Search Results - (Author, Cooperation:K. J. Morris)

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    E. Arner ; C. O. Daub ; K. Vitting-Seerup ; R. Andersson ; B. Lilje ; F. Drablos ; A. Lennartsson ; M. Ronnerblad ; O. Hrydziuszko ; M. Vitezic ; T. C. Freeman ; A. M. Alhendi ; P. Arner ; R. Axton ; J. K. Baillie ; A. Beckhouse ; B. Bodega ; J. Briggs ; F. Brombacher ; M. Davis ; M. Detmar ; A. Ehrlund ; M. Endoh ; A. Eslami ; M. Fagiolini ; L. Fairbairn ; G. J. Faulkner ; C. Ferrai ; M. E. Fisher ; L. Forrester ; D. Goldowitz ; R. Guler ; T. Ha ; M. Hara ; M. Herlyn ; T. Ikawa ; C. Kai ; H. Kawamoto ; L. M. Khachigian ; S. P. Klinken ; S. Kojima ; H. Koseki ; S. Klein ; N. Mejhert ; K. Miyaguchi ; Y. Mizuno ; M. Morimoto ; K. J. Morris ; C. Mummery ; Y. Nakachi ; S. Ogishima ; M. Okada-Hatakeyama ; Y. Okazaki ; V. Orlando ; D. Ovchinnikov ; R. Passier ; M. Patrikakis ; A. Pombo ; X. Y. Qin ; S. Roy ; H. Sato ; S. Savvi ; A. Saxena ; A. Schwegmann ; D. Sugiyama ; R. Swoboda ; H. Tanaka ; A. Tomoiu ; L. N. Winteringham ; E. Wolvetang ; C. Yanagi-Mizuochi ; M. Yoneda ; S. Zabierowski ; P. Zhang ; I. Abugessaisa ; N. Bertin ; A. D. Diehl ; S. Fukuda ; M. Furuno ; J. Harshbarger ; A. Hasegawa ; F. Hori ; S. Ishikawa-Kato ; Y. Ishizu ; M. Itoh ; T. Kawashima ; M. Kojima ; N. Kondo ; M. Lizio ; T. F. Meehan ; C. J. Mungall ; M. Murata ; H. Nishiyori-Sueki ; S. Sahin ; S. Nagao-Sato ; J. Severin ; M. J. de Hoon ; J. Kawai ; T. Kasukawa ; T. Lassmann ; H. Suzuki ; H. Kawaji ; K. M. Summers ; C. Wells ; D. A. Hume ; A. R. Forrest ; A. Sandelin ; P. Carninci ; Y. Hayashizaki
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-02-14
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Binding Sites ; Cattle ; Cell Differentiation/*genetics ; Dogs ; *Enhancer Elements, Genetic ; *Gene Expression Regulation, Developmental ; Mice ; RNA, Messenger/genetics/metabolism ; Rats ; Stem Cells/*cytology/metabolism ; Transcription Factors/*metabolism ; *Transcription, Genetic
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Morris, K. J. ; Townsend, K. M. S. ; Batchelor, A. L.
    Springer
    Published 1989
    Staff View
    ISSN:
    1432-2099
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Physics
    Notes:
    Summary Seventy-three rats were exposed to an aerosol of enriched uranium dioxide (UO2), giving initial lung burdens of 26 to 447 µg at 6 days post-inhalation (PI). At 7 days PI 35 of these rats were further exposed to thermalised neutrons at a fluence of 1 x 1012 neutrons CM−2. There was no significant difference between the two groups in the clearance rate of the UO2 particles from the lung, up to 590 days PI. The particles cleared relatively slowly over this period with a retention halftime in the lung of 160 to 176 days. Transmission electron microscope (TEM) studies of tissue from the alveolar region at 8 days PI showed that inhalation of UO2 particles significantly increased the sizes of macrophage and type II cells, and the number of macrophage and type I cells. There was also a significant increase in the size of lysosomal granules within the macrophages after exposure to the UO2 particles. The exposure to UO2, neutrons and235U fission fragments had no significant effect on any of the cells above that observed in the animals exposed to UO2 alone. Additional rats were exposed to the same neutron fluence without prior UO2 inhalation. The alveolar cells of neutron-only exposed rats were, in size and number, typically no different from those in the completely unexposed control rats.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01210298

    Articles: DFG German National Licenses