Search Results - (Author, Cooperation:L. Wolfe)

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  1. 1
    Stapert, L., Wolfe, C., Shinabarger, D., Marra, A., Pillar, C.
    The American Society for Microbiology (ASM)
    Published 2018
    Staff View
    Publication Date:
    2018-03-28
    Publisher:
    The American Society for Microbiology (ASM)
    Print ISSN:
    0066-4804
    Electronic ISSN:
    1098-6596
    Topics:
    Biology
    Medicine
    Published by:
    http://www.asm.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    T. M. Williams ; L. Wolfe ; T. Davis ; T. Kendall ; B. Richter ; Y. Wang ; C. Bryce ; G. H. Elkaim ; C. C. Wilmers
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-10-04
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; *Carnivora ; *Energy Metabolism ; *Predatory Behavior ; Puma/*metabolism/*psychology ; Running
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2014-08-01
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    5' Untranslated Regions/*genetics ; Animals ; Antineoplastic Agents, Phytogenic/pharmacology/therapeutic use ; Base Sequence ; Cell Line, Tumor ; Epigenesis, Genetic ; Eukaryotic Initiation Factor-4A/*metabolism ; Female ; *G-Quadruplexes ; Humans ; Mice ; Mice, Inbred C57BL ; Nucleotide Motifs ; Oncogene Proteins/*biosynthesis/*genetics ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug ; therapy/genetics/*metabolism ; *Protein Biosynthesis/drug effects ; Ribosomes/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic/drug effects/genetics ; Triterpenes/pharmacology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2014-08-21
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Bone and Bones/microbiology ; Europe/ethnology ; Genome, Bacterial/*genetics ; Genomics ; History, Ancient ; Human Migration/history ; Humans ; Mycobacterium tuberculosis/*genetics ; Peru ; Phylogeny ; Pinnipedia/*microbiology ; Tuberculosis/*history/*microbiology/transmission ; Zoonoses/*history/*microbiology/transmission
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    T. K. Warren ; R. Jordan ; M. K. Lo ; A. S. Ray ; R. L. Mackman ; V. Soloveva ; D. Siegel ; M. Perron ; R. Bannister ; H. C. Hui ; N. Larson ; R. Strickley ; J. Wells ; K. S. Stuthman ; S. A. Van Tongeren ; N. L. Garza ; G. Donnelly ; A. C. Shurtleff ; C. J. Retterer ; D. Gharaibeh ; R. Zamani ; T. Kenny ; B. P. Eaton ; E. Grimes ; L. S. Welch ; L. Gomba ; C. L. Wilhelmsen ; D. K. Nichols ; J. E. Nuss ; E. R. Nagle ; J. R. Kugelman ; G. Palacios ; E. Doerffler ; S. Neville ; E. Carra ; M. O. Clarke ; L. Zhang ; W. Lew ; B. Ross ; Q. Wang ; K. Chun ; L. Wolfe ; D. Babusis ; Y. Park ; K. M. Stray ; I. Trancheva ; J. Y. Feng ; O. Barauskas ; Y. Xu ; P. Wong ; M. R. Braun ; M. Flint ; L. K. McMullan ; S. S. Chen ; R. Fearns ; S. Swaminathan ; D. L. Mayers ; C. F. Spiropoulou ; W. A. Lee ; S. T. Nichol ; T. Cihlar ; S. Bavari
    Nature Publishing Group (NPG)
    Published 2016
    Staff View
    Publication Date:
    2016-03-05
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alanine/*analogs & derivatives/pharmacokinetics/pharmacology/therapeutic use ; Amino Acid Sequence ; Animals ; Antiviral Agents/pharmacokinetics/pharmacology/*therapeutic use ; Cell Line, Tumor ; Ebolavirus/drug effects ; Female ; HeLa Cells ; Hemorrhagic Fever, Ebola/*drug therapy/prevention & control ; Humans ; Macaca mulatta/*virology ; Male ; Molecular Sequence Data ; Organ Specificity ; Prodrugs/pharmacokinetics/pharmacology/therapeutic use ; Ribonucleotides/pharmacokinetics/pharmacology/*therapeutic use
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Gilbert, L. Wolfe

    New York : Periodicals Archive Online (PAO)
    Published 1954
    Staff View
    ISSN:
    0027-4364
    Topics:
    Musicology
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:1166-1954-011-00-000010

    Articles: DFG German National Licenses
  7. 7
    Wolfe, L. S. ; Rostworowski, K. ; Pellerin, L. ; Sherwin, A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1989
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: In homogenates of rat cerebral neocortex prostaglandin D2 (PGD2) was found to be quantitatively the main PG biosynthesized by a cytosolic PGD synthetase from en-dogenously released arachidonic acid. Amounts of 628 ng/g wet weight were found after 30-min incubation periods compared with basal levels of 2.3 ng/g wet weight. In human cerebral cortex, whether obtained at biopsy or postmortem, only small amounts of PGD2 (4.5–11.7 ng/g wet weight/30 min) were formed. Furthermore, PGD2, added to homogenates of human biopsy temporal cortex, was converted efficiently into 9α,11β-PGF2 by a NADPH-dependent 11-ke-toreductase as has been reported in other human tissues (liver and lung). PGF2α was determined directly as the fl-butylbo-ronate derivative. It became clear that 9α,11β-PGF2 was formed in considerably greater amounts than PGF2α and that other metabolites are also formed. These results can account for the low amounts of PGD2 found in incubations of human brain tissue. The rat brain does not contain 11-ketoreductase activity. The present results indicate that the 9α, 11β-PGF2 must be considered along with other eicosanoids in pathophysiological situations in brain.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1989.tb07295.x

    Articles: DFG German National Licenses
  8. 8
    Heller, I. H. ; Wolfe, L. S. ; Hesse, S.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1962
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1962.tb09472.x

    Articles: DFG German National Licenses
  9. 9
    Wolfe, L. S. ; Klatzo, Igor ; Miquel, Jaime ; Tobias, Cornelius ; Haymaker, Webb

    Oxford, UK : Blackwell Publishing Ltd
    Published 1962
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1962.tb11862.x

    Articles: DFG German National Licenses
  10. 10
    Breckenridge, W. Carl ; Wolfe, L. S. ; Ng Ying Kin, N. M. K.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1973
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract— Long-chain polyisoprenols were isolated from brain in yields of 10-15 mg/kg tissue wet weight. On thin-layer chromatography, migrations were identical for brain polyisoprenols and pig liver dolichol which had been isolated as reference material. The IR, 1H NMR and 13C (FT) NMR spectra of calf brain polyisoprenols were consistent with a molecular structure which had a saturated isoprenol unit followed by approximately 19 unsaturated isoprene units. About 3-4 isoprene units possessed trans double bonds. Using reversed phase thin-layer chromatography and pig liver dolichol as a reference, it was estimated that calf brain polyisoprenols had major structures of C95, C100 and C105 while rat brain polyisoprenols contained C90 and C95 as the major components. All data indicated that the brain polyisoprenols were very similar, chemically, to pig liver dolichols except for minor differences in molecular weight.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1973.tb07584.x

    Articles: DFG German National Licenses
  11. 11
    Spence, M. W. ; Wolfe, L. S.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1967
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1967.tb09559.x

    Articles: DFG German National Licenses
  12. 12
    Wolfe, L. S. ; Breckenridge, W. C. ; Skelton, P. P. C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1974
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract— Mannose was transferred from GDP-[14C]mannose by homogenates of embryonic chick and adult rat brain to mannolipids with properties identical to manriosyl-phosphoryl-dihydropolyisoprenols. Embryonic chick brain formed six-fold larger quantities of mannolipid than adult rat brain. The reaction was stimulated by Mn2+ ions and Triton X-100 but inhibited by EDTA. Phosphoenolpyruvic acid had no effect on the reaction. A crude mitochondrial fraction was two to three times more active than the microsomal fraction. All radioactivity in the mannolipid could be displaced by the addition of non-radioactive GDP-mannose. The endogenous lipid acceptor in brain was readily labelled in vivo by injection of [3H]mevalonate into the amniotic sac of 7-day-old embryos. The mannolipid formed had the properties of an acidic phospholipid on column and TLC, was stable to dilute alkali but readily cleaved by dilute acid. Synthesis was markedly stimulated by the addition of pig liver or calf brain dolichol phosphate in the presence of Triton X-100 and Mn2+. The mannolipid so formed displayed chemical characteristics identical to the endogenous lipid acceptor. Incubation of the purified radioactive mannolipid with the ‘post-nuclear’ fraction from 14-day-old embryonic chick brain in the presence of EDTA and Triton X-100 resulted in the transfer of 40-50 per cent of the radioactive mannose to protein and 40-45 per cent to water soluble compounds. The efficiency of transfer of radioactivity from endogenously formed mannolipid with or without the addition of dolichol phosphate was similar to exogenously added highly purified mannolipid. These results are compatible with the hypothesis that synthesis of the mannose core of brain glycoproteins involves the synthesis first of mannosyl-phosphoryl-dolichols followed by transfer of the mannose to glycoprotein.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1974.tb06932.x

    Articles: DFG German National Licenses
  13. 13
    WOLFE, L. S. ; PELLERIN, L.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1989
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1749-6632.1989.tb22599.x

    Articles: DFG German National Licenses
  14. 14
    Kin, N. M. K. Ng Ying ; Palo, J. ; Haltia, M. ; Wolfe, L. S.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1983
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: Dolichols as unesterified alcohols were identified as significant components of lipid extracts from storage cytosomes isolated post-mortem from the brains of patients with the infantile, late infantile, and juvenile types of neuronal ceroid-lipofuscinosis (NCL). Very small amounts of dolichols were present in the corresponding subcellular fractions of non-NCL brains. The nuclear fraction from NCL cerebral cortex contained the highest dolichol content expressed per milligram protein or lipid, whereas the crude mitochondrial fraction was the richest in normal brain. Highly significant elevations of dolichol levels were found in human cerebral cortex of patients with NCL and Alzheimer's disease compared with age-matched controls, but the levels were normal in Pick's disease. In human non-NCL cerebral cortex, dolichols increased from 16 μg/g at age 5 to over 200 at age 81. Rat cerebral cortex showed a similar progressive increase in dolichol content with age. The high dolichol values in NCL, Alzheimer's disease, and senescence appears to be related to the increase of lipofuscin in brain. This is the first time a uniform biochemical abnormality has been found in all childhood forms of NCL, but the enzyme defect is still unidentified. It may lie on pathways where dolichols and retinyl compounds are recycled in Golgi membranes and derived organelles during the biosynthesis of glycoproteins.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1983.tb13592.x

    Articles: DFG German National Licenses
  15. 15
    NEWTON, J. C. ; WOLFE, L. G. ; GRIZZLE, J. M. ; PLUMB, J. A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1989
    Staff View
    ISSN:
    1365-2761
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    Abstract. Fingerling channel catfish, Ictalurus punctatus (Rafinesque), were exposed experimentally to Edwardsiella ictaluri by immersion for 1 h in water containing 5 × 108 colony-forming units (CFU) of the bacterium per ml. Ninety per cent of the fish developed lesions typical of enteric septicaemia of catfish (ESC), 93% of affected fish developed the acute form of ESC and 7% developed chronic ESC. Acute disease was characterized grossly by cutaneous haemorrhage and ulceration, and microscopically by enteritis, olfactory sacculitis, hepatitis and dermatitis. The earliest lesions of acute ESC, i.e. enteritis and olfactory sacculitis, were observed microscopically at 2 days post-exposure (PE); gross lesions, primarily mild subcutaneous haemorrhage at the base of fins, were first apparent at 4 days PE. Chronic ESC, seen most commonly 3–4 weeks PE, was characterized by dorsocranial swelling and ulceration, granulomatous olfactory neuritis/perineuritis, and meningoencephalitis involving the olfactory bulbs, olfactory tracts and olfactory lobes of the brain. Gross and microscopic lesions in the acute and chronic forms of experimental ESC were similar to the lesions reported in naturally occurring ESC. Definitive pathogenesis of acute and chronic ESC remains to be determined.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2761.1989.tb00322.x

    Articles: DFG German National Licenses
  16. 16
    HOLMES, A. W. ; DEINHARDT, F. ; WOLFE, L. ; FROESNER, G. ; PATERSON, D. ; CASTO, B. ; CONRAD, M. E.

    [s.l.] : Nature Publishing Group
    Published 1973
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Table 1 Inoculation of Coded Human Specimens into Marmosets No. of experi-ments Species of marmoset Type of inoculum Number of specimens Marmosets hepatitis/ inoculated 5 S. fuscicollis, N 8 0/52 S. nigricollis H 11 47/56 1 S. (Oedipomidas) N 2 0/7 oedipus ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/243419a0

    Articles: DFG German National Licenses
  17. 17
    ALMEIDA, J. D. ; DEINHARDT, F. ; HOLMES, A. W. ; PETERSON, D. A. ; WOLFE, L. ; ZUCKERMAN, A. J.

    [s.l.] : Nature Publishing Group
    Published 1976
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Fig. 1 Aggregate of small spherical particles 20?22 nm in diameter found in the highest infectivity serum of marmoset infected with the GB agent. In this particular specimen the infectious marmoset serum had been reacted with recovery serum, 275,000. Serum for examination was chosen from the ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/261608a0

    Articles: DFG German National Licenses
  18. 18
    Wolfe, L. ; Corbin, J.D.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0955-0674
    Keywords:
    ADP-adenosine diphosphate ; ANF-atrial natriuretic factor ; ATP-adenosine triphosphate ; CF-cystic fibrosis ; EDRF-endothelial -derived relaxing factor ; cAMP-cyclic adenosine monophosphate ; cGMP-cyclic guanosine monophosphate
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0955-0674(89)90090-2

    Articles: DFG German National Licenses
  19. 19
    Kevy, S.V. ; Fosburg, M. ; Wolfe, L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-9120
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0009-9120(83)80024-1

    Articles: DFG German National Licenses
  20. 20
    Kevy, S.V. ; Fosburg, M. ; Wolfe, L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-9120
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0009-9120(83)80024-1

    Articles: DFG German National Licenses