Search Results - (Author, Cooperation:L. R. Doyle)

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  1. 1
    Staff View
    Publication Date:
    2012-01-13
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Extraterrestrial Environment/chemistry ; *Planets ; Space Flight ; Spacecraft ; Stars, Celestial
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2011-09-17
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2012-08-31
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Robertson, G. H. ; Doyle, L. R. ; Sheng, P. ; Pavlath, A. E. ; Goodman, N.

    New York, NY [u.a.] : Wiley-Blackwell
    Published 1989
    Staff View
    ISSN:
    0006-3592
    Keywords:
    Chemistry ; Biochemistry and Biotechnology
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Biology
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Altered phosphorus concentration, oxygen supply rate, and programmed addition of sucrose and phosphorus were applied to Dioscorea deltoidea plant cells in airlift suspension to increase the formation of the secondary metabolite diosgenin. A low oxygen supply rate (kla′ of 3.9 h-1) completely inhibited formation of diosgenin. A high oxygen supply rate (kla′ of 17.1 h-1) led to the greatest formation of diosgenin in 30 g/L sucrose when the sucrose-to-phosphorus mole ratio was 42.5:1. Programmed addition of nutrients over a 15-day period reduced growth of cell mass relative to diosgenin mass. Intentional aggregation by entrapment of virtually all cells in reticulated polyurethane foam led to reduced cell-mass yield, diosgenin yield and concentration relative to suspended cells at the same conditions. Entrapment of a small fraction of the cells led to a delayed development of a suspension culture and to formation of significantly higher concentrations of diosgenin. Nearly all of this increase was attributable to the suspended cells. This result suggested sequestering of nonproductive cells by the matrix or sequestering of important nutrients by the matrix-bound cells. Entrapped cells attained densities of 40 g/L in the matrix.
    Additional Material:
    10 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses