Search Results - (Author, Cooperation:M. Canals)
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1P. Puig ; M. Canals ; J. B. Company ; J. Martin ; D. Amblas ; G. Lastras ; A. Palanques
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-09-07Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Agriculture/methods ; Animals ; Aquatic Organisms/*physiology ; *Ecosystem ; Fisheries/economics/*methods ; Fishes/physiology ; *Geography ; Geologic Sediments/*analysis/chemistry ; Human Activities ; *Marine Biology ; Oceans and Seas ; Seawater/chemistry ; Time FactorsPublished by: -
2R. O. Dror ; H. F. Green ; C. Valant ; D. W. Borhani ; J. R. Valcourt ; A. C. Pan ; D. H. Arlow ; M. Canals ; J. R. Lane ; R. Rahmani ; J. B. Baell ; P. M. Sexton ; A. Christopoulos ; D. E. Shaw
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-10-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Allosteric Regulation/physiology ; Animals ; Binding Sites ; CHO Cells ; Cricetulus ; *Drug Design ; Humans ; Models, Chemical ; Molecular Conformation ; Molecular Dynamics Simulation ; Mutation ; Protein Binding ; Receptors, G-Protein-Coupled/*antagonists & inhibitors/*chemistry/genetics ; Reproducibility of ResultsPublished by: -
3Livingston, K. E., Stanczyk, M. A., Burford, N. T., Alt, A., Canals, M., Traynor, J. R.
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Published 2018Staff ViewPublication Date: 2018-01-13Publisher: The American Society for Pharmacology and Experimental Therapeutics (ASPET)Print ISSN: 0026-895XElectronic ISSN: 1521-0111Topics: Chemistry and PharmacologyMedicinePublished by: -
4Lastras, G. ; Canals, M. ; Urgeles, R. ; Hughes-Clarke, J. E. ; Acosta, J.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-3091Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: GeosciencesNotes: Four slides, the Ana, Joan, Nuna and Jersi slides, have been imaged on the seafloor along the Balearic margin of the Eivissa Channel in the western Mediterranean. They have areas of up to 16 km2 and occur in water depths ranging between 600 and 900 m. Volumes range from 0·14 to 0·4 km3. Their headwall scarps, internal architecture and associated deposits are characterized using a combination of swath bathymetry data and very high-resolution seismic reflection profiles. In general, they show horseshoe-shaped headwall scarps and distinct depositional lobes with positive relief. Internally, the slide bodies are mostly composed of transparent seismic facies. Chaotic facies are observed at the toe of some of the slides, and blocks of coherent stratified facies embedded in the slide deposit have also been identified. The reflection profiles demonstrate that the four slides share the same slip horizon, which corresponds to a distinctive continuous, high-amplitude reflector. Furthermore, the geometry of the headwall scars of the Nuna and Ana slides reveals evidence of pockmarks, and fluid escape features are also present further upslope. This indicates a possible link between fluid escape features and destabilization of the upper sediment layers. In addition, these well-characterized slides demonstrate the pitfalls associated with calculating the volume of the slide masses using headwall scarp heights and the assumed preslide seafloor topography in the absence of seismic data. The internal structure also demonstrates that transport distances within the slides are generally low and poorly characterized by headwall scarp to slide toe lengths.Type of Medium: Electronic ResourceURL: -
5TORRES, J. ; DROZ, L. ; SAVOYE, B. ; TERENTIEVA, E. ; COCHONAT, P. ; KENYON, N. H. ; CANALS, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1997Staff ViewISSN: 1365-3091Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: GeosciencesNotes: The Petit-Rhône Fan Valley (north-western Mediterranean) is a broad, sinuous, filled valley that is deeply incised by a narrow, sinuous thalweg. The valley fill is differentiated into three seismic subunits on high-resolution seismic-reflection profiles. The lower chaotic subunit probably consists of channel lag deposits that seem to be in lateral continuity with high-amplitude reflections representing levee facies. The intermediate transparent subunit, which has an erosional base and clearly truncates levee deposits, is interpreted to be mass-flow deposits resulting from the disintegration of the fan-valley flanks. The upper bedded subunit shows an overall lens-shaped geometry and the seismic reflections onlap either onto the top of the underlying transparent subunit or onto the Rhône levees. Piston core data show that the upper few meters of this upper subunit consist of thin turbidites, probably deposited by overflow processes. The few available 14C ages suggest that the upper stratified subunit filled the Petit-Rhône Fan Valley between 21 and 11 kyr BP.The upper bedded subunit is deposited within the Petit-Rhône Fan Valley downslope of a major decrease in slope gradient. This upper subunit and the thalweg are genetically related and represent a small channel/levee system confined within the fan valley. Previous studies interpreted this thalweg to be an erosional feature resulting from a recent avulsion of the major channel course. Our interpretation implies that the thalweg is not a purely erosional feature but a depositional/erosional channel. This small channel/levee system is superimposed on a large muddy channel/levee system after the sediment supply changed from thick muddy flows during the main phase of aggradation of the Rhône Fan levees, to thin, mixed (sand and mud) flows at the end of Isotope Stage 2 (∼16–18 ka BP). The pre-existing morphology of the Petit-Rhône Fan Valley played a determinant role in the sediment dispersal leading to the creation of this small and confined channel/levee system. These mixed flows have undergone flow stripping resulting from the changes in the slope gradient along the thalweg course. The finer sediment overflowed from the thalweg and were deposited in the Petit-Rhône Fan Valley. Coarser channelled sediment remaining in the thalweg were deposited as a ‘sandy’lobe (Neofan). As indicated by 14C dating, sedimentation on this lobe continued until very recently, suggesting a further evolution of the turbidity flows from small mixed flows to small sandy flows. the deposition of this study lobe and the sedimentary fill of the Petit-Rhône Fan Valley may be related to widespread shelf edge and canyon wall failures with a resulting downslope evolution of failed sediment into turbidity currents.Type of Medium: Electronic ResourceURL: -
6Merindano, M. D. ; Canals, M. ; Potau, J. M. ; Costa, J. ; Ruano, D.
Oxford, UK : Blackwell Publishing Ltd
Published 1998Staff ViewISSN: 1439-0264Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The study has been conducted on 40 species of mammals included in different taxonomic orders: 10 carnivores (felines and canides), 13 primates and 17 herbivores (artiodactyles, perisodactyles and proboscideans). Domestic, experimental and wild animals have been included in the sample.The purpose of the study is to offer new data regarding morphometric aspects of the epithelium of the cornea of mammals. We also aim to establish the relationships and differences between the different epithelia studied and to determine the morphometric characteristics which best define the epithelium of the different species under study.The results obtained have demonstrated the existence of correlations between thicknesses, number of cellular layers and number of the epithelial cells in the different groups. It has also been established that the variants in thickness and number of layers define and characterize the epithelia. Finally, the study reveals that morphometric characteristics of the epithelium of primates and carnivores have more similarities than those of herbivores.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0022-5193Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: