Search Results - (Author, Cooperation:L. Johnstone)

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  1. 1
    Staff View
    Publication Date:
    2018-06-20
    Publisher:
    Cold Spring Harbor Laboratory Press
    Print ISSN:
    0890-9369
    Topics:
    Biology
    Published by:
    http://www.cshlpress.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    J. Prado-Martinez ; P. H. Sudmant ; J. M. Kidd ; H. Li ; J. L. Kelley ; B. Lorente-Galdos ; K. R. Veeramah ; A. E. Woerner ; T. D. O'Connor ; G. Santpere ; A. Cagan ; C. Theunert ; F. Casals ; H. Laayouni ; K. Munch ; A. Hobolth ; A. E. Halager ; M. Malig ; J. Hernandez-Rodriguez ; I. Hernando-Herraez ; K. Prufer ; M. Pybus ; L. Johnstone ; M. Lachmann ; C. Alkan ; D. Twigg ; N. Petit ; C. Baker ; F. Hormozdiari ; M. Fernandez-Callejo ; M. Dabad ; M. L. Wilson ; L. Stevison ; C. Camprubi ; T. Carvalho ; A. Ruiz-Herrera ; L. Vives ; M. Mele ; T. Abello ; I. Kondova ; R. E. Bontrop ; A. Pusey ; F. Lankester ; J. A. Kiyang ; R. A. Bergl ; E. Lonsdorf ; S. Myers ; M. Ventura ; P. Gagneux ; D. Comas ; H. Siegismund ; J. Blanc ; L. Agueda-Calpena ; M. Gut ; L. Fulton ; S. A. Tishkoff ; J. C. Mullikin ; R. K. Wilson ; I. G. Gut ; M. K. Gonder ; O. A. Ryder ; B. H. Hahn ; A. Navarro ; J. M. Akey ; J. Bertranpetit ; D. Reich ; T. Mailund ; M. H. Schierup ; C. Hvilsom ; A. M. Andres ; J. D. Wall ; C. D. Bustamante ; M. F. Hammer ; E. E. Eichler ; T. Marques-Bonet
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-07-05
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Africa ; Animals ; Animals, Wild/genetics ; Animals, Zoo/genetics ; Asia, Southeastern ; Evolution, Molecular ; Gene Flow/genetics ; *Genetic Variation ; Genetics, Population ; Genome/genetics ; Gorilla gorilla/classification/genetics ; Hominidae/classification/*genetics ; Humans ; Inbreeding ; Pan paniscus/classification/genetics ; Pan troglodytes/classification/genetics ; Phylogeny ; Polymorphism, Single Nucleotide/genetics ; Population Density
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-08-29
    Publisher:
    National Academy of Sciences
    Print ISSN:
    0027-8424
    Electronic ISSN:
    1091-6490
    Topics:
    Biology
    Medicine
    Natural Sciences in General
    Published by:
    http://www.nasonline.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Johnstone, L. E. ; Leng, G. ; Brown, C. H.

    Oxford, UK : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1365-2826
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Neurotensin increases the firing rate of supraoptic nucleus oxytocin and vasopressin neurones in vitro and induces Fos protein expression in the supraoptic nucleus in vivo. Here, we used extracellular single-unit electrophysiological recording combined with local microdialysis administration of neurotensin (1 mM at 2 µl/min) to investigate the effects of locally applied neurotensin on the firing of oxytocin and vasopressin neurones in urethane-anaesthetized virgin and lactating rats. Neurotensin decreased the mean firing rate of oxytocin cells in virgin, but not lactating, rats. In addition, neurotensin increased the index of dispersion (a measure of the variability of firing) in virgin, but not lactating, rats. By contrast to oxytocin cells, neurotensin increased the mean firing rate of vasopressin cells in both virgin and lactating rats, but did not alter the index of dispersion. The increase in firing of phasic vasopressin cells was achieved through an increase in intraburst frequency (rather than an increase in burst duration or decrease in interburst interval), which resulted from a reduction of the spike-frequency adaptation that develops over the course of phasic bursts. Thus, neurotensin has differential effects on activity patterning in oxytocin and vasopressin cells and the effects on oxytocin cells, but not vasopressin cells, depend upon the physiological status of the animal. The increase in the variability of firing of oxytocin cells induced by neurotensin in virgin rats, but not in lactating rats, suggests that neurotensin (or other neurotransmitters/neuromodulators with similar actions) might establish conditions that predispose oxytocin cells to fire in milk-ejection bursts in lactating rats.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2826.2004.01208.x

    Articles: DFG German National Licenses
  5. 5
    Otukonyong, E. E. ; Okere, C. O. ; Johnstone, L. E. ; Murata, T. ; Kaba, H. ; Higuchi, T.

    Oxford, UK : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1365-2826
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    This study examined the effect of suckling on nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d, a histochemical marker for nitric oxide synthase, NOS) reactivity and neuronal NOS mRNA expression in the paraventricular (PVN) and supraoptic (SON) nuclei of lactating rats. Freely nursing (non-separated) dams and those separated from pups for 12 h and then reunited for 0, 15, 30, 60, 90, 120 and 180 min were used for the study. Dams separated from pups and sacrificed at time zero (without reunion) showed a significant decrease in NADPH-d staining and NADPH-d positive cells as well as in the NOS mRNA expression in the PVN and SON compared to that observed in non-separated dams. Reunion with pups and restoration of suckling significantly increased NADPH-d reactivity after 15, 30, 60 min, but not after 90, 120 and 180 min compared to non-reunited pups-deprived dams. A pattern of NADPH-d reactivity and neuronal NOS mRNA expression indistinguishable from that observed during free lactation was reinstated shortly (15 min) after the restoration of suckling stimulus, suggesting that the NADPH-d reactivity in lactation depends on the presence of the suckling stimulus. These results show that suckling stimulus may play a modulatory role in the regulation of NOS reactivity in the magnocellular neurones of the hypothalamic PVN and SON during lactation.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2826.2000.00548.x

    Articles: DFG German National Licenses
  6. 6
    Craig Johnstone, L.

    New York : Periodicals Archive Online (PAO)
    Published 1971
    Staff View
    ISSN:
    0015-7120
    Topics:
    Political Science
    Law
    URL:
    http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:1086-1971-049-04-000010

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    1432-198X
    Keywords:
    Key words: Bartter’s syndrome
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract. A male infant is described who had polyuria over the 4 months of his life with urine volumes exceeding 1,000 ml/kg per day, severe serum electrolyte losses, metabolic alkalosis and increased plasma renin activity (56 ng/ml per hour). He had a normal blood pressure and glomerular filtration rate when fluid replete. The urine flow rate was about 25% of the glomerular filtration rate. Renal histology showed hyperplasia of the juxtaglomerular apparatus and abnormalities of the proximal tubules. The features of this case suggest an extreme form of Bartter’s syndrome presenting from the first days of life.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004670050147

    Articles: DFG German National Licenses