Search Results - (Author, Cooperation:M. Bunce)

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  1. 1
    M. Rasmussen ; X. Guo ; Y. Wang ; K. E. Lohmueller ; S. Rasmussen ; A. Albrechtsen ; L. Skotte ; S. Lindgreen ; M. Metspalu ; T. Jombart ; T. Kivisild ; W. Zhai ; A. Eriksson ; A. Manica ; L. Orlando ; F. M. De La Vega ; S. Tridico ; E. Metspalu ; K. Nielsen ; M. C. Avila-Arcos ; J. V. Moreno-Mayar ; C. Muller ; J. Dortch ; M. T. Gilbert ; O. Lund ; A. Wesolowska ; M. Karmin ; L. A. Weinert ; B. Wang ; J. Li ; S. Tai ; F. Xiao ; T. Hanihara ; G. van Driem ; A. R. Jha ; F. X. Ricaut ; P. de Knijff ; A. B. Migliano ; I. Gallego Romero ; K. Kristiansen ; D. M. Lambert ; S. Brunak ; P. Forster ; B. Brinkmann ; O. Nehlich ; M. Bunce ; M. Richards ; R. Gupta ; C. D. Bustamante ; A. Krogh ; R. A. Foley ; M. M. Lahr ; F. Balloux ; T. Sicheritz-Ponten ; R. Villems ; R. Nielsen ; J. Wang ; E. Willerslev
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-09-24
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    African Continental Ancestry Group ; Animals ; Asia ; Asian Continental Ancestry Group/genetics ; Computer Simulation ; DNA, Mitochondrial/genetics ; Emigration and Immigration ; Ethnic Groups/genetics ; European Continental Ancestry Group/genetics ; Far East ; Gene Flow ; Gene Frequency ; Genetics, Population/methods ; *Genome, Human ; Genome, Mitochondrial ; Haplotypes ; Hominidae/genetics ; Humans ; Linkage Disequilibrium ; Male ; Oceanic Ancestry Group/*genetics ; Phylogeny ; Polymorphism, Single Nucleotide ; Sequence Analysis, DNA ; Western Australia
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    E. D. Jarvis ; S. Mirarab ; A. J. Aberer ; B. Li ; P. Houde ; C. Li ; S. Y. Ho ; B. C. Faircloth ; B. Nabholz ; J. T. Howard ; A. Suh ; C. C. Weber ; R. R. da Fonseca ; J. Li ; F. Zhang ; H. Li ; L. Zhou ; N. Narula ; L. Liu ; G. Ganapathy ; B. Boussau ; M. S. Bayzid ; V. Zavidovych ; S. Subramanian ; T. Gabaldon ; S. Capella-Gutierrez ; J. Huerta-Cepas ; B. Rekepalli ; K. Munch ; M. Schierup ; B. Lindow ; W. C. Warren ; D. Ray ; R. E. Green ; M. W. Bruford ; X. Zhan ; A. Dixon ; S. Li ; N. Li ; Y. Huang ; E. P. Derryberry ; M. F. Bertelsen ; F. H. Sheldon ; R. T. Brumfield ; C. V. Mello ; P. V. Lovell ; M. Wirthlin ; M. P. Schneider ; F. Prosdocimi ; J. A. Samaniego ; A. M. Vargas Velazquez ; A. Alfaro-Nunez ; P. F. Campos ; B. Petersen ; T. Sicheritz-Ponten ; A. Pas ; T. Bailey ; P. Scofield ; M. Bunce ; D. M. Lambert ; Q. Zhou ; P. Perelman ; A. C. Driskell ; B. Shapiro ; Z. Xiong ; Y. Zeng ; S. Liu ; Z. Li ; B. Liu ; K. Wu ; J. Xiao ; X. Yinqi ; Q. Zheng ; Y. Zhang ; H. Yang ; J. Wang ; L. Smeds ; F. E. Rheindt ; M. Braun ; J. Fjeldsa ; L. Orlando ; F. K. Barker ; K. A. Jonsson ; W. Johnson ; K. P. Koepfli ; S. O'Brien ; D. Haussler ; O. A. Ryder ; C. Rahbek ; E. Willerslev ; G. R. Graves ; T. C. Glenn ; J. McCormack ; D. Burt ; H. Ellegren ; P. Alstrom ; S. V. Edwards ; A. Stamatakis ; D. P. Mindell ; J. Cracraft ; E. L. Braun ; T. Warnow ; W. Jun ; M. T. Gilbert ; G. Zhang
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-12-17
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Avian Proteins/genetics ; Base Sequence ; Biological Evolution ; Birds/classification/*genetics ; DNA Transposable Elements ; Genes ; Genetic Speciation ; *Genome ; INDEL Mutation ; Introns ; *Phylogeny ; Sequence Analysis, DNA
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Mallon, E. ; Bunce, M. ; Savoie, H. ; Rowe, A. ; Newson, R. ; Gotch, F. ; Bunker, C.B.

    Oxford, UK : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background Psoriasis is a heterogeneous disease in its clinical expression. Both genetic and environmental factors are thought to contribute to the pathogenesis of the inflammatory and hyperproliferative components of the typical skin lesions. Predisposing genetic influences include associations with human leucocyte antigens (HLA) of which that with HLA-Cw6 is the strongest. Guttate psoriasis is a specific clinical manifestation of psoriasis frequently associated with group A β-haemolytic streptococcal throat infection. Objectives We set out to determine whether further clinical subdivision of psoriasis is associated with tighter correlation with HLA-C alleles. Patients/methods We determined the HLA-C locus genotype of 29 caucasian patients with guttate psoriasis presenting consecutively with guttate psoriasis associated with a history of a sore throat and/or an antistreptolysin O titre 〉 200 IU mL−1. Polymerase chain reaction typing using sequence-specific primers was used to detect all known HLA-C alleles. These data were compared with a control population of 604 random caucasian cadaver donors. Results All patients (100%) with guttate psoriasis carried the Cw*0602 allele compared with 20% of the control population (odds ratio = ∞; 95% confidence limits 25·00–∞; Pcorrected 〈 0·0000002). Conclusions This result is consistent with HLA-Cw*0602 playing a part directly in the pathogenesis of guttate psoriasis.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2133.2000.03885.x

    Articles: DFG German National Licenses
  4. 4
    Ahmad, T. ; Satsangi, J. ; Mcgovern, D. ; Bunce, M. ; Jewell, D. P.

    Oxford UK : Blackwell Science Ltd
    Published 2001
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Recent epidemiological, clinical and molecular studies have provided strong evidence that inherited predisposition is important in the pathogenesis of chronic inflammatory bowel diseases. The model most consistent with the epidemiological data suggests that Crohn’s disease and ulcerative colitis are related polygenic diseases, sharing some but not all susceptibility genes. Investigators throughout the world have applied the complementary techniques of genome-wide scanning and candidate gene analysis. Four areas of linkage have been widely replicated on chromosomes 16 (IBD1), 12 (IBD2), 6 (IBD3—the HLA region), and most recently on chromosome 14. Fine mapping of these regions is underway. Of the ‘positional’ candidate genes, most attention has centred on the genes of the major histocompatibility complex. Genes within this region may determine disease susceptibility, behaviour, complications and response to therapy. Hope continues that studies of inflammatory bowel disease genetics will provide fresh insight into disease pathogenesis and soon deliver clinical applications.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2036.2001.00981.x

    Articles: DFG German National Licenses
  5. 5
    MARREN, P. ; JELL, J. ; CHARNOCK, F.M. ; BUNCE, M. ; WELSH, K. ; WOJNAROWSKA, F.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Although frequently linked clinically with autoimmune disease, no immunogenetic basis for lichen sclerosus has ever been established. In this study, we examined in detail the HLA antigens of 84 patients with histologically proven disease, compared with 357 controls. Patients with lichen sclerosus did not have the expected HLA A1, B8, DR3, DQ2 autoimmune profile. Instead, DQ7 was present in 39 of 78 (50%) of patients compared with 89 (25%) controls (P 〈0.001). In addition, 61 of 78 patients (78%) had either DQ7, DQ8 or DQ9 antigens, or a combination of these, compared with 142 (40%) controls (P 〈 0.01). Raised levels of DQ7 correspond to a glutamic acid residue at position 45 of the DQB1 locus. Proline amino acids at position 55 of this DQB1 locus could explain the raised levels of DQ7, 8 and 9, and exert a secondary effect. There is preliminary evidence that the immunogenetic profile of patients with this disease may affect disease expression with regard to site and extent of involvement.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2133.1995.tb05013.x

    Articles: DFG German National Licenses
  6. 6
    Bunce, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0743-0167
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Geography
    Economics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0743-0167(86)90054-9

    Articles: DFG German National Licenses
  7. 7
    Curran, M. D. ; Williams, F. ; Earle, J. A. P. ; Rima, B. K. ; Dam, M. G. ; Bunce, M. ; Middleton, D.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1744-313X
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    We have developed a simple, rapid and reliable method for specifically amplifying and cloning full-length HLA-B genes from genomic DNA. Using this methodology we characterized three alleles of interest at the molecular level. Two of the alleles appeared in our routine class I PCR-SSOP typing system, a variant of B*5801 found in the Daudi cell line and RCE 56 and a variant of B*4101 found in a number of volunteer donors on our Bone Marrow Donor Registry. The third, a variant B35 allele found in RCE 80, was first identified as unusual by serology. Our sequencing analysis of exon 2 and exon 3 identified two of these alleles as the recently reported novel HLA-B*5802 and HLA-B*4102 alleles, while the third represents a new B35 allele officially designated B*3513.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1744-313X.1996.tb00125.x

    Articles: DFG German National Licenses
  8. 8
    Lister, A. M. ; Edwards, C. J. ; Nock, D. A. W. ; Bunce, M. ; van Pijlen, I. A. ; Bradley, D. G. ; Thomas, M. G. ; Barnes, I.

    [s.l.] : Nature Publishing Group
    Published 2005
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] The giant deer, or ‘Irish elk’, has featured extensively in debates on adaptation, sexual selection, and extinction. Its huge antlers—the largest of any deer species, living or extinct—formed a focus of much past work. Yet the phylogenetic position of the giant deer ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/nature04134

    Articles: DFG German National Licenses