Search Results - (Author, Cooperation:K. Oshima)

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  1. 1
    Ohtaka-Maruyama, C., Okamoto, M., Endo, K., Oshima, M., Kaneko, N., Yura, K., Okado, H., Miyata, T., Maeda, N.
    American Association for the Advancement of Science (AAAS)
    Published 2018
    Staff View
    Publication Date:
    2018-04-20
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Development
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2013-06-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Anti-Bacterial Agents/pharmacology ; Bacteria/metabolism ; Bile Acids and Salts/metabolism ; Carcinoma, Hepatocellular/complications/etiology/metabolism/prevention & control ; *Cell Aging/drug effects ; Cells, Cultured ; Cytokines/metabolism/secretion ; DNA Damage/drug effects ; Deoxycholic Acid/blood/*metabolism ; Dietary Fats/adverse effects/pharmacology ; Disease Models, Animal ; Fatty Liver/complications/pathology ; Gastrointestinal Tract/drug effects/*metabolism/*microbiology ; Hepatic Stellate Cells/cytology/drug effects/metabolism/*secretion ; Humans ; Interleukin-1beta/deficiency ; Liver Neoplasms/complications/etiology/*metabolism/prevention & control ; Male ; Mice ; Mice, Inbred C57BL ; Non-alcoholic Fatty Liver Disease ; Obesity/chemically induced/*metabolism ; Phenotype ; Risk Factors
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2013-07-12
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adult ; Animals ; Cell Proliferation ; Clostridium/classification/genetics/*immunology ; Colitis/microbiology/pathology ; Colon/immunology/microbiology ; Disease Models, Animal ; Feces/microbiology ; Germ-Free Life ; Humans ; Inducible T-Cell Co-Stimulator Protein/metabolism ; Interleukin-10/metabolism ; Male ; Metagenome/genetics/*immunology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, SCID ; RNA, Ribosomal, 16S/genetics ; Rats ; Rats, Inbred F344 ; T-Lymphocytes, Regulatory/cytology/*physiology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2011-01-29
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Acetates/*metabolism ; Animals ; Bifidobacterium/genetics/*metabolism ; Cercopithecus aethiops ; Escherichia coli Infections/microbiology/*prevention & control ; Escherichia coli O157/*physiology ; Gene Expression Profiling ; Genome, Bacterial ; Mice ; Molecular Sequence Data ; Vero Cells
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Lai, C.-H. ; Oshima, K. ; Slots, J. ; Listgarten, M. A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1992
    Staff View
    ISSN:
    1600-0765
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Wolinella recta has been associated with adult periodontitis, but its role in the disease remains uncertain. This report clarifies the distribution of W. recta in periodontally healthy and diseased subjects, and treated patients with recurrent disease. A specific polyclonal rabbit antiserum against W. recta strain 372 was used for indirect immunofluorescence localization of W. recta in dental plaque from untreated and treated patients. Supragingival plaque was collected from 15 periodontally healthy individuals (H), 10 adults with mild gingivitis (G1), 8 with severe gingivitis (G2) and 15 with periodontitis (AP). Subgingival samples from 23 diseased sites (G2 and AP) were examined as well. There was a significant difference (p = 0.000) between the proportions of W. recta in subgingival (4.4%) vs. supragingival (0.3%) plaque samples from AP. A significant difference (p = 0.000) in W. recta proportions was also detected between subgingival plaque samples of AP (4.4%) vs. G2 (1.2%). No significant difference in the mean % of W. recta was found between supragingival plaque of AP (0.3%) and G2 (0%), and samples of G1 (0.01%) and H (0.1%). In a separate study, 85 adults previously treated for moderate to severe adult periodontitis were monitored over a 12-month period for evidence of disease recurrence. Recurrent disease was detected at 32 sites in 18 subjects. Of these, 20 sites in 13 subjects were positive for W. recta. With subjects as the experimental unit, a significant increase in the proportions of W. recta was found at sites with recurrent disease (3.12%) as compared to stable, paired control sites (0.24%), but only when sites with breakdown and positive for W. recta were compared with their controls. These results indicate that W. recta is associated with some, but not all sites with advanced adult periodonlilis. The association of W. recta with gingivitis was not statistically significant.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0765.1992.tb02079.x

    Articles: DFG German National Licenses
  6. 6
    Ishii, T. ; Naito, K. ; Oshima, K. ; Hamaguchi, Y.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-3697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0022-3697(71)80025-2

    Articles: DFG German National Licenses
  7. 7
    Kume, T ; Oshima, K ; Shinohara, T ; Takeo, H ; Yamashita, Y ; Shirakusa, T ; Kikuchi, M

    Oxford, U.K. and Cambridge, USA : Blackwell Publishing Ltd
    Published 1999
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Epstein–Barr virus (EBV) has been demonstrated in about 10% of gastric carcinomas. However, the pathogenetic role of EBV in gastric carcinoma is uncertain. We compared the rate of apoptotic cell death, cell proliferation and the expression of apoptosis-related proteins in gastric carcinomas with or without EBV.〈section xml:id="abs1-2"〉〈title type="main"〉Methods and resultsEpstein–Barr virus was detected in 40 gastric carcinomas by EBV-encoded small RNA-1 in-situ hybridization. Apoptotic cell death, MIB-1, p53, bcl-2 and bcl-x were examined by the terminal deoxynucleotidyl-mediated dUTP-nick end labelling method and immunohistochemistry. We also included 40 age-, sex- and disease stage-matched EBV-negative cases as a control. The number of apoptotic cells was significantly lower in EBV-positive (20 ± 15.1/1000 cells) and bcl-2-positive (17 ± 12.9/1000 cells) tumours than in EBV-negative (43 ± 37.1) and bcl-2-negative tumours (38 ± 32.1, P 〈 0.001, P 〈 0.001, respectively). bcl-2 immunostaining was significantly higher in EBV-positive tumours (24 cases) than in EBV-negative tumours (12 cases, P 〈 0.05). There was no significant difference in bcl-x and p53 expression between EBV-positive and -negative tumours. The number of MIB-1-positive cells in EBV-positive tumours (237 ± 161/1000) was significantly lower than in EBV-negative tumours (480 ± 208/1000 cells, P 〈 0.001).〈section xml:id="abs1-3"〉〈title type="main"〉ConclusionsA low rate of apoptosis and high bcl-2 expression were recognized in EBV-positive gastric carcinomas, suggesting that bcl-2 protein is the main inhibitor of apoptosis in EBV-positive carcinomas. In addition, the low apoptotic and proliferative activities may reflect a low biological activity in EBV-positive gastric carcinomas.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2559.1999.00686.x

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(88)81169-0

    Articles: DFG German National Licenses
  9. 9
    Oshima, K. ; Urayama, H. ; Yamochi, H. ; Saito, G.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0921-4534(88)90218-3

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-4534(93)90790-W

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-4534(91)91466-H

    Articles: DFG German National Licenses
  12. 12
    Oshima, K. ; Urayama, H. ; Yamochi, H. ; Saito, G.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-4534(88)90218-3

    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-4534(94)90590-8

    Articles: DFG German National Licenses
  14. 14
    Oshima, K. ; Johnson, C.L. ; Gorbman, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0016-6480
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0016-6480(72)90184-0

    Articles: DFG German National Licenses
  15. 15
    Oshima, K. ; Gorbman, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0016-6480
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0016-6480(69)90225-1

    Articles: DFG German National Licenses
  16. 16
    Oshima, K. ; Gorbman, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0016-6480
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0016-6480(66)90059-1

    Articles: DFG German National Licenses
  17. 17
    Oshima, K. ; Gorbman, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0016-6480
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0016-6480(69)90156-7

    Articles: DFG German National Licenses
  18. 18
    Oshima, K. ; Gorbman, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0016-6480
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0016-6480(69)90226-3

    Articles: DFG German National Licenses
  19. 19
    Oshima, K. ; Gorbman, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0016-6480
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0016-6480(66)90070-0

    Articles: DFG German National Licenses
  20. 20
    Ishii, T. ; Naito, K. ; Oshima, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0038-1098
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0038-1098(70)90443-6

    Articles: DFG German National Licenses