Search Results - (Author, Cooperation:L. M. Schuchter)
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1C. Twyman-Saint Victor ; A. J. Rech ; A. Maity ; R. Rengan ; K. E. Pauken ; E. Stelekati ; J. L. Benci ; B. Xu ; H. Dada ; P. M. Odorizzi ; R. S. Herati ; K. D. Mansfield ; D. Patsch ; R. K. Amaravadi ; L. M. Schuchter ; H. Ishwaran ; R. Mick ; D. A. Pryma ; X. Xu ; M. D. Feldman ; T. C. Gangadhar ; S. M. Hahn ; E. J. Wherry ; R. H. Vonderheide ; A. J. Minn
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-03-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antigens, CD274/*antagonists & inhibitors/metabolism ; CTLA-4 Antigen/*antagonists & inhibitors ; Cell Cycle Checkpoints/*drug effects ; Female ; Humans ; Melanoma/*drug therapy/*immunology/pathology/*radiotherapy ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Receptors, Antigen, T-Cell/drug effects/immunology/metabolism ; T-Lymphocytes/cytology/*drug effects/immunology/*radiation effects ; T-Lymphocytes, Regulatory/drug effects/immunology/radiation effectsPublished by: -
2Yam, C., Xu, X., Davies, M. A., Gimotty, P. A., Morrissette, J. J. D., Tetzlaff, M. T., Wani, K. M., Liu, S., Deng, W., Buckley, M., Zhao, J., Amaravadi, R. K., Haas, N. B., Kudchadkar, R. R., Pavlick, A. C., Sosman, J. A., Tawbi, H., Walker, L., Schuchter, L. M., Karakousis, G. C., Gangadhar, T. C.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-01-04Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
3Zhang, G., Wu, L. W., Mender, I., Barzily-Rokni, M., Hammond, M. R., Ope, O., Cheng, C., Vasilopoulos, T., Randell, S., Sadek, N., Beroard, A., Xiao, M., Tian, T., Tan, J., Saeed, U., Sugarman, E., Krepler, C., Brafford, P., Sproesser, K., Murugan, S., Somasundaram, R., Garman, B., Wubbenhorst, B., Woo, J., Yin, X., Liu, Q., Frederick, D. T., Miao, B., Xu, W., Karakousis, G. C., Xu, X., Schuchter, L. M., Mitchell, T. C., Kwong, L. N., Amaravadi, R. K., Lu, Y., Boland, G. M., Wei, Z., Nathanson, K., Herbig, U., Mills, G. B., Flaherty, K. T., Herlyn, M., Shay, J. W.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-10-02Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
4Moore, H. C. F. ; Mick, R. ; Solin, L. J. ; Sickles, C. ; Mangan, P. A. ; Luger, S. M. ; Fox, K. R. ; Schuchter, L. M. ; Loh, E. ; Porter, D. L. ; Schuster, S. ; Buzby, G. P. ; Glatstein, E. ; Silberstein, L. E. ; Stadtmauer, E. A.
Springer
Published 1999Staff ViewISSN: 1569-8041Keywords: breast cancer ; local regional therapy ; stem-cell transplantationSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Background: High-dose chemotherapy with autologous stem-cell transplantation is used increasingly in the treatment of poor-prognosis primary breast cancer. Because these patients may be cured with standard multimodality therapy, it is important to address both the efficacy of transplantation, and its effect on the delivery of standard treatments including local radiation therapy. Patients and methods: Patients with high risk primary breast cancer were treated with high-dose cyclophosphamide and thiotepa and stem-cell transplant following surgery and conventional-dose adjuvant chemotherapy. Outcome, including sites of failure and delivery of local radiation therapy, was assessed for 103 patients. Results: Overall and disease-free survival rates at 18 months were 83% (± 4%) and 77% (± 4%) respectively. Twenty patients (19.4%) received radiation therapy prior to transplant. Of the remaining 83, 77 received radiation therapy after transplant. Overall, 5 (19.2%) of 26 first sites of recurrence were local alone. For patients receiving radiation prior to transplant, 3 of 7 (43%, 95% CI: 6%–80%) sites of first recurrence were local, while 2 of 19 (10.5%, 95% CI: 0%–24.5%) sites of first recurrence were local alone in patients receiving post-transplant radiation or no radiation. Conclusion: Transplantation does not appear to significantly compromise the delivery or outcome of local radiation therapy for primary breast cancer.Type of Medium: Electronic ResourceURL: