ILSE | Search Results - (Author, Cooperation:L. Roth)

1

Jupiter's aurora observed with HST during Juno orbits 3 to 7

Grodent Denis, B. Bonfond, Z. Yao, J.-C. Gérard, A. Radioti, M. Dumont, B. Palmaerts, A. Adriani, S. V. Badman, E. J. Bunce, J. T. Clarke, J. E. P. Connerney, G. R. Gladstone, T. Greathouse, T. Kimura, W. S. Kurth, B. H. Mauk, D. J. McComas, J. D. Nichols, G. S. Orton, L. Roth, J. Saur, P. Valek
Wiley-Blackwell
Published 2018

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Publication Date:	2018-03-13
Publisher:	Wiley-Blackwell
Print ISSN:	0148-0227
Topics:	Geosciences Physics
Published by:	http://www.wiley.com/wiley-blackwell

Latest Papers from Table of Contents or Articles in Press

2

The influence of spatiotemporally decoupled land use on honey bee colony health and pollination service delivery

Matthew D Smart, Clint R V Otto, Benjamin L Carlson and Cali L Roth
Institute of Physics (IOP)
Published 2018

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Publication Date:	2018-08-02
Publisher:	Institute of Physics (IOP)
Print ISSN:	1748-9318
Electronic ISSN:	1748-9326
Topics:	Biology Energy, Environment Protection, Nuclear Power Engineering
Published by:	http://www.iop.org/

Latest Papers from Table of Contents or Articles in Press

3

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

H. S. Huang ; J. A. Allen ; A. M. Mabb ; I. F. King ; J. Miriyala ; B. Taylor-Blake ; N. Sciaky ; J. W. Dutton, Jr. ; H. M. Lee ; X. Chen ; J. Jin ; A. S. Bridges ; M. J. Zylka ; B. L. Roth ; B. D. Philpot
Nature Publishing Group (NPG)
Published 2011

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Publication Date:	2011-12-23
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Alleles ; Angelman Syndrome/drug therapy/genetics ; Animals ; Cells, Cultured ; Cerebral Cortex/cytology/drug effects/metabolism ; Drug Evaluation, Preclinical ; Fathers ; Female ; Gene Silencing/drug effects ; Genomic Imprinting/drug effects/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mothers ; Neurons/drug effects/metabolism ; Small Molecule Libraries/administration & dosage/chemistry/pharmacology ; Topoisomerase Inhibitors/administration & ; dosage/analysis/pharmacokinetics/pharmacology ; Topotecan/administration & dosage/pharmacokinetics/pharmacology ; Ubiquitin-Protein Ligases/deficiency/genetics
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

4

Global landscape of HIV-human protein complexes

S. Jager ; P. Cimermancic ; N. Gulbahce ; J. R. Johnson ; K. E. McGovern ; S. C. Clarke ; M. Shales ; G. Mercenne ; L. Pache ; K. Li ; H. Hernandez ; G. M. Jang ; S. L. Roth ; E. Akiva ; J. Marlett ; M. Stephens ; I. D'Orso ; J. Fernandes ; M. Fahey ; C. Mahon ; A. J. O'Donoghue ; A. Todorovic ; J. H. Morris ; D. A. Maltby ; T. Alber ; G. Cagney ; F. D. Bushman ; J. A. Young ; S. K. Chanda ; W. I. Sundquist ; T. Kortemme ; R. D. Hernandez ; C. S. Craik ; A. Burlingame ; A. Sali ; A. D. Frankel ; N. J. Krogan
Nature Publishing Group (NPG)
Published 2011

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Publication Date:	2011-12-23
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Affinity Labels ; Amino Acid Sequence ; Conserved Sequence ; Eukaryotic Initiation Factor-3/chemistry/metabolism ; HEK293 Cells ; HIV Infections/metabolism/virology ; HIV Protease/metabolism ; HIV-1/chemistry/metabolism/physiology ; Host-Pathogen Interactions ; Human Immunodeficiency Virus Proteins/analysis/chemistry/isolation & ; purification/metabolism ; Humans ; Immunoprecipitation ; Jurkat Cells ; Mass Spectrometry ; Protein Binding ; Protein Interaction Mapping/methods ; Protein Interaction Maps/physiology ; Reproducibility of Results ; Virus Replication
Published by:	http://www.nature.com/

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5

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

X. P. Huang ; J. Karpiak ; W. K. Kroeze ; H. Zhu ; X. Chen ; S. S. Moy ; K. A. Saddoris ; V. D. Nikolova ; M. S. Farrell ; S. Wang ; T. J. Mangano ; D. A. Deshpande ; A. Jiang ; R. B. Penn ; J. Jin ; B. H. Koller ; T. Kenakin ; B. K. Shoichet ; B. L. Roth
Nature Publishing Group (NPG)
Published 2015

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Publication Date:	2015-11-10
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Allosteric Regulation/drug effects ; Allosteric Site ; Animals ; Anti-Anxiety Agents/analysis/chemistry/metabolism/pharmacology ; Benzyl Alcohols/analysis/chemistry/metabolism/pharmacology ; Conditioning, Classical ; Drug Discovery ; Fear ; Female ; HEK293 Cells ; Humans ; Ligands ; Lorazepam/analysis/chemistry/metabolism/pharmacology ; Male ; Memory/drug effects ; Mice ; Mice, Knockout ; Models, Molecular ; Receptors, G-Protein-Coupled/agonists/antagonists & ; inhibitors/chemistry/deficiency/metabolism ; Signal Transduction/drug effects ; Triazines/analysis/chemistry/metabolism/pharmacology
Published by:	http://www.nature.com/

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6

[ASAP] Selectivity Challenges in Docking Screens for GPCR Targets and Antitargets

Dahlia R. Weiss, Joel Karpiak, Xi-Ping Huang, Maria F. Sassano, Jiankun Lyu, Bryan L. Roth, Brian K. Shoichet
American Chemical Society (ACS)
Published 2018

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Publication Date:	2018-07-25
Publisher:	American Chemical Society (ACS)
Topics:	Chemistry and Pharmacology
Published by:	http://www.acs.org/

Latest Papers from Table of Contents or Articles in Press

7

Structure of the human smoothened receptor bound to an antitumour agent

C. Wang ; H. Wu ; V. Katritch ; G. W. Han ; X. P. Huang ; W. Liu ; F. Y. Siu ; B. L. Roth ; V. Cherezov ; R. C. Stevens
Nature Publishing Group (NPG)
Published 2013

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Publication Date:	2013-05-03
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Motifs ; Amino Acid Sequence ; Antineoplastic Agents/chemistry/metabolism ; Binding Sites ; Crystallography, X-Ray ; Disulfides/chemistry ; Frizzled Receptors/chemistry/classification ; Humans ; Ligands ; Models, Molecular ; Molecular Sequence Data ; Phthalazines/chemistry/metabolism ; Protein Structure, Tertiary ; Receptors, G-Protein-Coupled/*chemistry/classification/metabolism ; Structural Homology, Protein
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

8

Structural basis for molecular recognition at serotonin receptors

C. Wang ; Y. Jiang ; J. Ma ; H. Wu ; D. Wacker ; V. Katritch ; G. W. Han ; W. Liu ; X. P. Huang ; E. Vardy ; J. D. McCorvy ; X. Gao ; X. E. Zhou ; K. Melcher ; C. Zhang ; F. Bai ; H. Yang ; L. Yang ; H. Jiang ; B. L. Roth ; V. Cherezov ; R. C. Stevens ; H. E. Xu
American Association for the Advancement of Science (AAAS)
Published 2013

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Publication Date:	2013-03-23
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Sequence ; Binding Sites ; Crystallography, X-Ray ; Dihydroergotamine/chemistry/metabolism ; Ergotamine/chemistry/metabolism ; Humans ; Hydrogen Bonding ; Hydrophobic and Hydrophilic Interactions ; Ligands ; Lysergic Acid Diethylamide/chemistry/metabolism ; Models, Molecular ; Molecular Docking Simulation ; Molecular Sequence Data ; Mutagenesis ; Norfenfluramine/chemistry/metabolism ; Pindolol/analogs & derivatives/chemistry/metabolism ; Propranolol/chemistry/metabolism ; Protein Conformation ; Protein Folding ; Protein Structure, Secondary ; Receptor, Serotonin, 5-HT1B/chemistry/genetics/metabolism ; Serotonin 5-HT1 Receptor Agonists/chemistry/metabolism ; Tryptamines/chemistry/metabolism
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

9

Transient water vapor at Europa's south pole

L. Roth ; J. Saur ; K. D. Retherford ; D. F. Strobel ; P. D. Feldman ; M. A. McGrath ; F. Nimmo
American Association for the Advancement of Science (AAAS)
Published 2013

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Publication Date:	2013-12-18
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

10

Generation of a synthetic memory trace

A. R. Garner ; D. C. Rowland ; S. Y. Hwang ; K. Baumgaertel ; B. L. Roth ; C. Kentros ; M. Mayford
American Association for the Advancement of Science (AAAS)
Published 2012

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Publication Date:	2012-03-24
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Amygdala/physiology ; Animals ; Behavior, Animal ; Brain/physiology ; CA1 Region, Hippocampal/physiopathology ; Clozapine/analogs & derivatives/pharmacology ; Conditioning (Psychology) ; Cues ; Electroshock ; Fear ; Genes, fos ; Learning ; Memory ; Mental Recall ; Mice ; Mice, Transgenic ; Nerve Net/physiology ; Neurons/physiology ; Promoter Regions, Genetic ; Receptor, Muscarinic M3/genetics/metabolism
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

11

[ASAP] Phosphoproteomics Illuminates Opioid Actions

Tao Che, Bryan L. Roth
American Chemical Society (ACS)
Published 2018

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Publication Date:	2018-09-14
Publisher:	American Chemical Society (ACS)
Print ISSN:	0006-2960
Electronic ISSN:	1520-4995
Topics:	Biology Chemistry and Pharmacology
Published by:	http://www.acs.org/

Latest Papers from Table of Contents or Articles in Press

12

Structural features for functional selectivity at serotonin receptors

D. Wacker ; C. Wang ; V. Katritch ; G. W. Han ; X. P. Huang ; E. Vardy ; J. D. McCorvy ; Y. Jiang ; M. Chu ; F. Y. Siu ; W. Liu ; H. E. Xu ; V. Cherezov ; B. L. Roth ; R. C. Stevens
American Association for the Advancement of Science (AAAS)
Published 2013

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Publication Date:	2013-03-23
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Motifs ; Amino Acid Sequence ; Arrestin/metabolism ; Arrestins/metabolism ; Binding Sites ; Crystallography, X-Ray ; Ergolines/chemistry/metabolism ; Ergotamine/chemistry/metabolism ; HEK293 Cells ; Humans ; Ligands ; Lysergic Acid Diethylamide/chemistry/metabolism ; Models, Molecular ; Molecular Sequence Data ; Protein Conformation ; Protein Structure, Secondary ; Receptor, Serotonin, 5-HT1B/chemistry/metabolism ; Receptor, Serotonin, 5-HT2B/chemistry/metabolism ; Receptors, Serotonin/chemistry/metabolism ; Signal Transduction
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

13

Molecular control of delta-opioid receptor signalling

G. Fenalti ; P. M. Giguere ; V. Katritch ; X. P. Huang ; A. A. Thompson ; V. Cherezov ; B. L. Roth ; R. C. Stevens
Nature Publishing Group (NPG)
Published 2014

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Publication Date:	2014-01-15
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Allosteric Regulation/drug effects/genetics ; Allosteric Site/drug effects/genetics ; Arrestins/metabolism ; Asparagine/genetics/metabolism ; Crystallography, X-Ray ; Humans ; Ligands ; Models, Molecular ; Mutagenesis, Site-Directed ; Naltrexone/analogs & derivatives/chemistry/metabolism/pharmacology ; Narcotic Antagonists/chemistry/metabolism/pharmacology ; Receptors, Opioid, delta/agonists/antagonists & ; inhibitors/chemistry/genetics/metabolism ; *Signal Transduction/drug effects ; Sodium/metabolism/pharmacology ; Structure-Activity Relationship
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

14

Transcranial amelioration of inflammation and cell death after brain injury

T. L. Roth ; D. Nayak ; T. Atanasijevic ; A. P. Koretsky ; L. L. Latour ; D. B. McGavern
Nature Publishing Group (NPG)
Published 2013

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Publication Date:	2013-12-10
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Administration, Topical ; Animals ; Antioxidants/administration & dosage/therapeutic use ; Astrocytes/pathology ; Brain/drug effects/pathology ; Brain Injuries/complications/diagnosis/drug therapy/pathology ; Cell Death/drug effects ; Disease Models, Animal ; Encephalitis/complications/drug therapy/pathology/prevention & control ; Glasgow Coma Scale ; Glutathione/administration & dosage/therapeutic use ; Humans ; Intracranial Hemorrhages/complications/diagnosis ; Male ; Meninges/drug effects/pathology ; Mice ; Microglia/cytology/drug effects/physiology ; Neuroprotective Agents/administration & dosage/therapeutic use ; Neutrophils/drug effects/physiology ; Purinergic P2 Receptor Antagonists/administration & ; dosage/pharmacology/therapeutic use ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Receptors, Purinergic P2/metabolism ; Receptors, Purinergic P2X7/metabolism ; Skull/metabolism
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

15

Automated design of ligands to polypharmacological profiles

J. Besnard ; G. F. Ruda ; V. Setola ; K. Abecassis ; R. M. Rodriguiz ; X. P. Huang ; S. Norval ; M. F. Sassano ; A. I. Shin ; L. A. Webster ; F. R. Simeons ; L. Stojanovski ; A. Prat ; N. G. Seidah ; D. B. Constam ; G. R. Bickerton ; K. D. Read ; W. C. Wetsel ; I. H. Gilbert ; B. L. Roth ; A. L. Hopkins
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-12-14
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Animals ; Automation ; Drug Delivery Systems ; Drug Design ; Female ; Ligands ; Male ; Mice ; Mice, Inbred C57BL ; Models, Theoretical ; Pharmacological Phenomena ; Reproducibility of Results
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

16

Structure of the human kappa-opioid receptor in complex with JDTic

H. Wu ; D. Wacker ; M. Mileni ; V. Katritch ; G. W. Han ; E. Vardy ; W. Liu ; A. A. Thompson ; X. P. Huang ; F. I. Carroll ; S. W. Mascarella ; R. B. Westkaemper ; P. D. Mosier ; B. L. Roth ; V. Cherezov ; R. C. Stevens
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-03-23
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Binding Sites ; Crystallography, X-Ray ; Diterpenes, Clerodane/chemistry/metabolism/pharmacology ; Guanidines/chemistry ; Humans ; Models, Molecular ; Morphinans/chemistry ; Mutagenesis, Site-Directed ; Naltrexone/analogs & derivatives/chemistry/metabolism ; Piperidines/chemistry/pharmacology ; Protein Conformation ; Receptors, Adrenergic, beta-2/chemistry ; Receptors, CXCR4/chemistry/metabolism ; Receptors, Opioid, kappa/antagonists & inhibitors/chemistry/genetics/metabolism ; Structure-Activity Relationship ; Tetrahydroisoquinolines/chemistry/pharmacology
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

17

NOBEL 2012 Chemistry: Studies of a ubiquitous receptor family

B. L. Roth ; F. H. Marshall
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-12-12
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Biochemistry/history ; Chemistry/history ; Drug Discovery/history ; High-Throughput Screening Assays/history ; History, 20th Century ; History, 21st Century ; Humans ; Nobel Prize ; Receptors, G-Protein-Coupled/genetics/isolation & purification/*metabolism ; Structure-Activity Relationship
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

18

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

A. A. Thompson ; W. Liu ; E. Chun ; V. Katritch ; H. Wu ; E. Vardy ; X. P. Huang ; C. Trapella ; R. Guerrini ; G. Calo ; B. L. Roth ; V. Cherezov ; R. C. Stevens
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-05-19
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Binding Sites ; Biomimetic Materials/chemistry/metabolism/pharmacology ; Crystallography, X-Ray ; HEK293 Cells ; Humans ; Ligands ; Models, Molecular ; Narcotic Antagonists ; Opioid Peptides/chemistry/metabolism/pharmacology ; Piperidines/chemistry/metabolism/pharmacology ; Protein Conformation ; Receptors, Opioid/chemistry/metabolism ; Receptors, Opioid, kappa/chemistry/metabolism ; Spiro Compounds/chemistry/metabolism/pharmacology ; Substrate Specificity
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

19

Vascular smooth muscle cell death, autophagy and senescence in atherosclerosis

Grootaert M, Moulis M, Roth L, et al.
Oxford University Press
Published 2018

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Publication Date:	2018-03-06
Publisher:	Oxford University Press
Print ISSN:	0008-6363
Electronic ISSN:	1755-3245
Topics:	Medicine
Published by:	http://global.oup.com/

Latest Papers from Table of Contents or Articles in Press

20

How I treat primary mediastinal B-cell lymphoma

Giulino-Roth, L.
American Society of Hematology (ASH)
Published 2018

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Publication Date:	2018-08-24
Publisher:	American Society of Hematology (ASH)
Print ISSN:	0006-4971
Electronic ISSN:	1528-0020
Topics:	Biology Medicine
Keywords:	How I Treat, Free Research Articles, Lymphoid Neoplasia
Published by:	http://www.hematology.org/

Latest Papers from Table of Contents or Articles in Press

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