Search Results - (Author, Cooperation:L. Boon)

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  1. 1
    Staff View
    Publication Date:
    2014-06-17
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Bacterial Infections/immunology/metabolism ; Disease Resistance/drug effects/*genetics/*immunology ; Endotoxemia/genetics/immunology/metabolism ; Enzyme Activation/drug effects ; Gene Expression Regulation/drug effects ; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism ; Inflammation/enzymology/genetics/metabolism ; Kynurenine/metabolism ; Lipopolysaccharides/pharmacology ; Mice ; Phosphorylation ; Receptors, Aryl Hydrocarbon/genetics/*metabolism ; Signal Transduction ; Tryptophan Oxygenase/metabolism ; src-Family Kinases/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Worthington, Andrew C. [Verfasser] ; Lee, Boon L. [Verfasser]
    Brisbane QLD : Queensland Univ. of Techn., School of Economics and Finance
    Published 2005
    Staff View
    Type of Medium:
    book
    Publication Date:
    2005
    Keywords:
    Produktivität ; Hochschule ; Arbeitspapier ; Effizienz ; Australien
    Language:
    English

    FIS Bildung Literaturdatenbank
  3. 3
    Staff View
    Type of Medium:
    article
    Publication Date:
    2022
    Keywords:
    Lehre ; Staat ; Studium ; Studiendauer ; Studienerfolg ; Hochschule ; Student ; Ausland ; Großbritannien
    In:
    Higher education quarterly, Bd. 76 (2022) H. 2, S. 399-421, 0263-9769
    0951-5224
    Language:
    English

    FIS Bildung Literaturdatenbank
  4. 4
    Staff View
    Publication Date:
    2018-02-10
    Publisher:
    The American Association of Immunologists (AAI)
    Print ISSN:
    0022-1767
    Electronic ISSN:
    1550-6606
    Topics:
    Medicine
    Published by:
    http://www.aai.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2018-02-23
    Publisher:
    American Society of Hematology (ASH)
    Print ISSN:
    0006-4971
    Electronic ISSN:
    1528-0020
    Topics:
    Biology
    Medicine
    Keywords:
    Immunobiology and Immunotherapy, Platelets and Thrombopoiesis
    Published by:
    http://www.hematology.org/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Staff View
    Publication Date:
    2018-08-07
    Publisher:
    The American Association of Immunologists (AAI)
    Print ISSN:
    0022-1767
    Electronic ISSN:
    1550-6606
    Topics:
    Medicine
    Published by:
    http://www.aai.org/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Nechvatalova, J., Bartol, S. J. W., Chovancova, Z., Boon, L., Vlkova, M., van Zelm, M. C.
    The American Association of Immunologists (AAI)
    Published 2018
    Staff View
    Publication Date:
    2018-09-18
    Publisher:
    The American Association of Immunologists (AAI)
    Print ISSN:
    0022-1767
    Electronic ISSN:
    1550-6606
    Topics:
    Medicine
    Published by:
    http://www.aai.org/

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    KASRAN, A. ; BOON, L. ; WORTEL, C. H. ; HOGEZAND, R. A. ; SCHREIBER, S. ; GOLDIN, E. ; BOER, M. ; GEBOES, K. ; RUTGEERTS, P. ; CEUPPENS, J. L.

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background:  The ligation of CD40 by CD154 is a critical step in the interaction between APC and T cells. In animals, antagonizing CD40L-CD40 has been shown to reduce the severity of several autoimmune and inflammatory disorders, including experimental colitis.Aim:  To investigate tolerability and safety of an antagonist chimeric monoclonal anti-human CD40 antibody (ch5D12) for treatment of Crohn's disease.Method:  ch5D12 was administrated to 18 patients with moderate to severe Crohn's disease in a single dose, open-label dose-escalation phase I/IIa study.Results:  ch5D12 plasma concentrations increased dose-dependently after infusion. Two patients developed an anti-ch5D12 antibody response. Overall response and remission rates were 72 and 22%, respectively with no evidence for a dose–response effect. Treatment with ch5D12 reduced microscopic disease activity and intensity of the lamina propria cell infiltrate, but did not alter percentages of circulating T and B cells. ch5D12 was well tolerated, although some patients experienced headache, muscle aches, or joint pains, which may have been related to the study drug.Conclusions:  Antagonizing CD154–CD40 interactions with ch5D12 is a promising therapeutic approach for remission induction in Crohn's disease.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2036.2005.02526.x

    Articles: DFG German National Licenses
  9. 9
    Bonne, R.W. ; Boon, L. ; Schoonman, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0368-1874
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0368-1874(78)89009-1

    Articles: DFG German National Licenses
  10. 10
    Bonne, R.W. ; Boon, L. ; Schoonman, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-0728
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0022-0728(78)80034-5

    Articles: DFG German National Licenses
  11. 11
    Boon, L. ; Metselaar, R.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-2738
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-2738(85)90044-X

    Articles: DFG German National Licenses
  12. 12
    Miles, R D ; Reece, P W ; Boon, L
    Springer
    Published 1998
    Staff View
    ISSN:
    1573-1995
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Electrical Engineering, Measurement and Control Technology
    Notes:
    Abstract This paper begins with an introduction to DAVIC, with particular reference to its objectives and plans. It then considers the split of the functional model into the three roles — service consumer system, delivery system and service provider system. Once the vertical split of the functional model has been considered the horizontal split into S1-S4 levels is covered. The paper then expands on the concepts of session and connection control through the use of the S2, S3 and S4 levels in the set-up, transfer and release of a user-to-network session and the end-to-end control of the user-to-user session. Finally, future plans/directions for DAVIC are considered, along with the adoption of Internet technologies within the DAVIC specifications.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1009670015945

    Articles: DFG German National Licenses