Search Results - (Author, Cooperation:K. Masuda)

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  1. 1
  2. 2
    A. Gould ; A. Udalski ; I. G. Shin ; I. Porritt ; J. Skowron ; C. Han ; J. C. Yee ; S. Kozlowski ; J. Y. Choi ; R. Poleski ; L. Wyrzykowski ; K. Ulaczyk ; P. Pietrukowicz ; P. Mroz ; M. K. Szymanski ; M. Kubiak ; I. Soszynski ; G. Pietrzynski ; B. S. Gaudi ; G. W. Christie ; J. Drummond ; J. McCormick ; T. Natusch ; H. Ngan ; T. G. Tan ; M. Albrow ; D. L. DePoy ; K. H. Hwang ; Y. K. Jung ; C. U. Lee ; H. Park ; R. W. Pogge ; F. Abe ; D. P. Bennett ; I. A. Bond ; C. S. Botzler ; M. Freeman ; A. Fukui ; D. Fukunaga ; Y. Itow ; N. Koshimoto ; P. Larsen ; C. H. Ling ; K. Masuda ; Y. Matsubara ; Y. Muraki ; S. Namba ; K. Ohnishi ; L. Philpott ; N. J. Rattenbury ; T. Saito ; D. J. Sullivan ; T. Sumi ; D. Suzuki ; P. J. Tristram ; N. Tsurumi ; K. Wada ; N. Yamai ; P. C. Yock ; A. Yonehara ; Y. Shvartzvald ; D. Maoz ; S. Kaspi ; M. Friedmann
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-07-06
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    F. Miyake ; K. Nagaya ; K. Masuda ; T. Nakamura
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-06-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Carbon Isotopes/*analysis ; Cedrus/*chemistry ; *Cosmic Radiation ; Japan
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-08-30
    Publisher:
    Royal Society
    Electronic ISSN:
    2054-5703
    Topics:
    Natural Sciences in General
    Keywords:
    medical physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Kanazawa, Y. ; Yamane, H. ; Shinohara, S. ; Kuribayashi, S. ; Momozono, Y. ; Yamato, Y. ; Kojima, M. ; Masuda, K.

    Oxford, UK : Blackwell Science Ltd
    Published 1996
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: Epimeric conversion of 2-deoxy-2-fluoro-d-glucose (FDG) to its 2-epimer 2-deoxy-2-fluoro-d-mannose (FDM) proved by 19F NMR has been shown to reflect the brain activity. To examine the feasibility of FDG as a new NMR probe for in vivo functional monitoring, we studied here the fundamental NMR properties of metabolites, spectral assignments, and reliability of NMR quantification. Metabolites confirmed in brain besides FDM-6-phosphate were as follows: FDG-1-phosphate, FDG-1,6-bisphosphate, FDM-1-phosphate, FDM-1,6-bisphosphate, and FDG and FDM derivatives of nucleotide diphosphate. NMR quantification of these metabolites was evaluated in comparison with the method of 18F-labeled FDG. In the NMR functional study using FDG, where a high dose is inevitable, the dose dependence of uptake was investigated. FDG uptake in mouse brain was shown to be in the range of interpretation using the biochemical parameters of enzymes for glucose uptake as long as a dose of 〈200 mg/kg was used.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Ippo¯shi, T. ; Takita, K. ; Murakami, K. ; Masuda, K. ; Kudo, H. ; Seki, S.

    [S.l.] : American Institute of Physics (AIP)
    Published 1988
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The Hg content of anodic sulfide films on Hg1−xCdxTe (MCT) were investigated for as-grown and heat-treated films by using 30–40-MeV O5+ ion backscattering. Heat treatments were performed in a vacuum for 60 min at various temperatures up to 300 °C for the samples with x=0.20 and up to 350 °C for the samples with x=0.30 and 0.35. A significant Hg content of about 15 at. % of Cd was found in the as-grown anodic sulfide film on MCT samples with x=0.20, 0.30, and 0.35. After heat treatment above 260 °C for x=0.30 and 0.35 and above 210–240 °C for x=0.20, the Hg atoms were removed from the films, and Hg deficient layers were formed near the interface region of the MCT crystal. This suggests that the residual Hg in the anodic sulfide films introduced during the sulfidization process plays an important role toward the degradation of the passivation properties of the sulfide film on MCT.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Takita, K. ; Ippo¯shi, T. ; Murakami, K. ; Masuda, K. ; Kudo, H. ; Seki, S.

    [S.l.] : American Institute of Physics (AIP)
    Published 1986
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Dissociation and evaporation of Hg from the near-surface region of Hg1−xCdxTe crystals was investigated, up to several microns, by means of 40-MeV O5+ backscattering. Samples with x=0.18 and 0.32 were heat treated in a vacuum for 60 min at various temperatures up to 320 and 340 °C, respectively. The change of the backscattering spectra with the temperature of heat treatment indicated that the Hg atoms outdiffused partly from the near-surface region of the crystals at higher temperatures than 280 and 320 °C for x=0.18 and 0.32, respectively. This behavior of outdiffusion is in contrast to the case of HgTe crystal.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    UTSUNOMIYA, T. ; YAO, T. ; MASUDA, K. ; TSUNEYOSHI, M.

    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Published 1996
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Recently, the expression of vimentin has been reported in some carcinomas. This study was designed to clarify the significance of vimentin expression in solid type poorly differentiated adenocarcinomas of the stomach. Immunohistochemically, 239 poorly differentiated adenocarcinomas with solid components of the stomach were stained for vimentin. Vimentin-positive cases were also stained by CAM 5.2 using serial mirror sections. We found 15 (6.3%) vimentin-positive cases. Twelve of them demonstrated varying amounts of rhabdoid-like cells. Eight cases diffusely co-expressed vimentin and cytokeratin simultaneously. In addition, four co-expressing cases showed positive staining with Keratin-903 which recognizes the high molecular-weight cytokeratin. Most of the co-expressing cases showed a diffuse proliferation of polygonal tumour cells with focal cell-to-cell contact. The prognosis of the co-expressing cases was poor in comparison with that of the 89 vimentin-negative tumours (P 〈 0.05).
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Maeda, S. ; Ohmori, K. ; Yasuda, N. ; Kurata, K. ; Sakaguchi, M. ; Masuda, K. ; Ohno, K. ; Tsujimoto, H.

    Oxford, UK : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background Since dogs frequently develop allergic diseases, similar to those in humans, dogs represent a possible animal model for allergy in humans. In human atopic dermatitis (AD), CC chemokine receptor 4 (CCR4) has been shown to play an important role in the development of allergic inflammation of AD; however, the association between allergic reaction and CCR4 is not well understood in dogs.Objective To examine CCR4 expression in peripheral blood CD4+ cells in dogs that had AD and were experimentally sensitized with Japanese cedar pollen.Materials and methods Peripheral blood mononuclear cells (PBMCs) were isolated from 17 dogs with AD. The proportion of CCR4+ cells in peripheral blood CD4+ cells (CCR4/CD4) was evaluated by flow cytometry and compared with that in 10 healthy dogs. Similarly, in dogs that were experimentally sensitized to Japanese cedar pollen antigen, the proportion of CCR4/CD4 was examined pre- and post-sensitization.Results The proportion of CCR4/CD4 in dogs with AD was 40.3±3.3%, which was significantly higher than that in normal dogs (23.6±4.3%) (P〈0.01). In the experimentally sensitized dogs, the proportion of CCR4/CD4 was 25.4±2.6% at pre-sensitization and it was significantly increased (29.8±2.9%) at post-sensitization (P〈0.01).Conclusion The proportion of CCR4+ cells in peripheral blood CD4+ cells was measured in dogs with allergic conditions. The present findings indicate that CCR4+ cells may be involved in the pathogenesis of allergy in dogs as in humans.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Watanabe, T ; Oda, Y ; Tamiya, S ; Kinukawa, N ; Masuda, K ; Tsuneyoshi, M

    Oxford UK : Blackwell Science Ltd
    Published 2001
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Malignant peripheral nerve sheath tumours: high Ki67 labelling index is the significant prognostic indicator Aims: We investigated p53, Ki67, MDM2, and p21WAF1/CIP1 in order to evaluate its relationship with prognosis in malignant peripheral nerve sheath tumours (MPNST). Methods and results: In 49 cases of MPNSTs, the immunohistochemical studies of Ki67, p53, MDM2, p21WAF1/CIP1 and polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP) with direct sequencing of p53 were performed with the formalin-fixed paraffin-embedded tissue. In 43 cases with survival data available, an evaluation of the prognostic significance of clinicopathological factors was also carried out. A high Ki67 labelling index (LI) (〉25%) was correlated with a reduced survival rate in the 43 cases of MPNST (P=0.0106, log-rank test). Furthermore, there was a significant correlation between the Ki67 LI and the immunohistochemical expression of p53 or MDM2. In 17 MPNST cases, PCR amplification of exons 5 through 8 of the p53 gene was successful. One case showed a base change of codon 240 (AGT→AGC), but translated amino acid (Ser) remained unchanged. Multivariate Cox analysis of our series showed that the association of von Recklinghausen’s disease, tumour depth, and the presence of rhabdomyoblasts (malignant triton tumour) each had an independent negative impact on overall survival. Conclusion: High Ki67 LI (〉25%) was of significant prognostic value in MPNST.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Miyajima, K ; Oda, Y ; Oshiro, Y ; Tamiya, S ; Kinukawa, N ; Masuda, K ; Tsuneyoshi, M

    Oxford UK : Blackwell Science Ltd
    Published 2002
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Clinicopathological prognostic factors in soft tissue leiomyosarcoma: a multivariate analysis Aims: Prognostic factors affecting survival in cases of leiomyosarcoma of soft parts were investigated in this study. Methods and results: A retrospective study of 267 patients was carried out. This group comprised 142 females (53%) and 125 males (47%), whose ages ranged from 7 to 95 years (median 58 years). One hundred and five cases were superficially situated (arising from the skin or subcutis), while the remaining 162 cases were deeply situated (subfacial). Nineteen were cases of pleomorphic leiomyosarcoma where the diagnosis had been amended from malignant fibrous histiocytoma to leiomyosarcoma whilst under review. Of the 167 patients with follow-up data, 83 died of leiomyosarcoma. In univariate analysis, depth, tumour size (≥50 mm), mitotic rate of 〉20 per 10 high-power fields (HPF), tumour necrosis of 〉50% and a high stage according to the most recent American Joint Committee on Cancer (AJCC) staging for soft tissue sarcoma were found to lessen significantly the rate of survival (log rank test; P 〈 0.05). However, in multivariate analysis (Cox's proportional hazards model), tumour size and high AJCC stage were the only factors that were correlated independently with decreased survival. Conclusions: This study indicates that the most reliable prognostic parameters are tumour size and AJCC stage in leiomyosarcoma.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    1546-1718
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Medicine
    Notes:
    [Auszug] Fukuyama type congenital muscular dystrophy (FCMD) is an autosomal recessive severe muscular dystrophy associated with an anomaly of the brain. Twenty–one FCMD families, 13 of them with consanguineous marriages, were analysed by genetic linkage analyses with polymorphic microsatellite markers ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    MIZOGUCHI, M. ; CHIKAKANE, K. ; GOH, K. ; ASAHINA, Y. ; MASUDA, K.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1987
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    A case of Sweet's syndrome is reported in a patient with Behçlet's disease. This association has not been reported outside Japan. The relationship of the two diseases is discussed.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Morishita, R. ; Masuda, K. ; Niwa, M. ; Kato, K. ; Asano, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Masuda, K. ; Yamada, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0005-2787
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Masuda, K. ; Shirota, H. ; Thonar, E.J.M.A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-2697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    0920-5632
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Akinaga, H. ; Takita, K. ; Asano, H. ; Masuda, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Nakamura, K. ; Masuda, K. ; Mikami, E.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0922-338X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses