Search Results - (Author, Cooperation:L. McDaniel)

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  1. 1
    Staff View
    Publication Date:
    2015-05-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; *Disease Progression ; Female ; Male ; Methyl-CpG-Binding Protein 2/*metabolism ; Microglia/*cytology/*physiology ; Rett Syndrome/*pathology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2015-07-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2011-10-21
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    ATP Binding Cassette Transporter 1 ; ATP-Binding Cassette Transporters/metabolism ; Animals ; Cells, Cultured ; *Cercopithecus aethiops/blood/genetics/metabolism ; Cholesterol, LDL/blood ; Gene Expression Regulation/*drug effects ; Gene Silencing ; HEK293 Cells ; Humans ; Lipoproteins, HDL/*blood ; Lipoproteins, VLDL/*blood ; Liver/*drug effects/metabolism ; Male ; MicroRNAs/*antagonists & inhibitors/metabolism ; Oligoribonucleotides, Antisense/*pharmacology ; Time Factors ; Triglycerides/*blood
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    McDaniel, L. ; Houchin, L. A. ; Williamson, S. J. ; Paul, J. H.

    [s.l.] : Nature Publishing Group
    Published 2002
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Viral infection of bacteria can be lytic, causing destruction of the host cell, or lysogenic, in which the viral genome is instead stably maintained as a prophage within its host. Here we show that lysogeny occurs in natural populations of an autotrophic picoplankton (Synechococcus) and that ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/415496a

    Articles: DFG German National Licenses
  5. 5
    MCDANIEL, L. S.

    New Haven, Conn., etc. : Periodicals Archive Online (PAO)
    Published 1932
    Staff View
    ISSN:
    0034-4087
    Topics:
    Theology and Religious Studies
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:3226-1932-027-00-000024

    Articles: DFG German National Licenses
  6. 6
    Mearns, L O ; Giorgi, F ; McDaniel, L ; Shields, C
    Springer
    Published 1995
    Staff View
    ISSN:
    1432-0894
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Geosciences
    Physics
    Notes:
    Abstract Analysis of daily variability of temperature in climate model experiments is important as a model diagnostic and for determination of how such variability may change under perturbed climate conditions. The latter could be important from a climate impacts perspective. We analyze daily mean, diurnal range and variability of surface air temperature in two continuous 3 1/2 year long climate simulations over the continental USA, one for present day conditions and one for conditions under doubled carbon dioxide concentration, conducted with a regional climate model (RegCM), on a 60 km grid, nested in a general circulation model (GCM). Model output is compared with a 30-year daily observational data set for various regions of the USA. In comparison with observations the diurnal range in the model control run is somewhat too low although the daily temperature mean is often well reproduced. The daily variability of temperature is underestimated by the model in all areas, but particularly when and where the observed variability is relatively high. Causes for these underestimations are traced to deficiencies in the general circulation of the driving GCM. With doubled CO2, both maximum and minimum temperatures increase, but the change in the diurnal temperature range (DTR) varies spatially and seasonally. On an annual average over the land domain, the DTR decreases by 0.25'C. Changes in DTR are most strongly correlated with changes in absorbed shortwave radiation at the surface, which explains 72% of the variance in DTR on an annual basis. Change in evaporation was a factor affecting DTR only in the summer when it explained 52% of the variance. The most significant findings with CO2 doubling are substantial decreases in daily variability in winter over large portions of the domain, and localized increases in summer. Causes for these changes are traced to fluctuations in the intensity and position of the jet stream.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00215007

    Articles: DFG German National Licenses
  7. 7
    Mearns LO ; Giorgi, F ; McDaniel, L ; Shields, C
    Springer
    Published 1995
    Staff View
    ISSN:
    1432-0894
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Geosciences
    Physics
    Notes:
    Abstract. Analysis of daily variability of temperature in climate model experiments is important as a model diagnostic and for determination of how such variability may change under perturbed climate conditions. The latter could be important from a climate impacts perspective. We analyze daily mean, diurnal range and variability of surface air temperature in two continuous 3 1/2 year long climate simulations over the continental USA, one for present day conditions and one for conditions under doubled carbon dioxide concentration, conducted with a regional climate model (RegCM), on a 60 km grid, nested in a general circulation model (GCM). Model output is compared with a 30-year daily observational data set for various regions of the USA. In comparison with observations the diurnal range in the model control run is somewhat too low although the daily temperature mean is often well reproduced. The daily variability of temperature is underestimated by the model in all areas, but particularly when and where the observed variability is relatively high. Causes for these underestimations are traced to deficiencies in the general circulation of the driving GCM. With doubled CO2, both maximum and minimum temperatures increase, but the change in the diurnal temperature range (DTR) varies spatially and seasonally. On an annual average over the land domain, the DTR decreases by 0.25°  C. Changes in DTR are most strongly correlated with changes in absorbed shortwave radiation at the surface, which explains 72% of the variance in DTR on an annual basis. Change in evaporation was a factor affecting DTR only in the summer when it explained 52% of the variance. The most significant findings with CO2 doubling are substantial decreases in daily variability in winter over large portions of the domain, and localized increases in summer. Causes for these changes are traced to fluctuations in the intensity and position of the jet stream.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00215007

    Articles: DFG German National Licenses