Search Results - (Author, Cooperation:M. A. Ferreira)
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1Pedro Bule, Kate Cameron, Jose A. M. Prates, Luis M. A. Ferreira, Steven P. Smith, Harry J. Gilbert, Edward A. Bayer, Shabir Naȷmudin, Carlos M. G. A. Fontes, Victor D. Alves
The American Society for Biochemistry and Molecular Biology (ASBMB)
Published 2018Staff ViewPublication Date: 2018-03-17Publisher: The American Society for Biochemistry and Molecular Biology (ASBMB)Print ISSN: 0021-9258Electronic ISSN: 1083-351XTopics: BiologyChemistry and PharmacologyPublished by: -
2P. van der Harst ; W. Zhang ; I. Mateo Leach ; A. Rendon ; N. Verweij ; J. Sehmi ; D. S. Paul ; U. Elling ; H. Allayee ; X. Li ; A. Radhakrishnan ; S. T. Tan ; K. Voss ; C. X. Weichenberger ; C. A. Albers ; A. Al-Hussani ; F. W. Asselbergs ; M. Ciullo ; F. Danjou ; C. Dina ; T. Esko ; D. M. Evans ; L. Franke ; M. Gogele ; J. Hartiala ; M. Hersch ; H. Holm ; J. J. Hottenga ; S. Kanoni ; M. E. Kleber ; V. Lagou ; C. Langenberg ; L. M. Lopez ; L. P. Lyytikainen ; O. Melander ; F. Murgia ; I. M. Nolte ; P. F. O'Reilly ; S. Padmanabhan ; A. Parsa ; N. Pirastu ; E. Porcu ; L. Portas ; I. Prokopenko ; J. S. Ried ; S. Y. Shin ; C. S. Tang ; A. Teumer ; M. Traglia ; S. Ulivi ; H. J. Westra ; J. Yang ; J. H. Zhao ; F. Anni ; A. Abdellaoui ; A. Attwood ; B. Balkau ; S. Bandinelli ; F. Bastardot ; B. Benyamin ; B. O. Boehm ; W. O. Cookson ; D. Das ; P. I. de Bakker ; R. A. de Boer ; E. J. de Geus ; M. H. de Moor ; M. Dimitriou ; F. S. Domingues ; A. Doring ; G. Engstrom ; G. I. Eyjolfsson ; L. Ferrucci ; K. Fischer ; R. Galanello ; S. F. Garner ; B. Genser ; Q. D. Gibson ; G. Girotto ; D. F. Gudbjartsson ; S. E. Harris ; A. L. Hartikainen ; C. E. Hastie ; B. Hedblad ; T. Illig ; J. Jolley ; M. Kahonen ; I. P. Kema ; J. P. Kemp ; L. Liang ; H. Lloyd-Jones ; R. J. Loos ; S. Meacham ; S. E. Medland ; C. Meisinger ; Y. Memari ; E. Mihailov ; K. Miller ; M. F. Moffatt ; M. Nauck ; M. Novatchkova ; T. Nutile ; I. Olafsson ; P. T. Onundarson ; D. Parracciani ; B. W. Penninx ; L. Perseu ; A. Piga ; G. Pistis ; A. Pouta ; U. Puc ; O. Raitakari ; S. M. Ring ; A. Robino ; D. Ruggiero ; A. Ruokonen ; A. Saint-Pierre ; C. Sala ; A. Salumets ; J. Sambrook ; H. Schepers ; C. O. Schmidt ; H. H. Sillje ; R. Sladek ; J. H. Smit ; J. M. Starr ; J. Stephens ; P. Sulem ; T. Tanaka ; U. Thorsteinsdottir ; V. Tragante ; W. H. van Gilst ; L. J. van Pelt ; D. J. van Veldhuisen ; U. Volker ; J. B. Whitfield ; G. Willemsen ; B. R. Winkelmann ; G. Wirnsberger ; A. Algra ; F. Cucca ; A. P. d'Adamo ; J. Danesh ; I. J. Deary ; A. F. Dominiczak ; P. Elliott ; P. Fortina ; P. Froguel ; P. Gasparini ; A. Greinacher ; S. L. Hazen ; M. R. Jarvelin ; K. T. Khaw ; T. Lehtimaki ; W. Maerz ; N. G. Martin ; A. Metspalu ; B. D. Mitchell ; G. W. Montgomery ; C. Moore ; G. Navis ; M. Pirastu ; P. P. Pramstaller ; R. Ramirez-Solis ; E. Schadt ; J. Scott ; A. R. Shuldiner ; G. D. Smith ; J. G. Smith ; H. Snieder ; R. Sorice ; T. D. Spector ; K. Stefansson ; M. Stumvoll ; W. H. Tang ; D. Toniolo ; A. Tonjes ; P. M. Visscher ; P. Vollenweider ; N. J. Wareham ; B. H. Wolffenbuttel ; D. I. Boomsma ; J. S. Beckmann ; G. V. Dedoussis ; P. Deloukas ; M. A. Ferreira ; S. Sanna ; M. Uda ; A. A. Hicks ; J. M. Penninger ; C. Gieger ; J. S. Kooner ; W. H. Ouwehand ; N. Soranzo ; J. C. Chambers
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-12-12Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Cycle/genetics ; Cytokines/metabolism ; Drosophila melanogaster/genetics ; Erythrocytes/cytology/*metabolism ; Female ; Gene Expression Regulation/genetics ; *Genetic Loci ; *Genome-Wide Association Study ; Hematopoiesis/genetics ; Hemoglobins/genetics ; Humans ; Male ; Mice ; Organ Specificity ; *Phenotype ; Polymorphism, Single Nucleotide/genetics ; RNA Interference ; Signal Transduction/geneticsPublished by: -
3C. Gieger ; A. Radhakrishnan ; A. Cvejic ; W. Tang ; E. Porcu ; G. Pistis ; J. Serbanovic-Canic ; U. Elling ; A. H. Goodall ; Y. Labrune ; L. M. Lopez ; R. Magi ; S. Meacham ; Y. Okada ; N. Pirastu ; R. Sorice ; A. Teumer ; K. Voss ; W. Zhang ; R. Ramirez-Solis ; J. C. Bis ; D. Ellinghaus ; M. Gogele ; J. J. Hottenga ; C. Langenberg ; P. Kovacs ; P. F. O'Reilly ; S. Y. Shin ; T. Esko ; J. Hartiala ; S. Kanoni ; F. Murgia ; A. Parsa ; J. Stephens ; P. van der Harst ; C. Ellen van der Schoot ; H. Allayee ; A. Attwood ; B. Balkau ; F. Bastardot ; S. Basu ; S. E. Baumeister ; G. Biino ; L. Bomba ; A. Bonnefond ; F. Cambien ; J. C. Chambers ; F. Cucca ; P. D'Adamo ; G. Davies ; R. A. de Boer ; E. J. de Geus ; A. Doring ; P. Elliott ; J. Erdmann ; D. M. Evans ; M. Falchi ; W. Feng ; A. R. Folsom ; I. H. Frazer ; Q. D. Gibson ; N. L. Glazer ; C. Hammond ; A. L. Hartikainen ; S. R. Heckbert ; C. Hengstenberg ; M. Hersch ; T. Illig ; R. J. Loos ; J. Jolley ; K. T. Khaw ; B. Kuhnel ; M. C. Kyrtsonis ; V. Lagou ; H. Lloyd-Jones ; T. Lumley ; M. Mangino ; A. Maschio ; I. Mateo Leach ; B. McKnight ; Y. Memari ; B. D. Mitchell ; G. W. Montgomery ; Y. Nakamura ; M. Nauck ; G. Navis ; U. Nothlings ; I. M. Nolte ; D. J. Porteous ; A. Pouta ; P. P. Pramstaller ; J. Pullat ; S. M. Ring ; J. I. Rotter ; D. Ruggiero ; A. Ruokonen ; C. Sala ; N. J. Samani ; J. Sambrook ; D. Schlessinger ; S. Schreiber ; H. Schunkert ; J. Scott ; N. L. Smith ; H. Snieder ; J. M. Starr ; M. Stumvoll ; A. Takahashi ; W. H. Tang ; K. Taylor ; A. Tenesa ; S. Lay Thein ; A. Tonjes ; M. Uda ; S. Ulivi ; D. J. van Veldhuisen ; P. M. Visscher ; U. Volker ; H. E. Wichmann ; K. L. Wiggins ; G. Willemsen ; T. P. Yang ; J. Hua Zhao ; P. Zitting ; J. R. Bradley ; G. V. Dedoussis ; P. Gasparini ; S. L. Hazen ; A. Metspalu ; M. Pirastu ; A. R. Shuldiner ; L. Joost van Pelt ; J. J. Zwaginga ; D. I. Boomsma ; I. J. Deary ; A. Franke ; P. Froguel ; S. K. Ganesh ; M. R. Jarvelin ; N. G. Martin ; C. Meisinger ; B. M. Psaty ; T. D. Spector ; N. J. Wareham ; J. W. Akkerman ; M. Ciullo ; P. Deloukas ; A. Greinacher ; S. Jupe ; N. Kamatani ; J. Khadake ; J. S. Kooner ; J. Penninger ; I. Prokopenko ; D. Stemple ; D. Toniolo ; L. Wernisch ; S. Sanna ; A. A. Hicks ; A. Rendon ; M. A. Ferreira ; W. H. Ouwehand ; N. Soranzo
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-12-06Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Blood Platelets/*cytology/metabolism ; Cell Size ; Drosophila Proteins/genetics ; Drosophila melanogaster/genetics ; Europe ; Gene Expression Profiling ; Gene Silencing ; Genome, Human/genetics ; Genome-Wide Association Study ; Hematopoiesis/*genetics ; Humans ; Megakaryocytes/*cytology/metabolism ; Platelet Count ; Protein Interaction Maps ; Transcription, Genetic/genetics ; Zebrafish/genetics ; Zebrafish Proteins/geneticsPublished by: -
4M. K. Yun ; Y. Wu ; Z. Li ; Y. Zhao ; M. B. Waddell ; A. M. Ferreira ; R. E. Lee ; D. Bashford ; S. W. White
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-03-03Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: 4-Aminobenzoic Acid/chemistry/metabolism ; Amino Acid Sequence ; Anti-Bacterial Agents/chemistry/metabolism/*pharmacology ; Bacillus anthracis/drug effects/enzymology ; Biocatalysis ; Catalytic Domain ; Crystallization ; Crystallography, X-Ray ; Dihydropteroate Synthase/*chemistry/genetics/*metabolism ; Diphosphates/chemistry/metabolism ; *Drug Resistance, Bacterial ; Magnesium/chemistry ; Models, Chemical ; Models, Molecular ; Molecular Sequence Data ; Mutagenesis ; Parabens/chemistry/metabolism ; Protein Conformation ; Sulfamethoxazole/chemistry/metabolism/*pharmacology ; Sulfathiazoles/chemistry/metabolism/*pharmacology ; Yersinia pestis/drug effects/enzymologyPublished by: -
5Arruda, G. M. T. ; Miller, R. N. G. ; Ferreira, M. A. S. V. ; Café-Filho, A. C.
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Brazilian Fusarium isolates causing soybean sudden death syndrome (SDS) were characterized by comparing them with other Fusarium isolates associated with soybean root rot, as well as F. solani f.sp. glycines isolates associated with the disease in the USA, using molecular (mitochondrial and nuclear rDNA), morphological, cultural and pathogenic characteristics. On the basis of pathogenicity data, and restriction fragment length polymorphism and sequence analysis of the rDNA internal transcribed spacer (ITS) regions, isolates formed a group distinct from nonSDS F. solani isolates, as well as other Fusarium species. ITS sequence analysis also revealed that Brazilian isolates were distinct from the majority of SDS pathogens from the USA (Fusarium virguliforme) and conformed to Fusarium tucumaniae.Type of Medium: Electronic ResourceURL: -
6De Arruda, M. C. C. ; Miller, R. N. G. ; Ferreira, M. A. S. V. ; Felipe, M. S. S.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Fifty isolates of Crinipellis perniciosa originating from Theobroma cacao, Heteropterys acutifolia and Solanum lycocarpum, from six states within Brazil, were characterized through ERIC-PCR, representing the first application of this method for molecular characterization within C. perniciosa. Phenetic analysis of banding patterns revealed a separation of isolates on the basis of host of origin, with T. cacao-derived isolates showing only a 0·2 similarity level to a cluster comprising the isolates from H. acutifolia and S. lycocarpum. Considerable intraspecific variability was observed within C. perniciosa isolates from T. cacao, with distinct groups observed correlating with geographical origin. Given that a number of isolates from T. cacao from the Amazon region grouped with isolates from Bahia state, this work discusses the possibility that current C. perniciosa populations pathogenic on T. cacao in Bahia originated from the Amazon region, rather than from alternative host plants.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1432-1998Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract A case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with prune belly syndrome (PBS). After a review of the literature, many common characteristic of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process.Type of Medium: Electronic ResourceURL: -
8Esteves da Silva, J. C. G. ; Machado, A. A. S. C. ; Ferreira, M. A. ; Rey, Francisco
Springer
Published 1998Staff ViewISSN: 1432-1130Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyNotes: Abstract The acid-base properties of four leaf litter extracts, LLE (eucalyptus, fern, oak and chestnut coverture), were characterized by synchronous fluorescence (SyF) spectroscopy and compared with those of two fulvic acids (FA) extracted from two different horizons (0–5 and 5–15 cm) of an oak forest soil. The characterization was based on the variation with the pH of the properties of the fluorescent structures present in the samples, which function as probes and provide a macroscopic image of their acid-base properties. These sets of SyF spectra collected as a function of the pH show fingerprinting potential. They were treated by a self-modeling curve resolution procedure, evolving factor analysis with a gradient concentration window (EFA-GCW), to reduce the raw spectral data to the number of components, their spectra, and SyF intensity profiles (pH distribution diagrams). Four acid-base systems were detected for all samples of LLE and FA with pKas ranging from 2.5 to 10.0 (pKas about 3, 5, 7 and 9, except for the fern LLE sample which showed pKas about 5, 7, 9 and 10). A similarity analysis of the spectra of the components, performed by cluster analysis, showed that the most acidic fluorescent structures of the LLE are not similar to those of the soil FA, but the less acidic are.Type of Medium: Electronic ResourceURL: -
9Carvalho, F. D. ; Remião, F. ; Valet, P. ; Timbrell, J. A. ; Bastos, M. L. ; Ferreira, M. A.
New York, NY : Wiley-Blackwell
Published 1994Staff ViewISSN: 0269-3879Keywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: MedicineNotes: An HPLC method using a glassy carbon working detector for measuring cysteine and reduced glutathione (GSH) in biological samples was developed. Oxidized glutathione (GSSG) was also measured after reduction with glutathione reductase. This study was conducted in human plasma. Cysteine and GSH standard curves were linear in the physiological range, presenting detection limits of 22.0 pmol and 6.0 pmol respectively. Plasmatic results found were 43.92 ± 4.15, 4.50 ± 0.65, and 0.19 ± 0.12 mM (means ± SE), for cysteine, GSH and GSSG, respectively. Peak specificity for cysteine and reduced glutathione was certified by their disappearance after treatment with N-ethylmaleimide.Additional Material: 2 Ill.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1052-9306Keywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: A mass spectrometric study of six new α-methylene-γ-lactone carbohydrate derivatives has been carried out in order to correlate the occurrence of metastable transitions with the stereochemistry of the compounds. Results indicate that the decomposition of some metastable fragment ions usually releases higher amounts of kinetic energy when the chiral centre of the lactone ring has the (S) configuration. However, the kinetic energy released on the decomposition of metastable molecular ions seems to follow different trends as regards the configuration of the chiral centre of the lactone moiety, when one or two isopropylidene rings are present in the molecule. This study is being extended to some related compounds in order to confirm whether the kinetic energy release is preferentially affected in a particular way by the chirality.Additional Material: 1 Ill.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0030-493XKeywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: A mass spectrometric study of eight new carbohydrate derivatives has been carried out to determine the influence of structure on the fragmentation mechanisms of stereoisomers. Results indicate that the relative intensities of peaks due to fragment ions of each pair of isomers are sometimes very different, especially those observed in the collision-induced decomposition mass spectra of [MH]+ ions. Metastable decompositions related to identical fragmentation processes of two isomers release different amounts of kinetic energy, however. It is usually observed that the kinetic energy released is larger for the S-configuration than for the R-configuration of the two epimers of a particular species.Additional Material: 6 Ill.Type of Medium: Electronic ResourceURL: -
12Ferreira, M. A. Almoster ; Cabral, B. J. Costa ; Oliveira, M. C. ; Baer, T.
Chichester : Wiley-Blackwell
Published 1993Staff ViewISSN: 0030-493XKeywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: The breakdown diagrams and photoionization efficiency curves of isomeric chlorobutane ions were obtained by energy-selected molecular ions with the photoelectron-photoion coincidence (PEPICO) technique. The loss of HCl from 1- and 2-chlorobutane molecular ions was found to be fast, and accurate dissociation onsets were determined from the crossover energy in the breakdown diagrams and appropriately corrected for the precursor thermal energy. In spit of the low activation energy, the isochlorobutane molecular ion was found to dissociate slowly near the dissociation limit, the time-of-flight distribution having been analyzed in terms of two exponential decay rates. The dissociation reaction involved a large kinetic energy release that pointed to a 1,2-elimination leading to a stable C4H8+· ion. AB initio calculations indicated that the reaction path involved an H-atom transfer through a barrier, which is a favorable case for a tunneling model to explain the slow decomposition rate. The kinetic energy release of chlorine radical loss from tert-chlorobutane was determined as a function of the ion internal energy. At low energies the kinetic energy release was nearly statistical but the dissociation from the excited electronic states resulted in a large and non-statistical kinetic energy release.Additional Material: 9 Ill.Type of Medium: Electronic ResourceURL: