Search Results - (Author, Cooperation:M. Asai)

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  1. 1
    Staff View
    Publication Date:
    2015-04-10
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2013-07-23
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adolescent ; Animals ; Body Mass Index ; Body Weight/*genetics ; Carrier Proteins/*genetics ; Child ; Child, Preschool ; Energy Metabolism/genetics ; Female ; Gene Deletion ; Humans ; Male ; Mice ; Mice, Knockout ; Obesity/*genetics/metabolism ; Receptor Activity-Modifying Proteins/genetics/*metabolism ; Receptor, Melanocortin, Type 4/genetics/*metabolism ; Young Adult
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2014-09-23
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Asai, M. ; Sato, F. ; Imamoto, H. ; Imanaka, K. ; Shimura, M.

    [S.l.] : American Institute of Physics (AIP)
    Published 1988
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Migration enhanced epitaxy, in which group III and group V elements are deposited onto the substrate alternately under ultrahigh vacuum, has been employed to reduce AlGaAs growth temperature. By optimizing growth conditions of AlGaAs, molecular-beam intensities, and substrate temperatures between 600 and 250 °C, an AlGaAs/GaAs single-quantum-well laser diode has been fabricated successfully at very low temperature of 350 °C for the first time. A broad area laser diode emitting at 780 nm shows the threshold current density of 2.5 kA/cm2 at room temperature under the pulsed operation.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.341211

    Articles: DFG German National Licenses
  5. 5
    Sato, F. ; Imamoto, H. ; Asai, M. ; Inoue, T. ; Imanaka, K. ; Shimura, M.

    [S.l.] : American Institute of Physics (AIP)
    Published 1988
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    A novel ridge waveguide laser diode has been developed in which the ridge is buried in a newly developed polyimide with a low thermal expansion coefficient close to that of AlGaAs which reduces the thermal stress to the junction and simplifies the wafer processing. A planar configuration, which is suitable for optoelectronic integration and an episide down mount for high-power operation, has been achieved by an etch-back process. Under cw operation, a low threshold current of 15 mA at 25 °C, a characteristic temperature T0 of 145 K, and maximum power output higher than 30 mW/facet have been obtained in a molecular-beam-epitaxial-grown graded-index separate confinement heterostructure single-quantum-well laser emitting at 780 nm.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.340042

    Articles: DFG German National Licenses
  6. 6
    Asai, M. ; Ueba, H. ; Tatsuyama, C.

    [S.l.] : American Institute of Physics (AIP)
    Published 1985
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The initial stage of Ge heteroepitaxy on a Si(100)-2×1 surface has been investigated by low-energy electron diffraction (LEED) and Auger-electron spectroscopy (AES). The growth mode of the Ge films was studied by measuring the decrease in the Si(LVV) AES line at 92 eV with an increase in the Ge overlayer thickness. The Ge films deposited at room temperature exhibit layer-by-layer growth up to at least six monolayers. When the substrate is heated up to 350 °C, the growth mode is characterized by the Stranski–Krastanov type; i.e., the first three monolayers of growth is followed by island formation. Although these characteristics of the growth mechanism are similar to the case of Ge on Si(111)-7×7 surfaces, annealing behavior of the Ge films suggests that the bond strength between Ge and Si is stronger on Si(100) than on Si(111) surfaces. In contrast to the case of Ge on Si(111) surfaces, where the original 7×7 superstructure of the Si surface is replaced by a new 5×5 pattern at about two-monolayer coverage of Ge, the original 2×1 LEED pattern is not strongly disturbed up to about 1–2 monolayers of Ge. In addition to the detailed study on the initial stage of heteroepitaxial growth, we observed that thick Ge films deposited onto Si(100) surfaces held at 350 and 470 °C display a sharp 2×1 LEED pattern and demonstrate a single-crystal growth of a Ge(100) face on the Si(100) surface. This is further supported by a measurement of the x-ray diffraction pattern of the Ge films.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.335886

    Articles: DFG German National Licenses
  7. 7
    ICHINOSE, M. ; ASAI, M. ; SAWADA, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The effects of β-endorphin (βEnd) on phagocytosis in peritoneal macrophages were examined by using flow cytometry (FCM). βEnd enhanced phagocytosis in a dose-dependent manner. Leucine—enkephalin (Leu-Enk), methionine—enkephalin (Met—Enk), α-endorphin (αEnd), γ-endorphin (γEnd), αEnd (18–31) and βEnd (28–31) had no such activity. βEnd (1–27) and βEnd (6–31) enhanced phagocytosis less effectively than βEnd did. Naloxone did not inhibit the enhancement of phagocytosis induced by βEnd. Unstimulated control phagocytosis was partially suppressed in Ca2+-free EGTA-containing solution and even in this solution βEnd enhanced phagocytosis. However, the enhancement was suppressed in the solution containing BAPTA-AM. The present study showed that βEnd enhanced extracellular Ca2+ ([Ca2+]o)-dependent and -independent phagocytosis and that the enhancement is largely dependent on intracellular Ca2+ ([Ca2+]i). These results support the contention that βEnd is one of the mediators that modulates the immune system.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-3083.1995.tb03661.x

    Articles: DFG German National Licenses
  8. 8
    Yamamori, E. ; Iwasaki, Y. ; Aoki, Y. ; Nomura, A. ; Tachikawa, K. ; Ariyoshi, Y. ; Mutsuga, N. ; Morishita, M. ; Yoshida, M. ; Asai, M. ; Oiso, Y. ; Saito, H.

    Oxford, UK : Blackwell Science, Ltd
    Published 2001
    Staff View
    ISSN:
    1365-2826
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Polyamines are a ubiquitous group of amines that play diverse biological roles. In the anterior pituitary, intracellular polyamine levels are reported to show diurnal changes, although the biological significance remains to be elucidated. In this study, we examined the effects of polyamines on the transcriptional activity of the rat pro-opiomelanocortin (POMC) gene using AtT20PL, a clone of the AtT20 cell line in which an approximately 0.7 kb of the rat POMC 5′ promoter-luciferase fusion gene was stably incorporated. The results showed that three representative polyamines (putrescine, spermidine and spermine) all stimulated POMC promoter activity in a time- and dose-related manner, spermine showing the most potent effect (maximum approximate three-fold increase). This effect was not observed under treatment with actinomycin D, suggesting the effect of polyamine at the transcriptional level. On the other hand, methylglyoxal bis (guanylhydrazone), an inhibitor of polyamine synthesis, showed the opposite effect, further supporting the positive role of intracellular polyamines. Taken together, our findings suggest that polyamines are involved in the regulation of POMC gene expression (especially in terms of diurnal changes) in corticotroph cells. The precise molecular mechanisms of polyamine effects await further research.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2826.2001.00691.x

    Articles: DFG German National Licenses
  9. 9
    Imada, A. ; Kitano, K. ; Kintaka, K. ; Muroi, M. ; Asai, M.

    [s.l.] : Nature Publishing Group
    Published 1981
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Screening for b-lactam antibiotics was carried out using a selective and sensitive method involving Pseudomonas aeruginosa PsCss (ref. 11) and Escherichia coli PG8 (lacking chromosomal b-lactamase and penicillin-binding protein (PBP) IB), which are hypersensitive to b-lactam antibiotics. Several ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/289590a0

    Articles: DFG German National Licenses
  10. 10
    Mizutani, F. ; Yabuki, S. ; Asai, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-2670
    Keywords:
    Amperometry ; Enzyme electrodes ; Lactate ; Malate ; Wines
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0003-2670(00)80214-7

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0003-2670
    Keywords:
    Amperometry ; Biosensors ; Enzymatic methods ; Enzyme electrodes ; Ferrocene ; Glucose ; Lysine polymers ; Polymeric mediators
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0003-2670(93)85006-6

    Articles: DFG German National Licenses
  12. 12
    Yabuki, S. ; Mizutani, F. ; Katsura, T. ; Asai, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0302-4598
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0302-4598(92)80037-H

    Articles: DFG German National Licenses
  13. 13
    Tanaka, M. ; Asai, M. ; Aoki, N. ; Tanimoto, M. ; Matsuno, R.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0922-338X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0922-338X(91)90258-I

    Articles: DFG German National Licenses
  14. 14
    Ataka, M. ; Asai, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-0248
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Geosciences
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0022-0248(88)90302-8

    Articles: DFG German National Licenses
  15. 15
    Kitazume, T. ; Asai, M. ; Lin, J.T. ; Yamazaki, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-1139
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0022-1139(00)81995-8

    Articles: DFG German National Licenses
  16. 16
    Yamazaki, T. ; Asai, M. ; Ohnogi, T. ; Lin, J.T. ; Kitazume, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-1139
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0022-1139(00)82001-1

    Articles: DFG German National Licenses
  17. 17
    Kitazume, T. ; Asai, M. ; Tsukamoto, T. ; Yamazaki, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-1139
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0022-1139(00)81174-4

    Articles: DFG German National Licenses
  18. 18
    Onda, M. ; Asai, M. ; Kohno, T. ; Kikuchi, Y. ; Yamaguchi, I.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-2860
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0022-2860(87)87051-5

    Articles: DFG German National Licenses
  19. 19
    Yabuki, S. ; Mizutani, F. ; Katsura, T. ; Asai, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-0728
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0022-0728(92)85111-F

    Articles: DFG German National Licenses
  20. 20
    Harada, S. ; Tsubotani, S. ; Shinagawa, S. ; Asai, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-4020
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0040-4020(01)97632-X

    Articles: DFG German National Licenses