; J. Frisen
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-10-11Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Astrocytes/cytology/*physiology ; Corpus Striatum/pathology/physiopathology ; Gene Deletion ; Immunoglobulin J Recombination Signal Sequence-Binding Protein/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neural Stem Cells/cytology/*physiology ; Neurogenesis/genetics/*physiology ; Neurons/cytology/*physiology ; Receptor, Notch1/genetics/*physiology ; *Signal Transduction ; Stroke/pathology/*physiopathologyPublished by: -
5Latest Papers from Table of Contents or Articles in PressGryganskyi, A. P., Golan, J., Dolatabadi, S., Mondo, S., Robb, S., Idnurm, A., Muszewska, A., Steczkiewicz, K., Masonjones, S., Liao, H.-L., Gajdeczka, M. T., Anike, F., Vuek, A., Anishchenko, I. M., Voigt, K., de Hoog, G. S., Smith, M. E., Heitman, J., Vilgalys, R., Stajich, J. E.
Genetics Society of America (GSA)
Published 2018Staff ViewPublication Date: 2018-06-01Publisher: Genetics Society of America (GSA)Electronic ISSN: 2160-1836Topics: BiologyPublished by: -
6Latest Papers from Table of Contents or Articles in PressGelbard, A., Shyr, Y., Berry, L., Hillel, A. T., Ekbom, D. C., Edell, E. S., Kasperbauer, J. L., Lott, D. G., Donovan, D. T., Garrett, C. G., Sandhu, G., Daniero, J. J., Netterville, J. L., Schindler, J. S., Smith, M. E., Bryson, P. C., Lorenz, R. R., Francis, D. O.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-04-12Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Ear, nose and throat/otolaryngologyPublished by: -
7Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The primary migration of lymphocytes from the blood was compared in nude rats and in euthymic rats. The flatter endothelium in the post-capillary venules (PCV) in the lymph nodes of nude rats was as efficient as the high endotheluim of PCV in euthymic rats at capturing both T and B lymphocytes from the blood, although lymphocytes took a longer time to cross the PCV wall in nude recipients. The organ distribution of both lymphocytes and lymphoblasts ([125I]UdR-labelled cells) was broadly similar in nude and euthymic recipients. A second aim was to compare B and T lymphocytes with respect to the rate and sites at which they leave the blood after intravenous injection. As judged by sampling venous blood, B lymphocytes left the blood faster, but this was partly attributable to a larger intravascular pool of B lymphocytes in small blood vessels, especially in the lung. Thoracic duct lymphocytes from nude rats collected under standard conditions (16 h, 0°C) entered the cervical lymph nodes very poorly, but when lymphocyte transfer was performed under more physiological conditions entry of B lymphocytes into lymph nodes was about half that of T lymphocytes. B lymphocytes did show a slight preference for entry into Peyer's patches compared with lymph nodes.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesFOSSUM, S. ; SMITH, M. E. ; BELL, E. B. ; FORD, W. L.
Oxford, UK : Blackwell Publishing Ltd
Published 1980Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The lymph nodes (LN) of the congenitally athymic nude rat (rnu) were compared with the LN of non-nude littermates. The mesenteric and coeliac LN were smaller in the rnu rats, but the axillary and the cervical LN were larger. Germinal centres were found in the LN of nude rats. They were scarce and often very small, but some were of normal structure, especially in the cervical LN. The endothelium of post-capillary venules in the LN paracortex was usually flat, but occasionally plump endothelium, typical of post-capillary venules in the LN of normal rats, was seen. The paracortex was extremely depleted of lymphocytes but remained a distinct area occupied predominantly by pale interdigitating cells. In some LN the medullary sinuses were distended and the cords engorged with plasma cells. The predominant cells in thoracic duct lymph were immunoglobulin-positive B lymphocytes. The hourly output of these cells was the same as that in non-nude littermates. However, small numbers of thoracic duct cells were positive for the markers identified by the monoclonal antibodies W3/13 and W3/25, although in normal rats these are not expressed on small B lymphocytes.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National Licensesvan Eck, E. R. H. ; Smith, M. E.
College Park, Md. : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The static 17O NMR spectra of Mg(OH)2 and amorphous Mg(OH)x(OCH3)2−x were measured. Simulation of these spectra gave e2qQ/h=6.8 MHz, η=0, and δiso=20 ppm, and e2qQ/h=7.25 MHz, η=0, and δiso=−25 ppm for the hydroxyl oxygen in, respectively, Mg(OH)2 and Mg(OH)x(OCH3)2−x. An OH distance in Mg(OH)2 of 1.001 Å was obtained using Lee–Goldberg decoupling to obtain the OH dipolar coupling constant. Dipolar oscillations in the 1H–17O cross-polarization curve provided an OH distance of 0.995 Å in Mg(OH)x(OCH3)2−x; these oscillations were not observed in Mg(OH)2. Based on differences in the OH distance and in the 17O quadrupole coupling constant it was concluded that the OH bond in Mg(OH)x(OCH3)2−x was more covalent. 17O 2D quadrupole separated local field experiments were performed on both samples in order to obtain the relative orientation of the 17O quadrupole and OH dipole tensors. In both cases the interaction tensors were found to be collinear. Lee–Goldberg decoupling during the dipolar evolution time t1 improved the resolution in the dipolar dimension. The resolution in the dipolar dimension of the 2D spectra obtained without proton decoupling during t1 was better for the Mg(OH)x(OCH3)2−x sample than for the Mg(OH)2 sample. Since the effect of the homonuclear proton dipolar coupling was less prominent in the amorphous sample, as evidenced by difference in CP-dynamics and spectral resolution, it was concluded that the hydroxyl groups were more isolated in the amorphous sample. The simulation of 2D separated quadrupole local field spectra showed that the experiment is very sensitive to differences in the relative quadrupole and dipole tensor orientation. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesSmith, M E F ; Awasthi, R ; O'Shaughnessy, S ; Fisher, C
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Aims : To investigate the differentiation pattern of epithelioid sarcoma in terms of perineurial and endothelial differentiation, and its relationship to that of meningioma.Methods and results : Nine cases of epithelioid sarcoma and five cases of meningioma were studied in an immunohistochemical analysis of ‘perineurial’ antigens [GLUT-1, claudin-1, epithelial membrane antigen (EMA) and VE-cadherin] and of ‘endothelial’ antigens not present on normal perineurium (CD34, CD31, Fli-1). Both epithelioid sarcoma and meningioma showed frequent expression of the perineurial markers GLUT-1, claudin-1 and EMA. VE-cadherin was identified in one of five meningiomas, and in the only case of epithelioid sarcoma in which suitably fixed material was available. CD34 was expressed by all epithelioid sarcomas studied but by none of the meningiomas. Fli-1 was present in a substantial majority of epithelioid sarcomas and by all the meningiomas. CD31 was not detected in any epithelioid sarcoma or meningioma.Conclusions : The results were evaluated in the context of previous immunohistochemical, ultrastructural and genetic studies and suggest that epithelioid sarcoma may be a form of malignant perineurioma with a range of differentiation (epithelial features) akin to that seen in meningioma, reflecting the close relationship between perineurium and meningothelium.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesGETHI, J G ; SMITH, M E ; MITCHELL, S E ; KRESOVICH, S
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1365-3180Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: The parasitic angiosperms, Striga hermonthica and Striga asiatica, severely constrain cereal production in sub-Saharan Africa by causing huge losses in grain yield. Understanding the diversity of Striga populations is important because it allows identification of races or biotypes thus improving chances of breeding success. Amplified fragment length polymorphism (AFLP) analysis was used to study genetic diversity among 17 populations of S. asiatica and 24 populations of S. hermonthica from Kenya. A total of 349 DNA fragments ranging from 51 to 500 bp were obtained from four EcoRI and MseI primer combinations. Genetic distances for S. asiatica populations ranged from 0.009 to 0.116 with a mean of 0.032. S. hermonthica populations had a genetic distance that ranged from 0.007 to 0.025 with a mean of 0.015. Only two clusters were found in S. asiatica populations whereas no apparent structure was evident in S. hermonthica populations. There was no evidence of isolation by distance for the two species. Although the low genetic diversity suggests Striga is relatively uniform across the populations studied, it is possible that pathogenicity and virulence genes may be located in genomic regions that were not sampled. The data, however, does not provide evidence to support diversification of both Striga species in the region where the study was conducted.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesBelk, M. C. ; Johnson, J. B. ; Wilson, K. W. ; Smith, M. E. ; Houston, D. D.
Oxford, UK : Munksgaard International Publishers
Published 2005Staff ViewISSN: 1600-0633Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyAgriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract – Leatherside chub (Snyderichthyes copei Jordan & Gilbert) comprises two lineages (northern and southern) whose centres of geographical range differ by about 3° latitude corresponding to about 30% shorter growing season and about 2 °C lower mean temperature during the growing season. We document patterns of variation in size-at-age among populations of leatherside chub in nature, and we test for variation in intrinsic growth rate of juvenile chub in a common-environment experiment to determine if lineages exhibit different intrinsic growth rates. Northern leatherside chubs at ages 1–3 were about 15% shorter in length compared with southern populations. Variation in hatching date or age at maturity could not account for differences in growth and body size, suggesting that temperature-specific intrinsic growth rates differed among populations. Based on a common environment experiment, we found that reaction norms for temperature-specific growth in length and mass were crossed. At the lower temperature, individuals from the north exhibited higher intrinsic growth in length, and at the higher temperature individuals from the south exhibited higher intrinsic growth in mass. Crossing reaction norms for temperature-specific intrinsic growth rates support a model of local adaptation to thermal regime.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesSmith, M. E. ; Crighton, A. J. ; Chisholm, D. M. ; Mountain, R. E.
Oxford, UK : Blackwell Publishing Ltd
Published 1999Staff ViewISSN: 1600-0714Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The simultaneous involvement of the mucous membranes of the oral cavity and upper aerodigestive tract by lesions characterised clinically by an intensely erythematous, lobulated surface and histologically by a dense connective tissue in- Key words: plasma cell mucositis filtrate composed of non-neoplastic plasma cells may be called plasma cell mucositis. We present a review of the literature, consisting of 14 cases, outlining the Malvin Smith, Unit of Oral Medicine and multifocal site distribution, chronicity and systemic background that distin- Surgery, Dental School, Park Place, Dundee, DD1 4HR, Scotland guish this entity and report a single case with confirmation of the polyclonal nature of the plasma cell infiltrate using gene rearrangement studies.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Routine swimming speed of larval red drum Sciaenops ocellatus increased throughout development but most rapidly for larvae 〉10 mm LT. Red drum of all sizes swam faster than predicted by published summary equations based on other species, possibly due to more advanced development at a given length. Frequency and magnitude of startle responses increased over the larval period for both types of stimuli with most of the improvement taking place before larvae reached 8 mm LT. Time to response for an acoustic and visual stimulus decreased early in the larval period but levelled off after 10 mm LT. Response distance and response speed for both stimuli generally increased throughout the larval period, but response duration remained constant. Visually stimulated responses were generally longer in duration and distance covered than acoustically stimulated responses, while mean response speeds were similar.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The recirculation of lymphocytes through the tissues and their return to the blood were compared in nude and euthymic rats. Three approaches were used: the organ distribution of 15Cr-labelled lymphocytes from nude or euthymic donors at 24 h after injection: the compartmental distribution of B and T lymphocytes as assessed by autoradiography of the spleen, lymph nodes, and Peyer's patches; and the tempo of recirculation from blood to thoracic duct lymph as estimated by counting timed fractions of lymph from a recipient of labelled lymphocytes. The following conclusions were drawn: (1) The distribution of lymphocytes between organs and wilhin organs is very similar in nude and euthymic recipients. In particular, B lymphocytes proceed normally to the follicular areas in the absence of T cells. (2) The recircufation from blood to lymph is delayed in nude rats. (3) For equal numbers of B and T cells injected intravenously about half as many B cells as T cells enter mesenteric and cervical lymph nodes, but approximately equal numbers of B and T cells enter the spleen and Peyer's patches.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesFORD, W. L. ; ROLSTAD, B. ; FOSSUM, S. ; HUNT, S. V. ; SMITH, M. E. ; SPARSHOTT, S. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1981Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Two experiments are described concerned with the mechanism of host cell activation in the rat popliteal lymph node (LN) undergoing a graft-versus-host (GVH) reaction. (1) Irradiated, F1 hybrid hosts (750 rad) mounted an impaired response to parental strain T cells. This was augmented by an intravenous injection of F1 hybrid lymphocytes but not by parental strain B lymphocytes syngeneic with the initiating T cells. When the donor T cells (footpad) und B lymphocytes (intravenous) were completely allogeneic the residual response of the irradiated F1 was completely inhibited. (2) The popliteal LN response in the semi-allogeneic situation of the type (A × C)F1→(B × C)F1 was, if anything, weaker than in the allogeneic situation AA→BB. These results and other data are discussed in terms of a possible major histocompatibility complex (MHC) requirement for host cell activation. The sharing of an MHC haplotype between donor and host cells is unlikely to be a necessary or sufficient condition for host cell activation.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesSmith, M E F ; Brown, J I ; Fisher, C
Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
Published 1998Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: To evaluate the pattern of cadherin expression in epithelioid sarcoma.〈section xml:id="abs1-2"〉〈title type="main"〉Methods and resultsSeven epithelioid sarcomas were immunostained by a polyclonal antibody that detects all cadherin subtypes and by monoclonal antibodies that detect epithelial cadherin (E-cadherin) and vascular-endothelial cadherin (VE cadherin). In addition, the tumours were immunostained for a variety of epithelial (cytokeratin, EMA, AUA1) and endothelial (Factor VIII-related antigen, CD34, CD31) markers. Tumour cells of all seven epithelioid sarcomas expressed cadherins. Surprisingly, E-cadherin was not detected in any of the sarcomas. VE-cadherin was detected in five of seven cases. All seven tumours expressed cytokeratins and EMA but none expressed AUA1. CD34 was detected in six of seven cases and CD31 was detected in a single case. No case expressed Factor VIII-related antigen.〈section xml:id="abs1-3"〉〈title type="main"〉ConclusionsMost epithelioid sarcomas strongly express cadherins, a feature which may contribute to their epithelioid appearance. The absence of detectable E-cadherin suggests that epithelial differentiation in these tumours is, at most, incomplete. The expression of VE-cadherin by the majority of cases, in the absence of E-cadherin, is consistent with an element of mesenchymal differentiation, possibly endothelial or perineurial. The additional presence of other markers such as CD34 and CD31 in some cases favours endothelial differentiation.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesMcCluggage, W G ; Catherwood, M ; Alexander, H D ; McBride, H A ; Smith, M E F ; Morris, T C M
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Aims: Although diffuse large B-cell lymphoma is categorized as a distinct entity in the REAL classification of lymphomas, it represents a heterogeneous group of neoplasms. A subgroup is probably of follicle centre cell origin and may evolve from a pre-existing follicular lymphoma. The t(14;18) chromosomal translocation can be demonstrated in the majority of follicular lymphomas and the aim of this study was to investigate the prevalence of t(14;18) translocation in a series of de novo nodal diffuse large B-cell lymphomas. We correlated this with the immunohistochemical expression of CD10, bcl2 and bcl6, markers which are usually expressed by the neoplastic cells in follicular lymphomas. We also correlated these parameters with the presence or absence of p53 protein expression by the neoplastic cells.Methods and results: Nodal diffuse large B-cell lymphomas (n=34) were stained immunohistochemically with monoclonal antibodies to CD10, bcl2, bcl6 and p53 (D07). Polymerase chain reaction (PCR) for the t(14;18) translocation was also performed. Fourteen, 24 and 29 (41%, 71%, 85%) cases exhibited positivity for CD10, bcl2 and bcl6, respectively. In 12 cases there was positivity with D07 (35%). By PCR, the t(14;18) translocation was identified in five cases (15%), four of which were positive for CD10 and bcl2 and all of which were positive for bcl6. One of five cases positive for the chromosomal translocation exhibited positivity with D07.Conclusions: In this study the t(14;18) translocation was identified in 15% of diffuse large B-cell lymphomas, all but one of which exhibited positivity for CD10, bcl2 and bcl6. These may represent cases of follicle centre cell origin which may or may not have evolved from a pre-existing follicular lymphoma. It is possible that positivity for CD10 especially may identify cases which are of follicle centre cell origin and that the absence of t(14;18) translocation in some of these cases may reflect the fact that the translocation cannot normally be demonstrated in all follicular lymphomas. Whether the presence or absence of the translocation and the immunophenotype are prognostically important should be investigated further.Type of Medium: Electronic ResourceURL: