Search Results - (Author, Cooperation:L. Muller)
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1E. Sahin ; S. Colla ; M. Liesa ; J. Moslehi ; F. L. Muller ; M. Guo ; M. Cooper ; D. Kotton ; A. J. Fabian ; C. Walkey ; R. S. Maser ; G. Tonon ; F. Foerster ; R. Xiong ; Y. A. Wang ; S. A. Shukla ; M. Jaskelioff ; E. S. Martin ; T. P. Heffernan ; A. Protopopov ; E. Ivanova ; J. E. Mahoney ; M. Kost-Alimova ; S. R. Perry ; R. Bronson ; R. Liao ; R. Mulligan ; O. S. Shirihai ; L. Chin ; R. A. DePinho
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adenosine Triphosphate/biosynthesis ; Aging/metabolism/pathology ; Animals ; Cardiomyopathies/chemically induced/metabolism/pathology/physiopathology ; Cell Proliferation ; DNA, Mitochondrial/analysis ; Doxorubicin/toxicity ; Gluconeogenesis ; Hematopoietic Stem Cells/metabolism/pathology ; Liver/cytology/metabolism ; Mice ; Mitochondria/*metabolism/*pathology ; Myocardium/cytology/metabolism ; RNA/genetics ; Reactive Oxygen Species/metabolism ; Telomerase/deficiency/genetics ; Telomere/enzymology/genetics/*metabolism/*pathology ; Transcription Factors/antagonists & inhibitors/metabolism ; Tumor Suppressor Protein p53/deficiency/genetics/metabolismPublished by: -
2F. L. Muller ; S. Colla ; E. Aquilanti ; V. E. Manzo ; G. Genovese ; J. Lee ; D. Eisenson ; R. Narurkar ; P. Deng ; L. Nezi ; M. A. Lee ; B. Hu ; J. Hu ; E. Sahin ; D. Ong ; E. Fletcher-Sananikone ; D. Ho ; L. Kwong ; C. Brennan ; Y. A. Wang ; L. Chin ; R. A. DePinho
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-08-17Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antineoplastic Agents/pharmacology/therapeutic use ; Biomarkers, Tumor/deficiency/genetics ; Brain Neoplasms/*drug therapy/*genetics/pathology ; Cell Line, Tumor ; Cell Proliferation ; Chromosomes, Human, Pair 1/genetics ; DNA-Binding Proteins/deficiency/genetics ; Enzyme Inhibitors ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Genes, Essential/*genetics ; Genes, Tumor Suppressor ; Glioblastoma/*drug therapy/*genetics/pathology ; Homozygote ; Humans ; Hydroxamic Acids/pharmacology/therapeutic use ; Mice ; Molecular Targeted Therapy/*methods ; Neoplasm Transplantation ; Phosphonoacetic Acid/analogs & derivatives/pharmacology/therapeutic use ; Phosphopyruvate Hydratase/antagonists & inhibitors/deficiency/genetics/metabolism ; RNA, Small Interfering/genetics ; Sequence Deletion/*genetics ; Tumor Suppressor Proteins/deficiency/geneticsPublished by: -
3Dai, X., Wang, H., Zhou, H., Wang, L., Dvořak, J., Bennetzen, J. L., Muller, H.-G.
Genetics Society of America (GSA)
Published 2018Staff ViewPublication Date: 2018-11-07Publisher: Genetics Society of America (GSA)Print ISSN: 0016-6731Topics: BiologyPublished by: -
4M. Schwarzlander ; S. Wagner ; Y. G. Ermakova ; V. V. Belousov ; R. Radi ; J. S. Beckman ; G. R. Buettner ; N. Demaurex ; M. R. Duchen ; H. J. Forman ; M. D. Fricker ; D. Gems ; A. P. Halestrap ; B. Halliwell ; U. Jakob ; I. G. Johnston ; N. S. Jones ; D. C. Logan ; B. Morgan ; F. L. Muller ; D. G. Nicholls ; S. J. Remington ; P. T. Schumacker ; C. C. Winterbourn ; L. J. Sweetlove ; A. J. Meyer ; T. P. Dick ; M. P. Murphy
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-10-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Caenorhabditis elegans/*metabolism ; *Longevity ; Male ; Mitochondria/*metabolism ; Superoxides/*metabolismPublished by: -
5A. J. Westermann ; K. U. Forstner ; F. Amman ; L. Barquist ; Y. Chao ; L. N. Schulte ; L. Muller ; R. Reinhardt ; P. F. Stadler ; J. Vogel
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-01-21Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacterial Proteins/metabolism ; Female ; Gene Expression Regulation/*genetics ; Genes, Bacterial/genetics ; HeLa Cells ; Host-Pathogen Interactions/*genetics ; Humans ; Janus Kinases/metabolism ; Mice ; Microbial Viability/genetics ; RNA, Bacterial/*genetics/metabolism ; RNA, Messenger/genetics/metabolism ; RNA, Untranslated/*genetics/metabolism ; STAT Transcription Factors/metabolism ; Salmonella typhimurium/cytology/*genetics/pathogenicity ; Signal Transduction/genetics ; Transcriptome/genetics ; Virulence/geneticsPublished by: -
6M. Jaskelioff ; F. L. Muller ; J. H. Paik ; E. Thomas ; S. Jiang ; A. C. Adams ; E. Sahin ; M. Kost-Alimova ; A. Protopopov ; J. Cadinanos ; J. W. Horner ; E. Maratos-Flier ; R. A. Depinho
Nature Publishing Group (NPG)
Published 2010Staff ViewPublication Date: 2010-11-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aging/drug effects/*metabolism/*pathology ; Animals ; Avoidance Learning/drug effects ; Brain/anatomy & histology/cytology/drug effects/pathology ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; DNA Damage/drug effects ; Enzyme Activation/drug effects ; Enzyme Reactivators/pharmacology ; Mice ; Mice, Inbred C57BL ; Models, Animal ; Myelin Sheath/metabolism ; Neural Stem Cells/cytology/drug effects/enzymology/pathology ; Organ Size/drug effects ; Phenotype ; Receptors, Estrogen/genetics/metabolism ; Recombinant Fusion Proteins/genetics/metabolism ; Regenerative Medicine ; Smell/drug effects/physiology ; Tamoxifen/analogs & derivatives/pharmacology ; Telomerase/*deficiency/genetics/*metabolism ; Telomere/drug effects/metabolism/pathologyPublished by: -
7Staff View
ISSN: 1432-1246Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
8Saez, L., Legrand, K., Alleyrat, C., Ramisasoa, S., Langlois, J., Muller, L., Omorou, A. Y., De Lavenne, R., Kivits, J., Lecomte, E., Briancon, S., PRALIMAP-INES Trial Group, Böhme, Gailliard, Pourcher, Quinet, Spitz, Toussaint
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-06-23Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Public healthPublished by: -
9Staff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract— Particle-bound hexokinase of rat brain homogenates was solubilized by successive treatment with 0-9 M-NaCl or 003 M-ATP (pH 8.0) and 0-5% (w/v) Triton X-100. This solubilized hexokinase and the soluble hexokinase present in cytoplasm of rat brain homogenates were chromatographed on DEAE-cellulose and some kinetic properties of the isolated hexokinase peaks were studied. The chromatographic separation was greatly influenced by the EDTA-concentration of the buffer used. No significant differences were observed in the chromatographic pattern and in the apparent Km-values for ATP and glucose and the apparent Kt for glucose-6-phosphate (versus ATP) between the soluble and particulate hexokinase solubilized by different reagents. On agarose-electrophoresis the solubilized particulate enzyme migrates as one single band, the soluble hexokinase separates into one major and two minor bands.Type of Medium: Electronic ResourceURL: -
10ORSINI, D. L. M. ; RES, P. C. M. ; LAAR, J. M. ; MULLER, L. M. ; SOPRANO, A. E. L. ; KOOY, Y. M. C. ; TAK, P. P. ; KONING, F.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: It has previously been shown that murine tissue derived T-cells expressing the γδ T-cell receptor can respond to autologous (stressed) cells implying the recognition of an autoantigen. Here we report that a large proportion of human synovial tissue and peripheral blood derived Vδ1+γδ T-cell clones proliferate in response to stimulation with autologous and allogeneic EBV-transformed B-lymphobiastoid cell lines (LCL). In contrast, Vδ1-γ/δ and α/β TCR+ T-cell clones isolated from the same tissue samples did not display proliferation towards the LCL. The proliferative response of these Vδ1+ clones was dependent on contact between responder and stimulator cells and could be blocked by a MoAb to LFA-1 and by antibodies to the γδ TCR/CD3 complex. Because the responses of these clones to LCL cells appear to be independent of the γ-chain co-expressed with the Vδ1-chain these resemble a superantigen response. The capacity of this subset of Vδ1+ T-cell clones to proliferate after stimulation with LCL may imply the recognition of an endogenous epitope. Moreover, since so far we have been able to isolate only LCL reactive γδ T-cell clones from synovial tissue and peripheral blood of reactive arthritis patients and not from peripheral blood of healthy individuals, tbe frequency of such ‘autoreactive’γδ cells may be higher in these patients.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0011-2240Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0005-2736Keywords: (Bilayer vesicle) ; Membrane asymmetry ; Phospholipid packing ; Surface curvature ; ^1H-NMRSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0368-1874Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0368-1874Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0368-1874Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0368-1874Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0368-1874Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0368-1874Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0368-1874Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0368-1874Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: