Search Results - (Author, Cooperation:K. Masuda)
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1K. Abe, K. Hiraide, K. Ichimura, Y. Kishimoto, K. Kobayashi, M. Kobayashi, S. Moriyama, M. Nakahata, H. Ogawa, K. Sato, H. Sekiya, T. Suzuki, O. Takachio, A. Takeda, S. Tasaka, M. Yamashita, B.S. Yang, N.Y. Kim, Y.D. Kim, Y. Itow, K. Kanzawa, K. Masuda, K. Martens, Y. Suzuki, B. D. Xu, K. Miuchi, N. Oka, Y. Takeuchi, Y.H. Kim, K.B. Lee, M.K. Lee, Y. Fukuda, M. Miyasaka, K. Nishijima, K. Fushimi, G. Kanzaki and S. Nakamura
Institute of Physics Publishing (IOP)
Published 2018Staff ViewPublication Date: 2018-12-21Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
2A. Gould ; A. Udalski ; I. G. Shin ; I. Porritt ; J. Skowron ; C. Han ; J. C. Yee ; S. Kozlowski ; J. Y. Choi ; R. Poleski ; L. Wyrzykowski ; K. Ulaczyk ; P. Pietrukowicz ; P. Mroz ; M. K. Szymanski ; M. Kubiak ; I. Soszynski ; G. Pietrzynski ; B. S. Gaudi ; G. W. Christie ; J. Drummond ; J. McCormick ; T. Natusch ; H. Ngan ; T. G. Tan ; M. Albrow ; D. L. DePoy ; K. H. Hwang ; Y. K. Jung ; C. U. Lee ; H. Park ; R. W. Pogge ; F. Abe ; D. P. Bennett ; I. A. Bond ; C. S. Botzler ; M. Freeman ; A. Fukui ; D. Fukunaga ; Y. Itow ; N. Koshimoto ; P. Larsen ; C. H. Ling ; K. Masuda ; Y. Matsubara ; Y. Muraki ; S. Namba ; K. Ohnishi ; L. Philpott ; N. J. Rattenbury ; T. Saito ; D. J. Sullivan ; T. Sumi ; D. Suzuki ; P. J. Tristram ; N. Tsurumi ; K. Wada ; N. Yamai ; P. C. Yock ; A. Yonehara ; Y. Shvartzvald ; D. Maoz ; S. Kaspi ; M. Friedmann
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-07-06Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Staff View
Publication Date: 2012-06-16Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Carbon Isotopes/*analysis ; Cedrus/*chemistry ; *Cosmic Radiation ; JapanPublished by: -
4Nguyen, C., Schlesinger, K. J., James, T. W., James, K. M., Sah, R. L., Masuda, K., Carlson, J. M.
Royal Society
Published 2018Staff ViewPublication Date: 2018-08-30Publisher: Royal SocietyElectronic ISSN: 2054-5703Topics: Natural Sciences in GeneralKeywords: medical physicsPublished by: -
5Kanazawa, Y. ; Yamane, H. ; Shinohara, S. ; Kuribayashi, S. ; Momozono, Y. ; Yamato, Y. ; Kojima, M. ; Masuda, K.
Oxford, UK : Blackwell Science Ltd
Published 1996Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: Epimeric conversion of 2-deoxy-2-fluoro-d-glucose (FDG) to its 2-epimer 2-deoxy-2-fluoro-d-mannose (FDM) proved by 19F NMR has been shown to reflect the brain activity. To examine the feasibility of FDG as a new NMR probe for in vivo functional monitoring, we studied here the fundamental NMR properties of metabolites, spectral assignments, and reliability of NMR quantification. Metabolites confirmed in brain besides FDM-6-phosphate were as follows: FDG-1-phosphate, FDG-1,6-bisphosphate, FDM-1-phosphate, FDM-1,6-bisphosphate, and FDG and FDM derivatives of nucleotide diphosphate. NMR quantification of these metabolites was evaluated in comparison with the method of 18F-labeled FDG. In the NMR functional study using FDG, where a high dose is inevitable, the dose dependence of uptake was investigated. FDG uptake in mouse brain was shown to be in the range of interpretation using the biochemical parameters of enzymes for glucose uptake as long as a dose of 〈200 mg/kg was used.Type of Medium: Electronic ResourceURL: -
6Ippo¯shi, T. ; Takita, K. ; Murakami, K. ; Masuda, K. ; Kudo, H. ; Seki, S.
[S.l.] : American Institute of Physics (AIP)
Published 1988Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The Hg content of anodic sulfide films on Hg1−xCdxTe (MCT) were investigated for as-grown and heat-treated films by using 30–40-MeV O5+ ion backscattering. Heat treatments were performed in a vacuum for 60 min at various temperatures up to 300 °C for the samples with x=0.20 and up to 350 °C for the samples with x=0.30 and 0.35. A significant Hg content of about 15 at. % of Cd was found in the as-grown anodic sulfide film on MCT samples with x=0.20, 0.30, and 0.35. After heat treatment above 260 °C for x=0.30 and 0.35 and above 210–240 °C for x=0.20, the Hg atoms were removed from the films, and Hg deficient layers were formed near the interface region of the MCT crystal. This suggests that the residual Hg in the anodic sulfide films introduced during the sulfidization process plays an important role toward the degradation of the passivation properties of the sulfide film on MCT.Type of Medium: Electronic ResourceURL: -
7Takita, K. ; Ippo¯shi, T. ; Murakami, K. ; Masuda, K. ; Kudo, H. ; Seki, S.
[S.l.] : American Institute of Physics (AIP)
Published 1986Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Dissociation and evaporation of Hg from the near-surface region of Hg1−xCdxTe crystals was investigated, up to several microns, by means of 40-MeV O5+ backscattering. Samples with x=0.18 and 0.32 were heat treated in a vacuum for 60 min at various temperatures up to 320 and 340 °C, respectively. The change of the backscattering spectra with the temperature of heat treatment indicated that the Hg atoms outdiffused partly from the near-surface region of the crystals at higher temperatures than 280 and 320 °C for x=0.18 and 0.32, respectively. This behavior of outdiffusion is in contrast to the case of HgTe crystal.Type of Medium: Electronic ResourceURL: -
8UTSUNOMIYA, T. ; YAO, T. ; MASUDA, K. ; TSUNEYOSHI, M.
Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
Published 1996Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Recently, the expression of vimentin has been reported in some carcinomas. This study was designed to clarify the significance of vimentin expression in solid type poorly differentiated adenocarcinomas of the stomach. Immunohistochemically, 239 poorly differentiated adenocarcinomas with solid components of the stomach were stained for vimentin. Vimentin-positive cases were also stained by CAM 5.2 using serial mirror sections. We found 15 (6.3%) vimentin-positive cases. Twelve of them demonstrated varying amounts of rhabdoid-like cells. Eight cases diffusely co-expressed vimentin and cytokeratin simultaneously. In addition, four co-expressing cases showed positive staining with Keratin-903 which recognizes the high molecular-weight cytokeratin. Most of the co-expressing cases showed a diffuse proliferation of polygonal tumour cells with focal cell-to-cell contact. The prognosis of the co-expressing cases was poor in comparison with that of the 89 vimentin-negative tumours (P 〈 0.05).Type of Medium: Electronic ResourceURL: -
9Maeda, S. ; Ohmori, K. ; Yasuda, N. ; Kurata, K. ; Sakaguchi, M. ; Masuda, K. ; Ohno, K. ; Tsujimoto, H.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2222Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background Since dogs frequently develop allergic diseases, similar to those in humans, dogs represent a possible animal model for allergy in humans. In human atopic dermatitis (AD), CC chemokine receptor 4 (CCR4) has been shown to play an important role in the development of allergic inflammation of AD; however, the association between allergic reaction and CCR4 is not well understood in dogs.Objective To examine CCR4 expression in peripheral blood CD4+ cells in dogs that had AD and were experimentally sensitized with Japanese cedar pollen.Materials and methods Peripheral blood mononuclear cells (PBMCs) were isolated from 17 dogs with AD. The proportion of CCR4+ cells in peripheral blood CD4+ cells (CCR4/CD4) was evaluated by flow cytometry and compared with that in 10 healthy dogs. Similarly, in dogs that were experimentally sensitized to Japanese cedar pollen antigen, the proportion of CCR4/CD4 was examined pre- and post-sensitization.Results The proportion of CCR4/CD4 in dogs with AD was 40.3±3.3%, which was significantly higher than that in normal dogs (23.6±4.3%) (P〈0.01). In the experimentally sensitized dogs, the proportion of CCR4/CD4 was 25.4±2.6% at pre-sensitization and it was significantly increased (29.8±2.9%) at post-sensitization (P〈0.01).Conclusion The proportion of CCR4+ cells in peripheral blood CD4+ cells was measured in dogs with allergic conditions. The present findings indicate that CCR4+ cells may be involved in the pathogenesis of allergy in dogs as in humans.Type of Medium: Electronic ResourceURL: -
10Watanabe, T ; Oda, Y ; Tamiya, S ; Kinukawa, N ; Masuda, K ; Tsuneyoshi, M
Oxford UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Malignant peripheral nerve sheath tumours: high Ki67 labelling index is the significant prognostic indicator Aims: We investigated p53, Ki67, MDM2, and p21WAF1/CIP1 in order to evaluate its relationship with prognosis in malignant peripheral nerve sheath tumours (MPNST). Methods and results: In 49 cases of MPNSTs, the immunohistochemical studies of Ki67, p53, MDM2, p21WAF1/CIP1 and polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP) with direct sequencing of p53 were performed with the formalin-fixed paraffin-embedded tissue. In 43 cases with survival data available, an evaluation of the prognostic significance of clinicopathological factors was also carried out. A high Ki67 labelling index (LI) (〉25%) was correlated with a reduced survival rate in the 43 cases of MPNST (P=0.0106, log-rank test). Furthermore, there was a significant correlation between the Ki67 LI and the immunohistochemical expression of p53 or MDM2. In 17 MPNST cases, PCR amplification of exons 5 through 8 of the p53 gene was successful. One case showed a base change of codon 240 (AGT→AGC), but translated amino acid (Ser) remained unchanged. Multivariate Cox analysis of our series showed that the association of von Recklinghausen’s disease, tumour depth, and the presence of rhabdomyoblasts (malignant triton tumour) each had an independent negative impact on overall survival. Conclusion: High Ki67 LI (〉25%) was of significant prognostic value in MPNST.Type of Medium: Electronic ResourceURL: -
11Miyajima, K ; Oda, Y ; Oshiro, Y ; Tamiya, S ; Kinukawa, N ; Masuda, K ; Tsuneyoshi, M
Oxford UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Clinicopathological prognostic factors in soft tissue leiomyosarcoma: a multivariate analysis Aims: Prognostic factors affecting survival in cases of leiomyosarcoma of soft parts were investigated in this study. Methods and results: A retrospective study of 267 patients was carried out. This group comprised 142 females (53%) and 125 males (47%), whose ages ranged from 7 to 95 years (median 58 years). One hundred and five cases were superficially situated (arising from the skin or subcutis), while the remaining 162 cases were deeply situated (subfacial). Nineteen were cases of pleomorphic leiomyosarcoma where the diagnosis had been amended from malignant fibrous histiocytoma to leiomyosarcoma whilst under review. Of the 167 patients with follow-up data, 83 died of leiomyosarcoma. In univariate analysis, depth, tumour size (≥50 mm), mitotic rate of 〉20 per 10 high-power fields (HPF), tumour necrosis of 〉50% and a high stage according to the most recent American Joint Committee on Cancer (AJCC) staging for soft tissue sarcoma were found to lessen significantly the rate of survival (log rank test; P 〈 0.05). However, in multivariate analysis (Cox's proportional hazards model), tumour size and high AJCC stage were the only factors that were correlated independently with decreased survival. Conclusions: This study indicates that the most reliable prognostic parameters are tumour size and AJCC stage in leiomyosarcoma.Type of Medium: Electronic ResourceURL: -
12Toda, T. ; Segawa, M. ; Nomura, Y. ; Nonaka, I. ; Masuda, K. ; Ishihara, T. ; Suzuki, M. ; Tomita, I. ; Origuchi, Y. ; Ohno, K. ; Misugi, N. ; Sasaki, Y. ; Takada, K. ; Kawai, M. ; Otani, K. ; Murakami, T. ; Saito, K. ; Fukuyama, Y. ; Shimizu, T. ; Kanazawa, I. ; Nakamura, Y.
[s.l.] : Nature Publishing Group
Published 1993Staff ViewISSN: 1546-1718Source: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] Fukuyama type congenital muscular dystrophy (FCMD) is an autosomal recessive severe muscular dystrophy associated with an anomaly of the brain. Twenty–one FCMD families, 13 of them with consanguineous marriages, were analysed by genetic linkage analyses with polymorphic microsatellite markers ...Type of Medium: Electronic ResourceURL: -
13MIZOGUCHI, M. ; CHIKAKANE, K. ; GOH, K. ; ASAHINA, Y. ; MASUDA, K.
Oxford, UK : Blackwell Publishing Ltd
Published 1987Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A case of Sweet's syndrome is reported in a patient with Behçlet's disease. This association has not been reported outside Japan. The relationship of the two diseases is discussed.Type of Medium: Electronic ResourceURL: -
14Yamada, Y. ; Kagimoto, S. ; Kubota, A. ; Yasuda, K. ; Masuda, K. ; Someya, Y. ; Ihara, Y. ; Li, Q. ; Imura, H. ; Seino, S. ; Seino, Y.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0005-2787Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0003-2697Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
18Doke, T. ; Kikuchi, J. ; Shibamura, E. ; Masuda, K. ; Kasahara, K. ; Muraki, Y.
Amsterdam : ElsevierStaff ViewISSN: 0920-5632Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0921-4534Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0922-338XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Process Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: