Search Results - (Author, Cooperation:M. Baens)

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  1. 1
    S. Rosebeck ; L. Madden ; X. Jin ; S. Gu ; I. J. Apel ; A. Appert ; R. A. Hamoudi ; H. Noels ; X. Sagaert ; P. Van Loo ; M. Baens ; M. Q. Du ; P. C. Lucas ; L. M. McAllister-Lucas
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-01-29
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Apoptosis ; B-Lymphocytes/*metabolism ; Cell Adhesion ; Cell Line ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Humans ; I-kappa B Kinase/metabolism ; Lymphoma, B-Cell, Marginal Zone/genetics/*metabolism ; NF-kappa B/*metabolism ; NF-kappa B p52 Subunit/metabolism ; Oncogene Proteins, Fusion/chemistry/genetics/*metabolism ; Phosphorylation ; Protein Structure, Tertiary ; Protein-Serine-Threonine Kinases/genetics/*metabolism ; Proto-Oncogene Proteins/genetics/metabolism ; Signal Transduction ; Substrate Specificity
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/geno.1994.1136

    Articles: DFG German National Licenses
  3. 3
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/geno.1993.1161

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    0890-8508
    Keywords:
    Reverse dot-blot ; chemiluminescence ; cystic fibrosis ; multiplex polymerase chain reaction ; non-radioactive ; oligonucleotide probes
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0890-8508(92)90069-A

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/geno.1994.1267

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    0165-4608
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0165-4608(93)90115-3

    Articles: DFG German National Licenses
  7. 7
    Maes, B. ; Baens, M. ; Marynen, P. ; De Wolf-Peeters, Ch.
    Springer
    Published 2000
    Staff View
    ISSN:
    1569-8041
    Keywords:
    API2–MLT ; marginal zone cell lymphoma ; RT–PCR
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Background:Extranodal marginal zone cell lymphoma (MZCL) ofMALT-type share similar features with nodal and splenic MZCL regardingmorphology and immunophenotype. At the genetic level, recent cytogeneticstudies have shown that t(11;18) is a recurring abnormality in extranodalMALT-type MZCL but has hitherto never been reported in nodal or splenic MZCL.The aim of the present study was to determine the prevalence of t(11;18) ina large series of nodal, splenic and extranodal MALT-type MZCL, using asensitive real-time RT–PCR method. Materials and methods:Ninety-three MZCL cases were divided onclinical grounds into 61 extranodal MALT-type, 19 splenic and 12 nodal MZCL.One case that presented with a massive splenomegaly but for which alsogastro-intestinal localisations were found, was left unclassified. A real-timeRT–PCR method for the detection of the API2–MLT fusion resulting from t(11;18) was performed on RNA extracted from frozen tissuesections. Results:The API2–MLT fusion was detected in 12cases, which were all extranodal MALT-type lymphomas of the stomach, exceptfor one case. The remaining positive case was the unclassified case, for whichthe translocation was detected in the spleen and in hilar lymph node tissue. Conclusions:While similarities between MZCL from differentanatomic sites have lend us to propose that all MZCL have a common normalcounterpart, the almost exclusive detection of t(11;18) in gastric MALT-typelymphoma favours its recognition as a separate lymphoma entity. The absenceof the translocation in nodal and splenic MZCL challenges the idea of theselymphomas being secondary to MALT-type lymphomas of the gut. The unclassifiedcase illustrates the inadequate approaches available at present to identifyand define the various MZCL.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1008357314157

    Articles: DFG German National Licenses