Search Results - (Author, Cooperation:M. D. Cameron)
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1L. A. Solt ; Y. Wang ; S. Banerjee ; T. Hughes ; D. J. Kojetin ; T. Lundasen ; Y. Shin ; J. Liu ; M. D. Cameron ; R. Noel ; S. H. Yoo ; J. S. Takahashi ; A. A. Butler ; T. M. Kamenecka ; T. P. Burris
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adipose Tissue/drug effects/metabolism ; Animals ; Biological Clocks/drug effects/genetics/physiology ; Circadian Rhythm/*drug effects/genetics/*physiology ; Disease Models, Animal ; Energy Metabolism/*drug effects ; HEK293 Cells ; Humans ; Hypothalamus/drug effects/metabolism ; Liver/drug effects/metabolism ; Metabolome/drug effects ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Muscle, Skeletal/drug effects/metabolism ; Nuclear Receptor Subfamily 1, Group D, Member 1/*antagonists & ; inhibitors/metabolism ; Obesity/chemically induced/drug therapy/metabolism ; Pyrrolidines/*pharmacology ; Receptors, Cytoplasmic and Nuclear/*antagonists & inhibitors/metabolism ; Repressor Proteins/*antagonists & inhibitors/metabolism ; Thiophenes/*pharmacologyPublished by: -
2Z. Chen ; K. Cheng ; Z. Walton ; Y. Wang ; H. Ebi ; T. Shimamura ; Y. Liu ; T. Tupper ; J. Ouyang ; J. Li ; P. Gao ; M. S. Woo ; C. Xu ; M. Yanagita ; A. Altabef ; S. Wang ; C. Lee ; Y. Nakada ; C. G. Pena ; Y. Sun ; Y. Franchetti ; C. Yao ; A. Saur ; M. D. Cameron ; M. Nishino ; D. N. Hayes ; M. D. Wilkerson ; P. J. Roberts ; C. B. Lee ; N. Bardeesy ; M. Butaney ; L. R. Chirieac ; D. B. Costa ; D. Jackman ; N. E. Sharpless ; D. H. Castrillon ; G. D. Demetri ; P. A. Janne ; P. P. Pandolfi ; L. C. Cantley ; A. L. Kung ; J. A. Engelman ; K. K. Wong
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antineoplastic Combined Chemotherapy Protocols ; Benzimidazoles/*pharmacology/therapeutic use ; Biomarkers, Tumor/genetics/metabolism ; *Clinical Trials, Phase II as Topic ; *Disease Models, Animal ; Drug Evaluation, Preclinical ; Fluorodeoxyglucose F18 ; Genes, p53/genetics ; Humans ; Lung Neoplasms/*drug therapy/enzymology/*genetics/metabolism ; MAP Kinase Signaling System/drug effects ; Mice ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors ; Mutation/genetics ; Pharmacogenetics/*methods ; Positron-Emission Tomography ; Protein-Serine-Threonine Kinases/deficiency/genetics ; Proto-Oncogene Proteins/genetics/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics/metabolism ; Randomized Controlled Trials as Topic ; Reproducibility of Results ; Taxoids/*therapeutic use ; Tomography, X-Ray Computed ; Treatment Outcome ; ras Proteins/genetics/metabolismPublished by: -
3J. H. Choi ; A. S. Banks ; T. M. Kamenecka ; S. A. Busby ; M. J. Chalmers ; N. Kumar ; D. S. Kuruvilla ; Y. Shin ; Y. He ; J. B. Bruning ; D. P. Marciano ; M. D. Cameron ; D. Laznik ; M. J. Jurczak ; S. C. Schurer ; D. Vidovic ; G. I. Shulman ; B. M. Spiegelman ; P. R. Griffin
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-09-06Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 3T3-L1 Cells ; Adipocytes/drug effects/metabolism ; Adipose Tissue, White/drug effects/metabolism ; Animals ; Biphenyl Compounds/chemistry/pharmacology ; Body Fluids/drug effects ; COS Cells ; Cercopithecus aethiops ; Cyclin-Dependent Kinase 5/*antagonists & inhibitors ; Dietary Fats/pharmacology ; Disease Models, Animal ; Dose-Response Relationship, Drug ; HEK293 Cells ; Humans ; Hypoglycemic Agents/adverse effects/chemistry/*pharmacology ; Ligands ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Models, Molecular ; Obesity/chemically induced/metabolism ; Osteogenesis/drug effects ; PPAR gamma/agonists/chemistry/*metabolism ; Phosphorylation/drug effects ; Phosphoserine/metabolism ; Thiazolidinediones/adverse effects/pharmacology ; Transcription, Genetic/drug effects ; Tumor Necrosis Factor-alpha/pharmacology ; Weight Gain/drug effectsPublished by: -
4Mc; Cully, M. L., Ladell, K., Andrews, R., Jones, R. E., Miners, K. L., Roger, L., Baird, D. M., Cameron, M. J., Jessop, Z. M., Whitaker, I. S., Davies, E. L., Price, D. A., Moser, B.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-02-21Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
5Staff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1432-0614Source: Springer Online Journal Archives 1860-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Abstract The archetypal white-rot fungus Phanerochaete chrysosporium has been shown to degrade a variety of persistent environmental pollutants. Many of the enzymes responsible for pollutant degradation, which are normally involved in the degradation of wood, are extracellular. Thus, P. chrysosporium is able to degrade toxic or insoluble chemicals more efficiently than other microorganisms. P. chrysosporium has a range of oxidative and reductive mechanisms and uses highly reactive, nonspecific redox mediators which increase the number of chemicals that can be effectively degraded. This review gives an overview of the enzymes that are believed to be important for bioremediation and briefly discusses the degradation of some individual chemicals.Type of Medium: Electronic ResourceURL: -
8Van Aken, B. ; Cameron, M. D. ; Stahl, J. D. ; Plumat, A. ; Naveau, H. ; Aust, S. D. ; Agathos, S. N.
Springer
Published 2000Staff ViewISSN: 1432-0614Source: Springer Online Journal Archives 1860-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Abstract Manganese-dependent peroxidase (MnP) H5 from the white-rot fungus Phanerochaete chrysosporium, in the presence of either Mn(II) (10 mM) or GSH (10 mM), was able to mineralize 14C-U-ring-labeled 2-amino-4,6-dinitrotoluene (2-A-4,6-DNT) up to 29% in 12 days. When both Mn(II) and GSH were present, the mineralization extent reached 82%. On the other hand, no significant mineralization was observed in the absence of both Mn(II) and GSH, suggesting the requirement of a mediator [either Mn(II) or GSH] for the degradation of 2-A-4,6-DNT by MnP. Using electron spin resonance (ESR) techniques, it was found that the glutathionyl free radical (GS•) was produced through the oxidation of GSH by MnP in the presence as well as in the absence of Mn(II). GS• was also generated through the direct oxidation of GSH by Mn(III). Our results strongly suggest the involvement of GS• in the GSH-mediated mineralization of 2-A-4,6-DNT by MnP.Type of Medium: Electronic ResourceURL: