Search Results - (Author, Cooperation:K. Ueki)
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1M. Okada-Iwabu ; T. Yamauchi ; M. Iwabu ; T. Honma ; K. Hamagami ; K. Matsuda ; M. Yamaguchi ; H. Tanabe ; T. Kimura-Someya ; M. Shirouzu ; H. Ogata ; K. Tokuyama ; K. Ueki ; T. Nagano ; A. Tanaka ; S. Yokoyama ; T. Kadowaki
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-11-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adenylate Kinase/metabolism ; Adiponectin/metabolism/pharmacology ; Adipose Tissue, White/drug effects/metabolism/pathology ; Administration, Oral ; Animals ; Diabetes Mellitus, Type 2/complications/*drug therapy/metabolism/prevention & ; control ; Diet, High-Fat ; Drug Evaluation, Preclinical ; Dyslipidemias/drug therapy ; Enzyme Activation/drug effects ; Glucose Intolerance/drug therapy ; Inflammation/drug therapy ; Insulin Resistance ; Liver/drug effects/metabolism/pathology ; Longevity/*drug effects ; Mice ; Mitochondria/drug effects/metabolism ; Muscle Fibers, Skeletal/cytology/drug effects ; Muscles/cytology ; Obesity/complications/drug therapy/genetics/*physiopathology ; Oxidative Stress/drug effects ; PPAR alpha/metabolism ; Piperidines/administration & dosage/metabolism/*pharmacology/therapeutic use ; Receptors, Adiponectin/*agonists/deficiency/genetics/metabolism ; Signal Transduction/drug effects ; Small Molecule Libraries/chemistry ; Transcription Factors/biosynthesis ; Triglycerides/metabolismPublished by: -
2Kobayashi, M., Ohsugi, M., Sasako, T., Awazawa, M., Umehara, T., Iwane, A., Kobayashi, N., Okazaki, Y., Kubota, N., Suzuki, R., Waki, H., Horiuchi, K., Hamakubo, T., Kodama, T., Aoe, S., Tobe, K., Kadowaki, T., Ueki, K.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-07-31Publisher: The American Society for Microbiology (ASM)Print ISSN: 0270-7306Electronic ISSN: 1098-5549Topics: BiologyMedicinePublished by: -
3Kumanishi, T. ; Ikuta, F. ; Yamamoto, T. ; Maruyama, N. ; Nishida, K. ; Ueki, K.
Oxford, UK : Blackwell Publishing Ltd
Published 1975Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
4Kurihara, T. ; Kawakami, S. ; Ueki, K. ; Takahashi, Y.
Oxford, UK : Blackwell Publishing Ltd
Published 1974Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
5Yamauchi, T. ; Kamon, J. ; Minokoshi, Y. ; Ito, Y. ; Waki, H. ; Uchida, S. ; Yamashita, S. ; Noda, M. ; Kita, S. ; Ueki, K. ; Eto, K. ; Akanuma, Y. ; Froguel, P. ; Foufelle, F. ; Ferre, P. ; Carling, D. ; Kimura, S. ; Nagai, R. ; Kahn, B.B. ; Kadowaki, T.
[s.l.] : Nature Publishing Group
Published 2002Staff ViewISSN: 1546-170XSource: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] Adiponectin (Ad) is a hormone secreted by adipocytes that regulates energy homeostasis and glucose and lipid metabolism. However, the signaling pathways that mediate the metabolic effects of Ad remain poorly identified. Here we show that phosphorylation and activation of the 5′-AMP-activated ...Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
7Nagoshi, M. ; Fukuda, Y. ; Suzuki, T. ; Ueki, K. ; Tokiwa, A. ; Kikuchi, M. ; Syono, Y. ; Tachiki, M.
Amsterdam : ElsevierStaff ViewISSN: 0921-4534Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0922-338XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Process Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0031-9422Keywords: Nicotiana tabacum ; Solanaceae ; cultured tobacco cells ; divalent cations. ; enzyme secretion ; phosphataseSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0385-6380Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Process Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1432-1904Source: Springer Online Journal Archives 1860-2000Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1432-1998Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0040-6090Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
15Matsutani, M. ; Nakamura, O. ; Nagashima, T. ; Asai, A. ; Fujimaki, T. ; Tanaka, H. ; Nakamura, M. ; Ueki, K. ; Tanaka, Y. ; Matsuda, T.
Springer
Published 1994Staff ViewISSN: 0942-0940Keywords: Intra-operative radiation therapy ; glioblastoma ; metastatic brain tumour ; radiation therapySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary In radiation therapy for malignant brain tumours, the dose of radiation that can be safely delivered to a tumour is limited by the radiation tolerance of the adjacent normal brain tissue. Among various radiation modalities to produce local tumour eradication without unacceptable complications, we chose a large, single irradiation dose during the operation (intra-operative radiation therapy, IORT). In contrast to X-ray or Cobalt-60 gamma ray irradiation, IORT with a high-energy electron beam delivered by the Shimadzu 20 MeV betatron provides acceptable dose homogeneity with rapid fall-off of the radiation dose beyond the treatment volume. Thus, IORT has the advantage of precise demarcation of the target volume, minimum damage to surrounding normal tissues, and a high absorbed target dose (15–25 Gy in 5–10 min). On the basis of our experience with 170 patients treated by IORT, we established the treatment indications and method in patients with malignant brain tumours. IORT with a dose of 15–25 Gy was delivered to widely resected tumours followed by external radiation therapy. No acute or subacute complications were observed. Treatment results of 30 patients with glioblastoma treated by IORT (mean 18.3 Gy) combined with external radiation therapy (mean 58.5 Gy) resulted in a median survival of 119 weeks and a 2-year survival rate of 61%.Type of Medium: Electronic ResourceURL: -
16Nakamura, O. ; Matsutani, M. ; Shitara, N. ; Okamoto, K. ; Kaneko, M. ; Nakamura, H. ; Asai, A. ; Ueki, K. ; Shimizu, T. ; Tanaka, Y. ; Takakura, K.
Springer
Published 1994Staff ViewISSN: 0942-0940Keywords: Intra-operative radiation therapy ; metastatic braintumours ; lung cancerSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary In patients with brain metastasis from lung cancer, we have been able to control local recurrence in approximately 80% of cases. But many of them tend to show brain atrophy with mental deterioration developing a few months after whole brain radiation. To prevent brain atrophy, we have attempted treating patients, whose metastasis was diagnosed as single, by intra-operative radiotherapy (IOR) alone following surgical resection. Among 43 patients, 19 patients who had no metastases other than the brain metastases, were chosen as subjects for active treatment (surgical resection+IOR). Their 1-year survival rate was 75%. Fourteen out of 27 patients with brain métastases from lung cancer received active treatment and their 1-year survival rate was 74%. This result was not inferior to our result of 71 patients who received surgical resection and whole brain irradiation. When no preventive whole brain irradiation was performed, patients were observed every 8 weeks by CT scan in order to ascertain tumour recurrence limited to the treated site or appearance of any new metastatic lesion remote from the treated site. Among all 43 patients, local recurrence was recognized in 7 cases and remote recurrence was observed in 7 cases. Within 6 months, local and remote recurrence was found in 3 cases each. These results were almost the same as those for the usual therapy (surgery plus whole brain irradiation). If such a new lesion is detected, additional radiation can be performed with the possibility of achieving complete remission.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1432-1920Keywords: Cyst, retrocebellar ; Malformations, posterior fossaSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary A detailed analysis of the angiographic findings with a congenital retrocerebellar arachnoid cyst in an infant is reported. The angiographic features are a huge retrocerebellar extra-axial avascular mass compressing and displacing the fourth ventricle anteriorly, dysgenesis of the cerebellum, a tight posterior fossa and transtentorial upward herniation of the monticulus and brainstem.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1573-0972Source: Springer Online Journal Archives 1860-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Abstract A newly isolated, anaerobic, mesophillic bacterium, Clostridium sp. strain YK-3, ferments pentoses, hexoses, oligosaccharides and polysaccharides, such as soluble starch and glycogen, to ethanol and acetate. The potential of this strain for ethanol and amylase production has been examined. Ethanol was the major product and acetate a minor one. The organism could grow with soluble starch in the presence of 40 g ethanol/l. Extracellular α-amylase activity was detected when the strain was cultivated with soluble starch, glycogen or dextrin. The optimum pH of this amylase was 5.5 to 7.5 with an optimum temperature of 50°C.Type of Medium: Electronic ResourceURL: