Search Results - (Author, Cooperation:K. Hotta)

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  1. 1
    K. Hotta ; X. Chen ; R. S. Paton ; A. Minami ; H. Li ; K. Swaminathan ; Mathews, II ; K. Watanabe ; H. Oikawa ; K. N. Houk ; C. Y. Kim
    Nature Publishing Group (NPG)
    Published 2012
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    Publication Date:
    2012-03-06
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Biocatalysis ; Biological Products/chemistry/metabolism ; Crystallography, X-Ray ; Cyclization ; Epoxide Hydrolases/*chemistry/genetics/*metabolism ; Ethers/*chemistry/*metabolism ; Hydrogen Bonding ; Lasalocid/analogs & derivatives/*biosynthesis/*chemistry/metabolism ; Models, Molecular ; Molecular Structure ; Protein Conformation ; Streptomyces/genetics ; Structure-Activity Relationship
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Ikeda, H. ; Hotta, K. ; Yamada, T. ; Zaima, S. ; Iwano, H. ; Yasuda, Y.

    [S.l.] : American Institute of Physics (AIP)
    Published 1995
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The adsorption of oxygen on H-terminated Si(100) surfaces has been investigated by high-resolution electron energy loss spectroscopy (HREELS). Adsorptions of atomic oxygen occur even at room temperature. Si-OH stretching and Si-O-Si (B1) vibrational modes are observed in HREELS spectra, which indicates that atomic oxygen is adsorbed on sites of Si—H bonds and Si—Si back bonds. On the other hand, H-terminated surfaces are very stable for molecular oxygen, which cannot adsorb until 380 °C on the surface. A dissociative adsorption of molecular oxygen is observed above 380 °C and the activation energy of the adsorption is 2.0 eV at 380–450 °C. This value coincides with the desorption energy of hydrogen atoms from a Si(100) surface with the monohydride phase. These results indicate that the dangling bonds are essential to the adsorption of molecular oxygen on Si(100) surfaces. © 1995 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.359323

    Articles: DFG German National Licenses
  3. 3
    Sera, K. ; Okumura, F. ; Kaneko, S. ; Itoh, S. ; Hotta, K. ; Hoshino, H.

    [S.l.] : American Institute of Physics (AIP)
    Published 1990
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The fabrication of n+ and p+ silicon thin film by using a combination of "spin-on-glass'' and XeCl excimer-laser doping is described. The doping can be achieved by rapid dopant atom diffusion into molten silicon from a spin-coated film containing the dopant. This technology offers the advantages of process simplicity, low processing temperature, and ultrashallow high-concentration doping. The obtained sheet resistances (2 kΩ/(D'Alembertian) for n+ and 9 kΩ/(D'Alembertian) for p+) are acceptable for thin-film transistors (TFTs). The energy required for doping into a thin film was less than half of that for a silicon wafer. This is mainly due to the absorption rate difference between noncrystalline and crystalline silicon. This process appears extremely promising for TFT fabrication.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.345531

    Articles: DFG German National Licenses
  4. 4
    Hotta, K. ; Goso, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-2697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-2697(81)90200-1

    Articles: DFG German National Licenses
  5. 5
    Sano, T ; Hiki, Y ; Kokubo, T ; Iwase, H ; Hotta, K ; Masaki, Y ; Tanaka, A ; Hisatani, K ; Shigematsu, H ; Kobayashi, Y

    Melbourne, Australia : Blackwell Science Asia Pty. Ltd.
    Published 1999
    Staff View
    ISSN:
    1440-1797
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1440-1797.1999.00088.x

    Articles: DFG German National Licenses
  6. 6
    Wang, Y-Z ; Mitomi, H ; Kurihara, M ; Ishihara, K ; Hotta, K ; Tanigawa, H ; Okayasu, I

    Oxford, UK : Blackwell Science Ltd
    Published 2000
    Staff View
    ISSN:
    1365-2559
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    AimsTo investigate the histogenetic relationship between gastric epithelial neoplasms we studied differences in expression of mucin carbohydrate antigens and mucin core protein, in normal and metaplastic gastric mucosa, and in gastric adenomas and superficial adenocarcinomas.Methods and resultsWe generated four monoclonal antibodies, including HGM72/75 against human gastric mucin and HCM14/21 against human colonic mucin, and investigated immunoreactivities of these antibodies and MUC2 protein expression in normal and metaplastic gastric mucosa, adenomas (15 samples) and superficial adenocarcinomas (intestinal-type, 77; diffuse-type, 59 samples). HGM72 reacted with mucous neck cells of the fundic glands and with pyloric glandular cells whereas HGM75 stained foveolar cells and metaplastic goblet cells. Weak binding of HCM14/21 and strong staining with MUC2 were found in metaplastic goblet cells. Binding of HGM75, HCM14, MUC2, but not HGM72 was high in adenomas. An equivalent staining with HGM72 and HGM75 with low expression of MUC2 and HCM14 was shown in intestinal-type carcinomas while the diffuse-type demonstrated more strong reactivity with HGM75 than with HGM72, MUC2 and HCM14. Little binding of HCM21 was observed in any specimens.ConclusionsThis study demonstrates that adenomas predominantly have a intestinal phenotype, but both types of adenocarcinomas retain some cells with a gastric phenotype during the early steps of neoplastic development.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2559.2000.00991.x

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0304-4165
    Keywords:
    Carbohydrate analysis ; Dansyl glyco-asparagine (Quail) ; Ovalbumin
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0304-4165(85)90058-3

    Articles: DFG German National Licenses
  8. 8
    Kato, Y. ; Iwase, H. ; Hotta, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-9861
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-9861(86)90607-7

    Articles: DFG German National Licenses
  9. 9
    Goso, Y. ; Hotta, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-9861
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/abbi.1993.1201

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    0006-291X
    Keywords:
    [abr] PCR; polymerase chain reaction ; [abr] PFK-M (-L); muscle (liver) type phosphofructokinase ; [abr] bp; base pair(s) ; [abr] kb; kilobase pairs
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(05)80931-3

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    1043-4666
    Keywords:
    cDNA ; canine ; cloning ; expression ; interleukin-8
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/1043-4666(94)90071-X

    Articles: DFG German National Licenses
  12. 12
    Kato, Y. ; Iwase, H. ; Hotta, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-2697
    Keywords:
    HPLC ; dansylated glycopeptides ; glycoproteins ; lectin affinity chromatography ; ovalbumin
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-2697(84)90835-2

    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    0003-2697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0003-2697(05)80034-X

    Articles: DFG German National Licenses
  14. 14
    Goso, Y. ; Hotta, K.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-2697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/abio.1994.1584

    Articles: DFG German National Licenses
  15. 15
    Hotta, K. ; Horikawa, M. ; Kurokawa, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-2697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-2697(70)90317-9

    Articles: DFG German National Licenses
  16. 16
    Hotta, K. ; Ishikawa, J. ; Ogata, T. ; Mizuno, S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0378-1119
    Keywords:
    C-〉T transition ; Recombinant DNA ; Streptomyces griseus ; Streptomyces kasugaenis ; acetyltransferase ; cryptic gene ; ist ; kan
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0378-1119(92)90548-4

    Articles: DFG German National Licenses
  17. 17
    Staff View
    ISSN:
    0378-1119
    Keywords:
    Recombinant DNA ; alternative splicing ; exon-intron boundary ; glycogenosis ; tissue-specific gene expression
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0378-1119(91)90262-A

    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-4534(94)91243-2

    Articles: DFG German National Licenses
  19. 19
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-4534(94)91241-6

    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-4534(94)91242-4

    Articles: DFG German National Licenses