Search Results - (Author, Cooperation:L. Godfrey)
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1Latest Papers from Table of Contents or Articles in PressR. Soria ; K. S. Long ; W. P. Blair ; L. Godfrey ; K. D. Kuntz ; E. Lenc ; C. Stockdale ; P. F. Winkler
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-03-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-02-09Publisher: American Heart Association (AHA)Print ISSN: 0009-7330Electronic ISSN: 1524-4571Topics: MedicineKeywords: Contractile Function, Stem Cells, Congenital Heart Disease, Echocardiography, ImagingPublished by: -
3Latest Papers from Table of Contents or Articles in PressHansford, J., Wright, P. C., Rasoamiaramanana, A., Perez, V. R., Godfrey, L. R., Errickson, D., Thompson, T., Turvey, S. T.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-09-13Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
4Articles: DFG German National LicensesGodfrey, L. ; Philip, J. ; Sebastian, M. T.
[S.l.] : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: All the nine elastic constants of the orthorhombic crystal lithium hydrazinium sulfate, Li(N2H5)SO4, have been determined by measuring ultrasonic velocities using pulse echo overlap technique at 10 MHz. Temperature variation of all the six diagonal elastic constants and the three off-diagonal combinations have been measured between 300 and 450 K. Some of the constants show anomalous behavior in the 410–440 K temperature region, which is attributed to a phase transition in the crystal near 425 K. Magnitude of the velocity anomaly is comparatively small. A new high-temperature ultrasonic bond material suitable for transverse waves is also reported.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 0168-583XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0008-8080Topics: HistoryTheology and Religious StudiesNotes: BOOK REVIEWSURL: -
8Articles: DFG German National LicensesRoney, J.M. ; Armitage, J.C. ; Carnegie, R.K. ; Giles, G.L. ; Hemingway, R.J. ; McPherson, A.C. ; Pinfold, J.L. ; Waterhouse, J. ; Carter, A.A. ; Hargrove, C.K. ; Hill, J.C. ; Carter, J.R. ; Godfrey, L. ; Elcombe, P.A. ; Lloyd, S.L. ; Pritchard, T.W.
Amsterdam : ElsevierStaff ViewISSN: 0168-9002Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesMes, H. ; Dixit, M.S. ; Godfrey, L. ; Hanna, D. ; Hargrove, C.K. ; Losty, M.J. ; Oakham, F.G. ; Carnegie, R.K. ; McPherson, A.C. ; Lorazo, B. ; Bavaria, G. ; Jeremie, H. ; Martin, J.-P. ; Dumont, J.J. ; Lessard, L. ; Payne, R. ; Hemingway, R.J.
Amsterdam : ElsevierStaff ViewISSN: 0168-9002Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesAdams, M.R. ; Engelmann, R. ; Grannis, P.D. ; Horstkotte, J. ; Godfrey, L. ; Linn, S.L. ; Marx, M.D. ; Timms, J. ; Cutts, D. ; Callas, J. ; Willins, J. ; Ahrens, L. ; Franzini, P. ; Yamin, P. ; Tuts, P.M. ; Levy, P.W. ; Aronson, S. ; Youssef, S.
Amsterdam : ElsevierStaff ViewISSN: 0168-9002Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1573-2657Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary The relationship between calcium concentration ([Ca2+]) and force in smooth muscle can be studied by permeabilizing the sarcolemma and bathing the preparation in a mock intracellular solution. Normally [Ca2+] is set in these solutions using the Ca2+ chelator EGTA in the concentration range of 4–10 mm. This study shows that lowering total EGTA concentration ([EGTA]t) below 10 mm depresses Ca2+-activated force generated in 0.1 μm Ca2+. The observed threshold for the effect of EGTAt is 0.2 mm, and the effect is maximal at approximately 10 mm. BAPTA, another Ca2+ chelator, also produces this effect. Tension production in smooth muscle is controlled by acto-myosin interaction. This in turn is mediated by the relative activities of myosin light chain kinase (MLCK) and phosphatase (MLCP). Inhibiting MLCP with Microcystin LR (10 μm), an increase [EGTAt] from 0.2 mm to 10 mm still enhanced force. This suggests that EGTA promotes phosphorylation of myosin by the activation of MLCK and not by inhibition of MLCP.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1573-2657Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary Tension responses of rat ventricular trabeculae subjected to successive ‘treatment’ with EGTA and Triton X-100 are described in order to investigate the effects of chemical ‘skinning’ techniques. In some preparations the alkaloid saponin was also used before Triton. Ultrastructural evidence is cited that the ‘EGTA-treatment’ fails to render cells ‘hyperpermeable’, i.e. freely permeable to small ions, whereas both saponin and Triton do so. In this paper we show that contractile responses like those described previously for the ‘EGTA-treated’ tissue can be obtained. However, more detailed examination shows that such behaviour is quantitatively distinct from that of conventionally skinned fibres in a way that is incompatible with the notion of ‘hyperpermeability’. The Ca-sensitivity after treatment with either EGTA, saponin or Triton is identical in our hands. However, this is not explained by free access of Ca (and EGTA) to the intracellular space in the EGTA-treated preparation: contractures develop with very different time courses, being fastest after Triton and only marginally slower when first exposed to saponin but a factor of five times slower after ‘EGTA-treatment’ alone. This applies to contractures evoked direct from Ca2+ concentration ⋍ 10−9 m to the test Ca2+ concentration at constant total buffer concentration. ‘EGTA-treated’ fibres develop tension when ATP or creatine phosphate (CrP) are removed from the bath. However, responses to ADP and to CrP changes persist with millimolar levels of ATP present, quite unlike the Triton-skinned muscle. Exposure to each of a variety of solutions for 24h produce preparations showing similar behaviour: whatever the explanation for the EGTA-‘skinning’ phenomenon it is not dependent upon low bathing Ca2+ concentration. On the basis of the functional characteristics described here, and the structural results cited, we conclude that the cell membrane continues to function as a selective permeability barrier after ‘EGTA-treatment’: this treatment does not produce a model of a selectively ‘skinned’ cardiac cell.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0044-8249Keywords: Chemistry ; General ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: Infolge seiner eigenartigen Struktur kann Aminoguanidin als Hydrazin-, Guanidin- oder Formamidin-Derivat reagieren. Durch vielfältige Additions- und Kondensationsreaktionen entstehen Produkte, die sich zu heterocyclischen Verbindungen umsetzen lassen. In vielen Fällen erhält man die Heterocyclen in einer Stufe direkt aus Aminoguanidin.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0570-0833Keywords: Aminoguanidine ; Heterocycles ; Chemistry ; General ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: Due to its unique structure, aminoguanidine is capable of reacting as a derivative of hydrazine, guanidine or formamidine. Addition and condensation reactions yield products which can be cyclized to heterocyclic compounds. Frequently, heterocyclics are directly accessible from aminoguanidine in one stage.Type of Medium: Electronic ResourceURL: