Search Results - (Author, Cooperation:M. E. Harris)

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  1. 1
    U. P. Guenther ; L. E. Yandek ; C. N. Niland ; F. E. Campbell ; D. Anderson ; V. E. Anderson ; M. E. Harris ; E. Jankowsky
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-09-24
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    5' Untranslated Regions/genetics ; Base Sequence ; Escherichia coli/*enzymology/genetics ; Escherichia coli Proteins/chemistry/genetics/*metabolism ; Kinetics ; Nucleic Acid Conformation ; RNA Precursors/chemistry/genetics/metabolism ; RNA, Bacterial/chemistry/genetics/metabolism ; RNA, Transfer/chemistry/genetics/*metabolism ; RNA, Transfer, Met/chemistry/genetics/metabolism ; Ribonuclease P/chemistry/genetics/*metabolism ; Substrate Specificity
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Aksenov, M. Yu. ; Aksenova, M. V. ; Harris, M. E. ; Hensley, K. ; Butterfield, D. A. ; Carney, J. M.

    Oxford, UK : Blackwell Science Ltd
    Published 1995
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: The β-amyloid peptide (Aβ), a main constituent in both senile and diffuse plaques in Alzheimer's disease brains, was previously shown to be neurotoxic and to be able to interact with several macromolecular components of brain tissue. Previous investigations carried out in our laboratory demonstrated free radical species formation in aqueous solutions of Aβ(1–40) and its C-end fragment, Aβ(25–35). Toxic forms of Aβ rapidly inactivate the oxidation-sensitive cytosolic enzyme glutamine synthetase (GS). In this regard, we suggested and subsequently demonstrated that Aβ radicals can cause an oxidative damage of cell proteins and lipids resulting in disruption of membrane functions, enzyme inactivation, and cell death. Because GS can be a substrate for Aβ-derived oxidizing species, the present study was conducted to determine if GS could protect against Aβ neurotoxicity. In contrast to this initial hypothesis, we here report that GS significantly enhances the neurotoxic effects of Aβ(1–40). The Aβ-mediated inactivation of GS was found to be accompanied by the loss of immunoreactive GS and the significant increase of Aβ(1–40) neurotoxicity.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1471-4159.1995.65041899.x

    Articles: DFG German National Licenses
  3. 3
    JOHNSTON, R. W. ; HARRIS, M. E. ; MORAN, A. B.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1978
    Staff View
    ISSN:
    1745-4565
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Raw beef rounds were surface inoculated with salmonellae. Some of the rounds were mechanically blade tenderized. Both surface and core samples from each round studied were examined for the presence of and the logarithmic level of salmonellae. Mechanical tenderization increased the level of salmonellae found in core samples by about one logarithm. Large samples taken from cores of rounds which were not tenderized contained small numbers of salmonellae. Dipping inoculated rounds into a 50 ppm chlorine solution did not prevent the occurrence of salmonellae in core samples of mechanically tenderized units. Salmonella survived in the core and on the surface of some but not all inoculated rounds cooked to an internal temperature of 130°F.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1745-4565.1978.tb00273.x

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1749-6632.1996.tb39057.x

    Articles: DFG German National Licenses
  5. 5
    Harris, M. E.
    Springer
    Published 1980
    Staff View
    ISSN:
    1588-2829
    Keywords:
    Primary 20D45 ; Abelianp-group ; p′-automorphism
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mathematics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02107573

    Articles: DFG German National Licenses