Search Results - (Author, Cooperation:M. Chan)
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1Latest Papers from Table of Contents or Articles in PressLindroth, H., Bratzke, L., Purvis, S., Brown, R., Coburn, M., Mrkobrada, M., Chan, M. T. V., Davis, D. H. J., Pandharipande, P., Carlsson, C. M., Sanders, R. D.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-04-29Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Geriatric medicine, Open access, Geriatric medicinePublished by: -
2Latest Papers from Table of Contents or Articles in PressAndrea D. Pickel; Ayelet Teitelboim; Emory M. Chan; Nicholas J. Borys; P. James Schuck; Chris Dames
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-11-22Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-1723Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralPhysicsPublished by: -
3Latest Papers from Table of Contents or Articles in PressElfar, W., Järvinen, E., Ji, W., Mosorin, J., Sega, A. G., Iuga, A. C., Lobritto, S. J., Konstantino, M., Chan, A., Finel, M., Lakhani, S. A.
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Published 2018Staff ViewPublication Date: 2018-12-12Publisher: The American Society for Pharmacology and Experimental Therapeutics (ASPET)Print ISSN: 0090-9556Electronic ISSN: 1521-009XTopics: Chemistry and PharmacologyMedicinePublished by: -
4Latest Papers from Table of Contents or Articles in PressZ. D. Smith ; M. M. Chan ; T. S. Mikkelsen ; H. Gu ; A. Gnirke ; A. Regev ; A. Meissner
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; CpG Islands/genetics ; *DNA Methylation/genetics ; Embryo, Mammalian/*embryology/*metabolism ; Embryonic Development/*genetics ; Female ; Fertilization/genetics ; Genome/genetics ; Long Interspersed Nucleotide Elements/genetics ; Male ; Mice ; Oocytes/metabolism ; Spermatozoa/metabolism ; Terminal Repeat Sequences/genetics ; Zygote/metabolismPublished by: -
5Latest Papers from Table of Contents or Articles in PressZ. D. Smith ; M. M. Chan ; K. C. Humm ; R. Karnik ; S. Mekhoubad ; A. Regev ; K. Eggan ; A. Meissner
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Blastocyst/*metabolism ; Cell Line ; CpG Islands/physiology ; DNA/metabolism ; *DNA Methylation ; Embryonic Stem Cells ; Female ; Gene Expression Regulation, Developmental ; Humans ; Male ; Mice ; Mice, Inbred C57BLPublished by: -
6Latest Papers from Table of Contents or Articles in PressA. Kaur ; M. R. Webster ; K. Marchbank ; R. Behera ; A. Ndoye ; C. H. Kugel, 3rd ; V. M. Dang ; J. Appleton ; M. P. O'Connell ; P. Cheng ; A. A. Valiga ; R. Morissette ; N. B. McDonnell ; L. Ferrucci ; A. V. Kossenkov ; K. Meeth ; H. Y. Tang ; X. Yin ; W. H. Wood, 3rd ; E. Lehrmann ; K. G. Becker ; K. T. Flaherty ; D. T. Frederick ; J. A. Wargo ; Z. A. Cooper ; M. T. Tetzlaff ; C. Hudgens ; K. M. Aird ; R. Zhang ; X. Xu ; Q. Liu ; E. Bartlett ; G. Karakousis ; Z. Eroglu ; R. S. Lo ; M. Chan ; A. M. Menzies ; G. V. Long ; D. B. Johnson ; J. Sosman ; B. Schilling ; D. Schadendorf ; D. W. Speicher ; M. Bosenberg ; A. Ribas ; A. T. Weeraratna
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-04-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Aging/*metabolism ; Animals ; Cell Line, Tumor ; Culture Media, Conditioned/pharmacology ; DNA Damage ; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism ; Disease Progression ; *Drug Resistance, Neoplasm ; Fibroblasts/secretion ; Humans ; Indoles/pharmacology/therapeutic use ; Male ; Melanoma/blood supply/*drug therapy/genetics/*pathology ; Membrane Proteins/*metabolism/secretion ; Mice ; Microphthalmia-Associated Transcription Factor/metabolism ; Middle Aged ; Molecular Targeted Therapy ; *Neoplasm Metastasis ; Neovascularization, Pathologic ; Oxidative Stress ; Phenotype ; Reactive Oxygen Species/metabolism ; Sulfonamides/pharmacology/therapeutic use ; *Tumor Microenvironment ; Wnt Signaling Pathway ; Wnt1 Protein/antagonists & inhibitors ; beta Catenin/metabolismPublished by: -
7Latest Papers from Table of Contents or Articles in PressUddin, M., Woodbury-Smith, M., Chan, A. J. S., Albanna, A., Minassian, B., Boelman, C., Scherer, S. W.
Genetics Society of America (GSA)
Published 2018Staff ViewPublication Date: 2018-03-29Publisher: Genetics Society of America (GSA)Electronic ISSN: 2160-1836Topics: BiologyPublished by: -
8Latest Papers from Table of Contents or Articles in PressAhmad, N. A., Silim, U. A., Rosman, A., Mohamed, M., Chan, Y. Y., Mohd Kasim, N., Yusof, M., Abd Razak, M. A., Omar, M., Abdul Aziz, F. A., Jamaluddin, R., Ismail, F., Ibrahim, N., Aris, T.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-05-16Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Mental healthPublished by: -
9Latest Papers from Table of Contents or Articles in PressLiye Zou; Albert Yeung; Xinfeng Quan; Stanley Sai-Chuen Hui; Xiaoyue Hu; Jessie S. M. Chan; Chaoyi Wang; Sean David Boyden; Li Sun; Huiru Wang
MDPI Publishing
Published 2018Staff ViewPublication Date: 2018-02-13Publisher: MDPI PublishingPrint ISSN: 1661-7827Electronic ISSN: 1660-4601Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicinePublished by: -
10Latest Papers from Table of Contents or Articles in PressM. Chan ; K. Kupferschmidt
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-10-31Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Anti-Bacterial Agents ; Drug Prescriptions/statistics & numerical data ; Drug Resistance, Microbial ; Hemorrhagic Fever, Ebola/epidemiology/prevention & control ; Humans ; Trust ; World Health Organization/*economics/*organization & administrationPublished by: -
11Latest Papers from Table of Contents or Articles in PressD. Singh ; J. M. Chan ; P. Zoppoli ; F. Niola ; R. Sullivan ; A. Castano ; E. M. Liu ; J. Reichel ; P. Porrati ; S. Pellegatta ; K. Qiu ; Z. Gao ; M. Ceccarelli ; R. Riccardi ; D. J. Brat ; A. Guha ; K. Aldape ; J. G. Golfinos ; D. Zagzag ; T. Mikkelsen ; G. Finocchiaro ; A. Lasorella ; R. Rabadan ; A. Iavarone
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-07-28Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Aneuploidy ; Animals ; Antineoplastic Agents/pharmacology ; Benzamides/pharmacology ; Brain Neoplasms/genetics/metabolism ; *Cell Transformation, Neoplastic ; Chromosomal Instability ; Enzyme Inhibitors/pharmacology ; Fetal Proteins/chemistry/*genetics/metabolism ; Glioblastoma/*genetics/metabolism ; Humans ; Mice ; Microtubule-Associated Proteins/chemistry/*genetics/metabolism ; Mitosis ; Neoplasm Transplantation ; Nuclear Proteins/chemistry/*genetics/metabolism ; Oncogene Fusion ; Oncogene Proteins, Fusion/chemistry/genetics/*metabolism ; Piperazines/pharmacology ; Protein Structure, Tertiary ; Pyrazoles/pharmacology ; Pyrimidines/pharmacology ; Receptor, Fibroblast Growth Factor, Type 1/antagonists & ; inhibitors/chemistry/*genetics/metabolism ; Receptor, Fibroblast Growth Factor, Type 3/antagonists & ; Spindle Apparatus/metabolism ; Translocation, Genetic ; Xenograft Model Antitumor AssaysPublished by: -
12Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2011-07-02Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Ethics, Institutional ; *Global Health ; Humans ; *World Health OrganizationPublished by: -
13Latest Papers from Table of Contents or Articles in PressR. Possemato ; K. M. Marks ; Y. D. Shaul ; M. E. Pacold ; D. Kim ; K. Birsoy ; S. Sethumadhavan ; H. K. Woo ; H. G. Jang ; A. K. Jha ; W. W. Chen ; F. G. Barrett ; N. Stransky ; Z. Y. Tsun ; G. S. Cowley ; J. Barretina ; N. Y. Kalaany ; P. P. Hsu ; K. Ottina ; A. M. Chan ; B. Yuan ; L. A. Garraway ; D. E. Root ; M. Mino-Kenudson ; E. F. Brachtel ; E. M. Driggers ; D. M. Sabatini
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-07-16Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/enzymology/*genetics/*metabolism/pathology ; Cell Line, Tumor ; Cell Proliferation ; Citric Acid Cycle/physiology ; Gene Expression Regulation, Enzymologic ; Gene Expression Regulation, Neoplastic ; *Genomics ; Glutamic Acid/metabolism ; Humans ; Ketoglutaric Acids/metabolism ; Melanoma/enzymology/genetics ; Mice ; Neoplasm Transplantation ; Phosphoglycerate Dehydrogenase/genetics/metabolism ; RNA Interference ; Serine/*biosynthesisPublished by: -
14Latest Papers from Table of Contents or Articles in PressY. Nakamura ; J. Oscherwitz ; K. B. Cease ; S. M. Chan ; R. Munoz-Planillo ; M. Hasegawa ; A. E. Villaruz ; G. Y. Cheung ; M. J. McGavin ; J. B. Travers ; M. Otto ; N. Inohara ; G. Nunez
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-11-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacterial Toxins/*metabolism/pharmacology ; Calcium Signaling/drug effects ; *Cell Degranulation/drug effects ; Culture Media, Conditioned/pharmacology ; Dermatitis, Atopic/immunology/metabolism/*microbiology/pathology ; Female ; Immunoglobulin E/biosynthesis/immunology ; Inflammation/immunology/metabolism/microbiology/pathology ; Interleukin-4/immunology ; Intracellular Signaling Peptides and Proteins/metabolism ; Male ; Mast Cells/*cytology/drug effects ; Mice ; Phosphatidylinositol 3-Kinases/metabolism ; Protein-Tyrosine Kinases/metabolism ; Proto-Oncogene Proteins c-kit/genetics/metabolism ; Staphylococcus aureus/metabolism/*pathogenicityPublished by: -
15Articles: DFG German National LicensesStaff View
ISSN: 1365-2222Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Occupational asthma due to Western Red Cedar (WRCA) is attributed to sensitization to plicatic acid (PA), but does not appear to be dependent on PA-specific IgE antibodies. Exposure to PA induces histamine release in vivo and in vitro, so if IgE is not important. other mechanisms of histamine release must presumably operate in WRCA, To explore the possible role of histamine-releasing factors in WRCA, peripheral blood mono-nuclear cells were obtained and cultured with PA, PA-albumin conjugate plica tic acid-human serum albumin (PA-HSA).grass pollen or Concanavalin A using a standard histamine releasing factor (HRF) generation protocol. Supernatants were dialysed to remove endogenous histamine and then assayed for histamine releasing activity using human basophils as targets and a Con A-induced bulk supernatant as an internal HRF standard. In contrast to some previous reports, spontaneous HRF release from the peripheral blood mononuclear cells (PBMC) of WRCA patients (n= 9) and atopic asthmatic subjects (n= 5) was not elevated compared with the non-asthmatic controls (n= 11; five atopic and six non-atopic). Both PA and PA-HSA induced the production of small amounts of HRF by PBMC of WRCA patients, but a similar degree of HRF generation was also observed in PBMC from the atopic asthmatic, atopic non-aslhmatic, and non-atopic subjects. The contrast, grass pollen induced the production of HRF by PBMC from the subjects with positive skin tests to grass pollen but not by PBMC of non-atopic subjects, confirming that our methods and assay were capable of detecting antigen-specific HRF production. Since neither PA nor PA-HSA induced significantly elevated HRF production from PBMC of WRCA patients, it seems unlikely that PA-induced HRFs play a substantial role in the pathogenesis of WRCA.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1365-2222Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: In order to investigate the relationship between the pattern of response (immediate, late and dual) to specific bronchial challenge test with plicatic acid or red cedar extract and the clinical features of asthma, 332 patients with-asthma induced by western red cedar dust were examined at the time of diagnosis. Specific challenge test induced in thirty-one patients (9.3%) an isolated immediate reaction, in 144 patients (43.4%) an isolated late reaction and in 157 patients (47.3%) a dual reaction. Patients with a dual reaction had a longer period of exposure to red cedar dust between the onset of the respiratory symptoms and the time of the definitive diagnosis, a lower FEF 25–75% and a greater degree of non-specific bronchial hyperresponsiveness compared to patients with isolated immediate or isolated late reactions; the difference in bronchial hyperresponsiveness to methacholine among the three groups persisted when the values were adjusted for the different baseline value of FEV1. There was no difference in the prevalence of specific serum IgE antibodies to plicatic acid-human serum albumin conjugate among the three groups of patients with different type of response to red cedar. Except for the greater degree of non-specific bronchial hyperresponsiveness, patients with isolated late reactions were not different from those with isolated immediate reactions in other clinical findings. These findings indicate that a dual reaction in patients with occupational asthma due to simple chemical agents is indicative of a greater severity of disease at diagnosis. The pathogenetic mechanism of various types of asthmatic reaction is unknown and it is likely to be different between isolated immediate and isolated late reactions.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesCHAN, M. T. V. ; CHAN, M. S. H. ; MUI, K. S. Y. ; HO, B. P. Y.
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We report a case of upper airway obstruction as a result of delayed massive lingual swelling following routine cleft palate repair in an otherwise healthy 12-month-old girl. We believe that ischaemia and venous congestion were the causes of macroglossia, after prolonged use of the Digman Dott tongue retractor. In any difficult and lengthy repair, we recommend the prophylactic insertion of a nasopharyngeal airway under direct vision by the surgeons after surgery to prevent potential upper airway obstruction.Type of Medium: Electronic ResourceURL: -
18Latest Papers from Table of Contents or Articles in PressWang, X., Zhang, X., Chu, E. S. H., Chen, X., Kang, W., Wu, F., To, K.-F., Wong, V. W. S., Chan, H. L. Y., Chan, M. T. V., Sung, J. J. Y., Wu, W. K. K., Yu, J.
The Federation of American Societies for Experimental Biology (FASEB)
Published 2018Staff ViewPublication Date: 2018-01-03Publisher: The Federation of American Societies for Experimental Biology (FASEB)Print ISSN: 0892-6638Electronic ISSN: 1530-6860Topics: BiologyPublished by: -
19Latest Papers from Table of Contents or Articles in PressZuo, T., Wong, S. H., Lam, K., Lui, R., Cheung, K., Tang, W., Ching, J. Y. L., Chan, P. K. S., Chan, M. C. W., Wu, J. C. Y., Chan, F. K. L., Yu, J., Sung, J. J. Y., Ng, S. C.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-03-09Publisher: BMJ Publishing GroupPrint ISSN: 0017-5749Electronic ISSN: 1468-3288Topics: MedicineKeywords: Open access, Editor's choicePublished by: -
20Latest Papers from Table of Contents or Articles in PressZhao, W., Li, M., Chang, C.-Z., Jiang, J., Wu, L., Liu, C., Moodera, J. S., Zhu, Y., Chan, M. H. W.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-03-17Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: