Search Results - (Author, Cooperation:K. H. Yu)
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1Latest Papers from Table of Contents or Articles in PressG. M. DeNicola ; F. A. Karreth ; T. J. Humpton ; A. Gopinathan ; C. Wei ; K. Frese ; D. Mangal ; K. H. Yu ; C. J. Yeo ; E. S. Calhoun ; F. Scrimieri ; J. M. Winter ; R. H. Hruban ; C. Iacobuzio-Donahue ; S. E. Kern ; I. A. Blair ; D. A. Tuveson
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-07-08Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing/genetics/metabolism ; Alleles ; Animals ; Antioxidants/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Cell Transformation, Neoplastic/genetics/*metabolism/*pathology ; Cells, Cultured ; Cytoskeletal Proteins/genetics/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Fibroblasts/metabolism ; Genes, myc/genetics ; Humans ; Intracellular Signaling Peptides and Proteins/genetics/metabolism ; JNK Mitogen-Activated Protein Kinases/metabolism ; MAP Kinase Signaling System ; Mice ; Mitogen-Activated Protein Kinase Kinases/metabolism ; NF-E2-Related Factor 2/deficiency/genetics/*metabolism ; NIH 3T3 Cells ; Oncogenes/*genetics ; Oxidation-Reduction ; Pancreatic Neoplasms/genetics/*metabolism/*pathology ; Proto-Oncogene Proteins B-raf/genetics/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics/metabolism ; Reactive Oxygen Species/*metabolismPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-01-12Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: Surface physics, nanoscale physics, low-dimensional systemsPublished by: -
3Latest Papers from Table of Contents or Articles in PressM. Gulde ; S. Schweda ; G. Storeck ; M. Maiti ; H. K. Yu ; A. M. Wodtke ; S. Schafer ; C. Ropers
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-07-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
4Latest Papers from Table of Contents or Articles in PressPietrzak, B., Ward, A., Cheung, M. K., Schwendimann, B. A., Mollaoglu, G., Duong, M. T., Ulltveit-Moe, N., Allareddy, V., Dutton-Regester, K., Zhang, J., Scult, M. A., Naz, S., Singh, P. C., Yan, H. Y., Isaacson, K., Dennis, A. F., Al-Humaidan, E. I., Beardsley, F. R., Lo, C., Sood, P., Jones, T., Nieuwenhuis, R., Ali, B. A., Yu, K.-H., Arthur, P. K., Kumar, B., Chen, A., Buschke, F., Cingl, L., Zaidi, S. S.-e.-A., O'Mullane, A. P., Coetzee, V., Konstantinides, N.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-06-29Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
5Latest Papers from Table of Contents or Articles in PressHu, Z. I., Shia, J., Stadler, Z. K., Varghese, A. M., Capanu, M., Salo-Mullen, E., Lowery, M. A., Diaz, L. A., Mandelker, D., Yu, K. H., Zervoudakis, A., Kelsen, D. P., Iacobuzio-Donahue, C. A., Klimstra, D. S., Saltz, L. B., Sahin, I. H., O'Reilly, E. M.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-03-16Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
6Articles: DFG German National LicensesLuk, N. M. ; Ho, L. C. ; Choi, C. L. ; Wong, K. H. ; Yu, K. H. ; Yeung, W. K.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2230Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Cutaneous melanoma is rare among Chinese people. The clinicopathologic features and prognostic factors of 63 Hong Kong ethnic Chinese cases were analysed. We found that the mean age of onset was 65.5 years with a female : male ratio of 1 : 1.33. Forty-two (66.7%) patients had their tumours on their feet. More than 50% had the acral lentiginous histologic subtype. The mean tumour thickness was 5.73 mm with 92.1% (n = 58) having a Clark's level of III or more. Of the tumours, 57.1% were ulcerated. Stage I and II tumours comprised 73% (n = 46) while stage III and IV tumours made up of 26% (n = 17). The 1-, 3- and 5-year survival rates were 75%, 30% and 17%, respectively. Univariate analysis for overall survival showed that advanced clinical staging (stage III and IV), tumour ulceration and thicker tumour (〉4 mm) had a significantly poorer prognosis. Multivariate analysis demonstrated that advanced clinical staging was the most decisive prognostic factor followed by tumour ulceration. Our study showed that cutaneous melanoma in Chinese people is a disease predominantly of an older age group with the acral lentiginous histologic type located mainly on the feet. The prognosis depends on clinical staging and ulceration status.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesLuk, N. M. ; Yu, K. H. ; Yeung, W. K. ; Choi, C. L. ; Teo, M. L.
Oxford, UK : Blackwell Science Ltd
Published 2003Staff ViewISSN: 1365-2230Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary Six patients with extramammary Paget's disease were treated with curative intent radiotherapy. Two of the patients had associated underlying adenocarcinoma. Radiotherapy was given as primary treatment (two patients), definitive treatment for postexcisional relapse (three patients) and adjuvant treatment (one patient). Radiotherapy techniques included high dose rate mould brachytherapy, electron beam, superficial X-ray and photon treatments. Follow-up durations after radiotherapy were 1.2–14.8 years. Complete response was obtained in five patients while one patient had a partial response. Marginal failure occurred in one complete-responder who was successfully salvaged by surgery. The two patients with underlying adenocarcinoma died of distant metastasis. Radiotherapy side effects were acute confluent wet desquamation and mild late skin atrophy. Our results confirmed the useful role of radiotherapy in the management of extramammary Paget's disease.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesLuk, N. M. ; Yu, K. H. ; Choi, C. L. ; Yeung, W. K.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2230Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Nasopharyngeal carcinoma (NPC) is a common malignancy among southern Chinese. The tumours are mostly undifferentiated carcinomas and are associated with Epstein–Barr virus. Patients present with a blood-stained postnasal discharge, impaired hearing, tinnitus or cervical lymph node enlargement. Radiotherapy with or without chemotherapy is the standard treatment. Though metastatic lung, bone or liver disease is not uncommon on relapse, skin metastasis is rarely reported. The small number of reports in the literature are either brief or have only a few patients. In this report, we describe our series of four Hong Kong Chinese patients with NPC who had distant cutaneous metastases.Type of Medium: Electronic ResourceURL: