Search Results - (Author, Cooperation:M. Dunn)

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  1. 1
    Staff View
    Publication Date:
    2018-03-22
    Publisher:
    Royal Society
    Electronic ISSN:
    2054-5703
    Topics:
    Natural Sciences in General
    Keywords:
    computational biology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
  3. 3
  4. 4
    Staff View
    Publication Date:
    2018-02-10
    Publisher:
    Royal Society
    Electronic ISSN:
    2054-5703
    Topics:
    Natural Sciences in General
    Keywords:
    evolution, health and disease and epidemiology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    K. Howe ; M. D. Clark ; C. F. Torroja ; J. Torrance ; C. Berthelot ; M. Muffato ; J. E. Collins ; S. Humphray ; K. McLaren ; L. Matthews ; S. McLaren ; I. Sealy ; M. Caccamo ; C. Churcher ; C. Scott ; J. C. Barrett ; R. Koch ; G. J. Rauch ; S. White ; W. Chow ; B. Kilian ; L. T. Quintais ; J. A. Guerra-Assuncao ; Y. Zhou ; Y. Gu ; J. Yen ; J. H. Vogel ; T. Eyre ; S. Redmond ; R. Banerjee ; J. Chi ; B. Fu ; E. Langley ; S. F. Maguire ; G. K. Laird ; D. Lloyd ; E. Kenyon ; S. Donaldson ; H. Sehra ; J. Almeida-King ; J. Loveland ; S. Trevanion ; M. Jones ; M. Quail ; D. Willey ; A. Hunt ; J. Burton ; S. Sims ; K. McLay ; B. Plumb ; J. Davis ; C. Clee ; K. Oliver ; R. Clark ; C. Riddle ; D. Elliot ; G. Threadgold ; G. Harden ; D. Ware ; S. Begum ; B. Mortimore ; G. Kerry ; P. Heath ; B. Phillimore ; A. Tracey ; N. Corby ; M. Dunn ; C. Johnson ; J. Wood ; S. Clark ; S. Pelan ; G. Griffiths ; M. Smith ; R. Glithero ; P. Howden ; N. Barker ; C. Lloyd ; C. Stevens ; J. Harley ; K. Holt ; G. Panagiotidis ; J. Lovell ; H. Beasley ; C. Henderson ; D. Gordon ; K. Auger ; D. Wright ; J. Collins ; C. Raisen ; L. Dyer ; K. Leung ; L. Robertson ; K. Ambridge ; D. Leongamornlert ; S. McGuire ; R. Gilderthorp ; C. Griffiths ; D. Manthravadi ; S. Nichol ; G. Barker ; S. Whitehead ; M. Kay ; J. Brown ; C. Murnane ; E. Gray ; M. Humphries ; N. Sycamore ; D. Barker ; D. Saunders ; J. Wallis ; A. Babbage ; S. Hammond ; M. Mashreghi-Mohammadi ; L. Barr ; S. Martin ; P. Wray ; A. Ellington ; N. Matthews ; M. Ellwood ; R. Woodmansey ; G. Clark ; J. Cooper ; A. Tromans ; D. Grafham ; C. Skuce ; R. Pandian ; R. Andrews ; E. Harrison ; A. Kimberley ; J. Garnett ; N. Fosker ; R. Hall ; P. Garner ; D. Kelly ; C. Bird ; S. Palmer ; I. Gehring ; A. Berger ; C. M. Dooley ; Z. Ersan-Urun ; C. Eser ; H. Geiger ; M. Geisler ; L. Karotki ; A. Kirn ; J. Konantz ; M. Konantz ; M. Oberlander ; S. Rudolph-Geiger ; M. Teucke ; C. Lanz ; G. Raddatz ; K. Osoegawa ; B. Zhu ; A. Rapp ; S. Widaa ; C. Langford ; F. Yang ; S. C. Schuster ; N. P. Carter ; J. Harrow ; Z. Ning ; J. Herrero ; S. M. Searle ; A. Enright ; R. Geisler ; R. H. Plasterk ; C. Lee ; M. Westerfield ; P. J. de Jong ; L. I. Zon ; J. H. Postlethwait ; C. Nusslein-Volhard ; T. J. Hubbard ; H. Roest Crollius ; J. Rogers ; D. L. Stemple
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-04-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Chromosomes/genetics ; Conserved Sequence/*genetics ; Evolution, Molecular ; Female ; Genes/genetics ; Genome/*genetics ; Genome, Human/genetics ; Genomics ; Humans ; Male ; Meiosis/genetics ; Molecular Sequence Annotation ; Pseudogenes/genetics ; Reference Standards ; Sex Determination Processes/genetics ; Zebrafish/*genetics ; Zebrafish Proteins/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    R. Bouckaert ; P. Lemey ; M. Dunn ; S. J. Greenhill ; A. V. Alekseyenko ; A. J. Drummond ; R. D. Gray ; M. A. Suchard ; Q. D. Atkinson
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-08-28
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Agriculture/history ; Bayes Theorem ; *Cultural Evolution ; History, Ancient ; Humans ; Language/*history ; Linguistics/history ; Phylogeography ; Turkey ; Vocabulary
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Staff View
    Publication Date:
    2018-11-14
    Publisher:
    American Chemical Society (ACS)
    Print ISSN:
    0006-2960
    Electronic ISSN:
    1520-4995
    Topics:
    Biology
    Chemistry and Pharmacology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
    M. Dunn ; S. J. Greenhill ; S. C. Levinson ; R. D. Gray
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-04-15
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Biological Evolution ; Cultural Evolution ; Humans ; *Language ; *Linguistics ; Phylogeny
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  9. 9
    FARHADIAN, ZIBA ; M. DUNN, ROBERT

    Oxford, UK : Blackwell Publishing Ltd
    Published 1986
    Staff View
    ISSN:
    1467-6435
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Sociology
    Economics
    Notes:
    The monetarist model of the balance of payments concludes that payments deficits are caused by inappropriate central bank decisions under the unstated assumption that such institutions are independent and hence that the growth of the domestic assets of the central bank can be viewed as an exogenous or decision variable. It is argued in this paper that this assumption is incorrect for developing countries with relatively primitive or ‘thin’ capital markets. In such countries there is no alternative to financing central government budget deficits through the central bank. As a result such deficits are the true decision variable and ultimately determine the behavior of the balance of payments through their impact on the expansion of the central bank's domestic assets. In countries with more developed financial markets, however, alternative means of financing government budget deficits do exist, and the central bank can more reasonably be viewed as independent.This hypothesis is tested by substituting the government budget deficit for the growth of the central bank's domestic assets in a typical monetarist model of the balance of payments. It is predicted that this substitution will work well for those countries with very limited or underdeveloped capital markets. An index of financial development is then derived and 54 countries are divided into three groups on the basis of the extent of such capital market ‘deepening’. The empirical results support the previously stated hypothesis in that the substitution of the government deficit for the growth of the central bank's domestic assets in a monetarist payments model is successful for those countries with the least developed financial systems, moderately successful for the intermediate group, and decidedly unsuccessful for countries with highly developed capital markets. It is suggested that for most underdeveloped countries the monetarist model of the balance of payments might be better viewed as a fiscal policy model, but that the traditional monetarist model remains relevant for the industrialized countries.〈section xml:id="abs1-2"〉〈title type="main"〉ZUSAMMENFASSUNGDas monetaristische Zahlungsbilanzmodell zeigt, dass Zahlungsbilanzdefizite durch unangebrachte Zentralbankentscheidungen verursacht werden, und zwar unter der impliziten Annahme, dass derartige Institutionen unabhängig seien und daher das Wachstum der inländischen Aktiva als exogen oder Entscheidungsvariable ange-sehen werden kann. Bezugnehmend auf Entwicklungsländer mit verhältnismässig primitiven oder schwachen Kapitalmärkten wird die vorerwähnte Annahme in diesem Papier als unrichtig angesehen. Es gibt in diesen Ländern keine Alternative für die Finanzierung der Haushaltsdefizite der Zentralregierung durch die Zentralbank. Diese Haushaltsdefizite stellen daher die wahre Entscheidungsvariable dar und bestimmen schliesslich das Zahlungsbilanzverhalten durch ihre Auswirkung auf das Wachstum der Inlandsaktiva der Zentralbank. In Lándern mit stárkeren Finanz-márkten gibt es jedoch alternative Möglichkeiten zur Finanzierung von Haushalts-defiziten, und in solch einem Fall kann die Zentralbank schon eher als unabhängig betrachtet werden.Diese Hypothese wird in einem typischen monetaristischen Zahlungsbilanzmodell auf die Probe gestellt, indem das Haushaltsdefizit durch das Wachstum der Inlandsaktiva der Zentralbank ersetzt wird. Es wird angenommen, dass dieser Aus-tausch bei Ländern mit sehr eingeschrankten oder schwach entwickelten Kapitalmarkten erfolgversprechend sein wird. Über die finanzpolitische Entwicklung wird dann ein Index aufgestellt und auf der Grundlage des Ausmasses einer solchen Kapitalmarktkräftigung (deepening) werden 54 Länder in drei Gruppen aufgeteilt. Die vorgenannte Hypothese, nämlich dass der Austausch des Haushaltsdefizits gegen steigende Inlandsaktiva der Zentralbank in einem monetaristischen Zahlungsbilanz-modell für Länder mit schwach entwickelten Finanzsystemen ziemlich erfolgreich ist, sich jedoch weniger erfolgversprechend anlässt für die Ländergruppe mit stärkeren Finanzsystemen, und entschieden erfolglos für Länder mit ausgesprochen starken Kapitalmärkten ist, wird durch die empirischen Ergebnisse untermauert. Es wird darauf hingewiesen, dass das monetaristische Zahlungsbilanzmodell für die Mehrzahl der Entwicklungsländer vorzugsweise als fiskalpolitisches Modell angesehen werden sollte, während für die Industrieländer auch weiterhin das traditionelle monetaristische Modell relevant bleibt.〈section xml:id="abs1-3"〉〈title type="main"〉RÉSUMÉLa théorie monétariste de la balance des paiements suggère que les déficits extérieurs sont causés par des politiques monétaires inadéquates de la banque centrale, en supposant que ces politiques peuvent être considérées comme indépendantes et done exogénes. Cet article maintient qu'une telle supposition ne s'applique pas aux pays en voie de développement avec des marchés financiers peu développés. Dans de tels pays, il n'y a pas d'autre alternative mais de financer les déficits budgétaires par le recours à la banque centrale. Ces déficits sont done les vrais variables de décision et déterminent le comportement de la balance des paiements par leur influence sur l'expansion du crédit par la banque centrale. Dans des pays à marché financiers plus développés, il existe d'autres moyens de financer les déficits budgétaires, et la banque centrale peut done être considérée comme indépendante.L'hypothese considérée ci-dessus est testée en substituant la variable représentant le niveau du déficit budgétaire celle représentant l'expansion du crédit par la banque centrale dans un modéle monétariste de la balance des paiements. L'hypothese est que cette substitution produira des résultats empiriques meilleurs dans le cas des pays à marchés financiers peu développés. L'on dérive par la suite un indice du développement financier sur la base d'une mesure de la “profondeur” des marchés financiers. Les résultats empiriques supportent l'hypothèse avancée dans la mesure où le déficit de la balance des paiements est statistiquement bien expliquée par le variable déficit budgétaire dans le cas des pays à marchés financiers trés peu développés, et mal expliquée dans le cas des pays à marchés financiers trés développés. L'article conclut que pour la plupart des pays en voie de développement, le modèle monétariste s'interprete mieux comme modèle fiscaliste, mais que le modèle monétariste tradi-tionnel reste valable pour les pays industrialisés.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1475-2743
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Geosciences
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    Abstract. An effective fertilizer recommendation system requires information on seasonal, soil-related and cultural variations in soil mineral nitrogen (N) and nutrient requirements of the crop. This can be provided by dynamic N turnover models, such as listed by Plentinger & Penning De Vries (1996). In this paper, we describe a survey of farmer opinion designed to ascertain what farmers want from such a decision support system. Over 100 farmers were surveyed. Surveyed farmers requested that default values be available for all model inputs. Inputs should be entered both by windows-based menu (for clarity) and tabular format (for speed), have user-selected units, and be fully supported by context-sensitive help. The system should have a hierarchical structure allowing access to fixed parameters, and be compatible with commonly used farm recording packages. Recommendations should be provided both for the field (single and optional application rates), and in tabular format across the whole farm. Simulations should be easily rerun using more recent crop and weather data. Turnover processes underlying recommendations should be illustrated by flow diagrams of flux between pools, pie charts of fertilizer fate, bar charts of movement down the soil profile and graphical plots of changes in N status against time.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Edwards, T. J. ; Turnbull, G. A. ; Dunn, M. H. ; Ebrahimzadeh, M.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1998
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    A high-power continuous-wave optical parametric oscillator based on the nonlinear material KTiOAsO4 and pumped internal to a tunable Ti:sapphire laser is described. The use of the intracavity pumping approach has enabled operation of a singly resonant oscillator (SRO), resulting in the generation of as much as 1.46 W of infrared power in a 11.5-mm-long crystal. Amplitude-stable signal and idler outputs, each in excess of 500 mW, over the respective wavelength ranges of 1.11–1.20 and 2.44–2.86 μm have been extracted from the SRO. We demonstrate up to 90% down-conversion of the optimum Ti:sapphire output power to the SRO, confirming our recent theoretical predictions. The performance characteristics of the device demonstrate that practical, stable, and efficient operation of continuous-wave SROs at watt-level output power can be readily achieved in conventional birefringent materials by exploiting the intracavity pumping approach. © 1998 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Walkup, J. R. ; Dunn, M. ; Watson, D. K.

    College Park, Md. : American Institute of Physics (AIP)
    Published 2000
    Staff View
    ISSN:
    1089-7658
    Source:
    AIP Digital Archive
    Topics:
    Mathematics
    Physics
    Notes:
    A method of optimizing a sequence of economized rational approximants (ERAs) to produce a sequence of approximants with enhanced convergence properties is described. It is shown that such a technique improves upon the error of the Padé approximants at a chosen value of the independent variable, and in some cases leads to dramatic improvement, even in cases where Padé approximants behave erratically. The procedure is tested on six known functions, with improved convergence and accuracy in each case. The procedure is then applied to the problem of evaluating a perturbation series of an atomic system, diamagnetic hydrogen, with significant improvement in both convergence and accuracy as well. © 2000 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    MacVicar, John ; Dunn, M. F.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1969
    Staff View
    ISSN:
    1471-0528
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Colville, F. G. ; Ebrahimzadeh, M. ; Sibbett, W. ; Dunn, M. H.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    We have demonstrated a continuous-wave optical parametric oscillator that uses lithium triborate as the nonlinear material and a tunable Ti:sapphire laser as the pump source. By exploiting type I noncritical phase matching and a combination of temperature and pump frequency tuning, we have generated widely tunable radiation from 1.49 to 1.70 μm, limited by the bandwidth of the optical coatings. Total output powers of 30 mW and pump depletions of 40% have been obtained at two times the oscillation threshold of 360 mW. We discuss the application of this nonlinear frequency conversion process to several recently proposed experiments.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Colville, F. G. ; Padgett, M. J. ; Dunn, M. H.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    We have demonstrated a continuous-wave optical parametric oscillator that uses separate optical cavities to resonate independently the nondegenerate signal and idler frequencies. The three-mirror cavity utilizes the type II phase-matching geometry in lithium triborate, with the orthogonally polarized signal and idler fields separated by an intracavity, dichroic-coated, Brewster-angled beam splitter. This dual-cavity oscillator can overcome mode and cluster hopping effects, which are characteristic of doubly resonant, continuous-wave optical parametric oscillators. We measure a pump power threshold of ≈200 mW and smooth tuning over ≈0.4 GHz. The tuning range is limited by pump resonance effects within the idler cavity.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Lindsay, I. D. ; Petridis, C. ; Dunn, M. H. ; Ebrahimzadeh, M.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 2001
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    A continuous-wave pump-enhanced singly resonant optical parametric oscillator (OPO) directly pumped by a grating-stabilized external-cavity diode laser operating at (approximate)810 nm is described. The OPO was based on periodically poled LiNbO3 and could be tuned over 1.06–1.19 μm at the signal and 2.58–3.44 μm at the idler. The OPO threshold was typically 25–30 mW over the observed tuning range. Up to 4 mW of one-directional idler output was obtained for 62 mW of external-cavity diode laser pump power. The high stability of the external-cavity diode-laser pump source allowed locked, single-mode OPO operation for periods of greater than 1 h. © 2001 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    HUGHES, M. A. ; DUNN, M. A. ; PEARCE, R. S. ; WHITE, A. J. ; ZHANG, L.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1992
    Staff View
    ISSN:
    1365-3040
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    bltA is a barley gene which, as measured by steady state mRNA levels, is induced by a low positive temperature treatment of shoot meristems. The gene is also induced in shoot meristems by drought stress. We now report the response of this gene to foliar applications of abscisic acid. The striking similarity between the predicted amino acid sequence of bltA and two maize phospholipid transfer proteins indicates a biochemical function for the bltA gene product. This homology also demonstrates the hitherto unreported environmental regulation of expression of a phospholipid transfer protein which may involve abscisic acid in the signal transduction pathway.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    PEARCE, R. S. ; DUNN, M. A. ; RIXON, J. E. ; HARRISON, P. ; HUGHES, M. A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1365-3040
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    The purpose of this work was to examine environmental control of expression, at the mRNA level, of cold-inducible genes and to test the relationship of the expression of the genes to cold acclimation. Barley plants (Hordeum vulgare L. cv. Igri) at the three- to four-leaf stage were (a) grown in different temperature environments between 20/15°C and +4/-4°C or (b) transferred between 20/15°C and 6/2°C or (c) grown under drought or nutrient stress conditions. Frost hardiness (using a regrowth method) and mRNA levels for three cold-induced genes, blt4-9, blt14 and blt101, from meristematic crown tissue (vegetative shoot meristem plus subtending stem and associated root initials) were measured. Hardiness and levels of blt4-9, blt14 and blt101 mRNAs increased with lower growth temperatures, below a maximum inductive temperature. Prior temperature environment and plant age affected the rate of change in mRNA levels of these genes in response to a change of temperature environment. Hardiness was strongly correlated with mRNA levels of these genes in plants grown in different temperature environments. This correlation did not extend to plants exposed to drought or nutrient stresses. Implications are drawn for plant responses to a warmer climate.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Dunn, M. R. ; Pawson, M. G.

    Oxford, UK : Blackwell Publishing Ltd
    Published 2002
    Staff View
    ISSN:
    1095-8649
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    Plaice Pleuronectes platessa populations on the west coast of England and Wales are currently managed as two stocks: in ICES Division VIIa (Irish Sea, Cardigan Bay and St George's Channel), and ICES Divisions VIIf&g (Bristol Channel and Celtic Sea). A total of 13,784 plaice were fitted with Petersen tags and released in these areas during 1979–1980 and 1993–1996. Analysis of the 2788 recaptures received by June 2000 confirmed known spawning and feeding grounds in the region. It showed also that plaice 〉25 cm LT tended to undertake extensive spatial movements. At this size, female plaice were likely to be mature or maturing for the first time, whilst males were probably mature. Tag recaptures indicated resident sub-stocks of plaice in the north-east Irish Sea, the south-east Irish Sea, Cardigan Bay and Bristol Channel, a contingent of plaice in all areas that undertook permanent dispersal to other areas, and a contingent which originated in the south-east Irish Sea and migrated to spawn in the Bristol Channel. Plaice originating in the Bristol Channel rarely moved north into ICES Vila. A general hypothesis of plaice population structure in the region is presented and discussed in relation to stock assessment.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Dunn, M. ; Van Horn, E. ; Herman, S.H.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0005-7894
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses