Search Results - (Author, Cooperation:K. Hirahara)
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1Latest Papers from Table of Contents or Articles in PressR. Roychoudhuri ; K. Hirahara ; K. Mousavi ; D. Clever ; C. A. Klebanoff ; M. Bonelli ; G. Sciume ; H. Zare ; G. Vahedi ; B. Dema ; Z. Yu ; H. Liu ; H. Takahashi ; M. Rao ; P. Muranski ; J. G. Crompton ; G. Punkosdy ; D. Bedognetti ; E. Wang ; V. Hoffmann ; J. Rivera ; F. M. Marincola ; A. Nakamura ; V. Sartorelli ; Y. Kanno ; L. Gattinoni ; A. Muto ; K. Igarashi ; J. J. O'Shea ; N. P. Restifo
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-06-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Autoimmunity/immunology ; Basic-Leucine Zipper Transcription Factors/deficiency/genetics/*metabolism ; CD4-Positive T-Lymphocytes/cytology/immunology/metabolism ; Cell Differentiation/genetics/immunology ; Female ; Forkhead Transcription Factors/genetics/metabolism ; Homeostasis/genetics/*immunology ; Humans ; Immune Tolerance/genetics/immunology ; Inflammation/genetics/immunology/mortality/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; T-Lymphocytes, Regulatory/cytology/drug effects/*immunology/metabolism ; Transforming Growth Factor beta/pharmacologyPublished by: -
2Articles: DFG German National LicensesTamura, Y. ; Kawaguchi, J. ; Serizawa, N. ; Hirahara, K. ; Shiraishi, A. ; Nigi, H. ; Taniguchi, Y. ; Toda, M. ; Inouye, S. ; Takemori, T. ; Sakaguchi, M.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1365-2222Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background Japanese cedar (Cryptomeria japonica; CJ) pollinosis has been reported to occur naturally in Japanese monkeys (Macaca fuscata) as well as in humans. Most human patients and monkeys with pollinosis have specific IgE for Cry j 2, a major allergen of CJ pollen.Objective The main purpose of this study was to identify IgE B cell epitopes of Cry j 2 using a synthetic peptide in humans, monkeys and mice.Methods We synthesized 38 overlapping peptides that span the entire length of Cry j 2. We examined the B cell epitopes of Cry j 2 that are recognized by IgE in the sera of human patients and monkeys with pollinosis and immunized mice using synthetic peptides of Cry j 2. We also examined the reaction of Cry j 2-specific mouse monoclonal IgG antibodies to the peptides. Furthermore, we conducted a histamine release assay with leucocytes from a pollinosis patient using human serum albumin (HSA) conjugated with the peptides as a B cell epitope.Results We found that 16 of the 20 pollinosis patients who had specific IgE to Cry j 2 also exhibited IgE reaction with some Cry j 2 peptides. Of these 16 patients, 10 exhibited IgE reaction with Cry j 2 peptide no. 13 (121GQCKWVNGREICNDRDRPTA140). Five of the seven monkeys with CJ pollinosis exhibited a reaction with peptide no. 13. Furthermore, IgE in mice immunized with Cry j 2 and two mouse monoclonal IgG antibodies reacted with peptide no. 13. Peptide no. 13-conjugated HSA showed the release of histamine from basophils. Furthermore, to determine the minimum epitope in peptide no. 13, we conducted an enzyme-linked immunosorbent assay inhibition test. The core of the epitope in humans, monkeys and mice was 124KWVNGREI131.Conclusion We found that 124KWVNGREI131 is an important B cell epitope recognized by IgE in humans, monkeys and mice.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesMisfit dislocation microstructure and kinetics of HgCdTe/CdZnTe under tensile and compressive stressStaff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesMitsuhashi, H. ; Yahata, A. ; Uemoto, T. ; Kamata, A. ; Okajima, M. ; Hirahara, K. ; Beppu, T.
Amsterdam : ElsevierStaff ViewISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesShigenaka, K. ; Uemoto, T. ; Sugiura, L. ; Ichizono, K. ; Hirahara, K. ; Kanno, T. ; Saga, M.
Amsterdam : ElsevierStaff ViewISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesShigenaka, K. ; Kanno, T. ; Saga, M. ; Uemoto, T. ; Sugiura, L. ; Ichizono, K. ; Hirahara, K.
Amsterdam : ElsevierStaff ViewISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesOhsawa, K. ; Kimura, M. ; Kurosawa-Ohsawa, K. ; Takahashi, M. ; Koyama, M. ; Abiko, Y. ; Hirahara, K. ; Matsuishi, T. ; Tanaka, S.
Amsterdam : ElsevierStaff ViewISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0031-9201Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: GeosciencesPhysicsType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0031-9201Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: GeosciencesPhysicsType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0031-9201Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: GeosciencesPhysicsType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1434-6036Keywords: PACS. 61.14.Lj Convergent-beam electron diffraction, selected-area electron diffraction, nanodiffraction – 61.46.+w Nanoscale materials: clusters, nanoparticles, nanotubes, and nanocrystals – 81.07.De NanotubesSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract: We present a general and systematic method for determining the chiral indices of carbon nanotubes. This method relies on the semi-quantitative analysis of experimental selected area diffraction pattern intensities, together with extensive comparison with kinematic theory. We show how to retrieve the chiral indices of single walled or multiwalled carbon nanotubes, even when their radii are large (up to approximately 40 Å). All theoretical and experimental sources of errors are discussed. By discussing the experimental case of a double-walled carbon nanotube, we show how it is possible to determine the chiral indices of each of its constituant tubes independently, by analyzing parts of the diffraction pattern where the contributions of these tubes do not interfere. Using the parts where all the contributions do interfere, we successfully crosschecked independently the preceding determination.Type of Medium: Electronic ResourceURL: