Search Results - (Author, Cooperation:K. Maehara)

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  1. 1
    Staff View
    Publication Date:
    2014-09-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Acetylation ; Animals ; Cell Line, Tumor ; Cell Survival ; Chromatin Immunoprecipitation ; Enzyme Activation ; Genome/genetics ; Histones/*chemistry/*metabolism ; Kinetics ; Lysine/metabolism ; Mice ; Microscopy, Fluorescence ; Phosphorylation ; RNA Polymerase II/*metabolism ; *Single-Cell Analysis ; Time Factors ; Transcription Elongation, Genetic ; Transcription Initiation, Genetic ; *Transcription, Genetic
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Kuyama, M. ; Fujimoto, W. ; Kambara, H. ; Egusa, M. ; Saitoh, M. ; Yamasaki, O. ; Maehara, K. ; Ohara, A. ; Arata, J. ; Iwatsuki, K.

    Oxford, UK : Blackwell Science Ltd
    Published 2002
    Staff View
    ISSN:
    1365-2230
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Summary We report two patients with severe amicrobial pustular dermatosis with immunological abnormalities: a 63-year-old woman with a 30-year-history of discoid lupus erythematosus and sicca syndrome, and a 35-year-old woman with high levels of γ-globulinemia and positive antinuclear antibodies. Both patients presented with crusty and eroded erythematous plaques studded with aseptic pustuleson the back, face, and scalp. Histological examination showed acanthosis, neutrophilic exocytosis to the epidermis, and neutrophilic and lymphocytic infiltration with nuclear dust in the dermis. These patients were diagnosed as having ‘amicrobial pustulosis associated with autoimmune diseases’. The eruptions improved with combination treatment of oral prednisolone with cyclosporin A or diaminodiphenylsulphone. Although the pathogenesis remains unclear, amicrobial pustular dermatosis might be one of the cutaneous complications in autoimmune diseases.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2230.2002.01035.x

    Articles: DFG German National Licenses
  3. 3
    Fujita, S. ; Asano, T. ; Maehara, K. ; Tojyo, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-0248
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Geosciences
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0022-0248(94)90899-0

    Articles: DFG German National Licenses
  4. 4
    Okada, K. ; Maehara, K. ; Oda, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-4039
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0040-4039(00)77076-6

    Articles: DFG German National Licenses
  5. 5
    Fujita, S. ; Asano, T. ; Maehara, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0169-4332
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0169-4332(94)90421-9

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    1439-6327
    Keywords:
    Key words Double product/work rate break point  ;   Incremental exercise  ;  Anaerobic threshold  ;  Lactic acidosis threshold
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract A break point in the double product versus work rate relationship (DPBP) during incremental exercise has previously been reported. The aim of the current study was to investigate the frequency and degree of inter-observer agreement with which a DPBP could be detected. We also wished to determine its relationship, if any, to the lactic acidosis threshold␣(LATla). Ten normal volunteers performed continuous incremental bicycle ergometer exercise under three different concentrations of inspired oxygen (F iO2 = 0.21, 0.15 and 0.12). In addition, a group of patients with diseases expected to result in impaired exercise tolerance performed exercise under room air conditions. Gas exchange was measured continuously and double product was measured at 15-s intervals throughout exercise using an automated sphygmomanometer. Four observers, unaware of subject identity and test condition, analysed a total of 39 tests. All four observers detected a DPBP in 29 cases (74%) and an LAT in 35 cases (90%). The intra-class correlation coefficient was 0.76 for the DPBP and 0.93 for the LATla, indicating a reasonable level of agreement among observers for both break points. The DPBP was closely related to the LATla (r = 0.865, P 〈 0.0001), although it occurred at a slightly higher oxygen consumption ( O2, bias 0.137 1 · min−1; 95% confidence intervals 0.041–0.233). We conclude that the DPBP is a common occurrence during incremental exercise. The close relationship between the DPBP and the LATla suggests that both may reflect similar events at the level of the skeletal muscle cell.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004210050120

    Articles: DFG German National Licenses