Search Results - (Author, Cooperation:L. H. Tsai)
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1C. Y. Chung ; V. Khurana ; P. K. Auluck ; D. F. Tardiff ; J. R. Mazzulli ; F. Soldner ; V. Baru ; Y. Lou ; Y. Freyzon ; S. Cho ; A. E. Mungenast ; J. Muffat ; M. Mitalipova ; M. D. Pluth ; N. T. Jui ; B. Schule ; S. J. Lippard ; L. H. Tsai ; D. Krainc ; S. L. Buchwald ; R. Jaenisch ; S. Lindquist
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-10-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Benzimidazoles/chemistry/*pharmacology ; Endoplasmic Reticulum Stress/drug effects ; Female ; Humans ; Induced Pluripotent Stem Cells/cytology/metabolism ; Mutation ; Neurogenesis ; Neurons/*drug effects/metabolism/pathology ; Parkinson Disease/genetics/*metabolism ; Rats ; alpha-Synuclein/genetics/*metabolismPublished by: -
2J. Graff ; D. Rei ; J. S. Guan ; W. Y. Wang ; J. Seo ; K. M. Hennig ; T. J. Nieland ; D. M. Fass ; P. F. Kao ; M. Kahn ; S. C. Su ; A. Samiei ; N. Joseph ; S. J. Haggarty ; I. Delalle ; L. H. Tsai
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-06Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acetylation/drug effects ; Alzheimer Disease/complications/genetics/physiopathology ; Amyloid beta-Peptides/toxicity ; Animals ; Brain/drug effects/metabolism/*physiopathology ; Disease Models, Animal ; *Epigenesis, Genetic/drug effects ; Gene Expression Regulation/drug effects ; Gene Knockdown Techniques ; Hippocampus/drug effects/metabolism ; Histone Deacetylase 2/deficiency/*genetics/metabolism ; Histones/metabolism ; Humans ; Hydrogen Peroxide/toxicity ; Memory Disorders/complications/*genetics/*physiopathology ; Mice ; Neurodegenerative Diseases/complications/*genetics/*physiopathology ; Neuronal Plasticity/drug effects/genetics ; Peptide Fragments/toxicity ; Phosphorylation/drug effects ; Promoter Regions, Genetic/drug effects/genetics ; RNA Polymerase II/metabolism ; Receptors, Glucocorticoid/metabolismPublished by: -
3Staff View
Publication Date: 2014-03-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aging/*metabolism ; Alzheimer Disease/*metabolism ; Animals ; Humans ; *Oxidative Stress ; Repressor Proteins/*metabolismPublished by: -
4E. Gjoneska ; A. R. Pfenning ; H. Mathys ; G. Quon ; A. Kundaje ; L. H. Tsai ; M. Kellis
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-02-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alzheimer Disease/*genetics/*immunology/physiopathology ; Animals ; Chromatin/genetics/metabolism ; Conserved Sequence ; Disease Models, Animal ; Down-Regulation/genetics ; Enhancer Elements, Genetic/genetics ; Epigenesis, Genetic/*genetics ; Epigenomics ; Female ; Genetic Predisposition to Disease/genetics ; Genome-Wide Association Study ; Hippocampus/metabolism ; Humans ; Immunity/genetics ; Memory/physiology ; Mice ; *Models, Biological ; Neuronal Plasticity/genetics ; Polymorphism, Single Nucleotide/genetics ; Proto-Oncogene Proteins/metabolism ; Trans-Activators/metabolism ; Transcription, Genetic/genetics ; Up-Regulation/geneticsPublished by: -
5A. Kundaje ; W. Meuleman ; J. Ernst ; M. Bilenky ; A. Yen ; A. Heravi-Moussavi ; P. Kheradpour ; Z. Zhang ; J. Wang ; M. J. Ziller ; V. Amin ; J. W. Whitaker ; M. D. Schultz ; L. D. Ward ; A. Sarkar ; G. Quon ; R. S. Sandstrom ; M. L. Eaton ; Y. C. Wu ; A. R. Pfenning ; X. Wang ; M. Claussnitzer ; Y. Liu ; C. Coarfa ; R. A. Harris ; N. Shoresh ; C. B. Epstein ; E. Gjoneska ; D. Leung ; W. Xie ; R. D. Hawkins ; R. Lister ; C. Hong ; P. Gascard ; A. J. Mungall ; R. Moore ; E. Chuah ; A. Tam ; T. K. Canfield ; R. S. Hansen ; R. Kaul ; P. J. Sabo ; M. S. Bansal ; A. Carles ; J. R. Dixon ; K. H. Farh ; S. Feizi ; R. Karlic ; A. R. Kim ; A. Kulkarni ; D. Li ; R. Lowdon ; G. Elliott ; T. R. Mercer ; S. J. Neph ; V. Onuchic ; P. Polak ; N. Rajagopal ; P. Ray ; R. C. Sallari ; K. T. Siebenthall ; N. A. Sinnott-Armstrong ; M. Stevens ; R. E. Thurman ; J. Wu ; B. Zhang ; X. Zhou ; A. E. Beaudet ; L. A. Boyer ; P. L. De Jager ; P. J. Farnham ; S. J. Fisher ; D. Haussler ; S. J. Jones ; W. Li ; M. A. Marra ; M. T. McManus ; S. Sunyaev ; J. A. Thomson ; T. D. Tlsty ; L. H. Tsai ; W. Wang ; R. A. Waterland ; M. Q. Zhang ; L. H. Chadwick ; B. E. Bernstein ; J. F. Costello ; J. R. Ecker ; M. Hirst ; A. Meissner ; A. Milosavljevic ; B. Ren ; J. A. Stamatoyannopoulos ; T. Wang ; M. Kellis
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-02-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Base Sequence ; Cell Lineage/genetics ; Cells, Cultured ; Chromatin/chemistry/genetics/metabolism ; Chromosomes, Human/chemistry/genetics/metabolism ; DNA/chemistry/genetics/metabolism ; DNA Methylation ; Datasets as Topic ; Enhancer Elements, Genetic/genetics ; Epigenesis, Genetic/*genetics ; *Epigenomics ; Genetic Variation/genetics ; Genome, Human/*genetics ; Genome-Wide Association Study ; Histones/metabolism ; Humans ; Organ Specificity/genetics ; RNA/genetics ; Reference ValuesPublished by: -
6Staff View
Publication Date: 2011-01-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cognition/drug effects/*physiology ; Gene Expression Regulation/drug effects ; Hippocampus/drug effects ; Humans ; Insulin-Like Growth Factor II/metabolism/pharmacology ; Memory/drug effects/*physiology ; Oligonucleotides, Antisense/pharmacology ; RatsPublished by: -
7Patrick, G. N. ; Zukerberg, L. ; Nikolic, M. ; de la Monte, S. ; Dikkes, P. ; Tsai, L.-H.
[s.l.] : Nature Publishing Group
Published 2001Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Patrick et al. reply Yoo and Lubec show that the amount of p25 is decreased in the brains they studied from patients with Alzheimer's disease or Down's syndrome. Their results persuaded us to conduct a more extensive survey of the p25/p35 ratio in AD brains (to be ...Type of Medium: Electronic ResourceURL: