Search Results - (Author, Cooperation:L. Excoffier)
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1C. Moreau ; C. Bherer ; H. Vezina ; M. Jomphe ; D. Labuda ; L. Excoffier
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-11-05Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Demography ; Emigration and Immigration ; Family Characteristics ; Female ; Fertility ; *Gene Pool ; Genes ; *Genetic Fitness ; Humans ; Male ; Marriage ; *Pedigree ; *Population Dynamics ; Quebec ; Registries ; Reproduction ; *Selection, GeneticPublished by: -
2D. Reich ; N. Patterson ; D. Campbell ; A. Tandon ; S. Mazieres ; N. Ray ; M. V. Parra ; W. Rojas ; C. Duque ; N. Mesa ; L. F. Garcia ; O. Triana ; S. Blair ; A. Maestre ; J. C. Dib ; C. M. Bravi ; G. Bailliet ; D. Corach ; T. Hunemeier ; M. C. Bortolini ; F. M. Salzano ; M. L. Petzl-Erler ; V. Acuna-Alonzo ; C. Aguilar-Salinas ; S. Canizales-Quinteros ; T. Tusie-Luna ; L. Riba ; M. Rodriguez-Cruz ; M. Lopez-Alarcon ; R. Coral-Vazquez ; T. Canto-Cetina ; I. Silva-Zolezzi ; J. C. Fernandez-Lopez ; A. V. Contreras ; G. Jimenez-Sanchez ; M. J. Gomez-Vazquez ; J. Molina ; A. Carracedo ; A. Salas ; C. Gallo ; G. Poletti ; D. B. Witonsky ; G. Alkorta-Aranburu ; R. I. Sukernik ; L. Osipova ; S. A. Fedorova ; R. Vasquez ; M. Villena ; C. Moreau ; R. Barrantes ; D. Pauls ; L. Excoffier ; G. Bedoya ; F. Rothhammer ; J. M. Dugoujon ; G. Larrouy ; W. Klitz ; D. Labuda ; J. Kidd ; K. Kidd ; A. Di Rienzo ; N. B. Freimer ; A. L. Price ; A. Ruiz-Linares
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-07-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Americas ; Asia ; Cluster Analysis ; Emigration and Immigration/*history/statistics & numerical data ; Gene Flow ; Genetics, Population ; History, Ancient ; Humans ; Indians, North American/*genetics/*history ; Models, Genetic ; *Phylogeny ; Polymorphism, Single Nucleotide/genetics ; SiberiaPublished by: -
3Peischl, S., Dupanloup, I., Foucal, A., Jomphe, M., Bruat, V., Grenier, J.-C., Gouy, A., Gilbert, K. J., Gbeha, E., Bosshard, L., Hip-Ki, E., Agbessi, M., Hodgkinson, A., Vezina, H., Awadalla, P., Excoffier, L.
Genetics Society of America (GSA)
Published 2018Staff ViewPublication Date: 2018-01-30Publisher: Genetics Society of America (GSA)Print ISSN: 0016-6731Topics: BiologyPublished by: -
4Popadin, K., Peischl, S., Garieri, M., Sailani, M. R., Letourneau, A., Santoni, F., Lukowski, S. W., Bazykin, G. A., Nikolaev, S., Meyer, D., Excoffier, L., Reymond, A., Antonarakis, S. E.
Cold Spring Harbor Laboratory Press
Published 2018Staff ViewPublication Date: 2018-01-03Publisher: Cold Spring Harbor Laboratory PressElectronic ISSN: 1549-5469Topics: BiologyMedicinePublished by: -
5Nicod, J.-C. ; Wang, Y. Z. ; Excoffier, L. ; Largiadèr, C. R.
Oxford, UK; Malden, USA : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Low levels of mitochondrial DNA variation were observed among pike Esox lucius populations from major drainage systems of Europe. Populations from the Italian peninsula including southern Switzerland were genetically distinct from other samples.Type of Medium: Electronic ResourceURL: -
6Grundschober, C. ; Sanchez-Mazas, A. ; Excoffier, L. ; Langaney, A. ; Jeannet, M. ; Tiercy, J.-M.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1744-313XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: Allelic diversity at the HLA-DPB1 locus was determined by PCR-oligotyping in a sample of 125 healthy Swiss individuals. A total of 17 alleles were detected among which four main alleles (DPB 1*0401, *0201, *0301, *0402) reached a cumulative frequency of 74.8%. HLA-A and -B (by serology) and HLA-DRB1 (by oligotyping) allelic polymorphisms were analysed also. HLA-B and HLA-DRB1 loci were highly polymorphic with 25 and 28 alleles respectively and similar heterozygosity levels of 0.93 and 0.92. These two loci were found to be more polymorphic than expected under neutrality, while lower heterozygosity levels were found for HLA-A (0.87) and DPB1 (0.81) loci. This paper presents also a global comparison of DPB1 allelic frequencies among 15 populations from four continents. As opposed to the DRB1 locus, overall DPB1 is shown to have a lower level of polymorphism and may be considered as neutral in all tested populations. DPB 1 genetic diversity is correlated significantly with geography also, as found previously for DRB1. Two- and four-locus haplotype frequencies were determined and the significance of their linkage disequilibrium tested by an original non-parametric method. A significant positive linkage disequilibrium was found for 11 A-B, 16 B-DRB1, 7 DRB1-DPB1 and 3 A-B-DRB1-DPB1 haplotypes. The overall linkage disequilibrium between DRB1 and DPB1 was much lower than expected from the physical distance and lower than for A-B and B-DRB1 pairs. The implications of these results for bone marrow transplantation and for the evolution of HLA loci are discussed.Type of Medium: Electronic ResourceURL: -
7Flint, J. ; Bond, J. ; Rees, D. C. ; Boyce, A. J. ; Roberts-Thomson, J. M. ; Excoffier, L. ; Clegg, J. B. ; Beaumont, M. A. ; Nichols, R. A. ; Harding, R. M.
Springer
Published 1999Staff ViewISSN: 1432-1203Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract. We have used a new method for binning minisatellite alleles (semi-automated allele aggregation) and report the extent of population diversity detectable by eleven minisatellite loci in 2689 individuals from 19 human populations distributed widely throughout the world. Whereas population relationships are consistent with those found in other studies, our estimate of genetic differentiation (Fst) between populations is less than 8%, which is lower than comparative estimates of between 10%–15% obtained by using other sources of polymorphism data. We infer that mutational processes are involved in reducing Fst estimates from minisatellite data because, first, the lowest Fst estimates are found at loci showing autocorrelated frequencies among alleles of similar size and, second, Fst declines with heterozygosity but by more than predicted assuming simple models of mutation. These conclusions are consistent with the view that minisatellites are subject to selective or mutational constraints in addition to those expected under simple stepwise mutation models.Type of Medium: Electronic ResourceURL: