Search Results - (Author, Cooperation:L. R. Cardon)

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  1. 1
    Staff View
    Publication Date:
    2012-05-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    African Americans/genetics ; Asian Continental Ancestry Group ; Disease/*genetics ; European Continental Ancestry Group/genetics ; Gene Frequency ; Genetic Association Studies ; Genetic Predisposition to Disease ; *Genetic Variation ; *Genome, Human ; Geography ; High-Throughput Nucleotide Sequencing ; Humans ; Molecular Targeted Therapy ; Multifactorial Inheritance ; Mutation Rate ; Pharmacogenetics ; Phenotype ; Polymorphism, Single Nucleotide ; Population Growth ; Sample Size ; Selection, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    1573-0905
    Keywords:
    multiple regression ; quantitative trait loci ; sib-pair data ; reading disability ; linkage analysis
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Education
    Notes:
    Abstract A simple extension of the DeFries and Fulker multiple regression model for twin analysis is applied to the problem of detecting linkage in a quantitative trait. The method, employing sib pairs, is based on that of Haseman and Elston. Reading data from 19 extended pedigrees were analyzed employing RLFPs as markers on chromosome 15 and using the widely available statistical applications software package, SAS. A number of possible linkages were detected, indicating that this approach is both powerful and effective, especially in the case of selected samples. Detecting genotype-environment interaction and the issue of power are briefly discussed. The programs used are available upon request.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  3. 3
    Staff View
    ISSN:
    1573-3297
    Keywords:
    differential heritability ; differential shared environmentality ; cognitive ability ; twins
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Psychology
    Notes:
    Abstract Differences in heritability and shared environmentality across levels of cognitive ability were assessed in a sample of 264 twin pairs tested at 1 year of age and in subsets tested at 2 and 3 years. Using an extension of the DF multiple regression methodology for analyzing twin data, no evidence was found for a linear or quadratic effect of level of cognitive ability on estimates of heritability or shared environmentality.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses