Search Results - (Author, Cooperation:K. Hanson)
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1M. G. Aartsen ; R. Abbasi ; Y. Abdou ; M. Ackermann ; J. Adams ; J. A. Aguilar ; M. Ahlers ; D. Altmann ; J. Auffenberg ; X. Bai ; M. Baker ; S. W. Barwick ; V. Baum ; R. Bay ; J. J. Beatty ; S. Bechet ; J. Becker Tjus ; K. H. Becker ; M. L. Benabderrahmane ; S. BenZvi ; P. Berghaus ; D. Berley ; E. Bernardini ; A. Bernhard ; D. Bertrand ; D. Z. Besson ; G. Binder ; D. Bindig ; M. Bissok ; E. Blaufuss ; J. Blumenthal ; D. J. Boersma ; S. Bohaichuk ; C. Bohm ; D. Bose ; S. Boser ; O. Botner ; L. Brayeur ; H. P. Bretz ; A. M. Brown ; R. Bruijn ; J. Brunner ; M. Carson ; J. Casey ; M. Casier ; D. Chirkin ; A. Christov ; B. Christy ; K. Clark ; F. Clevermann ; S. Coenders ; S. Cohen ; D. F. Cowen ; A. H. Cruz Silva ; M. Danninger ; J. Daughhetee ; J. C. Davis ; M. Day ; C. De Clercq ; S. De Ridder ; P. Desiati ; K. D. de Vries ; M. de With ; T. DeYoung ; J. C. Diaz-Velez ; M. Dunkman ; R. Eagan ; B. Eberhardt ; B. Eichmann ; J. Eisch ; R. W. Ellsworth ; S. Euler ; P. A. Evenson ; O. Fadiran ; A. R. Fazely ; A. Fedynitch ; J. Feintzeig ; T. Feusels ; K. Filimonov ; C. Finley ; T. Fischer-Wasels ; S. Flis ; A. Franckowiak ; K. Frantzen ; T. Fuchs ; T. K. Gaisser ; J. Gallagher ; L. Gerhardt ; L. Gladstone ; T. Glusenkamp ; A. Goldschmidt ; G. Golup ; J. G. Gonzalez ; J. A. Goodman ; D. Gora ; D. T. Grandmont ; D. Grant ; A. Gross ; C. Ha ; A. Haj Ismail ; P. Hallen ; A. Hallgren ; F. Halzen ; K. Hanson ; D. Heereman ; D. Heinen ; K. Helbing ; R. Hellauer ; S. Hickford ; G. C. Hill ; K. D. Hoffman ; R. Hoffmann ; A. Homeier ; K. Hoshina ; W. Huelsnitz ; P. O. Hulth ; K. Hultqvist ; S. Hussain ; A. Ishihara ; E. Jacobi ; J. Jacobsen ; K. Jagielski ; G. S. Japaridze ; K. Jero ; O. Jlelati ; B. Kaminsky ; A. Kappes ; T. Karg ; A. Karle ; J. L. Kelley ; J. Kiryluk ; J. Klas ; S. R. Klein ; J. H. Kohne ; G. Kohnen ; H. Kolanoski ; L. Kopke ; C. Kopper ; S. Kopper ; D. J. Koskinen ; M. Kowalski ; M. Krasberg ; K. Krings ; G. Kroll ; J. Kunnen ; N. Kurahashi ; T. Kuwabara ; M. Labare ; H. Landsman ; M. J. Larson ; M. Lesiak-Bzdak ; M. Leuermann ; J. Leute ; J. Lunemann ; J. Madsen ; G. Maggi ; R. Maruyama ; K. Mase ; H. S. Matis ; F. McNally ; K. Meagher ; M. Merck ; T. Meures ; S. Miarecki ; E. Middell ; N. Milke ; J. Miller ; L. Mohrmann ; T. Montaruli ; R. Morse ; R. Nahnhauer ; U. Naumann ; H. Niederhausen ; S. C. Nowicki ; D. R. Nygren ; A. Obertacke ; S. Odrowski ; A. Olivas ; A. O'Murchadha ; L. Paul ; J. A. Pepper ; C. Perez de los Heros ; C. Pfendner ; D. Pieloth ; E. Pinat ; J. Posselt ; P. B. Price ; G. T. Przybylski ; L. Radel ; M. Rameez ; K. Rawlins ; P. Redl ; R. Reimann ; E. Resconi ; W. Rhode ; M. Ribordy ; M. Richman ; B. Riedel ; J. P. Rodrigues ; C. Rott ; T. Ruhe ; B. Ruzybayev ; D. Ryckbosch ; S. M. Saba ; T. Salameh ; H. G. Sander ; M. Santander ; S. Sarkar ; K. Schatto ; F. Scheriau ; T. Schmidt ; M. Schmitz ; S. Schoenen ; S. Schoneberg ; A. Schonwald ; A. Schukraft ; L. Schulte ; O. Schulz ; D. Seckel ; Y. Sestayo ; S. Seunarine ; R. Shanidze ; C. Sheremata ; M. W. Smith ; D. Soldin ; G. M. Spiczak ; C. Spiering ; M. Stamatikos ; T. Stanev ; A. Stasik ; T. Stezelberger ; R. G. Stokstad ; A. Stossl ; E. A. Strahler ; R. Strom ; G. W. Sullivan ; H. Taavola ; I. Taboada ; A. Tamburro ; A. Tepe ; S. Ter-Antonyan ; G. Tesic ; S. Tilav ; P. A. Toale ; S. Toscano ; E. Unger ; M. Usner ; N. van Eijndhoven ; A. Van Overloop ; J. van Santen ; M. Vehring ; M. Voge ; M. Vraeghe ; C. Walck ; T. Waldenmaier ; M. Wallraff ; C. Weaver ; M. Wellons ; C. Wendt ; S. Westerhoff ; N. Whitehorn ; K. Wiebe ; C. H. Wiebusch ; D. R. Williams ; H. Wissing ; M. Wolf ; T. R. Wood ; K. Woschnagg ; D. L. Xu ; X. W. Xu ; J. P. Yanez ; G. Yodh ; S. Yoshida ; P. Zarzhitsky ; J. Ziemann ; S. Zierke ; M. Zoll
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-11-23Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Alicia M. Hanson, K. L. Iresha Sampathi Perera, Jaekyoon Kim, Rajesh K. Pandey, Noreena Sweeney, Xingyun Lu, Andrea Imhoff, Alexander Craig Mackinnon, Adam J. Wargolet, Rochelle M. Van Hart, Karyn M. Frick, William A. Donaldson, Daniel S. Sem
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-06-12Publisher: American Chemical Society (ACS)Topics: Chemistry and PharmacologyPublished by: -
3Visick, K. L., Hodge-Hanson, K. M., Tischler, A. H., Bennett, A. K., Mastrodomenico, V.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-07-03Publisher: The American Society for Microbiology (ASM)Print ISSN: 0099-2240Electronic ISSN: 1098-5336Topics: BiologyPublished by: -
4Staff View
ISSN: 1439-0523Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: This study examines the performance of somaclonal spring wheat (Triticum aestivum L.) lines developed through culture of somatic embryos. Twenty-nine breeder lines of the spring wheat cv. ‘HY320’ were compared to 51 somaclonal lines of the same cultivar. Somaclonal lines were derived from 27 individual embryos (with up to four lines in each “family”). Somaclonal and breeder lines were evaluated in five field experiments in western Canada. Somaclonal lines were more variable than breeder lines for most agronomic, yield component and quality characters, suggesting that variability among somaclonal lines resulted partly from the tissue culture process. Somaclonal lines yielded, on average, 11 % less than breeder lines. Somaclonal lines had 3.8 % fewer spikelets per spike, 6.5 % fewer kernels per spike and kernels which were 2.7 % lighter. Somaclonal lines had greater test weight, protein concentration, and sedimentation values, and harder kernels.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Oospores of Phytophthora infestans were produced in potato leaf discs floating on metalaxyl solution (100 μg mL−1 a.i.) and inoculated with all combinations of two metalaxyl-sensitive and two -resistant parental isolates. Numbers of oospores produced varied between different matings, depending on parents, in the absence of the fungicide and when metalaxyl was added 0, 7, 14 and 21 days after inoculation. Oospores were not produced when metalaxyl was added at the time of inoculation (0 days) when either one or both parents were sensitive to metalaxyl. In two of three such matings further oospore formation was arrested when metalaxyl was added either 7 or 14 days after inoculation. Oospores extracted from leaf discs 14, 21 and 28 days after inoculation were assessed for germination on water agar after 21 days. Germination of oospores from water control treatments varied between 6 and 30% depending on the cross. Germination was significantly reduced in oospores of metalaxyl-sensitive parents extracted 28 days after inoculation of leaf discs treated with metalaxyl 0, 7 and 14 days after inoculation compared with the 21-day treatment. Minimal differences in germination were observed for oospores from the mating of resistant parents irrespective of metalaxyl treatment, although germination was generally low, not exceeding 8.5%.Type of Medium: Electronic ResourceURL: -
6Mahadevan, U. ; Kane, S. ; Sandborn, W. J. ; Cohen, R. D. ; Hanson, K. ; Terdiman, J. P. ; Binion, D. G.
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Aim: To study the effects of infliximab on pregnancy and foetal outcome.Methods: We conducted a retrospective chart review of women with Crohn's disease treated intentionally with infliximab during pregnancy. The primary outcome measure was the occurrence of congenital malformations. Secondary outcome measures were the rate of premature birth, low-birth weight, small for gestational age infants, intrauterine growth retardation and caesarean section.Results: Ten women were identified. Eight women received maintenance infliximab infusions throughout their pregnancy and two women received their initial infliximab infusions during pregnancy. All 10 pregnancies ended in live births. No infants had congenital malformations, intrauterine growth retardation or small for gestational age parameters. Three infants were premature and one had low-birth weight. Eight women had a caesarean section.Conclusions: This is the first reported series of intentional infliximab use throughout pregnancy. These data, combined with other studies of inadvertent use of infliximab during pregnancy, suggest that the benefits of infliximab in achieving response and maintaining remission in mothers with Crohn's disease may outweigh the risk to the foetus of exposure to the drug. Further prospective data collection will be helpful to confirm these findings.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0003-9861Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0277-9536Keywords: Bamako Initiative ; affordability ; community financing ; cost recovery ; qualitySource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
10Frick, P.J. ; Lahey, B.B. ; Loeber, R. ; Tannenbaum, L. ; Van Horn, Y. ; Christ, M.A.G. ; Hart, E.A. ; Hanson, K.
Amsterdam : ElsevierStaff ViewISSN: 0272-7358Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Leaf discs in vitro, whole plants growing in a walk-in plastic tunnel, and field plots of up to 10 cultivars of potato were inoculated with an A1 and an A2 isolate of Phytophthora infestans of recent UK origin. Numbers of oospores produced varied between repeated experiments involving leaf discs of four cultivars but ranking was unchanged 20 days after inoculation. Maximum mean numbers of oospores (approximately 20 000 per cm2 of leaf) were formed in the highly susceptible cv. Home Guard, with progressively fewer in Maris Piper, Cara, and the fewest in leaf discs of the highly resistant cv. Stirling. In Stirling, the number of oospores increased from approximately 1000–16 000 per cm2 of leaf between 11 and 30 days post-inoculation. When leaf discs of 10 cultivars were inoculated, numbers of oospores were highest in cultivars with medium levels of race-nonspecific resistance such as Desiree and Record. On Maris Piper and Cara, but not Home Guard and Stirling, asexual sporulation was significantly (P 〈 0.05) lower following dual inoculation with A1 and A2 isolates than following inoculation with either isolate alone. The highly susceptible cultivars Home Guard and Bintje were rapidly destroyed after inoculation of field and tunnel-grown whole plants, and oospores were not observed. Oospores occurred in leaflets of various cultivars with medium levels of resistance to late-blight, and in stems of all cultivars except Stirling. Twenty-five isolates from single blight lesions from leaflets, and 16 from blighted tubers from the plastic tunnel-grown plants, were characterized for mitochondrial and nuclear DNA polymorphisms. All but one were identical to parental isolates or confirmed as contaminants from an adjacent late-blight-affected tuber dump. One isolate, however, obtained from cv. Pimpernel 20 days after inoculation, may have been a recombinant between the A1 and A2 parental isolates, or alternatively a product of selfing or somatic recombination of the A1 parent.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Résumé L'activité de l'uricase et des tyrosinases d'origine végétale et animale est diminuée par irradiation UV (2537 Å). Il existe une relation exponentielle entre l'activité enzymatique relative et la quantité de rayonnement. Il n'a pas été possible de mettre en évidence une relation entre la perte d'activité de la tyrosinase végétale des échantillons irradiés et la teneur en cuivre de ces derniers.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1432-1998Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Esophageal intramural pseudodiverticulosis (EIPD) is an uncommon entity in which distended esophageal mucous glands form flask-like outpouchings from the esophagus. Its relationship with esophagitis, gastroesophageal reflux, and benign stricture suggests that it is a consequence of inflammation [1].Type of Medium: Electronic ResourceURL: -
14Hatsukami, D.K. ; Pentel, P.R. ; Glass, J. ; Nelson, R. ; Brauer, L.H. ; Crosby, R. ; Hanson, K.
Amsterdam : ElsevierStaff ViewISSN: 0091-3057Keywords: Human laboratory ; Methodology ; Smoked cocaine-baseSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0165-7992Keywords: Chinese hamster ovary cells ; Chromatid interchanges ; Ionising radiation ; Neurospora endonucleaseSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1432-0428Keywords: Keywords Weight loss, weight gain, weight regain, weight maintenance, weight cycling, insulin resistance, acute insulin response, disposition index, glucose clamp, obesity.Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Aims/hypothesis. We aimed to quantify changes in insulin action and insulin secretion associated with long-term gain, loss, regain, and maintenance of body weight in subjects with normal (NGT) or impaired (IGT) glucose tolerance.¶Methods. Insulin action (hyperinsulinaemic clamp) and insulin secretion (intravenous glucose challenge) were measured longitudinally in 209 Pima Indians [body weight 94.4 ± 22.8 kg (means ± SD) 89 women/120 men, 151 NGT/58 IGT], who either lost (n = 110) or gained (n = 99) weight (–23 % to + 29 %) over 2.6 ± 2.0 years. Insulin action and insulin secretion were reassessed on a third occasion in 33 subjects who lost at least 5 % body weight over 1.5 ± 0.8 years and then either regained or maintained weight over the subsequent 1.8 ± 1.1 years.¶Results. There was a linear negative relation between changes in body weight and changes in insulin-stimulated glucose disposal in subjects with normal glucose tolerance (r = – 0.51, p 〈 0.0001) and impaired glucose tolerance (r = – 0.54, p 〈 0.0001). In contrast, changes in the acute insulin response were positively related to weight changes in subjects with normal glucose tolerance (r = + 0.26, p 〈 0.005) but negatively in those with impaired glucose tolerance (r = – 0.51, p 〈 0.0001). Improvements in insulin action after an average of 10 % weight loss were lost with weight regain but largely preserved with weight maintenance.¶Conclusion/interpretation. Improvements in insulin action are proportional to the amount of weight loss, similar in magnitude to the impairment in insulin action with weight gain, preserved with long-term weight maintenance and similar between subjects with normal and with impaired glucose tolerance. Weight gain could, however, have more detrimental effects in people with impaired glucose tolerance, in whom insulin secretion decreases rather than increases to compensate for the decreased insulin action. [Diabetologia (2000) 43: 36–46]Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1432-2099Source: Springer Online Journal Archives 1860-2000Topics: BiologyPhysicsNotes: Summary The spectrum of nuclear nucleases in control and irradiated (4 Gy) thymocytes has been investigated. Using the method of SDS electrophoresis of nuclear proteins in3H - DNA-polyacrylamide gels a number of polypeptides of MW. 35, 32, 17.7, 17.2 and 16.4 kDa possessing nuclease activity were found. The 35 kDa enzyme is only active in the presence of Ca2+ and Mg2+ ions. In response to cycloheximide injection (3 mg/100 g body weight) and irradiation, we did not detect the 35 kDa nuclease activity. Nucleases of 32, 17.7, 17.2 and 16.4 kDa are active in the presence of Ca2+ ions. The activities of these nucleases increases 60 min after irradiation. These nucleases were also found in the fraction of polydeoxyribonucleotide (PDN).Type of Medium: Electronic ResourceURL: -
18Zherbin, E. A. ; Chukhlovin, A. B. ; Köteles, G. J. ; Kubasova, T. A. ; Vashchenko, V. I. ; Hanson, K. P.
Springer
Published 1986Staff ViewISSN: 1432-0738Keywords: Cadmium chloride ; Thymocytes ; Ionizing radiation ; Cell damage ; Combined effectsSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Effects of cadmium chloride upon 3H-Con A binding, number of autologous rosette-forming cells (ARFC), cell viability and the degree of DNA supercoiling were studied in normal and irradiated thymic lymphoid cells, isolated from rats and incubated up to 6 h in vitro. Cd (10–100 μM) did not significantly alter the patterns of surface markers and viability of normal thymocytes, as measured by supravital staining or nuclear pyknotic criteria. The following effects of Cd were noted for irradiated thymic cells: 1) Cd ions (25 μM) caused elimination of radiation-induced increase of Con A binding; 2) the characteristic loss of ARFC receptors, like development of nuclear pyknosis, was prevented in the presence of CdCl2 (10–100 μM); 3) the postradiation relaxation of nuclear supercoiled DNA was distinctly less pronounced with Cd. Possible reasons for these effects of Cd are discussed. Irradiated lymphoid cells are proposed as a suitable experimental model for the studies of different toxic actions of Cd and other heavy metals.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1573-689XSource: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1573-6776Source: Springer Online Journal Archives 1860-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: Summary Polyethylene glycol 6000 mediated protoplast fusion between an alkane degrader Acinetobacter sp. A3, and a naphthalene degrader, Pseudomonas putida DP99 , resulted in fusants capable of degrading both hydrocarbons and were morphologically similar to Acinetobacter sp. A3. While fusant F4/13 and Pseudomonas putida DP99 degraded over 98% of naphthalene provided by the end of five days, tetradecane degradation by fusant F4/13 was 82% compared to 77% by Acinetobacter sp. A3 in the same time period. Also, while from naphthalene +tetradecane mixture, fusant F4/13 could degrade 99% and 53% of naphthalene and tetradecane respectively, both the parent strains together could degrade over 99% naphthalene but only about 16% tetradecane.Type of Medium: Electronic ResourceURL: