Search Results - (Author, Cooperation:K. Doronin)
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1K. Doronin ; J. W. Flatt ; N. C. Di Paolo ; R. Khare ; O. Kalyuzhniy ; M. Acchione ; J. P. Sumida ; U. Ohto ; T. Shimizu ; S. Akashi-Takamura ; K. Miyake ; J. W. MacDonald ; T. K. Bammler ; R. P. Beyer ; F. M. Farin ; P. L. Stewart ; D. M. Shayakhmetov
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-09-29Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adenoviridae Infections/*immunology/metabolism/virology ; Adenoviruses, Human/genetics/*immunology/*metabolism ; Animals ; CHO Cells ; Capsid Proteins/chemistry/genetics/metabolism ; Cell Line, Tumor ; Cricetinae ; Cricetulus ; Cryoelectron Microscopy ; Cytokines/metabolism ; Factor X/chemistry/*metabolism ; Gene Expression Profiling ; Gene Expression Regulation ; Hepatocytes/virology ; Humans ; *Immunity, Innate ; Macrophages/metabolism/virology ; Mice ; Mice, Inbred C57BL ; Molecular Dynamics Simulation ; Mutation ; NF-kappa B/metabolism ; Signal Transduction ; Virus InternalizationPublished by: -
2Staff View
ISSN: 1432-8798Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary The genomic region of the avian adenovirus FAV1 (CELO) encoding the precursor to virion structural protein VI (pVI) and the major capsid protein hexon has been sequenced. The 223-unit sequence of the CELO pVI protein has two potential Ad endoproteinase cleavage sites and a conserved C-terminal sequence including the Cys residue supposedly involved in endoproteinase activation. The CELO hexon gene sequence predicts a 942-residue protein (106.7 kDa). Multiple sequence alignment with other six known hexon protein sequences (human, bovine, murine, and avian) reveals high overall homology. The identity is highest in the regions corresponding to the pedestals which form the base of the hexon, and lowest in the regions corresponding to the loops which are exposed on the outer surface of the virion.Type of Medium: Electronic ResourceURL: