Search Results - (Author, Cooperation:M. Barron)
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1T. F. Mackay ; S. Richards ; E. A. Stone ; A. Barbadilla ; J. F. Ayroles ; D. Zhu ; S. Casillas ; Y. Han ; M. M. Magwire ; J. M. Cridland ; M. F. Richardson ; R. R. Anholt ; M. Barron ; C. Bess ; K. P. Blankenburg ; M. A. Carbone ; D. Castellano ; L. Chaboub ; L. Duncan ; Z. Harris ; M. Javaid ; J. C. Jayaseelan ; S. N. Jhangiani ; K. W. Jordan ; F. Lara ; F. Lawrence ; S. L. Lee ; P. Librado ; R. S. Linheiro ; R. F. Lyman ; A. J. Mackey ; M. Munidasa ; D. M. Muzny ; L. Nazareth ; I. Newsham ; L. Perales ; L. L. Pu ; C. Qu ; M. Ramia ; J. G. Reid ; S. M. Rollmann ; J. Rozas ; N. Saada ; L. Turlapati ; K. C. Worley ; Y. Q. Wu ; A. Yamamoto ; Y. Zhu ; C. M. Bergman ; K. R. Thornton ; D. Mittelman ; R. A. Gibbs
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-02-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Animals ; Centromere/genetics ; Chromosomes, Insect/genetics ; Drosophila melanogaster/*genetics ; *Genome-Wide Association Study ; *Genomics ; Genotype ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/*genetics ; Selection, Genetic/genetics ; Starvation/genetics ; Telomere/genetics ; X Chromosome/geneticsPublished by: -
2Staff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Cardiac output, blood flow distribution and regional perfusion were determined in free-swimming rainbow trout acclimated to 6, 12 and 18°C, using the indicator dilution and microsphere methods. Cardiac output (ml min−1 kg−1) increased linearly with increasing temperature, while circulation time decreased. Blood flow distribution (% of cardiac output) to the spleen, liver, kidney, gall bladder and gastro-intestinal tract was significantly reduced at 18°C relative to 6°C-acclimated fish. White muscle received the largest fraction of cardiac output, and blood flow distribution to white muscle increased significantly with increasing acclimation temperature. Blood perfusion (ml h−1 g−1) of various organs and red muscle was not influenced by acclimation temperature, while white muscle perfusion increased with increasing temperature. These results demonstrate physiological adaptation of the cardiovascular system of rainbow trout to changes in acclimation temperature.Type of Medium: Electronic ResourceURL: -
3Schultz, I. R. ; Barron, M. G. ; Newman, M. C. ; Vick, A. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1999Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Blood flow (as percentage of cardiac output) in fasted channel catfish acclimated to 21°C was directed primarily to white muscle (72%) followed by head kidney (5·7%), red muscle (5·5%), trunk kidney (3·1%), liver (2·2%), swim bladder (1·4%) and skin (1·1%). The stomach, intestines, pyloric caeca, gonads, brain, abdominal fat and spleen contained 〈0·5% of blood flow. There was considerable interfish variation among blood flow distribution to visceral organs with substantial spatial heterogeneity of blood flow to white muscle. The spatial heterogeneity of flow to muscle prevented accurate estimation of total flow to this tissue based on the microsphere deposition of a few sub-samples. Instead, a novel approach, based on the whole animal counting of the eviscerated carcass was used to measure blood flow to white muscle. The scaling relationships for tissue mass in catfish (63–1873 g) followed the allometric equation (aWb) and tended to exhibit negative allometry, with organ weight decreasing in proportion to body weight. The b values for most tissues ranged between 0·83 and 1·0. The relative mass of the brain showed the greatest decline and with a b value of 0·32. The results, together with previous data on cardiac output, permitted calculation of organ blood flow rates in channel catfish. © 1999 The Fisheries Society of the British IslesType of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 0022-460XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsType of Medium: Electronic ResourceURL: -
5Choe, B. K. ; Lillehoj, H. S. ; Dong, M. K. ; Gleason, S. ; Barron, M. ; Rose, N. R.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1432-0800Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicineType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0040-6031Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
8Kerr, D. ; Stanley, J. C. ; Barron, M. ; Thomas, R. ; Leatherdale, B. A. ; Pickard, J.
Springer
Published 1993Staff ViewISSN: 1432-0428Keywords: Hypoglycaemia ; cerebral hemispheres ; cognitive function ; cerebral blood flowSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary A low blood glucose level is associated with impairment of higher cerebral function and an increase in cerebral blood flow. This study examined whether there are differences in the physiological responses to hypoglycaemia between the cerebral hemispheres. Eight healthy men participated in two hyperinsulinaemic glucose clamp studies: after 60 min at 4.5 mmol/l, blood glucose was either lowered to 2.0 mmol/l and “clamped” there for 60 min (hypoglycaemia) or continuously maintained at 4.5 mmol/l (euglycaemia). Cardiac output, middle cerebral artery velocity (transcranial Doppler) and cerebral blood flow (133-xenon inhalation) were measured during the studies. Neuropsychological tests were used to determine whether hypoglycaemia caused differential impairment of hemispheric cognitive function. Hypoglycaemia was associated with symmetrical impairment of cognitive function in both cerebral hemispheres and a rise in cardiac output (from 5.5 [0.2] to 8.7 [0.2] l · min−1 p〈0.0001, mean [standard error]), middle cerebral artery velocity (from 55 [2.6] to 64 [2.8] cm·s−1, p〈0.002), and global cerebral blood flow (from 56 [2.6] to 69 [2.9] ml·100 g−1·min−1, p〈0.005 compared to pre-insulin values). There were no differences in the blood flow response during hypoglycaemia between hemispheres and the increase in blood flow did not correlate with either the change in cardiac output or rise in plasma catecholamine levels. After 120 min of hyperinsulinaemic, euglycaemia, global cerebral blood flow rose significantly above baseline (from 58 [2.4] to 63 [2.2] ml·100 g−1·min−1, p〈0.05). In conclusion, using the techniques described, the physiological and cognitive responses of each cerebral hemisphere to hypoglycaemia were symmetrical. Hyperinsulinaemia, independent of blood glucose level, may be associated with an increase in cerebral blood flow.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1432-0800Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicineType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1432-0800Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringMedicineType of Medium: Electronic ResourceURL: -
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ISSN: 1573-9104Keywords: common bean ; drought effect ; proline metabolism ; tepary beanSource: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract There are several mechanisms used by plants for survival in adverse environments such as drought, high temperature and salinity. The objective of this study was to evaluate the drought tolerance of tepary bean as a function of biochemical processes linked to isozyme synthesis and changes in enzymatic activity related to proline metabolism. Mature seeds of common beans var. flor de mayo, Phaseolus vulgaris and tepary beans Phaseolus acutifolius were grown under two water conditions (irrigation and drought), and four levels of urea. Vertical electrophoresis and spectrophotometric techniques were used to evaluate protein patterns, glutamate dehydrogenase (GDH), proline oxidase (PO) and pyrroline-5-carboxylate reductase (P5C reductase) enzyme activities. These enzymes were studied because they are directly related to protein synthesis. Electrophoretic patterns showed more proteins in tepary beans than in common beans with limited irrigation. GDH showed only one isozyme, with a molecular weight between 240 to 270 kDa. A decrease in PO activity was observed in common beans under drought stress with a value of 237 μmol/min, in comparison to irrigation conditions of 580 μmol/min. GDH and P5C reductase enzymes have had higher activity in common beans than in tepary beans under water stress. There was a significant difference only in glutamate dehydrogenase enzyme with respect to urea level. The results suggest that drought tolerance of tepary beans is due to biochemical processes related to proline metabolic enzymes.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0360-6376Keywords: Physics ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: The ability of styrene-methyl methacrylate copolymers to stabilize silica dispersions has been investigated. Random, block, and graft copolymers covering the entire composition range have been employed in carbon tetrachloride, trichloroethylene, and benzene solutions. Equilibrium sediment volumes and dispersion turbidities provide adequate and concordant estimates of stabilization efficiency. Polystyrene is not adsorbed by precipitated silica from trichloroethylene or benzene and does not stabilize dispersions in these liquids; although adsorbed from carbon tetrachloride, there is no stabilization. Poly(methyl methacrylate) is an efficient dispersion stabilizer, and its performance is independent of molecular weight over a wide range. Random copolymers having styrene contents in excess of ca. 60% do not stabilize in trichloroethylene but do so in carbon tetrachloride, although well adsorbed in both cases. With this major exception, and that of a low-styrene graft copolymer in carbon tetrachloride, copolymers of all structures and compositions stabilize well, better than poly(methyl methacrylate) in the solvents examined. A substantial degree of surface coverage is necessary for optimum stabilization. Subsidiary solution adsorption and layer thickness measurements are also reported.Additional Material: 14 Ill.Type of Medium: Electronic ResourceURL: -
13Aguilar, R. ; Alvarez, Jo. ; González, J. ; Barrón, M. A.
Chichester : Wiley-Blackwell
Published 1996Staff ViewISSN: 0268-2575Keywords: fermentation processes ; uncertainties estimation ; robust stabilisation ; Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: Identification and control of continuous fermentation processes are dif-ficult tasks due to the complexity and high coupling of dynamic behaviour of this kind of system. In this work is implemented an on-line estimation technique of the main uncertainties of a fermentation processes (e.g. specific growth rate, biomass concentration and yield coefficient) based on a mass balance, to generate a linearising feedback control law that provides a robust stabilisation against uncertainties. By numerical simulations the performance of the closed-loop system and the controller design procedure is illustrated.Additional Material: 5 Ill.Type of Medium: Electronic Resource