Search Results - (Author, Cooperation:L. Pasquier)

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  1. 1
    S. Jacquemont ; A. Reymond ; F. Zufferey ; L. Harewood ; R. G. Walters ; Z. Kutalik ; D. Martinet ; Y. Shen ; A. Valsesia ; N. D. Beckmann ; G. Thorleifsson ; M. Belfiore ; S. Bouquillon ; D. Campion ; N. de Leeuw ; B. B. de Vries ; T. Esko ; B. A. Fernandez ; F. Fernandez-Aranda ; J. M. Fernandez-Real ; M. Gratacos ; A. Guilmatre ; J. Hoyer ; M. R. Jarvelin ; R. F. Kooy ; A. Kurg ; C. Le Caignec ; K. Mannik ; O. S. Platt ; D. Sanlaville ; M. M. Van Haelst ; S. Villatoro Gomez ; F. Walha ; B. L. Wu ; Y. Yu ; A. Aboura ; M. C. Addor ; Y. Alembik ; S. E. Antonarakis ; B. Arveiler ; M. Barth ; N. Bednarek ; F. Bena ; S. Bergmann ; M. Beri ; L. Bernardini ; B. Blaumeiser ; D. Bonneau ; A. Bottani ; O. Boute ; H. G. Brunner ; D. Cailley ; P. Callier ; J. Chiesa ; J. Chrast ; L. Coin ; C. Coutton ; J. M. Cuisset ; J. C. Cuvellier ; A. David ; B. de Freminville ; B. Delobel ; M. A. Delrue ; B. Demeer ; D. Descamps ; G. Didelot ; K. Dieterich ; V. Disciglio ; M. Doco-Fenzy ; S. Drunat ; B. Duban-Bedu ; C. Dubourg ; J. S. El-Sayed Moustafa ; P. Elliott ; B. H. Faas ; L. Faivre ; A. Faudet ; F. Fellmann ; A. Ferrarini ; R. Fisher ; E. Flori ; L. Forer ; D. Gaillard ; M. Gerard ; C. Gieger ; S. Gimelli ; G. Gimelli ; H. J. Grabe ; A. Guichet ; O. Guillin ; A. L. Hartikainen ; D. Heron ; L. Hippolyte ; M. Holder ; G. Homuth ; B. Isidor ; S. Jaillard ; Z. Jaros ; S. Jimenez-Murcia ; G. J. Helas ; P. Jonveaux ; S. Kaksonen ; B. Keren ; A. Kloss-Brandstatter ; N. V. Knoers ; D. A. Koolen ; P. M. Kroisel ; F. Kronenberg ; A. Labalme ; E. Landais ; E. Lapi ; V. Layet ; S. Legallic ; B. Leheup ; B. Leube ; S. Lewis ; J. Lucas ; K. D. MacDermot ; P. Magnusson ; C. Marshall ; M. Mathieu-Dramard ; M. I. McCarthy ; T. Meitinger ; M. A. Mencarelli ; G. Merla ; A. Moerman ; V. Mooser ; F. Morice-Picard ; M. Mucciolo ; M. Nauck ; N. C. Ndiaye ; A. Nordgren ; L. Pasquier ; F. Petit ; R. Pfundt ; G. Plessis ; E. Rajcan-Separovic ; G. P. Ramelli ; A. Rauch ; R. Ravazzolo ; A. Reis ; A. Renieri ; C. Richart ; J. S. Ried ; C. Rieubland ; W. Roberts ; K. M. Roetzer ; C. Rooryck ; M. Rossi ; E. Saemundsen ; V. Satre ; C. Schurmann ; E. Sigurdsson ; D. J. Stavropoulos ; H. Stefansson ; C. Tengstrom ; U. Thorsteinsdottir ; F. J. Tinahones ; R. Touraine ; L. Vallee ; E. van Binsbergen ; N. Van der Aa ; C. Vincent-Delorme ; S. Visvikis-Siest ; P. Vollenweider ; H. Volzke ; A. T. Vulto-van Silfhout ; G. Waeber ; C. Wallgren-Pettersson ; R. M. Witwicki ; S. Zwolinksi ; J. Andrieux ; X. Estivill ; J. F. Gusella ; O. Gustafsson ; A. Metspalu ; S. W. Scherer ; K. Stefansson ; A. I. Blakemore ; J. S. Beckmann ; P. Froguel
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-09-02
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adolescent ; Adult ; Aged ; Aging ; Body Height/genetics ; *Body Mass Index ; Case-Control Studies ; Child ; Child, Preschool ; Chromosomes, Human, Pair 16/*genetics ; Cohort Studies ; Comparative Genomic Hybridization ; Developmental Disabilities/genetics ; Energy Metabolism/genetics ; Europe ; Female ; Gene Dosage/*genetics ; Gene Duplication/genetics ; Gene Expression Profiling ; Genetic Predisposition to Disease/genetics ; Genome-Wide Association Study ; Head/anatomy & histology ; Heterozygote ; Humans ; Infant ; Infant, Newborn ; Male ; Mental Disorders/genetics ; Middle Aged ; Mutation/genetics ; North America ; Obesity/*genetics ; *Phenotype ; RNA, Messenger/analysis/genetics ; Sequence Deletion/genetics ; Thinness/*genetics ; Transcription, Genetic ; Young Adult
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Miguet, M., Faivre, L., Amiel, J., Nizon, M., Touraine, R., Prieur, F., Pasquier, L., Lefebvre, M., Thevenon, J., Dubourg, C., Julia, S., Sarret, C., Remerand, G., Francannet, C., Laffargue, F., Boespflug-Tanguy, O., David, A., Isidor, B., Vigneron, J., Leheup, B., Lambert, L., Philippe, C., Beri-Dexheimer, M., Cuisset, J.-M., Andrieux, J., Plessis, G., Toutain, A., Guibaud, L., Cormier-Daire, V., Rio, M., Bonnefont, J.-P., Echenne, B., Journel, H., Burglen, L., Chantot-Bastaraud, S., Bienvenu, T., Baumann, C., Perrin, L., Drunat, S., Jouk, P.-S., Dieterich, K., Devillard, F., Lacombe, D., Philip, N., Sigaudy, S., Moncla, A., Missirian, C., Badens, C., Perreton, N., Thauvin-Robinet, C., AChro-Puce, R., Pedespan, J.-M., Rooryck, C., Goizet, C., Vincent-Delorme, C., Duban-Bedu, B., Bahi-Buisson, N., Afenjar, A., Maincent, K., Heron, D., Alessandri, J.-L., Martin-Coignard, D., Lesca, G., Rossi, M., Raynaud, M., Callier, P., Mosca-Boidron, A.-L., Marle, N., Coutton, C., Satre, V., Caignec, C. L., Malan, V., Romana, S., Keren, B., Tabet, A.-C., Kremer, V., Scheidecker, S., Vigouroux, A., Lackmy-Port-Lis, M., Sanlaville, D., Till, M., Carneiro, M., Gilbert-Dussardier, B., Willems, M., Van Esch, H., Portes, V. D., El Chehadeh, S.
    BMJ Publishing Group
    Published 2018
    Staff View
    Publication Date:
    2018-05-26
    Publisher:
    BMJ Publishing Group
    Print ISSN:
    0022-2593
    Electronic ISSN:
    1468-6244
    Topics:
    Medicine
    Keywords:
    Editor's choice
    Published by:
    http://www.bmj.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Du Pasquier, L.

    Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.
    Published 2005
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    An ideal immune system should provide each individual with rapid and efficient responses, a diverse repertoire of recognition and effector molecules and a certain flexibility to match the changing internal and external environment. It should be economic in cells and genes. Specific memory would be useful. It should not be autoreactive. These requirements, a mixture of innate and adaptive immunity features, are modulated in function of the dominant mode of selection for each species of metazoa during evolution (K or r). From sponges to man, a great diversity of receptors and effector mechanisms, some of them shared with plants, are articulated around conserved signalling cascades. Multiple attempts at combining innate and adaptive immunity somatic features can be observed as new somatic mechanisms provide individualized repertoires of receptors throughout metazoa, in agnathans, prochordates, echinoderms and mollusks. The adaptive immunity of vertebrates with lymphocytes and their specific receptors of the immunoglobulin superfamily, the major histocompatibility complex, developed from innate immunity evolutionary lines that can be traced back in earlier deuterostomes.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-3083.2005.01608.x

    Articles: DFG German National Licenses
  4. 4
    Passeron, T. ; Imbert, P. ; Colbacchini, P. ; Dosseh, A. ; Pasquier, L. ; Kâ, A.S. ; Lacour, J.P.H.

    Oxford, UK : Blackwell Science Ltd
    Published 2003
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2133.2003.05608.x

    Articles: DFG German National Licenses
  5. 5
    WABL, M. R. ; Du PASQUIER, L.

    [s.l.] : Nature Publishing Group
    Published 1976
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Crosses of X. laevis (L) with X. gilli (G) yield female (LG) offspring which lay diploid eggs, the genome of which is identical to that of the mothers. The gynogenetic development (that from the female pronucleus alone) of these eggs gives rise to individuals which are genetically identical; that ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/264642a0

    Articles: DFG German National Licenses
  6. 6
    Flajnik, M.F. ; Du Pasquier, L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0012-1606
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0012-1606(88)90282-5

    Articles: DFG German National Licenses
  7. 7
    Pasquier, L. ; Miggiano, V. C. ; Kobel, H. R. ; Fischberg, M.
    Springer
    Published 1977
    Staff View
    ISSN:
    1432-1211
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract Family studies inXenopus laevis (2n=36 chromosomes) demonstrate the expression of a single major histocompatibility complex in this species. Mixed leukocyte studies in two families ofXenopus vestitus (2n=72 chromosomes) indicated that this reaction was also under the control of a single genetic region. These studies suggest that, in this polyploid species, the switch from tetrasomic to disomic inheritance has already been accomplished for this locus. In contrast, segregation of mixed leukocyte reaction determinants and patterns of graft rejection in two families ofXenopus ruwenzoriensis (2n=108 chromosomes) were incompatible with the expression of a single major histocompatibility complex, and suggest that polysomic inheritance of this locus is maintained in this species. This interpretation was confirmed by the finding in a sibship of hybrids betweenXenopus ruwenzoriensis andXenopus laevis (2n=54+18) of more than four classes of mixed leukocyte reaction-identical sibs. In laboratory-created triploid animals (trispecies hybrid amongXenopus laevis, Xenopus gilli, andXenopus clivii), mixed leukocyte reaction and grafting experiments demonstrated that the major histocompatibility complex of each constituting species was codominantly expressed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01570469

    Articles: DFG German National Licenses
  8. 8
    Kobel, H.R. ; Du Pasquier, L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0168-9525
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0168-9525(86)90286-6

    Articles: DFG German National Licenses
  9. 9
    Pasquier, L. ; Horton, J. D.
    Springer
    Published 1976
    Staff View
    ISSN:
    1432-1211
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract In the clawed toadXenopus laevis, thymectomy at 7 days of age abrogates the phytohemagglutinin response of leukocytes and the mixed leukocyte reaction.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01576943

    Articles: DFG German National Licenses
  10. 10
    Pasquier, L. ; Chardonnens, X. ; Miggiano, V. C.
    Springer
    Published 1974
    Staff View
    ISSN:
    1432-1211
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract The genetic relationship between mixed leukocyte reaction (MLR), skin graft rejection, and some red blood cell antigens has been studied in a sibship of the toadXenopus laevis. MLR typing was achieved using blood lymphocytes. The graft experiments were performed at 17–19°C. Grafts exchanged between MLR identical sibs were rejected in 30.9±5.1 days, grafts exchanged between MLR different sibs were rejected in 20.4±2.4 days when animals differed at one MLR haplotype, and in 18.6±1.9 days when they differed at two MLR haplotypes. Immunizations and absorptions following the MLR typing produced agglutinating antisera that recognize red blood cell antigens segregating with MLR haplotypes. The results parallel those obtained in various mammalian and avian species and suggest that the homology of the major histocompatibility complex (MHC), described in higher vertebrates, can be extended to amphibians.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01564086

    Articles: DFG German National Licenses
  11. 11
    Kobel, H. R. ; Pasquier, L.
    Springer
    Published 1975
    Staff View
    ISSN:
    1432-1211
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01572278

    Articles: DFG German National Licenses
  12. 12
    Pasquier, L. ; Haimovich, J.
    Springer
    Published 1976
    Staff View
    ISSN:
    1432-1211
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract The maturation of the anti DNP-response in adult and larval amphibians has been compared in two species of anurans,Rana catesbeiana andXenopus laevis. IgM responses were very similar in larvae and adults of both species. Specific IgG antibody synthesis, studied inRana catesbeiana only, was not obvious in larval primary response but was easily detectable in adults. Although metamorphosis results in profound changes in the lymphoid system associated with the apparent acquisition of self tolerance to new antigens, immunological memory of antigens injected during larval life ofRana andXenopus persists after the metamorphosis period.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01576969

    Articles: DFG German National Licenses