Search Results - (Author, Cooperation:L. J. Whalley)
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1I. J. Deary ; J. Yang ; G. Davies ; S. E. Harris ; A. Tenesa ; D. Liewald ; M. Luciano ; L. M. Lopez ; A. J. Gow ; J. Corley ; P. Redmond ; H. C. Fox ; S. J. Rowe ; P. Haggarty ; G. McNeill ; M. E. Goddard ; D. J. Porteous ; L. J. Whalley ; J. M. Starr ; P. M. Visscher
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-01-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aged ; Aging/*genetics/physiology/*psychology ; Child ; Cognition/physiology ; Gene-Environment Interaction ; Genetic Association Studies ; Genome, Human/genetics ; Genotype ; Humans ; Intelligence/*genetics/*physiology ; Intelligence Tests ; Models, Genetic ; Phenotype ; Polymorphism, Single Nucleotide/*geneticsPublished by: -
2Whalley, L. J. ; Robinson, T. J. ; Mcisaac, Mary ; Wolff, Sula
Oxford, UK : Blackwell Publishing Ltd
Published 1978Staff ViewISSN: 1469-7610Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyNotes: Children referred for psychiatric reports by the Scottish Children's Hearings were compared with other children known to the Reporter and with antisocial children referred to psychiatrists from other sources. The first group of children were characterized by the severity of their symptoms and family disturbance. They differed from other conduct disordered children referred to psychiatrists in being older, containing a greater excess of boys and, in the case of boys, more often coming from disrupted families with substitute fathers rather than single mothers. Associated features were very high rates of itinerant employment, criminality, excessive drinking and psychiatric pathology among the father figures and very large sibships, especially among the girls.Type of Medium: Electronic ResourceURL: -
3Staff View
ISSN: 1432-1041Keywords: Rolipram ; amitriptyline ; depression ; adverse effects ; efficacySource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyMedicineNotes: Summary The antidepressant efficacy and adverse-effects of rolipram (a dialkoxyphenyl-2-pyrrolidone) were compared to those of amitriptyline in the treatment of depressive illness requiring hospital admission in a double-blind study. Fifty patients meeting DSM-III criteria for Major Depression whose scores on the Hamilton Rating Scale for Depression (HRSD) remained above 17 after 5 to 7 days on placebo were randomly allocated to either treatment. The rate of recovery in those patients treated by amitriptyline was substantially greater than in those patients treated by rolipram. Twice as many patients dropped out of treatment by rolipram because of lack of efficacy or adverse-effects compared with patients treated by amitriptyline. Rolipram produced fewer adverse-effects attributable to cholinergic blockade, but more nausea. We conclude that amitriptyline is more effective than rolipram in the treatment of depressed hospital in-patients.Type of Medium: Electronic ResourceURL: