Search Results - (Author, Cooperation:K. Howard)
-
1Ahmadvand, A., Drennan, J., Burgess, J., Clark, M., Kavanagh, D., Burns, K., Howard, S., Kelly, F., Campbell, C., Nissen, L., Curtis, Porter, Porter, Kaye, Duguay
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-04-29Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Health services research, IT, TelemedicinePublished by: -
2C. Burnett ; S. Valentini ; F. Cabreiro ; M. Goss ; M. Somogyvari ; M. D. Piper ; M. Hoddinott ; G. L. Sutphin ; V. Leko ; J. J. McElwee ; R. P. Vazquez-Manrique ; A. M. Orfila ; D. Ackerman ; C. Au ; G. Vinti ; M. Riesen ; K. Howard ; C. Neri ; A. Bedalov ; M. Kaeberlein ; C. Soti ; L. Partridge ; D. Gems
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-09-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aging/genetics/physiology ; Animals ; Animals, Genetically Modified ; Caenorhabditis elegans/genetics/metabolism/*physiology ; Caenorhabditis elegans Proteins/*genetics/metabolism ; Caloric Restriction ; Crosses, Genetic ; Drosophila Proteins/*genetics/metabolism ; Drosophila melanogaster/genetics/metabolism/*physiology ; Female ; Gene Expression ; Histone Deacetylases/*genetics/metabolism ; Longevity/genetics/*physiology ; Male ; RNA, Messenger/analysis/genetics ; Sirtuins/*genetics/metabolismPublished by: -
3Staff View
Publication Date: 2018-04-20Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Health policy, Clinical trials (epidemiology), Open access, Health services researchPublished by: -
4Staff View
ISSN: 1365-2230Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: White piedra (trichosporosis) is an unusual fungal infection of hair characterised by the presence of numerous, discrete, soft, asymptomatic nodules attached to the infected hair shafts. It may occur on the scalp, eyebrows, eyelashes, beard, axilla, or in the groin (Smith, Murtishaw & McBride, 1973; Taplin & Rebell, 1979a), although most infections occur on the face or scalp (Smith et al., 1973). Caused by the yeast-like fungus Trichosporon beigelii, white piedra was first described in London (Beigel, 1865), and has since been reported in Europe, North and South America, and Asia (Scott, 1951; Benson, Lapins & Odom, 1983). Successful treatment of white piedra has been achieved with simple hair clipping and with the use of various topical medications. To our knowledge, there have been no reports of successful treatment with the use of topically applied imidazole preparations. We report a case of white piedra confined to the scrotum that responded to topical clotrimazole lotion.Type of Medium: Electronic ResourceURL: -
5Johnston, Gregory P. ; Tiwari, Prabhat ; Rej, Donald J. ; Davis, Harold A. ; Waganaar, William J. ; Muenchausen, Ross E. ; Walter, Kevin C. ; Nastasi, Michael ; Schmidt, Howard K. ; Kumar, Nalin ; Lin, Boyang ; Tallant, David R. ; Simpson, Regina L. ; Williams, David B. ; Qiu, Xiamei
[S.l.] : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Diamondlike carbon (DLC) films were prepared by high-intensity pulsed-ion-beam ablation of graphite targets. A 350 keV, 35 kA, 400 ns beam, consisting primarily of hydrogen, carbon, and oxygen ions was focused onto a graphite target at a fluence of 15–45 J/cm2. Amorphous carbon films were deposited at up to 30 nm per pulse, corresponding to an instantaneous deposition rate greater than 1 mm/s. Electrical resistivities were between 1 and 1000 Ω cm. Raman spectra indicate that diamondlike carbon is present in most of the films. Electron-energy-loss spectroscopy indicates significant amounts of sp3-bonded carbon, consistent with the presence of DLC. Scanning electron microscopy showed most films contain 100 nm features, but micron size particles were deposited as well. Initial tests revealed favorable electron field-emission behavior.Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
7GERSHENFELD, HOWARD K. ; HERSHBERGER, R. JANE ; MUELLER, CHRISTOPH ; WEISSMAN, IRVING L.
Oxford, UK : Blackwell Publishing Ltd
Published 1988Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
8Mueller, Christoph ; Rshenfeld, Howard K. ; Weisman, Irving L.
Oxford, UK : Blackwell Publishing Ltd
Published 1988Staff ViewISSN: 1600-065XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
9Steinman, Howard K. ; Lovell, Christopher R. ; Cronin, Etain
Oxford, UK : Blackwell Publishing Ltd
Published 1984Staff ViewISSN: 1600-0536Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
10Miyakawa, Hiroshi ; Honma, Kiyonobu ; Qi, Mingshan ; Kuramitsu, Howard K.
Oxford, UK : Munksgaard International Publishers
Published 2004Staff ViewISSN: 1600-0765Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Objective: The association of periodontitis with atherosclerosis has been suggested from epidemiological studies. Recently, we have reported that macrophages stimulated by Porphyromonas gingivalis formed foam cells in the presence of low-density lipoproteins (LDL). In this study, we examined the direct interactions between LDL and P. gingivalis.Methods: We investigated the aggregation of LDL with P. gingivalis and its outer membrane vesicles (OMVs), degradation of the apo B-100 protein of LDL by sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS–PAGE) and western blot analyses, as well as the effects of protease inhibitors or activators on the mobility of LDL by agarose gel shift assays. The binding of P. gingivalis or its OMVs with LDL was demonstrated by western blot analysis. We also examined whether or not the aggregated LDL induced foam cell formation from murine macrophages.Results: LDL was aggregated in a dose-dependent manner with P. gingivalis and its OMVs. Moreover, degradation of the apo B-100 protein of LDL was directly demonstrated in the presence of P. gingivalis or its OMVs. Furthermore, the gel shift assays indicated that the mobility of LDL was increased in the presence of P. gingivalis. This alteration was attenuated in the presence of the protease inhibitors TLCK and leupeptin and increased in the presence of reducing agents. Moreover, LDL was bound to specific proteins of P. gingivalis suggesting that these proteins may also play a role in aggregation. Finally, the aggregated LDL induced murine macrophages to form foam cells.Conclusions: These results suggest that P. gingivalis may stimulate foam cell formation, in part, by aggregating LDL by proteolysis of apo B-100.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0021-3020Topics: Romance StudiesURL: -
12Staff View
ISSN: 0022-0973Topics: EducationURL: -
13Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] PRACTICALLY every steel-making plant in JT the world, has greatly increased its output in recent years. Some of this increase has resulted from improvements in technique and efficiency of operation, but in other cases it has been mainly due to the building of more or bigger ovens, furnaces and ...Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0017-789XTopics: General, InterdisciplinaryURL: -
15Staff View
ISSN: 0010-4124Topics: Linguistics and Literary StudiesNotes: REVIEWSURL: -
16Staff View
ISSN: 0018-2370Topics: HistoryURL: -
17Staff View
ISSN: 0020-711XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0021-8634Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0022-2836Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
20Hayashi, Jun-ichiro ; Hamada, Nobushiro ; Kuramitsu, Howard K
Oxford, UK : Blackwell Publishing Ltd
Published 2002Staff ViewISSN: 1574-6968Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: An autolysin mutant of Porphyromonas gingivalis was constructed and its outer membrane vesicle production was compared to that of wild-type strain 381. The autolysin mutant produced elevated levels of vesicles relative to the parental strain. It is suggested that vesicle formation of this organism may be regulated by cell wall turnover.Type of Medium: Electronic ResourceURL: