Search Results - (Author, Cooperation:M. Brueckner)

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  1. 1
    Staff View
    Publication Date:
    2018-01-24
    Publisher:
    Institute of Physics Publishing (IOP)
    Electronic ISSN:
    1748-0221
    Topics:
    Physics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-01-31
    Publisher:
    Institute of Physics Publishing (IOP)
    Electronic ISSN:
    1748-0221
    Topics:
    Physics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-01-27
    Publisher:
    Institute of Physics Publishing (IOP)
    Electronic ISSN:
    1748-0221
    Topics:
    Physics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-11-13
    Publisher:
    Institute of Physics Publishing (IOP)
    Electronic ISSN:
    1748-0221
    Topics:
    Physics
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2016-01-20
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Brain/abnormalities/metabolism ; Child ; Congenital Abnormalities/genetics ; Exome/genetics ; Heart Defects, Congenital/*diagnosis/*genetics ; Humans ; Mutation ; Nervous System Malformations/*genetics ; Neurogenesis/*genetics ; Prognosis ; RNA Splicing/genetics ; RNA, Messenger/genetics ; RNA-Binding Proteins/genetics ; Repressor Proteins/genetics ; Transcription, Genetic
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2013-05-15
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adult ; Case-Control Studies ; Child ; Chromatin/chemistry/metabolism ; DNA Mutational Analysis ; Enhancer Elements, Genetic/genetics ; Exome/genetics ; Female ; Genes, Developmental/genetics ; Heart Diseases/*congenital/*genetics/metabolism ; Histones/chemistry/*metabolism ; Humans ; Lysine/chemistry/metabolism ; Male ; Methylation ; Mutation ; Odds Ratio ; Promoter Regions, Genetic/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    M. T. Boskovski ; S. Yuan ; N. B. Pedersen ; C. K. Goth ; S. Makova ; H. Clausen ; M. Brueckner ; M. K. Khokha
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-11-15
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    ADAM Proteins/metabolism ; Amino Acid Sequence ; Animals ; *Body Patterning ; Cilia/metabolism/*physiology ; Embryo, Nonmammalian/embryology/metabolism ; Glycosylation ; Heterotaxy Syndrome/*genetics ; Humans ; Mice ; Molecular Sequence Data ; N-Acetylgalactosaminyltransferases/deficiency/genetics/*metabolism ; Peptide Fragments/chemistry/metabolism ; Receptor, Notch1/chemistry/deficiency/genetics/*metabolism ; *Signal Transduction ; Xenopus/embryology/genetics ; Xenopus Proteins/deficiency/genetics/*metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Brückner, M. ; Schäfer, J. H. ; Schiffer, C. ; Uhlenbusch, J.

    [S.l.] : American Institute of Physics (AIP)
    Published 1991
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The index of refraction, the extinction coefficient, and the absorptance for gold and tin were measured in a temperature range from room temperature up to the melting point for the wavelength λ=10.6 μm. All measurements were performed under ultrahigh-vacuum conditions using a photometric infrared ellipsometer with a rotating analyzer. Measurements verify a discontinuous jump of the absorptance at the solid-to-liquid phase transition from 3.5 to 6.5% in the case of gold and from 4.9 to 9.2% in the case of tin. The experimental results derived for the clean solid surface are in good agreement with the theoretical prediction by a Drude model, if additionally appropriate effective masses and the anomalous skin effect are taken into account. This theory is much less accurate if applied to the molten state of gold and tin, as was already shown previously for liquid aluminum and copper.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.349530

    Articles: DFG German National Licenses
  9. 9
    Brückner, M. ; Schäfer, J. H. ; Uhlenbusch, J.

    [S.l.] : American Institute of Physics (AIP)
    Published 1989
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The index of refraction, the extinction coefficient, and the absorptance were measured under ultrahigh vacuum conditions in a temperature range from 295 to 1000 K for aluminum and from 295 to 1400 K for copper for the CO2 laser wavelength at λ=10.6 μm. A photometric infrared ellipsometer was applied. The absorptance of the clean metallic surfaces jumps discontinuously from 3% to 7% in the case of aluminum and from 2% to 6% in the case of copper at the melting point. Calculations of the optical constants basing on the model of free electrons taking account of the effective mass and the anomalous skin effect describe the measurements for the solid state very well, but are less accurate for the molten state.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.344431

    Articles: DFG German National Licenses
  10. 10
    McGrath, J. ; Horwich, A.L. ; Brueckner, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0888-7543(05)80163-6

    Articles: DFG German National Licenses
  11. 11
    McGrath, J. ; Horwich, A.L. ; Brueckner, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0888-7543(05)80163-6

    Articles: DFG German National Licenses
  12. 12
    Arendt, T. ; Holzer, M. ; Gertz, H.-J. ; Brückner, M. K.
    Springer
    Published 1999
    Staff View
    ISSN:
    1435-1463
    Keywords:
    Keywords: Alzheimer's disease ; cholinergic system ; degeneration ; phosphorylation ; tau.
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary. To assess a potential relationship between cortical neurofibrillary degeneration and cortical cholinergic deafferentation, the load of PHF-tau was analysed in eight cortical regions and in the basal nucleus of Meynert in 12 cases with Alzheimer's disease by means of a sensitive ELISA employing the monoclonal antibody B5-2. The activity of choline acetyltransferase was determined on identical tissue samples. The results demonstrate a highly correlative relationship between the cortical distribution of the amount of PHF-tau, mainly present in neuropil threads, and cholinergic depletion early during the course of the disease. This relationship was less strong in more advanced stages. The results support the suggestion that the formation of PHF-tau in cholinergic axon terminals which might result in a loss of cholinergic synapses and a cholinergic dysconnection of the cortex, is an early event in AD. During the progression of the disease, formation of PHF-tau appears to spread over the cortex which results in a more even distribution of neuropil threads and a progressive involvement of non-cholinergic neurons.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s007020050175

    Articles: DFG German National Licenses
  13. 13
    Guthmann, H. ; Brückner, M. A. ; Ehrenstein ; Wagner, H.
    Springer
    Published 1931
    Staff View
    ISSN:
    1432-0711
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01812668

    Articles: DFG German National Licenses
  14. 14
    Brückner, M. A.
    Springer
    Published 1933
    Staff View
    ISSN:
    1432-0711
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01726266

    Articles: DFG German National Licenses
  15. 15
    Brueckner, M. ; D'Eustachio, P. ; Horwich, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0168-9525
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0168-9525(89)90134-0

    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    1432-2218
    Keywords:
    Pericardial window ; Thoracoscopy ; Pericardial effusion
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract A patient suffered from recurrent pericardial effusions following heart transplantation. Repeated pericardiocentesis and insertion of pericardial drains could not resolve the problem and therefore surgical intervention was necessary. The procedure was performed as a minimally invasive thoracoscopic pericardial fenestration. Four months postoperative the patient was without recurrences. This method of pericardial fenestration after heart transplantation has been used for the first time.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00187170

    Articles: DFG German National Licenses
  17. 17
    Brückner, M. ; Grimm, H. ; Nam, V. C. ; Soehendra, N.
    Springer
    Published 1990
    Staff View
    ISSN:
    1432-2218
    Keywords:
    Pancreatic abscess ; Endoscopic treatment ; Nasopancreatic catheter ; Fibrin sealing
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary We present a case report of a patient with two large pancreatic abscesses and an associated colonic fistula originating from acute gallstone pancreatitis, which we treated endoscopically. The common bile duct stones were extracted after a papillotomy. The abscess in the pancreatic head was drained into the duodenum and the one in the pancreatic tail irrigated through a nasopancreatic catheter using normal saline mixed with gentamycin. The colonic fistula was finally obliterated using a two-component fibrin glue.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00316799

    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    1435-1463
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01281162

    Articles: DFG German National Licenses
  19. 19
    Bigl, M. ; Brückner, M. K. ; Arendt, T. ; Bigl, V. ; Eschrich, K.
    Springer
    Published 1999
    Staff View
    ISSN:
    1435-1463
    Keywords:
    Keywords: Alzheimer's disease ; glycolysis ; 6-phosphofructokinase ; glial fibrillary acidic protein.
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary. The activities of hexokinase, aldolase, pyruvate kinase, lactate dehydrogenase and glucose 6-phosphate dehydrogenase were determined in brains of patients with Alzheimer's disease (AD) and in age matched controls. For pyruvate kinase and lactate dehydrogenase a significant increase in specific activity was found in frontal and temporal cortex of AD brains, while the activities of aldolase and hexokinase are not changed. Glucose 6-phosphate dehydrogenase activity was significantly reduced in hippocampus. The increase of some glycolytic enzyme activities is correlated with increased contents of lactate dehydrogenase and glial fibrillary acidic protein (GFAP) in homogenates of frontal and temporal cortex and elevated phosphofructokinase (PFK) and GFAP in astrocytes from the same brain areas. The data extend previous findings on an increase in brain PFK specific activity in AD and suggest that the increased activity of some glycolytic enzymes may be, at least in part, the result of the reactive astrocytosis developing in the course of AD.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s007020050174

    Articles: DFG German National Licenses
  20. 20
    Holzer, M. ; Brückner, M. K. ; Beck, M. ; Bigl, V. ; Arendt, T.
    Springer
    Published 2000
    Staff View
    ISSN:
    1435-1463
    Keywords:
    Keywords: Primary guinea pig neurons, okadaic acid, metabolic labelling, amyloid precursor protein, Aβ peptide, Alzheimer's disease, DNA fragmentation.
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary. Primary cultures of guinea pig neurons were used as a model system to study the influence of the protein phosphatase inhibitor okadaic acid (OA) on the secretion, processing and phosphorylation of the amyloid precursor protein (APP). This primary cell culture system mimics more closely than other cell culture systems the human in vivo condition, as guinea pig APP is 98% homologous to human APP at the protein level, identical regarding the Aβ sequence and is processed in a similar manner as human APP. Both intracellular and secreted APP was upregulated by OA treatment (0.3 nM–10 nM) of 14 days old cultures in a concentration dependent manner while the amount of Aβ in the medium was decreased. OA treatment did not affect cell membrane integrity of primary neurons but induced DNA fragmentation. Phosphorylation of APP was unchanged by the low OA concentration used. These results show that OA treatment of guinea pig primary cultures might be used as a model to study the effects of modulation of signal transduction on secretion and processing of APP.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s007020070087

    Articles: DFG German National Licenses