Search Results - (Author, Cooperation:K. Downes)
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1L. Chen ; M. Kostadima ; J. H. Martens ; G. Canu ; S. P. Garcia ; E. Turro ; K. Downes ; I. C. Macaulay ; E. Bielczyk-Maczynska ; S. Coe ; S. Farrow ; P. Poudel ; F. Burden ; S. B. Jansen ; W. J. Astle ; A. Attwood ; T. Bariana ; B. de Bono ; A. Breschi ; J. C. Chambers ; F. A. Choudry ; L. Clarke ; P. Coupland ; M. van der Ent ; W. N. Erber ; J. H. Jansen ; R. Favier ; M. E. Fenech ; N. Foad ; K. Freson ; C. van Geet ; K. Gomez ; R. Guigo ; D. Hampshire ; A. M. Kelly ; H. H. Kerstens ; J. S. Kooner ; M. Laffan ; C. Lentaigne ; C. Labalette ; T. Martin ; S. Meacham ; A. Mumford ; S. Nurnberg ; E. Palumbo ; B. A. van der Reijden ; D. Richardson ; S. J. Sammut ; G. Slodkowicz ; A. U. Tamuri ; L. Vasquez ; K. Voss ; S. Watt ; S. Westbury ; P. Flicek ; R. Loos ; N. Goldman ; P. Bertone ; R. J. Read ; S. Richardson ; A. Cvejic ; N. Soranzo ; W. H. Ouwehand ; H. G. Stunnenberg ; M. Frontini ; A. Rendon
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-09-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Alternative Splicing ; Cell Lineage/*genetics ; Genetic Variation ; Hematopoiesis/*genetics ; Hematopoietic Stem Cells/*cytology/metabolism ; Humans ; NFI Transcription Factors/genetics/metabolism ; RNA-Binding Proteins/metabolism ; Thrombopoiesis/genetics ; TranscriptomePublished by: -
2S. Saeed ; J. Quintin ; H. H. Kerstens ; N. A. Rao ; A. Aghajanirefah ; F. Matarese ; S. C. Cheng ; J. Ratter ; K. Berentsen ; M. A. van der Ent ; N. Sharifi ; E. M. Janssen-Megens ; M. Ter Huurne ; A. Mandoli ; T. van Schaik ; A. Ng ; F. Burden ; K. Downes ; M. Frontini ; V. Kumar ; E. J. Giamarellos-Bourboulis ; W. H. Ouwehand ; J. W. van der Meer ; L. A. Joosten ; C. Wijmenga ; J. H. Martens ; R. J. Xavier ; C. Logie ; M. G. Netea ; H. G. Stunnenberg
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-09-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Binding Sites/genetics ; Cell Differentiation/*genetics ; Deoxyribonuclease I/chemistry ; *Epigenesis, Genetic ; Genomic Imprinting ; Humans ; Immunity, Innate/*genetics ; Immunologic Memory ; Inflammasomes/genetics/immunology ; Macrophages/*cytology/immunology ; Mice ; Monocytes/*cytology/immunology ; Transcription Factors/metabolism ; beta-Glucans/immunologyPublished by: -
3Ngo, T. T. M., Moufarrej, M. N., Rasmussen, M.-L. H., Camunas-Soler, J., Pan, W., Okamoto, J., Neff, N. F., Liu, K., Wong, R. J., Downes, K., Tibshirani, R., Shaw, G. M., Skotte, L., Stevenson, D. K., Biggio, J. R., Elovitz, M. A., Melbye, M., Quake, S. R.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-06-08Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Genetics, Medicine, DiseasesPublished by: -
4Revel-Vilk, S., Shai, E., Turro, E., Jahshan, N., Hi-Am, E., Spectre, G., Daum, H., Kalish, Y., Althaus, K., Greinacher, A., Kaplinsky, C., Izraeli, S., Mapeta, R., Deevi, S. V. V., Jarocha, D., Ouwehand, W. H., Downes, K., Poncz, M., Varon, D., Lambert, M. P.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-10-26Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Thrombocytopenia, Platelets and Thrombopoiesis, Clinical Trials and ObservationsPublished by: -
5Norris, F. H. ; Panitch, H. S. ; Denys, E. H. ; Downes, K. ; Cantell, K. ; Smith, R. A.
Springer
Published 1986Staff ViewISSN: 1432-1459Keywords: Encephalitis ; Virus ; Interferon ; Measles panencephalitis ; SSPESource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary A child with subacute sclerosing panencephalitis (SSPE) received intraventricular alpha interferon (IFN) as experimental treatment. The course was monitored by colleagues in pediatric neurology, neuro-opthalmology and clinical psychology, also by monthly EEGS and brain CT scans. Two courses of IFN were administered. During the first course, improvement occurred nearly to the premorbid level of function. About 1 month after this trial was stopped, a severe recrudescence rapidly produced a thalamic state. A second trial of IFN resulted in less improvement. When the brain CT showed severe degeneration, the second trial was stopped. Intraventricular administration of alpha IFN was well tolerated in both courses of therapy. Alpha IFN has promise in the treatment of SSPE but the optimal dosage and duration of treatment are undetermined.Type of Medium: Electronic ResourceURL: