Search Results - (Author, Cooperation:K. Howard)

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    Staff View
    Publication Date:
    2011-09-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Aging/genetics/physiology ; Animals ; Animals, Genetically Modified ; Caenorhabditis elegans/genetics/metabolism/*physiology ; Caenorhabditis elegans Proteins/*genetics/metabolism ; Caloric Restriction ; Crosses, Genetic ; Drosophila Proteins/*genetics/metabolism ; Drosophila melanogaster/genetics/metabolism/*physiology ; Female ; Gene Expression ; Histone Deacetylases/*genetics/metabolism ; Longevity/genetics/*physiology ; Male ; RNA, Messenger/analysis/genetics ; Sirtuins/*genetics/metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
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    STEINMAN, HOWARD K. ; PAPPENFORT, ROBERT B.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1984
    Staff View
    ISSN:
    1365-2230
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    White piedra (trichosporosis) is an unusual fungal infection of hair characterised by the presence of numerous, discrete, soft, asymptomatic nodules attached to the infected hair shafts. It may occur on the scalp, eyebrows, eyelashes, beard, axilla, or in the groin (Smith, Murtishaw & McBride, 1973; Taplin & Rebell, 1979a), although most infections occur on the face or scalp (Smith et al., 1973). Caused by the yeast-like fungus Trichosporon beigelii, white piedra was first described in London (Beigel, 1865), and has since been reported in Europe, North and South America, and Asia (Scott, 1951; Benson, Lapins & Odom, 1983). Successful treatment of white piedra has been achieved with simple hair clipping and with the use of various topical medications. To our knowledge, there have been no reports of successful treatment with the use of topically applied imidazole preparations. We report a case of white piedra confined to the scrotum that responded to topical clotrimazole lotion.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
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    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Diamondlike carbon (DLC) films were prepared by high-intensity pulsed-ion-beam ablation of graphite targets. A 350 keV, 35 kA, 400 ns beam, consisting primarily of hydrogen, carbon, and oxygen ions was focused onto a graphite target at a fluence of 15–45 J/cm2. Amorphous carbon films were deposited at up to 30 nm per pulse, corresponding to an instantaneous deposition rate greater than 1 mm/s. Electrical resistivities were between 1 and 1000 Ω cm. Raman spectra indicate that diamondlike carbon is present in most of the films. Electron-energy-loss spectroscopy indicates significant amounts of sp3-bonded carbon, consistent with the presence of DLC. Scanning electron microscopy showed most films contain 100 nm features, but micron size particles were deposited as well. Initial tests revealed favorable electron field-emission behavior.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Suzuki, Howard K.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1963
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    GERSHENFELD, HOWARD K. ; HERSHBERGER, R. JANE ; MUELLER, CHRISTOPH ; WEISSMAN, IRVING L.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1988
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Mueller, Christoph ; Rshenfeld, Howard K. ; Weisman, Irving L.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1988
    Staff View
    ISSN:
    1600-065X
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Steinman, Howard K. ; Lovell, Christopher R. ; Cronin, Etain

    Oxford, UK : Blackwell Publishing Ltd
    Published 1984
    Staff View
    ISSN:
    1600-0536
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Miyakawa, Hiroshi ; Honma, Kiyonobu ; Qi, Mingshan ; Kuramitsu, Howard K.

    Oxford, UK : Munksgaard International Publishers
    Published 2004
    Staff View
    ISSN:
    1600-0765
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Objective:  The association of periodontitis with atherosclerosis has been suggested from epidemiological studies. Recently, we have reported that macrophages stimulated by Porphyromonas gingivalis formed foam cells in the presence of low-density lipoproteins (LDL). In this study, we examined the direct interactions between LDL and P. gingivalis.Methods:  We investigated the aggregation of LDL with P. gingivalis and its outer membrane vesicles (OMVs), degradation of the apo B-100 protein of LDL by sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS–PAGE) and western blot analyses, as well as the effects of protease inhibitors or activators on the mobility of LDL by agarose gel shift assays. The binding of P. gingivalis or its OMVs with LDL was demonstrated by western blot analysis. We also examined whether or not the aggregated LDL induced foam cell formation from murine macrophages.Results:  LDL was aggregated in a dose-dependent manner with P. gingivalis and its OMVs. Moreover, degradation of the apo B-100 protein of LDL was directly demonstrated in the presence of P. gingivalis or its OMVs. Furthermore, the gel shift assays indicated that the mobility of LDL was increased in the presence of P. gingivalis. This alteration was attenuated in the presence of the protease inhibitors TLCK and leupeptin and increased in the presence of reducing agents. Moreover, LDL was bound to specific proteins of P. gingivalis suggesting that these proteins may also play a role in aggregation. Finally, the aggregated LDL induced murine macrophages to form foam cells.Conclusions:  These results suggest that P. gingivalis may stimulate foam cell formation, in part, by aggregating LDL by proteolysis of apo B-100.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
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    WORNER, HOWARD K.

    [s.l.] : Nature Publishing Group
    Published 1962
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] PRACTICALLY every steel-making plant in JT the world, has greatly increased its output in recent years. Some of this increase has resulted from improvements in technique and efficiency of operation, but in other cases it has been mainly due to the building of more or bigger ovens, furnaces and ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    BEALE, HOWARD K.

    New York, N.Y. : Periodicals Archive Online (PAO)
    Published 1934
    Articles: DFG German National Licenses
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    Howard, K. ; Donlon, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0020-711X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
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    Staff View
    ISSN:
    0021-8634
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    O'Sullivan, M.A. ; Howard, K. ; Sueoka, N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-2836
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Hayashi, Jun-ichiro ; Hamada, Nobushiro ; Kuramitsu, Howard K

    Oxford, UK : Blackwell Publishing Ltd
    Published 2002
    Staff View
    ISSN:
    1574-6968
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    An autolysin mutant of Porphyromonas gingivalis was constructed and its outer membrane vesicle production was compared to that of wild-type strain 381. The autolysin mutant produced elevated levels of vesicles relative to the parental strain. It is suggested that vesicle formation of this organism may be regulated by cell wall turnover.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses