Search Results - (Author, Cooperation:K. Ohnishi)
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1A. Gould ; A. Udalski ; I. G. Shin ; I. Porritt ; J. Skowron ; C. Han ; J. C. Yee ; S. Kozlowski ; J. Y. Choi ; R. Poleski ; L. Wyrzykowski ; K. Ulaczyk ; P. Pietrukowicz ; P. Mroz ; M. K. Szymanski ; M. Kubiak ; I. Soszynski ; G. Pietrzynski ; B. S. Gaudi ; G. W. Christie ; J. Drummond ; J. McCormick ; T. Natusch ; H. Ngan ; T. G. Tan ; M. Albrow ; D. L. DePoy ; K. H. Hwang ; Y. K. Jung ; C. U. Lee ; H. Park ; R. W. Pogge ; F. Abe ; D. P. Bennett ; I. A. Bond ; C. S. Botzler ; M. Freeman ; A. Fukui ; D. Fukunaga ; Y. Itow ; N. Koshimoto ; P. Larsen ; C. H. Ling ; K. Masuda ; Y. Matsubara ; Y. Muraki ; S. Namba ; K. Ohnishi ; L. Philpott ; N. J. Rattenbury ; T. Saito ; D. J. Sullivan ; T. Sumi ; D. Suzuki ; P. J. Tristram ; N. Tsurumi ; K. Wada ; N. Yamai ; P. C. Yock ; A. Yonehara ; Y. Shvartzvald ; D. Maoz ; S. Kaspi ; M. Friedmann
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-07-06Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Cardinez, C., Miraghazadeh, B., Tanita, K., da Silva, E., Hoshino, A., Okada, S., Chand, R., Asano, T., Tsumura, M., Yoshida, K., Ohnishi, H., Kato, Z., Yamazaki, M., Okuno, Y., Miyano, S., Kojima, S., Ogawa, S., Andrews, T. D., Field, M. A., Burgio, G., Morio, T., Vinuesa, C. G., Kanegane, H., Cook, M. C.
Rockefeller University Press
Published 2018Staff ViewPublication Date: 2018-11-06Publisher: Rockefeller University PressPrint ISSN: 0022-1007Electronic ISSN: 1540-9538Topics: MedicineKeywords: Immunodeficiency, Human Disease GeneticsPublished by: -
3Yoshikawa, M. ; Saitoh, K. ; Ohshima, T. ; Itoh, H. ; Nashiyama, I. ; Yoshida, S. ; Okumura, H. ; Takahashi, Y. ; Ohnishi, K.
[S.l.] : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Oxide layers etched at an angle were fabricated on a 6H-SiC substrate by varying etching time in diluted hydrofluoric acid, and 6H-SiC metal–oxide–semiconductor structures with various oxide thicknesses were formed. High-frequency capacitance–voltage measurements were carried out for determining the change in gate voltages corresponding to the midgap condition as a function of the thickness of the oxide layer, and the depth profile of trapped charge density in the oxide was estimated from the result. It is found that negative charges build up near the 6H-SiC/SiO2 interface, and that positive charges accumulate in the region at 40 nm from the interface. No significant difference is observed in the depth profiles of the trapped charge density between the oxide layers on the carbon and silicon faces. The origin of these trapped charges is discussed in conjunction with the carbon-related compounds in the oxide layers. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
4Yamada, K. ; Asahi, H. ; Tampo, H. ; Imanishi, Y. ; Ohnishi, K. ; Asami, K.
Woodbury, NY : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Polycrystalline GaN layers were grown on W, Mo, Ta, and Nb metal substrates by gas-source molecular-beam epitaxy using an ion-removal, electron-cyclotron-resonance radical cell. X-ray diffraction rocking curves showed preferential GaN(0002) or GaN(10–11) orientations. The grain sizes ranged from 100 to 800 nm. Strong photoluminescence (PL) emission without yellow luminescence was observed from these polycrystalline GaN layers. At 77 K, PL peaks at 3.46 and 3.26 eV were observed, and their temperature dependence fit a simple relation based on the number of phonons. The higher-energy peak probably was due to the free excitonic transition in hexagonal GaN. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
5Ohnishi, K. ; Kutsukake, K. ; Suzuki, H. ; Lino, T.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: We have studied the molecular mechanism of the negative regulation by flgM of the late operons of the flagellar regulon of Salmonella typhimurium. A 7.8 kDa protein that was identified as the flgM gene product was purified to homogeneity; its amino-terminal sequence was identical to the deduced sequence except for the lack of the initiating methionine. The purified FlgM repressed transcription from the fliC promoter, one that is activated by the sigma factor, FliA (σF). No DNA-binding activity was detected in FlgM. Chemical cross-linking experiments showed that the purified FlgM bound to σF and disturbed Its ability to form a complex with RNA polymerase core enzyme. These results indicate that FlgM is a novel type of negative regulator that probably inactivates the flagellum-specific sigma factor through direct interaction, i.e. it is an anti-sigma factor.Type of Medium: Electronic ResourceURL: -
6HIGUCHI, T. ; ISHIKAWA, O. ; HAYASHI, H. ; OHNISHI, K. ; MIYACHI, Y.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1365-2230Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The disaccharide content of the chondroitinase-digestible glycosaminoglycans (GAGs) extracted from 6–mm skin punch biopsies from the atrophic and sclerotic skin of two patients with Werner's syndrome (WS) were determined using high-performance liquid chromatography after 1–phenyl-3–methyl-5–pyrazolone labelling. The total amount of main disaccharides was significantly decreased in the atrophic lesions of WS. In the atrophic forearm skin, the decrease in the main disaccharide unit of hyaluronic acid, ΔDi-HA, and the increase in the ratio of the main disaccharide unit of dermatan sulphate, ΔDi-4S, to ΔDi-HA were significant vs. normal control (P 〈0.01 and 0.05, respectively). The sclerotic skin showed an increase in ΔDi-4S (DS) (P 〈 0.05) and a decrease in ΔDi-HA (P 〈 0.02) compared with normal controls, as well as a significantly higher ratio of ADi-4S (DS)/ΔDi-HA compared with normal controls (P 〈 0.0002) and systemic sclerosis patients (SSc; P 〈 0.02). No other statistical difference was found in the amount of each main disaccharide unit between the sclerotic skin of WS and SSc. Histological examination revealed that the atrophic skin showed thinning of the dermis with a slight increase of fine collagen bundles, whereas the sclerotic skin demonstrated a thickened dermis with prominent deposition of fine collagen bundles in the deep dermis. In SSc, thickening of the whole dermis, composed of hyalinized or swollen collagen bundles, was found. These results suggest mat alterations of disaccharide components in WS may differentiate the atrophic skin changes from the sclerotic skin changes, while the mechanisms for abnormal fibrosis remain to be elucidated.Type of Medium: Electronic ResourceURL: -
7TAMURA, A. ; OHNISHI, K. ; ISHIKAWA, O. ; MIYACHI, Y.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary DNA-ploidy in primary cutaneous squamous cell carcinomas which had developed from different preceding clinical lesions was examined by flow cytometry using paraffin-embedded blocks. DNA-aneuploidy was detected in none of 15 squamous cell carcinomas arising from a burn scar. On the other hand. 12 of 26 squamous cell carcinomas arising from sun-damaged skin in the elderly, and two of four arising from chronic radiodermatitis, showed aneuploid patterns. A significantly higher incidence of DNA-aneuploidy was observed in squamous cell carcinomas arising from sun-damaged skin than those from a burn scar (P 〈 0.01): the mean diameter size of the former was significantly smaller than that of the latter (P 〈 0.0001). The mean age of patients with aneuploid tumours (74·2 ± 9·2: years ± standard deviation (SD)) was significantly higher than that with diploid tumours (64·1 ± 13·8) (P 〈 0〈01).Type of Medium: Electronic ResourceURL: -
8ISHIKAWA, O. ; TAMURA, T. ; OHNISHI, K. ; MIYACHI, Y. ; ISHII, K.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We report a 57-year-old woman with systemic sclerosis (SSc) who died suddenly, following a haemoptysis. At post-mortem, systemic necrotizing angiitis of small vessels was observed in several organs. Necrotizing angiitis has been reported as a rare complication of systemic sclerosis, and is usually lethal.Type of Medium: Electronic ResourceURL: -
9ISHIKAWA, O. ; WARITA, S. ; OHNISHI, K. ; MIYACHI, Y.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We report a 17-year-old Japanese girl with typical clinical features of recessive dystrophic epidermolysis bullosa (RDEB). She had initially been diagnosed as suffering from systemic sclerosis because her skin became sclerotic at the age of 21 months, and there was no apparent blister formation. She subsequently developed severe dystrophic skin changes. However, there was histological evidence of subepidermal cleavage, diminished basement membrane zone immunohistochemical reactivity to anti-type VII collagen monoclonal antibody, and markedly decreased numbers of anchoring fibrils on electron microscopy. Although both the clinical and laboratory findings support a diagnosis of RDEB, we cannot exclude the possibility that our patient might represent a new clinical entity.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0003-9861Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0921-4526Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
12Nakajima, Y. ; Amamiya, Y. ; Ohnishi, K. ; Terasaki, I. ; Maeda, A. ; Uchinokura, K.
Amsterdam : ElsevierStaff ViewISSN: 0921-4534Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0922-338XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Process Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0922-338XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Process Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0022-1139Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0022-1139Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: