Search Results - (Author, Cooperation:Lecrenier)

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  1. 1
    Staff View
    ISSN:
    0020-708X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Energy, Environment Protection, Nuclear Power Engineering
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0020-708X(57)90223-5

    Articles: DFG German National Licenses
  2. 2
    Koninck, L. L. ; Lecrenier, Ad.
    Springer
    Published 1889
    Staff View
    ISSN:
    1618-2650
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01375886

    Articles: DFG German National Licenses
  3. 3
    Staff View
    ISSN:
    1618-2650
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01369900

    Articles: DFG German National Licenses
  4. 4
    Lecrenier, Nicolas ; Foury, Françoise
    Springer
    Published 1995
    Staff View
    ISSN:
    1617-4623
    Keywords:
    Polymerase ; Ribonucleotide reductase ; Mitochondrial DNA ; Saccharomyces cerevisiae ; Cell cycle
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract A multicopy suppressor gene which rescues the temperature-sensitive growth defect of Saccharomyces cerevisiae mutants in the mitochondrial DNA (mtDNA) polymerase-encoding MIP1 gene has been isolated and identified as the RNR1 gene. This gene, whose transcript is cell cycle-regulated and mainly expressed at the G1 to S phase transition, encodes the large subunit of ribonucleotide reductase. This enzyme catalyses a limiting step in the production of deoxynucleotides needed for DNA synthesis. The presence of a high copy number of the RNR1 gene also decreases the accumulation of rho− mutants observed in diploids that harbour a single copy of the MIP1 gene. In cell cycle-synchronised cells, the presence of a high copy number of RNR1 does not modify its cell cycle transcription regulation and increases its transcript level by a factor of 10 throughout the cell cycle. Our results show that an increased supply of dNTPs in mitochondria can stimulate the mtDNA polymerase activity and indicate that the dNTP concentration may be rate limiting for the replication of mtDNA.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00290229

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1618-2650
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01455607

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    1618-2650
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01334067

    Articles: DFG German National Licenses
  7. 7
    de Koninck, L. L. ; Lecrenier, Ad.

    Weinheim : Wiley-Blackwell
    Published 1888
    Staff View
    ISSN:
    0044-8249
    Keywords:
    Chemistry ; General Chemistry
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Chemistry and Pharmacology
    Additional Material:
    1 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1002/ange.18880011204

    Articles: DFG German National Licenses