Search Results - (Author, Cooperation:L. Engstrand)

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  1. 1
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2016-01-09
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Asia ; Chromosome Mapping ; DNA, Bacterial/genetics/isolation & purification ; Europe ; Genome, Bacterial/*genetics ; Helicobacter Infections/*microbiology ; Helicobacter pylori/*genetics/isolation & purification ; Human Migration ; Humans ; *Hybridization, Genetic ; Ice Cover/microbiology ; Mummies/microbiology ; Phylogeny ; Phylogeography ; Sequence Analysis, DNA ; Stomach/*microbiology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
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    SELLSTEDT, H. ; ENGSTRAND, L. ; GEJVALL, N.-G.

    [s.l.] : Nature Publishing Group
    Published 1966
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] THE main drawback to the use of radiocarbon dating in archaeology, ethnology and similar fields has been the difficulty with which the necessary carbon dioxide is obtained from the available remains. Delicate implements, such as tools and wooden musical instruments, or a few remnants of charred and ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    SCHEYNIUS, A. ; ENGSTRAND, L.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1991
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Induced expression of the intercellular adhesion molecule 1 (ICAM-1) and of the major histocompatibility complex (MHC) class II antigens has been simultaneously observed on keratinocytes and epithelial ceils in the thyroid and kidney, suggesting that ICAM-i and HLA-DR expression might be under common regulation. We have previously found an association between the presence of Helicohacter pylori and an induced expression of class II antigens on gastric epithelial toils in gastric biopsy specimens from patients with gastritis. In this study we investigated whether ICAM-l could also be expressed on the gastric epithelium. Thirty-one patients with clinical indications for upper gastrointestinal endoscopy were examined. In 23 patients gastritis was diagnosed endoscopically and histologically and H. pylori was cultured from biopsy specimens. In eight patients neither histological gastritis nor growth of the bacteria was observed. Immunoperoxidase staining demonstrated expression of HLA-DR but not ICAM-I on the gastric epithelial cells in all patients with H. pylori-associated gastritis, indicating regulatory mechanisms different from those of other epithelial cells.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Engstrand, L.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1574-695X
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    Abstract Presence of Helicobacter pylori in the human gastric mucosa is associated with chronic gastritis and promotes the formation of peptic ulceration. Furthermore, long-term gastritis caused by the bacteria represents an increased risk of developing gastric cancer. Much controversy remains about the pathogenic mechanisms by which H. pylori can induce disease because of the limitations of animal models and the relevance of in vitro observations to the in vivo disease process. Studies of putative pathogenic factors such as induction of inflammatory mediators and immune evasion are required to understand how to design a vaccine against the infection. Vaccine adjuvants, delivery systems and therapeutic vaccination are likely to be the areas of major progress in the future. Data related to immunological aspects and vaccine development in potential animal models are reviewed.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses