Search Results - (Author, Cooperation:L. W. Chang)

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  1. 1
    M. J. Ellis ; L. Ding ; D. Shen ; J. Luo ; V. J. Suman ; J. W. Wallis ; B. A. Van Tine ; J. Hoog ; R. J. Goiffon ; T. C. Goldstein ; S. Ng ; L. Lin ; R. Crowder ; J. Snider ; K. Ballman ; J. Weber ; K. Chen ; D. C. Koboldt ; C. Kandoth ; W. S. Schierding ; J. F. McMichael ; C. A. Miller ; C. Lu ; C. C. Harris ; M. D. McLellan ; M. C. Wendl ; K. DeSchryver ; D. C. Allred ; L. Esserman ; G. Unzeitig ; J. Margenthaler ; G. V. Babiera ; P. K. Marcom ; J. M. Guenther ; M. Leitch ; K. Hunt ; J. Olson ; Y. Tao ; C. A. Maher ; L. L. Fulton ; R. S. Fulton ; M. Harrison ; B. Oberkfell ; F. Du ; R. Demeter ; T. L. Vickery ; A. Elhammali ; H. Piwnica-Worms ; S. McDonald ; M. Watson ; D. J. Dooling ; D. Ota ; L. W. Chang ; R. Bose ; T. J. Ley ; D. Piwnica-Worms ; J. M. Stuart ; R. K. Wilson ; E. R. Mardis
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-06-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Androstadienes/pharmacology/therapeutic use ; Antineoplastic Agents/pharmacology/therapeutic use ; Aromatase/*metabolism ; Aromatase Inhibitors/*therapeutic use ; Breast Neoplasms/*drug therapy/*genetics/metabolism/pathology ; DNA Repair ; Exome/genetics ; Exons/genetics ; Female ; Genetic Variation/genetics ; Genome, Human/*genetics ; Humans ; MAP Kinase Kinase 4/genetics ; MAP Kinase Kinase Kinase 1/genetics ; Mutation/genetics ; Nitriles/pharmacology/therapeutic use ; Receptors, Estrogen/metabolism ; Treatment Outcome ; Triazoles/pharmacology/therapeutic use
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    M. Ablikim, M. N. Achasov, S. Ahmed, M. Albrecht, M. Alekseev, A. Amoroso, F. F. An, Q. An, Y. Bai, O. Bakina, R. Baldini Ferroli, Y. Ban, K. Begzsuren, D. W. Bennett, J. V. Bennett, N. Berger, M. Bertani, D. Bettoni, F. Bianchi, E. Boger, I. Boyko, R. A. Briere, H. Cai, X. Cai, O. Cakir, A. Calcaterra, G. F. Cao, S. A. Cetin, J. Chai, J. F. Chang, W. L. Chang, G. Chelkov, G. Chen, H. S. Chen, J. C. Chen, M. L. Chen, P. L. Chen, S. J. Chen, X. R. Chen, Y. B. Chen, X. K. Chu, G. Cibinetto, F. Cossio, H. L. Dai, J. P. Dai, A. Dbeyssi, D. Dedovich, Z. Y. Deng, A. Denig, I. Denysenko, M. Destefanis, F. De Mori, Y. Ding, C. Dong, J. Dong, L. Y. Dong, M. Y. Dong, Z. L. Dou, S. X. Du, P. F. Duan, J. Fang, S. S. Fang, Y. Fang, R. Farinelli, L. Fava, S. Fegan, F. Feldbauer, G. Felici, C. Q. Feng, E. Fioravanti, M. Fritsch, C. D. Fu, Q. Gao, X. L. Gao, Y. Gao, Y. G. Gao, Z. Gao, B. Garillon, I. Garzia, A. Gilman, K. Goetzen, L. Gong, W. X. Gong, W. Gradl, M. Greco, L. M. Gu, M. H. Gu, Y. T. Gu, A. Q. Guo, L. B. Guo, R. P. Guo, Y. P. Guo, A. Guskov, Z. Haddadi, S. Han, X. Q. Hao, F. A. Harris, K. L. He, X. Q. He, F. H. Heinsius, T. Held, Y. K. Heng, T. Holtmann, Z. L. Hou, H. M. Hu, J. F. Hu, T. Hu, Y. Hu, G. S. Huang, J. S. Huang, X. T. Huang, X. Z. Huang, Z. L. Huang, T. Hussain, W. Ikegami Andersson, M. Irshad, Q. Ji, Q. P. Ji, X. B. Ji, X. L. Ji, X. S. Jiang, X. Y. Jiang, J. B. Jiao, Z. Jiao, D. P. Jin, S. Jin, Y. Jin, T. Johansson, A. Julin, N. Kalantar-Nayestanaki, X. S. Kang, M. Kavatsyuk, B. C. Ke, T. Khan, A. Khoukaz, P. Kiese, R. Kliemt, L. Koch, O. B. Kolcu, B. Kopf, M. Kornicer, M. Kuemmel, M. Kuessner, A. Kupsc, M. Kurth, W. Kühn, J. S. Lange, M. Lara, P. Larin, L. Lavezzi, S. Leiber, H. Leithoff, C. Li, Cheng Li, D. M. Li, F. Li, F. Y. Li, G. Li, H. B. Li, H. J. Li, J. C. Li, J. W. Li, K. J. Li, Kang Li, Ke Li, Lei Li, P. L. Li, P. R. Li, Q. Y. Li, T. Li, W. D. Li, W. G. Li, X. L. Li, X. N. Li, X. Q. Li, Z. B. Li, H. Liang, Y. F. Liang, Y. T. Liang, G. R. Liao, L. Z. Liao, J. Libby, C. X. Lin, D. X. Lin, B. Liu, B. J. Liu, C. X. Liu, D. Liu, D. Y. Liu, F. H. Liu, Fang Liu, Feng Liu, H. B. Liu, H. L. Liu, H. M. Liu, Huanhuan Liu, Huihui Liu, J. B. Liu, J. Y. Liu, K. Liu, K. Y. Liu, Ke Liu, L. D. Liu, Q. Liu, S. B. Liu, X. Liu, Y. B. Liu, Z. A. Liu, Zhiqing Liu, Y. F. Long, X. C. Lou, H. J. Lu, J. G. Lu, Y. Lu, Y. P. Lu, C. L. Luo, M. X. Luo, X. L. Luo, S. Lusso, X. R. Lyu, F. C. Ma, H. L. Ma, L. L. Ma, M. M. Ma, Q. M. Ma, X. N. Ma, X. Y. Ma, Y. M. Ma, F. E. Maas, M. Maggiora, Q. A. Malik, A. Mangoni, Y. J. Mao, Z. P. Mao, S. Marcello, Z. X. Meng, J. G. Messchendorp, G. Mezzadri, J. Min, T. J. Min, R. E. Mitchell, X. H. Mo, Y. J. Mo, C. Morales Morales, G. Morello, N. Yu Muchnoi, H. Muramatsu, A. Mustafa, S. Nakhoul, Y. Nefedov, F. Nerling, I. B. Nikolaev, Z. Ning, S. Nisar, S. L. Niu, X. Y. Niu, S. L. Olsen, Q. Ouyang, S. Pacetti, Y. Pan, M. Papenbrock, P. Patteri, M. Pelizaeus, J. Pellegrino, H. P. Peng, Z. Y. Peng, K. Peters, J. Pettersson, J. L. Ping, R. G. Ping, A. Pitka, R. Poling, V. Prasad, H. R. Qi, M. Qi, T. Y. Qi, S. Qian, C. F. Qiao, N. Qin, X. S. Qin, Z. H. Qin, J. F. Qiu, K. H. Rashid, C. F. Redmer, M. Richter, M. Ripka, M. Rolo, G. Rong, Ch. Rosner, X. D. Ruan, A. Sarantsev, M. Savrié, C. Schnier, K. Schoenning, W. Shan, X. Y. Shan, M. Shao, C. P. Shen, P. X. Shen, X. Y. Shen, H. Y. Sheng, X. Shi, J. J. Song, W. M. Song, X. Y. Song, S. Sosio, C. Sowa, S. Spataro, G. X. Sun, J. F. Sun, L. Sun, S. S. Sun, X. H. Sun, Y. J. Sun, Y. K. Sun, Y. Z. Sun, Z. J. Sun, Z. T. Sun, Y. T. Tan, C. J. Tang, G. Y. Tang, X. Tang, I. Tapan, M. Tiemens, B. Tsednee, I. Uman, G. S. Varner, B. Wang, B. L. Wang, C. W. Wang, D. Wang, D. Y. Wang, Dan Wang, K. Wang, L. L. Wang, L. S. Wang, M. Wang, Meng Wang, P. Wang, P. L. Wang, W. P. Wang, X. F. Wang, Y. Wang, Y. F. Wang, Y. Q. Wang, Z. Wang, Z. G. Wang, Z. Y. Wang, Zongyuan Wang, T. Weber, D. H. Wei, P. Weidenkaff, S. P. Wen, U. Wiedner, M. Wolke, L. H. Wu, L. J. Wu, Z. Wu, L. Xia, X. Xia, Y. Xia, D. Xiao, Y. J. Xiao, Z. J. Xiao, Y. G. Xie, Y. H. Xie, X. A. Xiong, Q. L. Xiu, G. F. Xu, J. J. Xu, L. Xu, Q. J. Xu, Q. N. Xu, X. P. Xu, F. Yan, L. Yan, W. B. Yan, W. C. Yan, Y. H. Yan, H. J. Yang, H. X. Yang, L. Yang, S. L. Yang, Y. H. Yang, Y. X. Yang, Yifan Yang, M. Ye, M. H. Ye, J. H. Yin, Z. Y. You, B. X. Yu, C. X. Yu, J. S. Yu, C. Z. Yuan, Y. Yuan, A. Yuncu, A. A. Zafar, A. Zallo, Y. Zeng, Z. Zeng, B. X. Zhang, B. Y. Zhang, C. C. Zhang, D. H. Zhang, H. H. Zhang, H. Y. Zhang, J. Zhang, J. L. Zhang, J. Q. Zhang, J. W. Zhang, J. Y. Zhang, J. Z. Zhang, K. Zhang, L. Zhang, S. F. Zhang, T. J. Zhang, X. Y. Zhang, Y. Zhang, Y. H. Zhang, Y. T. Zhang, Yang Zhang, Yao Zhang, Yu Zhang, Z. H. Zhang, Z. P. Zhang, Z. Y. Zhang, G. Zhao, J. W. Zhao, J. Y. Zhao, J. Z. Zhao, Lei Zhao, Ling Zhao, M. G. Zhao, Q. Zhao, S. J. Zhao, T. C. Zhao, Y. B. Zhao, Z. G. Zhao, A. Zhemchugov, B. Zheng, J. P. Zheng, W. J. Zheng, Y. H. Zheng, B. Zhong, L. Zhou, Q. Zhou, X. Zhou, X. K. Zhou, X. R. Zhou, X. Y. Zhou, A. N. Zhu, J. Zhu, J. Zhu, K. Zhu, K. J. Zhu, S. Zhu, S. H. Zhu, X. L. Zhu, Y. C. Zhu, Y. S. Zhu, Z. A. Zhu, J. Zhuang, B. S. Zou, J. H. Zou and BESIII Collaboration
    Institute of Physics (IOP)
    Published 2018
    Staff View
    Publication Date:
    2018-06-02
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1674-1137
    Topics:
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    M. Ablikim, M. N. Achasov, S. Ahmed, M. Albrecht, M. Alekseev, A. Amoroso, F. F. An, Q. An, Y. Bai, O. Bakina, R. Baldini Ferroli, Y. Ban, K. Begzsuren, D. W. Bennett, J. V. Bennett, N. Berger, M. Bertani, D. Bettoni, J. M. Bian, F. Bianchi, E. Boger, I. Boyko, R. A. Briere, H. Cai, X. Cai, O. Cakir, A. Calcaterra, G. F. Cao, S. A. Cetin, J. Chai, J. F. Chang, W. L. Chang, G. Chelkov, G. Chen, H. S. Chen, J. C. Chen, M. L. Chen, P. L. Chen, S. J. Chen, X. R. Chen, Y. B. Chen, X. K. Chu, G. Cibinetto, F. Cossio, H. L. Dai, J. P. Dai, A. Dbeyssi, D. Dedovich, Z. Y. Deng, A. Denig, I. Denysenko, M. Destefanis, F. De Mori, Y. Ding, C. Dong, J. Dong, L. Y. Dong, M. Y. Dong, Z. L. Dou, S. X. Du, P. F. Duan, J. Fang, S. S. Fang, Y. Fang, R. Farinelli, L. Fava, S. Fegan, F. Feldbauer, G. Felici, C. Q. Feng, E. Fioravanti, M. Fritsch, C. D. Fu, Q. Gao, X. L. Gao, Y. Gao, Y. G. Gao, Z. Gao, B. Garillon, I. Garzia, A. Gilman, K. Goetzen, L. Gong, W. X. Gong, W. Gradl, M. Greco, L. M. Gu, M. H. Gu, Y. T. Gu, A. Q. Guo, L. B. Guo, R. P. Guo, Y. P. Guo, A. Guskov, Z. Haddadi, S. Han, X. Q. Hao, F. A. Harris, K. L. He, X. Q. He, F. H. Heinsius, T. Held, Y. K. Heng, T. Holtmann, Z. L. Hou, H. M. Hu, J. F. Hu, T. Hu, Y. Hu, G. S. Huang, J. S. Huang, X. T. Huang, X. Z. Huang, Z. L. Huang, T. Hussain, W. Ikegami Andersson, M Irshad, Q. Ji, Q. P. Ji, X. B. Ji, X. L. Ji, X. S. Jiang, X. Y. Jiang, J. B. Jiao, Z. Jiao, D. P. Jin, S. Jin, Y. Jin, T. Johansson, A. Julin, N. Kalantar-Nayestanaki, X. S. Kang, M. Kavatsyuk, B. C. Ke, T. Khan, A. Khoukaz, P. Kiese, R. Kliemt, L. Koch, O. B. Kolcu, B. Kopf, M. Kornicer, M. Kuemmel, M. Kuessner, A. Kupsc, M. Kurth, W. Kuhn, J. S. Lange, M. Lara, P. Larin, L. Lavezzi, S. Leiber, H. Leithoff, C. Li, Cheng Li, D. M. Li, F. Li, F. Y. Li, G. Li, H. B. Li, H. J. Li, J. C. Li, J. W. Li, K. J. Li, Kang Li, Ke Li, Lei Li, P. L. Li, P. R. Li, Q. Y. Li, T. Li, W. D. Li, W. G. Li, X. L. Li, X. N. Li, X. Q. Li, Z. B. Li, H. Liang, Y. F. Liang, Y. T. Liang, G. R. Liao, L. Z. Liao, J. Libby, C. X. Lin, D. X. Lin, B. Liu, B. J. Liu, C. X. Liu, D. Liu, D. Y. Liu, F. H. Liu, Fang Liu, Feng Liu, H. B. Liu, H. L Liu, H. M. Liu, Huanhuan Liu, Huihui Liu, J. B. Liu, J. Y. Liu, K. Liu, K. Y. Liu, Ke Liu, L. D. Liu, Q. Liu, S. B. Liu, X. Liu, Y. B. Liu, Z. A. Liu, Zhiqing Liu, Y. F. Long, X. C. Lou, H. J. Lu, J. G. Lu, Y. Lu, Y. P. Lu, C. L. Luo, M. X. Luo, X. L. Luo, S. Lusso, X. R. Lyu, F. C. Ma, H. L. Ma, L. L. Ma, M. M. Ma, Q. M. Ma, X. N. Ma, X. Y. Ma, Y. M. Ma, F. E. Maas, M. Maggiora, Q. A. Malik, A. Mangoni, Y. J. Mao, Z. P. Mao, S. Marcello, Z. X. Meng, J. G. Messchendorp, G. Mezzadri, J. Min, T. J. Min, R. E. Mitchell, X. H. Mo, Y. J. Mo, C. Morales Morales, G. Morello, N. Yu. Muchnoi, H. Muramatsu, A. Mustafa, S. Nakhoul, Y. Nefedov, F. Nerling, I. B. Nikolaev, Z. Ning, S. Nisar, S. L. Niu, X. Y. Niu, S. L. Olsen, Q. Ouyang, S. Pacetti, Y. Pan, M. Papenbrock, P. Patteri, M. Pelizaeus, J. Pellegrino, H. P. Peng, Z. Y. Peng, K. Peters, J. Pettersson, J. L. Ping, R. G. Ping, A. Pitka, R. Poling, V. Prasad, H. R. Qi, M. Qi, T. Y. Qi, S. Qian, C. F. Qiao, N. Qin, X. S. Qin, Z. H. Qin, J. F. Qiu, K. H. Rashid, C. F. Redmer, M. Richter, M. Ripka, M. Rolo, G. Rong, Ch. Rosner, X. D. Ruan, A. Sarantsev, M. Savrie, C. Schnier, K. Schoenning, W. Shan, X. Y. Shan, M. Shao, C. P. Shen, P. X. Shen, X. Y. Shen, H. Y. Sheng, X. Shi, J. J. Song, W. M. Song, X. Y. Song, S. Sosio, C. Sowa, S. Spataro, G. X. Sun, J. F. Sun, L. Sun, S. S. Sun, X. H. Sun, Y. J. Sun, Y. K Sun, Y. Z. Sun, Z. J. Sun, Z. T. Sun, Y. T Tan, C. J. Tang, G. Y. Tang, X. Tang, I. Tapan, M. Tiemens, D. Toth, B. Tsednee, I. Uman, G. S. Varner, B. Wang, B. L. Wang, C. W. Wang, D. Wang, D. Y. Wang, Dan Wang, K. Wang, L. L. Wang, L. S. Wang, M. Wang, Meng Wang, P. Wang, P. L. Wang, W. P. Wang, X. F. Wang, Y. Wang, Y. F. Wang, Y. Q. Wang, Z. Wang, Z. G. Wang, Z. Y. Wang, Zongyuan Wang, T. Weber, D. H. Wei, P. Weidenkaff, S. P. Wen, U. Wiedner, M. Wolke, L. H. Wu, L. J. Wu, Z. Wu, L. Xia, X. Xia, Y. Xia, D. Xiao, Y. J. Xiao, Z. J. Xiao, Y. G. Xie, Y. H. Xie, X. A. Xiong, Q. L. Xiu, G. F. Xu, J. J. Xu, L. Xu, Q. J. Xu, Q. N. Xu, X. P. Xu, F. Yan, L. Yan, W. B. Yan, W. C. Yan, Y. H. Yan, H. J. Yang, H. X. Yang, L. Yang, S. L. Yang, Y. H. Yang, Y. X. Yang, Yifan Yang, M. Ye, M. H. Ye, J. H. Yin, Z. Y. You, B. X. Yu, C. X. Yu, J. S. Yu, C. Z. Yuan, Y. Yuan, A. Yuncu, A. A. Zafar, A. Zallo, Y. Zeng, Z. Zeng, B. X. Zhang, B. Y. Zhang, C. C. Zhang, D. H. Zhang, H. H. Zhang, H. Y. Zhang, J. Zhang, J. L. Zhang, J. Q. Zhang, J. W. Zhang, J. Y. Zhang, J. Z. Zhang, K. Zhang, L. Zhang, S. F. Zhang, T. J. Zhang, X. Y. Zhang, Y. Zhang, Y. H. Zhang, Y. T. Zhang, Yang Zhang, Yao Zhang, Yu Zhang, Z. H. Zhang, Z. P. Zhang, Z. Y. Zhang, G. Zhao, J. W. Zhao, J. Y. Zhao, J. Z. Zhao, Lei Zhao, Ling Zhao, M. G. Zhao, Q. Zhao, S. J. Zhao, T. C. Zhao, Y. B. Zhao, Z. G. Zhao, A. Zhemchugov, B. Zheng, J. P. Zheng, W. J. Zheng, Y. H. Zheng, B. Zhong, L. Zhou, Q. Zhou, X. Zhou, X. K. Zhou, X. R. Zhou, X. Y. Zhou, A. N. Zhu, J. Zhu, J. Zhu, K. Zhu, K. J. Zhu, S. Zhu, S. H. Zhu, X. L. Zhu, Y. C. Zhu, Y. S. Zhu, Z. A. Zhu, J. Zhuang, B. S. Zou, J. H. Zou and BESIII Collaboration
    Institute of Physics (IOP)
    Published 2018
    Staff View
    Publication Date:
    2018-07-27
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1674-1137
    Topics:
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
  5. 5
  6. 6
  7. 7
    CHANG, L. W. S. ; MORITA, L. L. ; YAMAMOTO, H. Y.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1965
    Staff View
    ISSN:
    1750-3841
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Pectinesterase (PE) was inhibited by sucrose at the same concentrations that delayed gelation of papaya purée. The inhibitory effect was linear with sucrose concentration throughout the range investigated (up to 50% sucrose). Conditions for optimum PE activity, pH 7.5 and 0.21M NaCl, were not affected by inhibitory concentrations of sucrose. Evidence was obtained against competitive inhibition, transferase activity, and an effect on the binding of PE as possible mechanisms for inhibition. Other sugars tested, including glucose, maltose, and corn syrups of varying degrees of hydrolysis, as well as glycerol were also inhibitory.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Tsai, W. L. ; Hsu, P. C. ; Hwu, Y. ; Chen, C. H. ; Chang, L. W. ; Je, J. H. ; Lin, H. M. ; Groso, A. ; Margaritondo, G.

    [s.l.] : Nature Publishing Group
    Published 2002
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] In the electrodeposition of metals, a widely used industrial technique, bubbles of gas generated near the cathode can adversely affect the quality of the metal coating. Here we use phase-contrast radiology with synchrotron radiation to witness directly and in real time the accumulation of zinc ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Liu, K.-T. ; Chang, L.-W. ; Lee, S.-M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-4039
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Chang, L. W. ; Meier, J. R. ; Smith, M. K.
    Springer
    Published 1997
    Staff View
    ISSN:
    1432-0703
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Energy, Environment Protection, Nuclear Power Engineering
    Medicine
    Notes:
    Abstract. Earthworm acute toxicity, plant seed germination/root elongation (SG/RE) and plant genotoxicity bioassays were employed to evaluate the remediation of a lead-contaminated soil. The remediation involved removal of heavy metals by a soil washing/soil leaching treatment process. A portion of the soil after remediation was rinsed with water in order to simulate exposure to rainfall. The bioassay results showed that the soils before treatment (BT) and after treatment plus water rinsing (RT) were not toxic to earthworms in a 14-day exposure, while after treatment (AT) showed significant toxicity. The LC50 values for Eisenia fetida and Lumbricus terrestris were 44.04 and 28.83 (as % AT soil supplemented in artificial soil), respectively. The phytotoxicity data indicated that all three test soils significantly inhibited lettuce SG/RE in a dose-related manner, with AT being the most phytotoxic. In oats, RT had no effect on SG/RE and AT was more toxic than BT. For the two local site grass seeds tested (blue grama and sideoat grama), the AT soil was the most phytotoxic followed by BT and RT. In Allium cepa (common onion), BT and AT induced similar levels of genetic damage to root tip cells, whereas RT was not genotoxic. High salt levels generated during the remediation process appeared to be responsible for the increased toxicity of AT soil for both plants and earthworms. The rinsing of the AT soil with water effectively removed both acutely toxic and genotoxic components of the soil.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Chang, L. W. ; Hartmann, H. A.
    Springer
    Published 1972
    Staff View
    ISSN:
    1432-0533
    Keywords:
    Mercury Intoxication ; Nerve Cells ; Dorsal Root Ganglion ; Cerebellum ; Electron Microscopy
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary When given to rats, both organic and inorganic mercury compounds were found to be neurotoxic. After CH3HgCl intoxication, focal cytoplasmic degradation was the most characteristic lesion observed in the neurons of the dorsal root ganglion. A large cytoplasmic vacuole was formed in many neurons as a result of such lesions. After HgCl2 poisoning, the dorsal root ganglion neurons developed peripheral vacuoles, which were formed by the retraction of the neuron from its surrounding satellite cells. Extensive fragmentation of these neurons occurred as such vacuolation progressed. Multiple small lesions varying from 0.1–1.2 μ were found in the neuronal cytoplasm after both organic and inorganic mercury intoxication. Mercury could be demonstrated histochemically to have a close association with these lesions. In the anterior horn motoneurons, neither mercury compound produced any permanent pathological lesions in the nerve cell bodies, although there was severe dilatation of the cisternae of the endoplasmic reticulum and the nuclear envelope at early stages of the intoxication. In the cerebellum, both organic and inorganic mercury compounds produced extensive coagulative or lucid changes in the granule cells. Degeneration of the Purkinje cells was also found at late stages of the poisoning.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    1432-8798
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Infectious bovine rhinotracheitis virus (IBRV) has been shown in this report to have thirty-three polypeptides. Ten of the eleven polypeptides which can be labeled with (3H)-glucosamine are located on the surface of the virus since they can be surface labeled with sodium boro(3H)hydride. In order to define the immunologically important viral proteins, monoclonal antibodies were prepared against the virus and selected for their ability to neutralize infectivity. Four such hybridoma lines were obtained for characterization of the antigens that elicit neutralizing antibodies. The viral polypeptides were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and the specificity of each monoclonal antibody was determined by “Western” blot analysis and/or by immunoprecipitation of (35S)-methionine and (3H)-glucosamine labeled infected cell lysates by the monoclonal antibodies. One monoclonal antibody reacted with two glycoproteins, gp135 and gp78a, on the “Western” blot but immunoprecipitated three glycoproteins, gp135, gp78a, and gp54 from labeled infected cell lysates. The other three monoclonal antibodies immunoprecipitated a single glycoprotein, gp78b, from (3H)-glucosamine labeled infected cell lysates but not from (35S)-methionine labeled infected cell lysates.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses