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1Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
2Latest Papers from Table of Contents or Articles in PressDonnelly, D. J., Smith, R. A., Morin, P., Lipovšek, D., Gokemeijer, J., Cohen, D., Lafont, V., Tran, T., Cole, E. L., Wright, M., Kim, J., Pena, A., Kukral, D., Dischino, D. D., Chow, P., Gan, J., Adelakun, O., Wang, X.-T., Cao, K., Leung, D., Bonacorsi, S. J., Hayes, W.
The Society of Nuclear Medicine (SNM)
Published 2018Staff ViewPublication Date: 2018-03-06Publisher: The Society of Nuclear Medicine (SNM)Print ISSN: 0022-3123Topics: MedicinePublished by: -
3Latest Papers from Table of Contents or Articles in PressHong-Jin Zhao; Christian Klausen; Yan Li; Hua Zhu; Yan-Ling Wang; Peter C. K. Leung
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-02-08Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-4889Topics: BiologyMedicinePublished by: -
4Latest Papers from Table of Contents or Articles in PressAnggara, K., Leung, L., Timm, M. J., Hu, Z., Polanyi, J. C.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-10-06Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
5Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-06-23Publisher: American Physical Society (APS)Print ISSN: 1050-2947Electronic ISSN: 1094-1622Topics: PhysicsKeywords: Atomic and molecular collisions and interactionsPublished by: -
6Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2011-04-26Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Binding Sites ; Crystallography, X-Ray ; Humans ; Models, Molecular ; Nucleotides/chemistry/metabolism ; Protein Folding ; Protein Structure, Tertiary ; RNA/chemistry/metabolism ; Ribonucleoprotein, U1 Small Nuclear/chemistry ; Ribonucleoprotein, U4-U6 Small Nuclear/*biosynthesis/*chemistry/metabolism ; Spliceosomes/chemistry/metabolism ; Structure-Activity RelationshipPublished by: -
7Latest Papers from Table of Contents or Articles in PressH. B. Li ; K. H. Yuen ; F. Otto ; P. K. Leung ; T. K. Sridharan ; Q. Zhang ; H. Liu ; Y. W. Tang ; K. Qiu
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-03-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
8Latest Papers from Table of Contents or Articles in PressP. Eirew ; A. Steif ; J. Khattra ; G. Ha ; D. Yap ; H. Farahani ; K. Gelmon ; S. Chia ; C. Mar ; A. Wan ; E. Laks ; J. Biele ; K. Shumansky ; J. Rosner ; A. McPherson ; C. Nielsen ; A. J. Roth ; C. Lefebvre ; A. Bashashati ; C. de Souza ; C. Siu ; R. Aniba ; J. Brimhall ; A. Oloumi ; T. Osako ; A. Bruna ; J. L. Sandoval ; T. Algara ; W. Greenwood ; K. Leung ; H. Cheng ; H. Xue ; Y. Wang ; D. Lin ; A. J. Mungall ; R. Moore ; Y. Zhao ; J. Lorette ; L. Nguyen ; D. Huntsman ; C. J. Eaves ; C. Hansen ; M. A. Marra ; C. Caldas ; S. P. Shah ; S. Aparicio
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-12-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Breast Neoplasms/*genetics/*pathology/secondary ; Clone Cells/*metabolism/*pathology ; DNA Mutational Analysis ; Genome, Human/*genetics ; Genomics ; Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; Mice ; Neoplasm Transplantation ; *Single-Cell Analysis ; Time Factors ; Transplantation, Heterologous ; *Xenograft Model Antitumor Assays/methodsPublished by: -
9Latest Papers from Table of Contents or Articles in PressK. Howe ; M. D. Clark ; C. F. Torroja ; J. Torrance ; C. Berthelot ; M. Muffato ; J. E. Collins ; S. Humphray ; K. McLaren ; L. Matthews ; S. McLaren ; I. Sealy ; M. Caccamo ; C. Churcher ; C. Scott ; J. C. Barrett ; R. Koch ; G. J. Rauch ; S. White ; W. Chow ; B. Kilian ; L. T. Quintais ; J. A. Guerra-Assuncao ; Y. Zhou ; Y. Gu ; J. Yen ; J. H. Vogel ; T. Eyre ; S. Redmond ; R. Banerjee ; J. Chi ; B. Fu ; E. Langley ; S. F. Maguire ; G. K. Laird ; D. Lloyd ; E. Kenyon ; S. Donaldson ; H. Sehra ; J. Almeida-King ; J. Loveland ; S. Trevanion ; M. Jones ; M. Quail ; D. Willey ; A. Hunt ; J. Burton ; S. Sims ; K. McLay ; B. Plumb ; J. Davis ; C. Clee ; K. Oliver ; R. Clark ; C. Riddle ; D. Elliot ; G. Threadgold ; G. Harden ; D. Ware ; S. Begum ; B. Mortimore ; G. Kerry ; P. Heath ; B. Phillimore ; A. Tracey ; N. Corby ; M. Dunn ; C. Johnson ; J. Wood ; S. Clark ; S. Pelan ; G. Griffiths ; M. Smith ; R. Glithero ; P. Howden ; N. Barker ; C. Lloyd ; C. Stevens ; J. Harley ; K. Holt ; G. Panagiotidis ; J. Lovell ; H. Beasley ; C. Henderson ; D. Gordon ; K. Auger ; D. Wright ; J. Collins ; C. Raisen ; L. Dyer ; K. Leung ; L. Robertson ; K. Ambridge ; D. Leongamornlert ; S. McGuire ; R. Gilderthorp ; C. Griffiths ; D. Manthravadi ; S. Nichol ; G. Barker ; S. Whitehead ; M. Kay ; J. Brown ; C. Murnane ; E. Gray ; M. Humphries ; N. Sycamore ; D. Barker ; D. Saunders ; J. Wallis ; A. Babbage ; S. Hammond ; M. Mashreghi-Mohammadi ; L. Barr ; S. Martin ; P. Wray ; A. Ellington ; N. Matthews ; M. Ellwood ; R. Woodmansey ; G. Clark ; J. Cooper ; A. Tromans ; D. Grafham ; C. Skuce ; R. Pandian ; R. Andrews ; E. Harrison ; A. Kimberley ; J. Garnett ; N. Fosker ; R. Hall ; P. Garner ; D. Kelly ; C. Bird ; S. Palmer ; I. Gehring ; A. Berger ; C. M. Dooley ; Z. Ersan-Urun ; C. Eser ; H. Geiger ; M. Geisler ; L. Karotki ; A. Kirn ; J. Konantz ; M. Konantz ; M. Oberlander ; S. Rudolph-Geiger ; M. Teucke ; C. Lanz ; G. Raddatz ; K. Osoegawa ; B. Zhu ; A. Rapp ; S. Widaa ; C. Langford ; F. Yang ; S. C. Schuster ; N. P. Carter ; J. Harrow ; Z. Ning ; J. Herrero ; S. M. Searle ; A. Enright ; R. Geisler ; R. H. Plasterk ; C. Lee ; M. Westerfield ; P. J. de Jong ; L. I. Zon ; J. H. Postlethwait ; C. Nusslein-Volhard ; T. J. Hubbard ; H. Roest Crollius ; J. Rogers ; D. L. Stemple
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-04-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Chromosomes/genetics ; Conserved Sequence/*genetics ; Evolution, Molecular ; Female ; Genes/genetics ; Genome/*genetics ; Genome, Human/genetics ; Genomics ; Humans ; Male ; Meiosis/genetics ; Molecular Sequence Annotation ; Pseudogenes/genetics ; Reference Standards ; Sex Determination Processes/genetics ; Zebrafish/*genetics ; Zebrafish Proteins/geneticsPublished by: -
10Latest Papers from Table of Contents or Articles in PressChung, V. C. H., Wong, C. H. L., Ching, J. Y. L., Sun, W. Z., Ju, Y. L., Hung, S. S., Lin, W. L., Leung, K. C., Wong, S. Y. S., Wu, J. C. Y.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-03-29Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Complementary medicinePublished by: -
11Articles: DFG German National Licensesvan Os, C. F. A. ; Leung, K. N. ; Kunkel, W. B.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The production of H− ions at a barium, magnesium, strontium, molybdenum, and lanthanum-hexaboride converter immersed in a hydrogen plasma have been investigated for pulsed and dc discharges. The scaling of the negative-ion output with incident positive-ion current on the converter depends greatly on the actual geometry and type of plasma generator. A less than linear scaling is observed in a multicusp system using filaments or rf to generate the discharge. A more than linear scaling is obtained in a configuration where the filament and the converter are separated by a permanent-magnet filter. For a rf plasma generator, there is a pronounced optimum in the relative position of antenna and converter.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesGorunganthu, R. R. ; Coplan, M. A. ; Leung, K. T. ; Tossell, J. A. ; Moore, J. H.
College Park, Md. : American Institute of Physics (AIP)
Published 1989Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The distribution of electron momentum density has been measured for the outermost occupied orbitals of the vinyl halides and ethylene using the (e,2e) technique. In contrast to the ionization potentials for these π orbitals which decrease monotonically from vinyl fluoride to vinyl iodide, the values of the momenta where the distributions are a maximum, pmax, increase from the fluoride through the bromide and then shift back to a lower value for the iodide. This observation can be analyzed in terms of B(r), the Fourier transform of the observed momentum distribution, and ΔB(r), the difference between B(r) functions. The shape of ΔB(r) for the fluoride, chloride, and bromide in comparison to ethylene reflects the effect of the carbon–halogen antibonding interaction in these vinyl halides. On the other hand, in vinyl iodide the antibonding interaction is compensated for by the diffuse iodine 5p character of the molecular orbital. The relation of these observations to chemical properties of the vinyl halides is discussed along with differences between experiment and calculations at low momentum.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesYing, J. F. ; Daniels, T. A. ; Mathers, C. P. ; Zhu, H. ; Leung, K. T.
College Park, Md. : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: A coplanar electron spectrometer has been constructed for angle-resolved electron energy loss measurements. The experimental arrangement and performance of the spectrometer are described. Absolute absorption transition probabilities (or generalized oscillator strengths) of valence-shell (7–70 eV) electronic transitions of SF6 have been determined as a function of energy loss and momentum transfer at an impact energy of 2.5 keV. New nondipole transitions have been observed at nonzero momentum transfer. Together with the term values obtained from previous dipole electron energy loss and photoabsorption measurements, the momentum transfer dependence of the transition probabilities can be used to provide tentative assignments of the observed nondipole valence-shell transitions of SF6. Despite the complexity of the electronic structure of SF6, the present work demonstrates the feasibility of angle-resolved electron energy loss spectroscopy for investigating nondipole phenomena and related electron-induced excitation processes.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesYing, J. F. ; Zhu, H. ; Mathers, C. P. ; Gover, B. N. ; Banjavcic, M. P. ; Zheng, Y. ; Brion, C. E. ; Leung, K. T.
College Park, Md. : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Electron-momentum-specific ionization energy (IE) spectra of cis-, trans-, and iso-butene were obtained from 8 to 44 eV ionization energy using noncoplanar symmetric (e,2e) spectroscopy and compared with the corresponding photoelectron spectra obtained using monochromated synchrotron radiation at 100 eV photon energy. In the independent particle picture, the intensity variation of a particular ionic state as a function of the electron momentum in an (e,2e) IE spectrum is characteristic of electron momentum density of the ionized orbital. Under favorable conditions, the (e,2e) IE spectra measured at two relative azimuthal angles (0° and 8°) can be used to provide a unique characterization of the dominant orbital composition of a particular ionic state. Together with ab initio calculations, these spectra have been used to clarify the nature of some of the ionic states found in the photoelectron spectroscopic studies. In particular, the presence of prominent many-body structures in the inner-valence region (≥20 eV) for all three butene isomers indicates the general breakdown of Koopmans' ionization picture in this region. The nature of these many-body states is inferred from their electron momentum dependence in the (e,2e) IE spectra and from recently published configuration-interaction calculations.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: In cooperation with the Lawrence Berkeley Laboratory, a multicusp ion source has been investigated. The goal of these investigations is to generate a nearly pure atomic nitrogen (N+) ion beam. To achieve this, the discharge chamber is divided into two parts of different plasma parameters by means of a filter magnetic field. As beam diagnostics, a bending magnet and a faraday cup have been used. Measurements of the beam current density and the ion composition for a wide range of discharge conditions have been performed. By using a Langmuir probe, we have performed measurements of electron temperature and electron density.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesKwan, J. W. ; Anderson, O. A. ; Chan, C. F. ; Cooper, W. S. ; deVries, G. J. ; Kunkel, W. B. ; Leung, K. N. ; Lietzke, A. F. ; Steele, W. F. ; van Os, C. F. A. ; Wells, R. P. ; Williams, M. D.
[S.l.] : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: A D− surface-conversion source using a solid barium converter is designed for steady-state operation to produce 200 mA of D−. A similar ion source of twice the size as the one discussed here will meet the requirements set by the present US-ITER neutral beam injector design. Among the possible types of ion sources being considered for the US-ITER neutral beam design, the barium converter surface-conversion source is the only kind that does not use cesium in the discharge. This absence of cesium will minimize the number of accelerator breakdowns.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesYoung, A. T. ; Stutzin, G. C. ; Chen, P. ; Kunkel, W. B. ; Leung, K. N.
[S.l.] : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The populations of ground electronic state atomic hydrogen and ground electronic state, vibrationally–rotationally excited hydrogen molecule in a negative hydrogen ion source discharge have been measured using vacuum ultraviolet (VUV) laser absorption spectroscopy. These populations have been measured under a variety of discharge conditions in two different regions of a tandem chamber ion source. Preliminary results of the measurements in the driver region and filter region are given. It is observed that the atomic hydrogen density decreases as one goes from the driver to the filter region. This indicates that the surfaces directly adjacent to the filter region are net sinks for hydrogen atoms. In contrast, the molecular vibrational population distribution shows only a small difference between the two regions, indicating that these surfaces are not net sinks for the excited molecules.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesLeung, K. N. ; DeVries, G. J. ; DiVergilio, W. F. ; Hamm, R. W. ; Hauck, C. A. ; Kunkel, W. B. ; McDonald, D. S. ; Williams, M. D.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: An rf driven multicusp source capable of generating 1-ms H− beam pulses with a repetition rate as high as 150 Hz has been developed. This source can be operated with a filament or other types of starter. There is almost no lifetime limitation and a clean plasma can be maintained for a long period of operation. It is demonstrated that rf power as high as 25 kW could be coupled inductively to the plasma via a glass-coated copper-coil antenna. The extracted H− current density achieved is about 200 mA/cm2.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: For the injection of a low-current (100 μA) high-brightness ion beam into an EBIS for subsequent ionization to very high-charge states, we have constructed a bucket-type ion source with the following specific features: a) microwave discharge plasma generator for long lifetime, b) isolated end flanges to allow for versatile ion species production by sputtering, c) SmCo magnets in 90° easy-axis rotation for the magnetic cusp fields, and d) large diameter for reduction of gas load to the UHV beamline of the EBIS. The extraction system has been optimized for maximum brilliance at an emission current density of about 2 mA/cm2. The extraction electrode consists of a spent washer of the sputtered material and of the long-lasting complex shaped main part. The design provides almost unchanged extraction optics until the washer is sputtered away.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesKwan, J. W. ; Ackerman, G. D. ; Anderson, O. A. ; Chan, C. F. ; Cooper, W. S. ; deVries, G. J. ; Kunkel, W. B. ; Leung, K. N. ; Purgalis, P. ; Steele, W. F. ; Wells, R. P.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: In testing a cesiated volume-production negative ion source, we have obtained 75 mA of H− beam current in a 270 ms pulse length delivered downstream of the 87 keV preaccelerator. Optimum pressure in the source was less than 8 mT and the electron-to-ion ratio in the beam was less than 4. With future improvements in the electron trap, it is anticipated that higher H− current can be obtained by operating with a higher discharge power and a lower plasma electrode bias.Type of Medium: Electronic ResourceURL: